Homo sapiens

24 known processes

METAP1

methionyl aminopeptidase 1

(Aliases: KIAA0094,MAP1A,MetAP1A,DKFZp781C0419)

METAP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate biosynthetic process GO:1901293 109 0.113
organonitrogen compound biosynthetic process GO:1901566 200 0.107
positive regulation of developmental process GO:0051094 314 0.103
nucleotide biosynthetic process GO:0009165 109 0.097
regulation of cellular amine metabolic process GO:0033238 11 0.096
purine nucleotide biosynthetic process GO:0006164 84 0.094
cellular amino acid metabolic process GO:0006520 116 0.092
nitrogen compound transport GO:0071705 191 0.084
regulation of cell cycle process GO:0010564 266 0.066
microtubule cytoskeleton organization GO:0000226 176 0.066
histone methylation GO:0016571 60 0.062
cell projection organization GO:0030030 252 0.062
positive regulation of cellular amine metabolic process GO:0033240 7 0.061
purine containing compound biosynthetic process GO:0072522 88 0.061
neuron development GO:0048666 113 0.060
neuron projection development GO:0031175 106 0.059
response to oxygen containing compound GO:1901700 369 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
carbohydrate derivative biosynthetic process GO:1901137 207 0.053
carbohydrate metabolic process GO:0005975 207 0.052
post embryonic development GO:0009791 2 0.052
chromatin organization GO:0006325 351 0.051
endomembrane system organization GO:0010256 196 0.050
microtubule based process GO:0007017 210 0.050
cell morphogenesis GO:0000902 296 0.050
macromolecule methylation GO:0043414 97 0.049
generation of neurons GO:0048699 152 0.049
response to biotic stimulus GO:0009607 276 0.049
small molecule catabolic process GO:0044282 92 0.049
cell cell signaling GO:0007267 155 0.049
amine metabolic process GO:0009308 44 0.048
regulation of growth GO:0040008 165 0.048
cellular ketone metabolic process GO:0042180 80 0.048
defense response GO:0006952 315 0.047
endocytosis GO:0006897 159 0.047
secretion by cell GO:0032940 226 0.046
protein methylation GO:0006479 74 0.045
cellular amine metabolic process GO:0044106 41 0.044
single organism carbohydrate metabolic process GO:0044723 193 0.044
mitotic cell cycle GO:0000278 326 0.043
cell development GO:0048468 328 0.043
secretion GO:0046903 254 0.043
neuron differentiation GO:0030182 138 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.043
glycoprotein metabolic process GO:0009100 110 0.042
response to external biotic stimulus GO:0043207 261 0.041
ribose phosphate biosynthetic process GO:0046390 82 0.040
morphogenesis of embryonic epithelium GO:0016331 4 0.040
regulation of meiotic cell cycle GO:0051445 4 0.039
response to other organism GO:0051707 261 0.038
mitotic cell cycle process GO:1903047 286 0.037
ribonucleotide biosynthetic process GO:0009260 81 0.035
cell part morphogenesis GO:0032990 137 0.034
glycosylation GO:0070085 71 0.034
neuromuscular junction development GO:0007528 3 0.033
nervous system development GO:0007399 293 0.033
organophosphate biosynthetic process GO:0090407 163 0.033
cell projection morphogenesis GO:0048858 129 0.033
negative regulation of apoptotic process GO:0043066 316 0.032
chromatin modification GO:0016568 298 0.032
embryo development GO:0009790 123 0.032
locomotory behavior GO:0007626 1 0.032
regulation of cell cycle GO:0051726 393 0.032
system process GO:0003008 349 0.031
cellular component morphogenesis GO:0032989 314 0.031
nuclear division GO:0000280 128 0.031
organelle localization GO:0051640 84 0.030
oocyte development GO:0048599 1 0.030
intracellular protein transport GO:0006886 270 0.030
membrane organization GO:0061024 292 0.029
neuron apoptotic process GO:0051402 39 0.029
covalent chromatin modification GO:0016569 254 0.029
cellular response to dna damage stimulus GO:0006974 379 0.029
negative regulation of cell death GO:0060548 345 0.029
epithelium development GO:0060429 227 0.028
cytoplasmic transport GO:0016482 379 0.028
regeneration GO:0031099 4 0.027
cellular amino acid biosynthetic process GO:0008652 30 0.027
vesicle mediated transport GO:0016192 371 0.027
growth GO:0040007 202 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
positive regulation of cellular component organization GO:0051130 376 0.026
oogenesis GO:0048477 2 0.026
associative learning GO:0008306 1 0.025
rna transport GO:0050658 39 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
protein glycosylation GO:0006486 62 0.025
macromolecule glycosylation GO:0043413 63 0.025
purine ribonucleotide biosynthetic process GO:0009152 79 0.025
segmentation GO:0035282 4 0.025
ion transmembrane transport GO:0034220 338 0.025
methylation GO:0032259 106 0.024
