Homo sapiens

23 known processes

MLKL

mixed lineage kinase domain-like

(Aliases: FLJ34389)

MLKL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic transport GO:0016482 379 0.223
cellular amine metabolic process GO:0044106 41 0.175
cellular ketone metabolic process GO:0042180 80 0.142
post embryonic development GO:0009791 2 0.126
anion transport GO:0006820 161 0.122
immune response GO:0006955 307 0.121
regulation of cellular amine metabolic process GO:0033238 11 0.114
regulation of cellular ketone metabolic process GO:0010565 50 0.108
viral life cycle GO:0019058 132 0.104
positive regulation of cellular amine metabolic process GO:0033240 7 0.100
nucleocytoplasmic transport GO:0006913 176 0.099
regulation of cellular amino acid metabolic process GO:0006521 6 0.098
nitrogen compound transport GO:0071705 191 0.097
protein catabolic process GO:0030163 325 0.095
positive regulation of immune system process GO:0002684 283 0.085
cellular amino acid metabolic process GO:0006520 116 0.085
innate immune response GO:0045087 178 0.084
multi organism cellular process GO:0044764 156 0.078
multicellular organismal aging GO:0010259 3 0.077
amine metabolic process GO:0009308 44 0.076
determination of adult lifespan GO:0008340 2 0.072
leukocyte migration GO:0050900 107 0.068
protein autophosphorylation GO:0046777 123 0.067
regulation of cell motility GO:2000145 299 0.067
regulation of cellular component movement GO:0051270 334 0.063
regulation of cell migration GO:0030334 289 0.063
nuclear transport GO:0051169 179 0.062
ribonucleoside triphosphate catabolic process GO:0009203 391 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
positive regulation of phosphorylation GO:0042327 394 0.060
viral process GO:0016032 146 0.060
cellular protein catabolic process GO:0044257 261 0.058
single organism cellular localization GO:1902580 332 0.057
cytokine production GO:0001816 247 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.055
purine containing compound catabolic process GO:0072523 411 0.054
nucleobase containing compound transport GO:0015931 51 0.054
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.053
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.053
regulation of cytokine production GO:0001817 232 0.052
interspecies interaction between organisms GO:0044419 156 0.052
immune effector process GO:0002252 159 0.052
female gamete generation GO:0007292 2 0.051
positive regulation of protein phosphorylation GO:0001934 313 0.050
cellular macromolecule catabolic process GO:0044265 380 0.050
cellular component morphogenesis GO:0032989 314 0.050
leukocyte activation GO:0045321 164 0.050
apoptotic signaling pathway GO:0097190 268 0.049
cellular response to dna damage stimulus GO:0006974 379 0.049
response to cytokine GO:0034097 232 0.048
i kappab kinase nf kappab signaling GO:0007249 166 0.048
regulation of locomotion GO:0040012 329 0.047
regulation of proteolysis GO:0030162 293 0.047
cell projection organization GO:0030030 252 0.047
positive regulation of innate immune response GO:0045089 79 0.047
regulation of transferase activity GO:0051338 355 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.047
activation of immune response GO:0002253 114 0.046
response to oxygen containing compound GO:1901700 369 0.045
positive regulation of transport GO:0051050 336 0.045
defense response GO:0006952 315 0.044
purine ribonucleoside catabolic process GO:0046130 398 0.043
oogenesis GO:0048477 2 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
regulation of protein localization GO:0032880 296 0.043
cell activation GO:0001775 213 0.043
regulation of kinase activity GO:0043549 314 0.043
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.042
regulation of innate immune response GO:0045088 97 0.042
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.042
regulation of establishment of protein localization GO:0070201 242 0.042
regulation of cell cycle process GO:0010564 266 0.041
positive regulation of immune response GO:0050778 159 0.041
cell morphogenesis GO:0000902 296 0.041
carbohydrate derivative biosynthetic process GO:1901137 207 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
biological adhesion GO:0022610 331 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
protein oligomerization GO:0051259 173 0.040
regulation of immune response GO:0050776 201 0.040
transmembrane transport GO:0055085 399 0.039
cell adhesion GO:0007155 325 0.039
system process GO:0003008 349 0.038
regulation of lymphocyte activation GO:0051249 103 0.038
regulation of leukocyte activation GO:0002694 115 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
rhythmic behavior GO:0007622 2 0.037
regulation of defense response GO:0031347 154 0.037
cell development GO:0048468 328 0.037
organophosphate catabolic process GO:0046434 430 0.037
response to organonitrogen compound GO:0010243 156 0.037
organonitrogen compound biosynthetic process GO:1901566 200 0.036
organic anion transport GO:0015711 103 0.036
nucleoside triphosphate metabolic process GO:0009141 422 0.036
ribonucleotide catabolic process GO:0009261 405 0.035
purine ribonucleotide catabolic process GO:0009154 404 0.035
anatomical structure formation involved in morphogenesis GO:0048646 284 0.035
purine nucleotide catabolic process GO:0006195 405 0.035
nucleoside catabolic process GO:0009164 408 0.035
lipid transport GO:0006869 90 0.035
regulation of leukocyte migration GO:0002685 63 0.035
positive regulation of programmed cell death GO:0043068 249 0.034
regulation of response to external stimulus GO:0032101 222 0.034
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.033
positive regulation of kinase activity GO:0033674 204 0.032
inorganic ion transmembrane transport GO:0098660 231 0.032
positive regulation of apoptotic process GO:0043065 246 0.032
