Homo sapiens

240 known processes

SIRT2

sirtuin 2

(Aliases: FLJ37491,SIR2,SIR2L2,FLJ35621,SIR2L)

SIRT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g2 dna damage checkpoint GO:0031572 26 0.756
regulation of ligase activity GO:0051340 29 0.624
regulation of ubiquitin protein transferase activity GO:0051438 28 0.505
protein ubiquitination GO:0016567 314 0.468
protein modification by small protein conjugation GO:0032446 342 0.455
positive regulation of ligase activity GO:0051351 19 0.448
regulation of protein ubiquitination GO:0031396 95 0.426
chromosome segregation GO:0007059 114 0.411
Mouse
cilium assembly GO:0042384 63 0.394
regulation of mitosis GO:0007088 63 0.348
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.316
cilium organization GO:0044782 68 0.274
cilium morphogenesis GO:0060271 75 0.240
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.227
positive regulation of transferase activity GO:0051347 227 0.222
positive regulation of protein ubiquitination GO:0031398 53 0.210
modification dependent macromolecule catabolic process GO:0043632 212 0.206
organelle assembly GO:0070925 176 0.200
modification dependent protein catabolic process GO:0019941 209 0.198
cellular response to dna damage stimulus GO:0006974 379 0.191
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.184
cell division GO:0051301 168 0.180
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.179
regulation of proteolysis GO:0030162 293 0.175
regulation of cellular ketone metabolic process GO:0010565 50 0.173
cellular response to oxygen containing compound GO:1901701 276 0.171
Mouse
regulation of transferase activity GO:0051338 355 0.166
dna damage checkpoint GO:0000077 68 0.158
organelle fission GO:0048285 149 0.152
Mouse
regulation of meiotic cell cycle GO:0051445 4 0.145
Mouse
cellular ketone metabolic process GO:0042180 80 0.127
cell projection organization GO:0030030 252 0.126
oxidation reduction process GO:0055114 396 0.126
protein complex disassembly GO:0043241 52 0.126
lens development in camera type eye GO:0002088 2 0.123
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.123
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.122
cell morphogenesis GO:0000902 296 0.122
cell projection assembly GO:0030031 126 0.122
regulation of meiosis GO:0040020 3 0.116
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.114
mitotic nuclear division GO:0007067 119 0.113
cell cycle checkpoint GO:0000075 117 0.107
dephosphorylation GO:0016311 209 0.105
cellular protein catabolic process GO:0044257 261 0.103
dna integrity checkpoint GO:0031570 71 0.102
histone modification GO:0016570 251 0.099
positive regulation of cell division GO:0051781 59 0.097
Mouse
regulation of mitotic cell cycle GO:0007346 189 0.096
protein catabolic process GO:0030163 325 0.094
post embryonic development GO:0009791 2 0.089
meiosis i GO:0007127 4 0.088
positive regulation of cellular component organization GO:0051130 376 0.087
Mouse
cellular response to external stimulus GO:0071496 111 0.086
Mouse
cellular component disassembly GO:0022411 92 0.086
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.086
anatomical structure formation involved in morphogenesis GO:0048646 284 0.085
regulation of cell cycle GO:0051726 393 0.080
meiotic chromosome segregation GO:0045132 4 0.078
epithelium development GO:0060429 227 0.077
cellular component morphogenesis GO:0032989 314 0.077
peptidyl tyrosine dephosphorylation GO:0035335 36 0.077
negative regulation of developmental process GO:0051093 247 0.073
protein dephosphorylation GO:0006470 81 0.072
multicellular organismal aging GO:0010259 3 0.072
regulation of nuclear division GO:0051783 65 0.070
Mouse
regeneration GO:0031099 4 0.070
positive regulation of chromosome segregation GO:0051984 9 0.070
Mouse
macromolecular complex disassembly GO:0032984 60 0.069
single organism carbohydrate metabolic process GO:0044723 193 0.068
regulation of cell differentiation GO:0045595 393 0.067
Mouse Rat
chromatin organization GO:0006325 351 0.067
regulation of cellular amino acid metabolic process GO:0006521 6 0.066
mitotic cell cycle process GO:1903047 286 0.066
epithelial cell differentiation GO:0030855 141 0.065
mitotic cell cycle GO:0000278 326 0.065
