Homo sapiens

27 known processes

FYCO1

FYVE and coiled-coil domain containing 1

(Aliases: MGC126519,RUFY3,MGC126517,DKFZp779K1152,FLJ13335,ZFYVE7)

FYCO1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism cellular localization GO:1902580 332 0.229
response to external biotic stimulus GO:0043207 261 0.115
cytoplasmic transport GO:0016482 379 0.107
cellular protein catabolic process GO:0044257 261 0.100
growth GO:0040007 202 0.096
proteasomal protein catabolic process GO:0010498 176 0.095
purine ribonucleotide catabolic process GO:0009154 404 0.082
microtubule based process GO:0007017 210 0.082
tube development GO:0035295 125 0.081
negative regulation of cellular protein metabolic process GO:0032269 353 0.075
chromatin organization GO:0006325 351 0.073
determination of adult lifespan GO:0008340 2 0.069
response to other organism GO:0051707 261 0.068
cell growth GO:0016049 160 0.068
cell division GO:0051301 168 0.067
response to biotic stimulus GO:0009607 276 0.065
cellular response to external stimulus GO:0071496 111 0.064
negative regulation of cell death GO:0060548 345 0.061
microtubule based movement GO:0007018 32 0.061
locomotory behavior GO:0007626 1 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.057
system process GO:0003008 349 0.057
regulation of cellular amine metabolic process GO:0033238 11 0.055
mitotic cell cycle process GO:1903047 286 0.055
organelle assembly GO:0070925 176 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
mitotic cell cycle GO:0000278 326 0.052
protein catabolic process GO:0030163 325 0.051
nucleoside phosphate catabolic process GO:1901292 412 0.049
intracellular protein transport GO:0006886 270 0.048
regulation of cell growth GO:0001558 135 0.048
microtubule cytoskeleton organization GO:0000226 176 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.046
cellular response to nutrient levels GO:0031669 69 0.044
cell morphogenesis GO:0000902 296 0.043
negative regulation of protein metabolic process GO:0051248 391 0.043
cellular response to starvation GO:0009267 58 0.042
multicellular organismal aging GO:0010259 3 0.041
midgut development GO:0007494 1 0.041
negative regulation of programmed cell death GO:0043069 321 0.040
protein maturation GO:0051604 233 0.040
nucleotide catabolic process GO:0009166 408 0.039
protein modification by small protein conjugation GO:0032446 342 0.039
positive regulation of synaptic transmission GO:0050806 4 0.039
amine metabolic process GO:0009308 44 0.038
purine nucleoside triphosphate metabolic process GO:0009144 412 0.038
chromatin modification GO:0016568 298 0.038
segmentation GO:0035282 4 0.038
regulation of cellular response to stress GO:0080135 244 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
cellular macromolecule catabolic process GO:0044265 380 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
positive regulation of hydrolase activity GO:0051345 331 0.037
actin filament based process GO:0030029 224 0.036
cellular response to dna damage stimulus GO:0006974 379 0.036
negative regulation of protein processing GO:0010955 142 0.035
regulation of transferase activity GO:0051338 355 0.035
positive regulation of cell death GO:0010942 263 0.034
defense response GO:0006952 315 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
negative regulation of proteolysis GO:0045861 132 0.034
response to oxygen containing compound GO:1901700 369 0.034
vesicle mediated transport GO:0016192 371 0.034
single organism membrane organization GO:0044802 268 0.034
cell cell signaling GO:0007267 155 0.033
protein ubiquitination GO:0016567 314 0.033
regulation of protein complex assembly GO:0043254 147 0.033
regulation of proteolysis GO:0030162 293 0.032
neuromuscular junction development GO:0007528 3 0.032
nucleoside catabolic process GO:0009164 408 0.031
cellular amine metabolic process GO:0044106 41 0.031
response to nutrient levels GO:0031667 81 0.031
guanosine containing compound metabolic process GO:1901068 244 0.031
protein localization to organelle GO:0033365 280 0.031
vacuole organization GO:0007033 44 0.031
response to abiotic stimulus GO:0009628 336 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.030
regulation of purine nucleotide catabolic process GO:0033121 205 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
establishment of organelle localization GO:0051656 59 0.030
histone modification GO:0016570 251 0.030
metal ion transport GO:0030001 272 0.029
purine containing compound catabolic process GO:0072523 411 0.029
cellular ketone metabolic process GO:0042180 80 0.029
organophosphate catabolic process GO:0046434 430 0.029
regulation of protein catabolic process GO:0042176 155 0.028
positive regulation of transport GO:0051050 336 0.028
digestive system development GO:0055123 75 0.028
defense response to other organism GO:0098542 129 0.028
autophagic vacuole assembly GO:0000045 19 0.028
regulation of protein maturation GO:1903317 150 0.027
golgi vesicle transport GO:0048193 80 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
regulation of kinase activity GO:0043549 314 0.026
organelle localization GO:0051640 84 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