carbohydrate metabolic process GO:0005975 207 0.032
immune response activating signal transduction GO:0002757 90 0.031
defense response to other organism GO:0098542 129 0.031
regulation of protein transport GO:0051223 213 0.031
regulation of protein kinase activity GO:0045859 289 0.031
nucleic acid transport GO:0050657 39 0.031
regulation of mapk cascade GO:0043408 262 0.030
protein processing GO:0016485 226 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.030
negative regulation of intracellular signal transduction GO:1902532 183 0.030
memory GO:0007613 3 0.030
membrane hyperpolarization GO:0060081 1 0.030
positive regulation of cell death GO:0010942 263 0.030
positive regulation of cell differentiation GO:0045597 211 0.029
ion transmembrane transport GO:0034220 338 0.029
rna transport GO:0050658 39 0.029
actin filament based process GO:0030029 224 0.029
purine nucleoside catabolic process GO:0006152 398 0.029
generation of neurons GO:0048699 152 0.029
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
cellular response to oxygen containing compound GO:1901701 276 0.028
positive regulation of protein kinase activity GO:0045860 190 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
cation transport GO:0006812 331 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.028
positive regulation of transferase activity GO:0051347 227 0.028
circadian behavior GO:0048512 2 0.027
secretion by cell GO:0032940 226 0.027
mitotic cell cycle process GO:1903047 286 0.027
peptidyl threonine phosphorylation GO:0018107 41 0.027
protein targeting GO:0006605 187 0.027
regulation of intracellular transport GO:0032386 195 0.026
intracellular protein transport GO:0006886 270 0.026
regulation of cellular response to stress GO:0080135 244 0.026
establishment of protein localization to organelle GO:0072594 172 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
lymphocyte activation GO:0046649 133 0.026
positive regulation of apoptotic signaling pathway GO:2001235 70 0.026
mapk cascade GO:0000165 288 0.026
mitotic cell cycle GO:0000278 326 0.026
developmental programmed cell death GO:0010623 3 0.026
neuron differentiation GO:0030182 138 0.026
lipid metabolic process GO:0006629 381 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
regulation of cell cycle GO:0051726 393 0.026
secretion GO:0046903 254 0.026
response to external biotic stimulus GO:0043207 261 0.026
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
maintenance of location GO:0051235 112 0.025
cell type specific apoptotic process GO:0097285 125 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
response to abiotic stimulus GO:0009628 336 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
response to biotic stimulus GO:0009607 276 0.025
compound eye development GO:0048749 1 0.025
response to radiation GO:0009314 151 0.025
negative regulation of cell death GO:0060548 345 0.025
ras protein signal transduction GO:0007265 73 0.025
protein homooligomerization GO:0051260 100 0.024
regulation of secretion by cell GO:1903530 177 0.024
cell part morphogenesis GO:0032990 137 0.024
stress activated protein kinase signaling cascade GO:0031098 94 0.024
protein maturation GO:0051604 233 0.024
nervous system development GO:0007399 293 0.024
t cell differentiation in thymus GO:0033077 4 0.024
regulation of reactive oxygen species metabolic process GO:2000377 41 0.024
lipid localization GO:0010876 106 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
positive regulation of developmental process GO:0051094 314 0.024
negative regulation of cell proliferation GO:0008285 228 0.024
negative regulation of apoptotic process GO:0043066 316 0.023
regulation of peptidase activity GO:0052547 180 0.023
spermatid development GO:0007286 4 0.023
regulation of cell activation GO:0050865 125 0.023
organic hydroxy compound metabolic process GO:1901615 147 0.023
metal ion transport GO:0030001 272 0.023
protein localization to organelle GO:0033365 280 0.023
cell cycle phase transition GO:0044770 173 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
establishment of rna localization GO:0051236 39 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
enzyme linked receptor protein signaling pathway GO:0007167 303 0.023
reactive oxygen species metabolic process GO:0072593 75 0.022
defense response to virus GO:0051607 71 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
positive regulation of proteolysis GO:0045862 142 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
membrane organization GO:0061024 292 0.022
cation transmembrane transport GO:0098655 238 0.022
endomembrane system organization GO:0010256 196 0.022
regulation of secretion GO:0051046 194 0.022
cellular lipid metabolic process GO:0044255 303 0.022
positive regulation of cytokine production GO:0001819 167 0.022
segmentation GO:0035282 4 0.022
mitotic cell cycle phase transition GO:0044772 162 0.022
locomotory behavior GO:0007626 1 0.022
melanin metabolic process GO:0006582 1 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
microtubule based process GO:0007017 210 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
response to other organism GO:0051707 261 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
rna export from nucleus GO:0006405 33 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
neuromuscular junction development GO:0007528 3 0.021
regulation of protein serine threonine kinase activity GO:0071900 179 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
actin cytoskeleton organization GO:0030036 207 0.020
cell cycle checkpoint GO:0000075 117 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
regeneration GO:0031099 4 0.020
regulation of cell differentiation GO:0045595 393 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