apoptotic signaling pathway GO:0097190 268 0.064
proteasomal protein catabolic process GO:0010498 176 0.063
positive regulation of cell proliferation GO:0008284 301 0.063
regulation of cellular protein catabolic process GO:1903362 96 0.062
microtubule cytoskeleton organization GO:0000226 176 0.061
Mouse
behavior GO:0007610 112 0.061
extraocular skeletal muscle development GO:0002074 1 0.060
protein maturation GO:0051604 233 0.060
amine metabolic process GO:0009308 44 0.058
positive regulation of cellular protein catabolic process GO:1903364 37 0.057
metaphase anaphase transition of cell cycle GO:0044784 21 0.057
positive regulation of cellular amine metabolic process GO:0033240 7 0.056
cellular response to nutrient levels GO:0031669 69 0.056
Mouse
system process GO:0003008 349 0.056
Mouse Rat
exit from mitosis GO:0010458 10 0.056
muscle system process GO:0003012 81 0.055
cardiovascular system development GO:0072358 262 0.054
regulation of cell division GO:0051302 116 0.053
Mouse
generation of precursor metabolites and energy GO:0006091 68 0.053
positive regulation of programmed cell death GO:0043068 249 0.053
Mouse
cyclin catabolic process GO:0008054 6 0.052
peptidyl serine phosphorylation GO:0018105 101 0.052
regulation of proteasomal protein catabolic process GO:0061136 87 0.052
locomotory behavior GO:0007626 1 0.052
positive regulation of mitosis GO:0045840 25 0.051
negative regulation of protein metabolic process GO:0051248 391 0.050
carbohydrate metabolic process GO:0005975 207 0.050
regulation of anatomical structure morphogenesis GO:0022603 286 0.049
cellular amine metabolic process GO:0044106 41 0.049
regulation of protein localization GO:0032880 296 0.048
Mouse
cellular amino acid metabolic process GO:0006520 116 0.048
protein deacylation GO:0035601 39 0.048
post embryonic organ development GO:0048569 1 0.048
immune system development GO:0002520 195 0.048
mitotic sister chromatid separation GO:0051306 18 0.047
positive regulation of organelle organization GO:0010638 195 0.047
Mouse
peptidyl lysine modification GO:0018205 144 0.047
enzyme linked receptor protein signaling pathway GO:0007167 303 0.047
cell part morphogenesis GO:0032990 137 0.047
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.047
nervous system development GO:0007399 293 0.046
cellular macromolecule catabolic process GO:0044265 380 0.046
mitotic sister chromatid segregation GO:0000070 53 0.045
response to oxygen containing compound GO:1901700 369 0.045
Mouse
peptidyl serine modification GO:0018209 106 0.045
tachykinin receptor signaling pathway GO:0007217 3 0.045
determination of adult lifespan GO:0008340 2 0.045
cellular response to parathyroid hormone stimulus GO:0071374 2 0.044
cell aging GO:0007569 52 0.043
Yeast
positive regulation of proteolysis GO:0045862 142 0.043
intracellular protein transport GO:0006886 270 0.042
regulation of cellular component biogenesis GO:0044087 281 0.042
Mouse
sister chromatid segregation GO:0000819 54 0.042
female gamete generation GO:0007292 2 0.040
Mouse
protein polyubiquitination GO:0000209 110 0.040
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 7 0.040
catecholamine secretion GO:0050432 1 0.039
cellular macromolecular complex assembly GO:0034622 324 0.038
Mouse
purine ribonucleoside metabolic process GO:0046128 437 0.038
regulation of anatomical structure size GO:0090066 101 0.038
growth GO:0040007 202 0.038
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.037
covalent chromatin modification GO:0016569 254 0.036
positive regulation of catabolic process GO:0009896 310 0.036
regulation of mitotic sister chromatid segregation GO:0033047 27 0.036
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.036
cell projection morphogenesis GO:0048858 129 0.036
myoblast fusion GO:0007520 1 0.036
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.035
macroautophagy GO:0016236 39 0.035
tissue migration GO:0090130 119 0.035
regulation of purine nucleotide metabolic process GO:1900542 264 0.035
tissue regeneration GO:0042246 3 0.035
protein processing GO:0016485 226 0.035
establishment of protein localization to organelle GO:0072594 172 0.034
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.034
programmed cell death in response to reactive oxygen species GO:0097468 4 0.033