intracellular mrna localization GO:0008298 1 0.024
single organism cellular localization GO:1902580 332 0.024
purine ribonucleoside biosynthetic process GO:0046129 23 0.024
sex determination GO:0007530 3 0.024
protein alkylation GO:0008213 74 0.024
negative regulation of programmed cell death GO:0043069 321 0.023
ras protein signal transduction GO:0007265 73 0.023
regulation of peptidase activity GO:0052547 180 0.022
oxidation reduction process GO:0055114 396 0.022
spermatid development GO:0007286 4 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
mitotic sister chromatid segregation GO:0000070 53 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
purine containing compound catabolic process GO:0072523 411 0.022
behavioral defense response GO:0002209 0 0.022
cell activation GO:0001775 213 0.022
female gamete generation GO:0007292 2 0.022
glycoprotein biosynthetic process GO:0009101 91 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
histone lysine methylation GO:0034968 50 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
mitochondrion organization GO:0007005 156 0.021
single organism membrane organization GO:0044802 268 0.021
response to wounding GO:0009611 168 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
nuclear transport GO:0051169 179 0.021
cellular protein complex assembly GO:0043623 188 0.021
compound eye development GO:0048749 1 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
fatty acid metabolic process GO:0006631 115 0.020
purine nucleoside monophosphate catabolic process GO:0009128 158 0.020
cell division GO:0051301 168 0.020
protein modification by small protein conjugation GO:0032446 342 0.020
protein processing GO:0016485 226 0.019
nucleoside monophosphate metabolic process GO:0009123 191 0.019
spermatid differentiation GO:0048515 4 0.019
determination of adult lifespan GO:0008340 2 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.019
cell type specific apoptotic process GO:0097285 125 0.019
oocyte differentiation GO:0009994 2 0.019
immune response GO:0006955 307 0.019
neurogenesis GO:0022008 169 0.019
regulation of neuron death GO:1901214 56 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
regulation of cellular component movement GO:0051270 334 0.018
actin filament based process GO:0030029 224 0.018
establishment of rna localization GO:0051236 39 0.018
neurological system process GO:0050877 163 0.018
organelle fission GO:0048285 149 0.018
multi organism cellular process GO:0044764 156 0.018
apoptotic signaling pathway GO:0097190 268 0.018
multicellular organismal aging GO:0010259 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
rna localization GO:0006403 41 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
developmental growth GO:0048589 48 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
cellular lipid metabolic process GO:0044255 303 0.017
regulation of cell differentiation GO:0045595 393 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
negative regulation of organelle organization GO:0010639 126 0.017
response to bacterium GO:0009617 144 0.017
anterior posterior axis specification embryo GO:0008595 2 0.016
behavior GO:0007610 112 0.016
regulation of cell division GO:0051302 116 0.016
response to abiotic stimulus GO:0009628 336 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.016
engulfment of apoptotic cell GO:0043652 2 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
regulation of dna metabolic process GO:0051052 153 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
peripheral nervous system development GO:0007422 2 0.015
anion transport GO:0006820 161 0.015
regulation of membrane potential GO:0042391 95 0.015
positive regulation of growth GO:0045927 58 0.015
protein catabolic process GO:0030163 325 0.015
lymphocyte activation GO:0046649 133 0.015
negative regulation of cell cycle GO:0045786 193 0.015
reproduction GO:0000003 63 0.015
regulation of cell migration GO:0030334 289 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
transmembrane transport GO:0055085 399 0.015
cell morphogenesis involved in differentiation GO:0000904 144 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
reproductive process GO:0022414 106 0.014
memory GO:0007613 3 0.014
meiotic chromosome segregation GO:0045132 4 0.014
cell growth GO:0016049 160 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
regulation of meiosis GO:0040020 3 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
response to growth factor GO:0070848 205 0.014
nucleus organization GO:0006997 28 0.014
neuron death GO:0070997 65 0.014
sulfur compound metabolic process GO:0006790 101 0.014
metal ion transport GO:0030001 272 0.014