cellular response to extracellular stimulus GO:0031668 72 0.026
nervous system development GO:0007399 293 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
protein processing GO:0016485 226 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
ras protein signal transduction GO:0007265 73 0.025
epidermis morphogenesis GO:0048730 3 0.025
ubiquitin dependent protein catabolic process GO:0006511 206 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
positive regulation of phosphorylation GO:0042327 394 0.024
establishment of protein localization to organelle GO:0072594 172 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.024
regulation of cell migration GO:0030334 289 0.024
post embryonic development GO:0009791 2 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.023
regulation of protein kinase activity GO:0045859 289 0.023
regulation of membrane potential GO:0042391 95 0.023
digestive tract development GO:0048565 75 0.023
compound eye development GO:0048749 1 0.023
negative regulation of organelle organization GO:0010639 126 0.023
monovalent inorganic cation transport GO:0015672 128 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
response to extracellular stimulus GO:0009991 85 0.022
negative regulation of protein maturation GO:1903318 142 0.022
regulation of protein processing GO:0070613 150 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
memory GO:0007613 3 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
adult locomotory behavior GO:0008344 1 0.022
mitochondrion organization GO:0007005 156 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
membrane organization GO:0061024 292 0.021
response to inorganic substance GO:0010035 127 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.020
transmembrane transport GO:0055085 399 0.020
cellular component disassembly GO:0022411 92 0.020
cell part morphogenesis GO:0032990 137 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
inner ear morphogenesis GO:0042472 4 0.020
establishment of cell polarity GO:0030010 22 0.020
regulation of cell cycle GO:0051726 393 0.020
maintenance of location GO:0051235 112 0.020
autophagy GO:0006914 88 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
regulation of cell cycle process GO:0010564 266 0.020
protein targeting GO:0006605 187 0.020
immune system development GO:0002520 195 0.020
small gtpase mediated signal transduction GO:0007264 78 0.020
organelle fission GO:0048285 149 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
nuclear transport GO:0051169 179 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.019
microtubule organizing center organization GO:0031023 62 0.019
covalent chromatin modification GO:0016569 254 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.019
nucleoside triphosphate catabolic process GO:0009143 394 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
multi organism cellular process GO:0044764 156 0.019
cardiovascular system development GO:0072358 262 0.018
negative regulation of transferase activity GO:0051348 124 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
response to fungus GO:0009620 4 0.018
negative regulation of binding GO:0051100 57 0.018
negative regulation of catabolic process GO:0009895 104 0.018
gtp catabolic process GO:0006184 237 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
regulation of locomotion GO:0040012 329 0.018
regulation of protein transport GO:0051223 213 0.018
negative regulation of cellular protein catabolic process GO:1903363 38 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
blastoderm segmentation GO:0007350 2 0.018
regulation of protein localization GO:0032880 296 0.018
cytokine production GO:0001816 247 0.018
negative regulation of cellular catabolic process GO:0031330 83 0.018
nuclear migration GO:0007097 1 0.018
endosomal transport GO:0016197 129 0.018
regulation of cellular component movement GO:0051270 334 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
regulation of growth GO:0040008 165 0.018
oogenesis GO:0048477 2 0.017
immune response GO:0006955 307 0.017
cellular component morphogenesis GO:0032989 314 0.017
positive regulation of catabolic process GO:0009896 310 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
oxidation reduction process GO:0055114 396 0.017
secretion by cell GO:0032940 226 0.017
lipid metabolic process GO:0006629 381 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
negative regulation of kinase activity GO:0033673 106 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
cellular lipid metabolic process GO:0044255 303 0.017
generation of neurons GO:0048699 152 0.017
gtp metabolic process GO:0046039 239 0.016
macroautophagy GO:0016236 39 0.016
heart process GO:0003015 62 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
response to decreased oxygen levels GO:0036293 96 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of cell differentiation GO:0045595 393 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
hindbrain development GO:0030902 3 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
cell projection morphogenesis GO:0048858 129 0.016
metencephalon development GO:0022037 2 0.015
positive regulation of developmental process GO:0051094 314 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