regulation of cellular response to stress GO:0080135 244 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.033
negative regulation of cellular component organization GO:0051129 235 0.033
Mouse
circulatory system development GO:0072359 262 0.033
cellular response to starvation GO:0009267 58 0.033
Mouse
epithelium migration GO:0090132 119 0.033
response to lipid GO:0033993 206 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
activation of anaphase promoting complex activity GO:0051488 6 0.032
regulation of mitotic sister chromatid separation GO:0010965 27 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
Mouse
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.032
positive regulation of cellular component biogenesis GO:0044089 158 0.032
positive regulation of nuclear division GO:0051785 27 0.032
Mouse
cellular protein complex assembly GO:0043623 188 0.031
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
regulation of apoptotic signaling pathway GO:2001233 175 0.031
regulation of locomotion GO:0040012 329 0.031
peptidyl threonine phosphorylation GO:0018107 41 0.031
Mouse
negative regulation of phosphorus metabolic process GO:0010563 267 0.031
Mouse
response to abiotic stimulus GO:0009628 336 0.031
regulation of reactive oxygen species metabolic process GO:2000377 41 0.031
Mouse
cytoplasmic transport GO:0016482 379 0.031
regulation of cell aging GO:0090342 18 0.030
oogenesis GO:0048477 2 0.030
Mouse
negative regulation of catalytic activity GO:0043086 335 0.030
lens fiber cell differentiation GO:0070306 2 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.029
negative regulation of protein processing GO:0010955 142 0.029
regulation of growth GO:0040008 165 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
Mouse
tricarboxylic acid cycle GO:0006099 4 0.029
negative regulation of cell death GO:0060548 345 0.029
Rat
nucleoside triphosphate metabolic process GO:0009141 422 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.028
regulation of cell cycle phase transition GO:1901987 126 0.028
cell fate determination GO:0001709 3 0.028
regulation of cell cycle process GO:0010564 266 0.028
Mouse
single organism cellular localization GO:1902580 332 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.028
misfolded protein transport GO:0070843 1 0.028
nitrogen compound transport GO:0071705 191 0.027
regulation of microtubule cytoskeleton organization GO:0070507 61 0.027
Mouse
negative regulation of cell differentiation GO:0045596 171 0.027
Mouse Rat
regulation of cellular amine metabolic process GO:0033238 11 0.027
aging GO:0007568 66 0.027
Yeast
regulation of sister chromatid segregation GO:0033045 27 0.026
regulation of protein processing GO:0070613 150 0.026
small molecule biosynthetic process GO:0044283 157 0.026
response to extracellular stimulus GO:0009991 85 0.026
Mouse
negative regulation of protein maturation GO:1903318 142 0.026
negative regulation of striated muscle contraction GO:0045988 2 0.026
cellular carbohydrate metabolic process GO:0044262 84 0.026
cellular response to hormone stimulus GO:0032870 125 0.026
regulation of response to external stimulus GO:0032101 222 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
lipid biosynthetic process GO:0008610 177 0.026
organophosphate catabolic process GO:0046434 430 0.025
retina homeostasis GO:0001895 42 0.025
regulation of neural precursor cell proliferation GO:2000177 4 0.025
Rat
muscle contraction GO:0006936 73 0.025
chromatin modification GO:0016568 298 0.025
regulation of cell migration GO:0030334 289 0.025
myeloid cell differentiation GO:0030099 117 0.025
response to hormone GO:0009725 175 0.025
gtp catabolic process GO:0006184 237 0.025
lipid metabolic process GO:0006629 381 0.025
Mouse
energy derivation by oxidation of organic compounds GO:0015980 43 0.025
histone h3 acetylation GO:0043966 45 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
Mouse
positive regulation of apoptotic process GO:0043065 246 0.024
Mouse
histone acetylation GO:0016573 93 0.024
protein acylation GO:0043543 138 0.024
protein targeting GO:0006605 187 0.024
syncytium formation by plasma membrane fusion GO:0000768 2 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