response to drug GO:0042493 81 0.014
actin filament based movement GO:0030048 17 0.014
neuron projection morphogenesis GO:0048812 50 0.014
developmental process involved in reproduction GO:0003006 66 0.014
histone modification GO:0016570 251 0.014
establishment of organelle localization GO:0051656 59 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
hindbrain development GO:0030902 3 0.014
signal transduction by p53 class mediator GO:0072331 72 0.014
synaptic transmission GO:0007268 61 0.013
dna conformation change GO:0071103 113 0.013
chemotaxis GO:0006935 157 0.013
response to inorganic substance GO:0010035 127 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
spindle organization GO:0007051 53 0.013
regulation of nervous system development GO:0051960 88 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
regulation of transferase activity GO:0051338 355 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
regulation of proteolysis GO:0030162 293 0.013
cell cycle phase transition GO:0044770 173 0.013
organic acid biosynthetic process GO:0016053 97 0.013
leukocyte activation GO:0045321 164 0.013
organelle fusion GO:0048284 36 0.013
response to nitrogen compound GO:1901698 184 0.013
anterior posterior axis specification GO:0009948 2 0.013
regulation of cellular response to stress GO:0080135 244 0.013
regulation of neuron apoptotic process GO:0043523 35 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
regulation of protein localization GO:0032880 296 0.013
regulation of response to external stimulus GO:0032101 222 0.013
nucleobase containing compound transport GO:0015931 51 0.012
regulation of multi organism process GO:0043900 157 0.012
rna export from nucleus GO:0006405 33 0.012
head development GO:0060322 108 0.012
single organism reproductive process GO:0044702 98 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
mrna transport GO:0051028 30 0.012
positive regulation of immune system process GO:0002684 283 0.012
protein localization to organelle GO:0033365 280 0.012
protein maturation GO:0051604 233 0.012
ameboidal type cell migration GO:0001667 135 0.012
mrna metabolic process GO:0016071 175 0.012
positive regulation of transport GO:0051050 336 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
gmp metabolic process GO:0046037 4 0.012
purine ribonucleoside metabolic process GO:0046128 437 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
mitotic nuclear division GO:0007067 119 0.011
dna repair GO:0006281 198 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
positive regulation of catabolic process GO:0009896 310 0.011
cation transmembrane transport GO:0098655 238 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
blastoderm segmentation GO:0007350 2 0.011
blastocyst development GO:0001824 3 0.011
regulation of nuclear division GO:0051783 65 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
nucleoside biosynthetic process GO:0009163 26 0.011
protein localization to nucleus GO:0034504 136 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of protein catabolic process GO:0042176 155 0.011
sulfur compound biosynthetic process GO:0044272 38 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.011
lipid metabolic process GO:0006629 381 0.011
protein tetramerization GO:0051262 47 0.011
protein secretion GO:0009306 98 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
interspecies interaction between organisms GO:0044419 156 0.011
purine containing compound salvage GO:0043101 2 0.011
cellular potassium ion transport GO:0071804 60 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
regulation of secretion GO:0051046 194 0.011
endosomal transport GO:0016197 129 0.010
negative regulation of mitotic cell cycle GO:0045930 102 0.010
action potential GO:0001508 34 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
organophosphate catabolic process GO:0046434 430 0.010
blood vessel development GO:0001568 172 0.010
small molecule biosynthetic process GO:0044283 157 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
cellular protein catabolic process GO:0044257 261 0.010
taxis GO:0042330 157 0.010
positive regulation of protein transport GO:0051222 135 0.010
embryo development ending in birth or egg hatching GO:0009792 34 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010

METAP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.058
inherited metabolic disorder DOID:655 242 0.047
central nervous system disease DOID:331 186 0.029
neurodegenerative disease DOID:1289 102 0.029
nervous system disease DOID:863 431 0.029
carbohydrate metabolic disorder DOID:2978 55 0.014
amino acid metabolic disorder DOID:9252 50 0.012