protein targeting to nucleus GO:0044744 104 0.015
peptidyl serine modification GO:0018209 106 0.015
regulation of intracellular transport GO:0032386 195 0.015
regulation of gtpase activity GO:0043087 180 0.015
immune effector process GO:0002252 159 0.015
protein methylation GO:0006479 74 0.015
dna conformation change GO:0071103 113 0.015
sodium ion transport GO:0006814 61 0.015
peripheral nervous system development GO:0007422 2 0.015
mitotic nuclear division GO:0007067 119 0.015
embryo development GO:0009790 123 0.015
defense response to bacterium GO:0042742 63 0.015
tripartite regional subdivision GO:0007351 2 0.015
methylation GO:0032259 106 0.015
secretion GO:0046903 254 0.015
establishment of nucleus localization GO:0040023 1 0.015
copii vesicle coating GO:0048208 2 0.015
nuclear division GO:0000280 128 0.015
female gamete generation GO:0007292 2 0.015
positive regulation of axon extension GO:0045773 4 0.015
positive regulation of secretion GO:0051047 116 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
cation transport GO:0006812 331 0.014
positive regulation of hormone biosynthetic process GO:0046886 4 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
rna interference GO:0016246 4 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
muscle structure development GO:0061061 98 0.014
negative regulation of protein catabolic process GO:0042177 59 0.014
spindle organization GO:0007051 53 0.014
negative regulation of cell cycle GO:0045786 193 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
response to organic cyclic compound GO:0014070 204 0.014
negative regulation of protein modification process GO:0031400 200 0.014
translation GO:0006412 132 0.014
cell projection organization GO:0030030 252 0.014
regulation of anatomical structure size GO:0090066 101 0.014
lipoprotein metabolic process GO:0042157 42 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
muscle cell differentiation GO:0042692 63 0.013
anterior posterior axis specification GO:0009948 2 0.013
response to bacterium GO:0009617 144 0.013
protein oligomerization GO:0051259 173 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
negative regulation of developmental process GO:0051093 247 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
regulation of mitochondrion organization GO:0010821 54 0.013
defense response to fungus GO:0050832 4 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
innate immune response GO:0045087 178 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
post golgi vesicle mediated transport GO:0006892 36 0.013
protein polymerization GO:0051258 71 0.013
chromosome segregation GO:0007059 114 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of binding GO:0051098 111 0.013
protein localization to membrane GO:0072657 160 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
regulation of protein binding GO:0043393 66 0.013
er to golgi vesicle mediated transport GO:0006888 19 0.013
positive regulation of cell motility GO:2000147 177 0.013
vesicle targeting rough er to cis golgi GO:0048207 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
long term memory GO:0007616 2 0.013
rab protein signal transduction GO:0032482 4 0.013
tube morphogenesis GO:0035239 95 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
fatty acid metabolic process GO:0006631 115 0.013
protein secretion GO:0009306 98 0.013
cell cycle checkpoint GO:0000075 117 0.013
regulation of defense response GO:0031347 154 0.012
cellular response to decreased oxygen levels GO:0036294 51 0.012
hair cell differentiation GO:0035315 2 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
establishment of planar polarity GO:0001736 3 0.012
hemopoiesis GO:0030097 180 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
negative regulation of cell growth GO:0030308 83 0.012
histone methylation GO:0016571 60 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
myeloid cell differentiation GO:0030099 117 0.012
regulation of protein secretion GO:0050708 86 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.012
regulation of autophagy GO:0010506 52 0.012
muscle tissue development GO:0060537 62 0.012
regulation of actin filament polymerization GO:0030833 50 0.012
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.012
behavior GO:0007610 112 0.012
mapk cascade GO:0000165 288 0.012
dna repair GO:0006281 198 0.012
developmental programmed cell death GO:0010623 3 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
limbic system development GO:0021761 3 0.012
protein lipidation GO:0006497 33 0.012
cerebellum development GO:0021549 2 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
actin filament organization GO:0007015 128 0.012
negative regulation of protein transport GO:0051224 75 0.012
regulation of mapk cascade GO:0043408 262 0.012
positive regulation of transferase activity GO:0051347 227 0.012
positive regulation of kinase activity GO:0033674 204 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
regulation of cell motility GO:2000145 299 0.012
regulation of cytokine production GO:0001817 232 0.012
protein acylation GO:0043543 138 0.012