positive regulation of mitotic cell cycle GO:0045931 60 0.024
regulation of microtubule based process GO:0032886 74 0.024
Mouse
response to wounding GO:0009611 168 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
sensory organ development GO:0007423 52 0.024
circulatory system process GO:0003013 113 0.023
regulation of cellular component size GO:0032535 82 0.023
positive regulation of transport GO:0051050 336 0.023
somatic muscle development GO:0007525 1 0.023
organic hydroxy compound transport GO:0015850 63 0.023
immune response GO:0006955 307 0.023
biological adhesion GO:0022610 331 0.023
histone deacetylation GO:0016575 32 0.023
negative regulation of proteolysis GO:0045861 132 0.023
nerve development GO:0021675 4 0.023
regulation of protein kinase activity GO:0045859 289 0.023
regulation of chromosome organization GO:0033044 103 0.023
macromolecule deacylation GO:0098732 41 0.023
neuromuscular junction development GO:0007528 3 0.023
response to oxidative stress GO:0006979 121 0.023
Mouse
mitotic cell cycle phase transition GO:0044772 162 0.023
response to starvation GO:0042594 59 0.023
Mouse
innate immune response GO:0045087 178 0.022
positive regulation of chromosome organization GO:2001252 41 0.022
cell morphogenesis involved in differentiation GO:0000904 144 0.022
associative learning GO:0008306 1 0.022
cell adhesion GO:0007155 325 0.022
response to nutrient levels GO:0031667 81 0.022
Mouse
nuclear division GO:0000280 128 0.022
Mouse
chemical homeostasis GO:0048878 306 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
vesicle mediated transport GO:0016192 371 0.021
citrate metabolic process GO:0006101 2 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
regulation of immune response GO:0050776 201 0.021
protein autophosphorylation GO:0046777 123 0.021
histone h4 acetylation GO:0043967 47 0.020
regulation of protein transport GO:0051223 213 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
regulation of cell morphogenesis GO:0022604 153 0.020
cell cycle phase transition GO:0044770 173 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
positive regulation of developmental process GO:0051094 314 0.020
Mouse
ameboidal type cell migration GO:0001667 135 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
compound eye development GO:0048749 1 0.020
blood vessel morphogenesis GO:0048514 162 0.020
cellular response to organic cyclic compound GO:0071407 127 0.019
Mouse
regulation of protein maturation GO:1903317 150 0.019
organelle disassembly GO:1903008 9 0.019
protein acetylation GO:0006473 116 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
regulation of cellular component movement GO:0051270 334 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
cellular response to peptide GO:1901653 59 0.019
organophosphate biosynthetic process GO:0090407 163 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
negative regulation of cell cycle GO:0045786 193 0.019
embryo development GO:0009790 123 0.019
single organism membrane organization GO:0044802 268 0.018
response to biotic stimulus GO:0009607 276 0.018
adult locomotory behavior GO:0008344 1 0.018
regulation of hydrogen peroxide mediated programmed cell death GO:1901298 4 0.018
cellular component assembly involved in morphogenesis GO:0010927 73 0.018
cellular response to misfolded protein GO:0071218 2 0.018
segmentation GO:0035282 4 0.018
mitochondrion organization GO:0007005 156 0.018
regulation of rhodopsin mediated signaling pathway GO:0022400 1 0.018
hydrogen peroxide mediated programmed cell death GO:0010421 4 0.018
response to organonitrogen compound GO:0010243 156 0.018
Mouse
ras protein signal transduction GO:0007265 73 0.018
regulation of homeostatic process GO:0032844 121 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
pharynx development GO:0060465 1 0.018
rho protein signal transduction GO:0007266 26 0.018
response to organic cyclic compound GO:0014070 204 0.018
Mouse
cellular response to organonitrogen compound GO:0071417 124 0.018
Mouse
positive regulation of amine transport GO:0051954 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
positive regulation of cell death GO:0010942 263 0.017
Mouse
tricarboxylic acid metabolic process GO:0072350 4 0.017
