|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.197
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.173
|
Fly |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.150
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.150
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.142
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.121
|
Worm |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.111
|
Worm Fly |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.105
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.104
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.104
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.101
|
Fly |
|
|
associative learning
|
GO:0008306 |
1 |
0.101
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.097
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.092
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.092
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.091
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.091
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.090
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.088
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.085
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.084
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.083
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.082
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.081
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.081
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.079
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.079
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.078
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.077
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.076
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.072
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.072
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.071
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.071
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.071
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.071
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.070
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.068
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.064
|
Human Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.064
|
Fly |
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.063
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.062
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.061
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.061
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.061
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.060
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.060
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.060
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.060
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.058
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.057
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.056
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.055
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.055
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.055
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.055
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.055
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.055
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.054
|
Human |
|
|
mating
|
GO:0007618 |
1 |
0.054
|
Fly |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.054
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.053
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.053
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.053
|
Mouse |
|
|
oocyte development
|
GO:0048599 |
1 |
0.053
|
Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.053
|
Human |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.052
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.052
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.052
|
|
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
16 |
0.052
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.051
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.050
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.050
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.050
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.050
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.049
|
Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.049
|
|
|
|
memory
|
GO:0007613 |
3 |
0.048
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.048
|
Human |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.048
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.047
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.047
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.047
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.047
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.047
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.047
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.047
|
Human Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.047
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.046
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.046
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.045
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.045
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.045
|
Human |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.044
|
Human |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.044
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.044
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.044
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.043
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.043
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.043
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.043
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.043
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.043
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.042
|
Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.042
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.042
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.042
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.041
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.041
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.041
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.040
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.040
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.040
|
Human |
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.040
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.040
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.040
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.040
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.040
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.039
|
Fly |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.039
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.038
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.038
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.038
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.038
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.038
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.038
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.037
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.037
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.037
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.037
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.037
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.036
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.036
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.036
|
Fly |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.035
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.035
|
Fly |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.035
|
Fly |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.035
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.034
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.034
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.034
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.034
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.034
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.034
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.034
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.034
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.034
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.034
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.034
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.034
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.033
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.033
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.033
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.033
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.033
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.033
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
1 |
0.032
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.032
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.032
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.031
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.031
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.031
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
43 |
0.031
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.031
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.031
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.031
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.031
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.031
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.030
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.030
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.030
|
|
|
|
positive regulation of organ growth
|
GO:0046622 |
2 |
0.030
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.030
|
Human |
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.030
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.030
|
Mouse Fly |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.029
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.029
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.029
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.029
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.029
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.028
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.028
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.028
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.028
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.028
|
Human Fly |
|
|
growth
|
GO:0040007 |
202 |
0.028
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.028
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.028
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.028
|
Human |
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.028
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.028
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.027
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.027
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.027
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.027
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.027
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.027
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.027
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
Fly |
|
|
organelle fission
|
GO:0048285 |
149 |
0.026
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.026
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.026
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.026
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.026
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.025
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.025
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.025
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.025
|
Human |
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.025
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.025
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.025
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.025
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.025
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.025
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.025
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.025
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.025
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.024
|
|
|
|
system process
|
GO:0003008 |
349 |
0.024
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.024
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.024
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.024
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.024
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.024
|
|
|
|
translation
|
GO:0006412 |
132 |
0.024
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.024
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.024
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.024
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.024
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.023
|
|
|
|
olfactory bulb interneuron differentiation
|
GO:0021889 |
2 |
0.023
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.023
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.023
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.023
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.023
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.023
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.023
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.023
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.023
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.023
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.023
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.023
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.023
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
15 |
0.022
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.022
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.022
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.022
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.022
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.022
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.022
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.022
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.022
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.022
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.022
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.022
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.021
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.021
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.021
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.021
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.021
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.021
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.021
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.021
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.021
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.021
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.021
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.021
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.021
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.021
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.021
|
|
|
|
chemical homeostasis within a tissue
|
GO:0048875 |
3 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
positive regulation of cardiac muscle tissue growth
|
GO:0055023 |
2 |
0.020
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.020
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.020
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.020
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.020
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
23 |
0.020
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.020
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.020
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.020
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.020
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.019
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.019
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.019
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.019
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.019
|
Human |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.019
|
Fly |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.019
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.019
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.019
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.019
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.019
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.019
|
|
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.019
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.019
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.019
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.019
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.019
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.019
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.019
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.019
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.019
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.019
|
Worm Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.019
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.019
|
Fly |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.019
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.019
|
|
|
|
directional locomotion
|
GO:0033058 |
1 |
0.019
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.019
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.019
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.019
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.019
|
|
|
|
male genitalia development
|
GO:0030539 |
1 |
0.018
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.018
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.018
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.018
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.018
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.018
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.018
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.018
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.018
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.018
|
|
|
|
head development
|
GO:0060322 |
108 |
0.018
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.018
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.018
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.018
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.018
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.018
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.018
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.018
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.018
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.018
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.018
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.018
|
Human |
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.018
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.018
|
Mouse Fly |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.017
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.017
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.017
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.017
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.017
|
Human |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.017
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.017
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.017
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.017
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.017
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
1 |
0.017
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.017
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.017
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.017
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.017
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.017
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.017
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.017
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.017
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.017
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.017
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.017
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.017
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.017
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.017
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.017
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.017
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
23 |
0.017
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.017
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.017
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.016
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.016
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.016
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.016
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.016
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.016
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.016
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.016
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.016
|
|
|
|
stat protein import into nucleus
|
GO:0007262 |
2 |
0.016
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.016
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.016
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.016
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.016
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.016
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.016
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.016
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.016
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.016
|
|
|
|
surfactant homeostasis
|
GO:0043129 |
3 |
0.016
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.016
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.016
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.016
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.016
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.016
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.016
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.016
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.016
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.016
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.016
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.016
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.016
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.016
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.016
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.016
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.016
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.015
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.015
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.015
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.015
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.015
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.015
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.015
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.015
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.015
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.015
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.015
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.015
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.015
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.015
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.015
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.015
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.014
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.014
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.014
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.014
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.014
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.014
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.014
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.014
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.014
|
Fly |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.014
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.014
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.014
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.014
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.014
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.014
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.014
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.014
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.014
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.014
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.014
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.014
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.014
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.014
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.014
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.014
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.014
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.014
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.014
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.014
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.014
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.014
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.014
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.014
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.014
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.014
|
Mouse Fly |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.014
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.014
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.014
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.014
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.013
|
|
|
|
mammary gland epithelial cell differentiation
|
GO:0060644 |
1 |
0.013
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.013
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.013
|
Fly |
|
|
cilium organization
|
GO:0044782 |
68 |
0.013
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.013
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.013
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.013
|
|