nucleus localization GO:0051647 1 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
regulation of dna repair GO:0006282 47 0.012
regulation of chromosome organization GO:0033044 103 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
viral process GO:0016032 146 0.012
regulation of peptidase activity GO:0052547 180 0.011
nitrogen compound transport GO:0071705 191 0.011
interspecies interaction between organisms GO:0044419 156 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of secretion GO:0051046 194 0.011
tube closure GO:0060606 3 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
regulation of protein polymerization GO:0032271 63 0.011
sequestering of calcium ion GO:0051208 17 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
rho protein signal transduction GO:0007266 26 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regeneration GO:0031099 4 0.011
atp metabolic process GO:0046034 176 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
somatic stem cell division GO:0048103 1 0.011
regulation of stress activated mapk cascade GO:0032872 84 0.011
positive regulation of binding GO:0051099 45 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
release of cytochrome c from mitochondria GO:0001836 35 0.011
regulation of chromatin organization GO:1902275 56 0.011
vasodilation GO:0042311 4 0.011
regulation of synaptic transmission dopaminergic GO:0032225 4 0.011
motor neuron axon guidance GO:0008045 2 0.011
cellular response to hypoxia GO:0071456 51 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
myosin filament assembly GO:0031034 2 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
negative regulation of dna metabolic process GO:0051053 57 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
regulation of ion transport GO:0043269 189 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
plasma membrane organization GO:0007009 115 0.011
protein k33 linked ubiquitination GO:1990390 1 0.011
epithelium development GO:0060429 227 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
lipoprotein biosynthetic process GO:0042158 33 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
neurogenesis GO:0022008 169 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
positive regulation of interleukin 5 production GO:0032754 3 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
protein import GO:0017038 130 0.010
positive regulation of peptidase activity GO:0010952 88 0.010
somatic muscle development GO:0007525 1 0.010
negative regulation of immune system process GO:0002683 136 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
erythrocyte development GO:0048821 3 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
negative regulation of growth GO:0045926 97 0.010
cell cycle arrest GO:0007050 71 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
rhythmic behavior GO:0007622 2 0.010
small molecule catabolic process GO:0044282 92 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010
dna packaging GO:0006323 77 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.010
neuron differentiation GO:0030182 138 0.010
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
retrograde transport endosome to golgi GO:0042147 45 0.010
response to lipid GO:0033993 206 0.010
positive regulation of ras gtpase activity GO:0032320 117 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
macromolecular complex disassembly GO:0032984 60 0.010
neural tube closure GO:0001843 3 0.010
stem cell division GO:0017145 2 0.010
regulation of cell development GO:0060284 161 0.010
embryonic hemopoiesis GO:0035162 4 0.010
regulation of actin filament based process GO:0032970 141 0.010
apoptotic signaling pathway GO:0097190 268 0.010
protein dephosphorylation GO:0006470 81 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
catecholamine secretion GO:0050432 1 0.010
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.010
regulation of translation GO:0006417 89 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.010
cellular lipid catabolic process GO:0044242 65 0.010

FYCO1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 106 0.134
musculoskeletal system disease DOID:17 223 0.044
disease of metabolism DOID:0014667 295 0.033
muscular disease DOID:0080000 114 0.027
muscle tissue disease DOID:66 113 0.026
connective tissue disease DOID:65 109 0.023
myopathy DOID:423 104 0.022
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
congenital muscular dystrophy DOID:0050557 22 0.021
muscular dystrophy DOID:9884 51 0.021
inherited metabolic disorder DOID:655 242 0.019
central nervous system disease DOID:331 186 0.017
eye and adnexa disease DOID:1492 150 0.016
emery dreifuss muscular dystrophy DOID:11726 6 0.016
heart disease DOID:114 68 0.015
retinal disease DOID:5679 118 0.015
eye disease DOID:5614 149 0.015
immune system disease DOID:2914 155 0.013
neuropathy DOID:870 52 0.013
bone disease DOID:0080001 88 0.012
cardiomyopathy DOID:0050700 50 0.011
acquired metabolic disease DOID:0060158 58 0.011
neurodegenerative disease DOID:1289 102 0.011
retinal degeneration DOID:8466 89 0.011
dilated cardiomyopathy DOID:12930 32 0.011
intrinsic cardiomyopathy DOID:0060036 50 0.011
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010