response to growth factor GO:0070848 205 0.017
regulation of catecholamine secretion GO:0050433 1 0.017
regulation of gene expression epigenetic GO:0040029 73 0.017
Yeast
response to inorganic substance GO:0010035 127 0.017
neuroblast proliferation GO:0007405 4 0.017
cellular polysaccharide metabolic process GO:0044264 27 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.017
limbic system development GO:0021761 3 0.017
single organism cell adhesion GO:0098602 179 0.017
oocyte differentiation GO:0009994 2 0.016
Mouse
positive regulation of secretion by cell GO:1903532 108 0.016
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.016
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.016
protein deacetylation GO:0006476 38 0.016
positive regulation of cell motility GO:2000147 177 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
regulation of ras gtpase activity GO:0032318 128 0.016
wnt signaling pathway GO:0016055 156 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
defense response GO:0006952 315 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
regulation of protein complex assembly GO:0043254 147 0.016
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.016
response to oxygen levels GO:0070482 100 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
receptor metabolic process GO:0043112 81 0.016
regulation of response to wounding GO:1903034 101 0.016
negative regulation of organelle organization GO:0010639 126 0.016
keratinization GO:0031424 2 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
protein targeting to nucleus GO:0044744 104 0.016
activation of immune response GO:0002253 114 0.016
positive regulation of cell migration GO:0030335 172 0.015
cellular response to reactive oxygen species GO:0034614 50 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.015
circadian behavior GO:0048512 2 0.015
peptidyl threonine modification GO:0018210 45 0.015
Mouse
single organism nuclear import GO:1902593 104 0.015
stress activated protein kinase signaling cascade GO:0031098 94 0.015
protein import into nucleus GO:0006606 104 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
response to parathyroid hormone GO:0071107 3 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
negative regulation of muscle contraction GO:0045932 3 0.015
regulation of peptidyl serine phosphorylation GO:0033135 50 0.015
positive regulation of immune system process GO:0002684 283 0.015
memory GO:0007613 3 0.015
response to steroid hormone GO:0048545 80 0.015
carboxylic acid biosynthetic process GO:0046394 97 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
rab protein signal transduction GO:0032482 4 0.015
cellular response to extracellular stimulus GO:0031668 72 0.014
Mouse
nuclear transport GO:0051169 179 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
maintenance of location GO:0051235 112 0.014
Mouse
response to nitrogen compound GO:1901698 184 0.014
Mouse
generation of neurons GO:0048699 152 0.014
Rat
single organism reproductive process GO:0044702 98 0.014
Mouse
regulation of amine transport GO:0051952 5 0.014
fatty acid metabolic process GO:0006631 115 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
peripheral nervous system development GO:0007422 2 0.014
Mouse Rat
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.014
protein localization to organelle GO:0033365 280 0.014
translation GO:0006412 132 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
negative regulation of the force of heart contraction by chemical signal GO:0003108 1 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
polysaccharide metabolic process GO:0005976 33 0.014
regulation of cytokine production GO:0001817 232 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
regulation of protein depolymerization GO:1901879 22 0.014
phototransduction visible light GO:0007603 2 0.014
ion homeostasis GO:0050801 230 0.014
cell growth GO:0016049 160 0.014
actin filament based process GO:0030029 224 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.014
t cell differentiation in thymus GO:0033077 4 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
blood circulation GO:0008015 113 0.014
wound healing GO:0042060 115 0.014
hemopoiesis GO:0030097 180 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
positive regulation of immune response GO:0050778 159 0.014
immune response regulating signaling pathway GO:0002764 97 0.014
regulation of intracellular transport GO:0032386 195 0.014
negative regulation of catabolic process GO:0009895 104 0.014
monosaccharide metabolic process GO:0005996 74 0.014
tissue homeostasis GO:0001894 63 0.014
regulation of heart contraction GO:0008016 50 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
alcohol metabolic process GO:0006066 114 0.013
response to peptide GO:1901652 65 0.013
negative regulation of cell growth GO:0030308 83 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
secretion by cell GO:0032940 226 0.013
cellular lipid metabolic process GO:0044255 303 0.013
Mouse
epithelial cell migration GO:0010631 119 0.013
regulation of dephosphorylation GO:0035303 96 0.013
internal protein amino acid acetylation GO:0006475 101 0.013
response to dexamethasone GO:0071548 1 0.013
carbohydrate biosynthetic process GO:0016051 42 0.013
rhodopsin mediated signaling pathway GO:0016056 1 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
Mouse
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
organelle localization GO:0051640 84 0.013
anatomical structure homeostasis GO:0060249 100 0.013
secretion GO:0046903 254 0.013
eye development GO:0001654 42 0.013
positive regulation of protein complex assembly GO:0031334 86 0.013
neuron differentiation GO:0030182 138 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
rhythmic behavior GO:0007622 2 0.013
mrna metabolic process GO:0016071 175 0.013
organic acid biosynthetic process GO:0016053 97 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
rna splicing GO:0008380 131 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
protein depolymerization GO:0051261 30 0.013
cellular response to oxygen levels GO:0071453 55 0.013
membrane organization GO:0061024 292 0.012
regulation of mapk cascade GO:0043408 262 0.012
cellular response to lipid GO:0071396 127 0.012
patterning of blood vessels GO:0001569 2 0.012
regulation of cell adhesion GO:0030155 166 0.012
negative regulation of protein complex disassembly GO:0043242 20 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
positive regulation of neural precursor cell proliferation GO:2000179 2 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
heart development GO:0007507 95 0.012
rna processing GO:0006396 255 0.012
spermatid differentiation GO:0048515 4 0.012
somatic stem cell maintenance GO:0035019 4 0.012
glycerolipid metabolic process GO:0046486 107 0.012
cellular response to nitrogen compound GO:1901699 144 0.012
Mouse
meiotic cell cycle process GO:1903046 8 0.012
regulation of feeding behavior GO:0060259 3 0.012
neurotransmitter secretion GO:0007269 4 0.012
regulation of cell activation GO:0050865 125 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
head development GO:0060322 108 0.012
negative regulation of wnt signaling pathway GO:0030178 69 0.012
protein import GO:0017038 130 0.012
nucleoside catabolic process GO:0009164 408 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
regulation of body fluid levels GO:0050878 99 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
cytokinesis GO:0000910 96 0.012
response to corticosteroid GO:0031960 15 0.012
regulation of phosphatase activity GO:0010921 81 0.012
regulation of muscle system process GO:0090257 53 0.012
positive regulation of intracellular transport GO:0032388 104 0.012

SIRT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.038
nervous system disease DOID:863 431 0.038
disease of metabolism DOID:0014667 295 0.037
inherited metabolic disorder DOID:655 242 0.036
central nervous system disease DOID:331 186 0.031
disease of cellular proliferation DOID:14566 174 0.025
eye and adnexa disease DOID:1492 150 0.025
cancer DOID:162 167 0.023
organ system cancer DOID:0050686 164 0.023
eye disease DOID:5614 149 0.022
musculoskeletal system disease DOID:17 223 0.020
immune system disease DOID:2914 155 0.018
neurodegenerative disease DOID:1289 102 0.015
muscular disease DOID:0080000 114 0.013
muscle tissue disease DOID:66 113 0.013
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.013