mrna transport GO:0051028 30 0.020
t cell activation GO:0042110 99 0.020
glycoprotein metabolic process GO:0009100 110 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
immune response regulating signaling pathway GO:0002764 97 0.020
dephosphorylation GO:0016311 209 0.020
cell projection morphogenesis GO:0048858 129 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
single organism membrane organization GO:0044802 268 0.020
activation of innate immune response GO:0002218 55 0.020
dna repair GO:0006281 198 0.020
vasculature development GO:0001944 181 0.020
regulation of response to wounding GO:1903034 101 0.020
positive regulation of protein transport GO:0051222 135 0.020
transport of virus GO:0046794 14 0.020
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of cell development GO:0060284 161 0.019
negative regulation of protein modification process GO:0031400 200 0.019
negative regulation of cell cycle process GO:0010948 121 0.019
negative regulation of protein processing GO:0010955 142 0.019
positive regulation of secretion GO:0051047 116 0.019
positive regulation of catabolic process GO:0009896 310 0.019
positive regulation of cell motility GO:2000147 177 0.019
regulation of homeostatic process GO:0032844 121 0.019
spermatid differentiation GO:0048515 4 0.019
neurogenesis GO:0022008 169 0.019
protein localization to nucleus GO:0034504 136 0.019
adaptive immune response GO:0002250 49 0.019
intracellular transport of virus GO:0075733 14 0.019
blastoderm segmentation GO:0007350 2 0.018
positive regulation of peptidase activity GO:0010952 88 0.018
sleep GO:0030431 2 0.018
protein import GO:0017038 130 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
regulation of dna metabolic process GO:0051052 153 0.018
nucleotide catabolic process GO:0009166 408 0.018
pattern recognition receptor signaling pathway GO:0002221 48 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
response to lipid GO:0033993 206 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
regulation of multi organism process GO:0043900 157 0.018
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
response to nitrogen compound GO:1901698 184 0.017
innate immune response activating signal transduction GO:0002758 48 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
multi organism intracellular transport GO:1902583 14 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
regulation of cell cycle phase transition GO:1901987 126 0.017
protein secretion GO:0009306 98 0.017
gtp metabolic process GO:0046039 239 0.017
regulation of jnk cascade GO:0046328 73 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
positive regulation of organelle organization GO:0010638 195 0.017
lipid biosynthetic process GO:0008610 177 0.017
regulation of transmembrane transport GO:0034762 139 0.016
positive regulation of cell activation GO:0050867 81 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
regulation of protein secretion GO:0050708 86 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
inflammatory response GO:0006954 79 0.016
jnk cascade GO:0007254 80 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
cardiovascular system development GO:0072358 262 0.016
organophosphate ester transport GO:0015748 32 0.016
chromatin organization GO:0006325 351 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
single organism cell adhesion GO:0098602 179 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
neuron development GO:0048666 113 0.016
rna localization GO:0006403 41 0.016
epithelium development GO:0060429 227 0.016
protein import into nucleus GO:0006606 104 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
endosomal transport GO:0016197 129 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 4 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
cellular chemical homeostasis GO:0055082 180 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
positive regulation of cell cycle process GO:0090068 106 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
negative regulation of cell cycle GO:0045786 193 0.016
oocyte differentiation GO:0009994 2 0.016
positive regulation of endopeptidase activity GO:0010950 84 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
double strand break repair GO:0006302 101 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
oocyte development GO:0048599 1 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
chemical homeostasis GO:0048878 306 0.015
ameboidal type cell migration GO:0001667 135 0.015
regulation of ion transport GO:0043269 189 0.015
nuclear division GO:0000280 128 0.015
positive regulation of defense response GO:0031349 87 0.015
regulation of immune effector process GO:0002697 91 0.015
interleukin 1 beta secretion GO:0050702 15 0.015
positive regulation of lymphocyte activation GO:0051251 73 0.015
regulation of cell adhesion GO:0030155 166 0.015
myeloid leukocyte differentiation GO:0002573 60 0.015
thymus development GO:0048538 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
cytokine secretion GO:0050663 64 0.015
mononuclear cell proliferation GO:0032943 71 0.015
cellular ion homeostasis GO:0006873 168 0.015
regulation of t cell activation GO:0050863 77 0.014
divalent inorganic cation transport GO:0072511 158 0.014
positive regulation of locomotion GO:0040017 186 0.014
defense response to bacterium GO:0042742 63 0.014
midgut development GO:0007494 1 0.014
protein autoprocessing GO:0016540 4 0.014
response to drug GO:0042493 81 0.014
small molecule biosynthetic process GO:0044283 157 0.014
plasma membrane organization GO:0007009 115 0.014
nucleoside phosphate biosynthetic process GO:1901293 109 0.014
positive regulation of cell migration GO:0030335 172 0.014
oxidation reduction process GO:0055114 396 0.014
tissue migration GO:0090130 119 0.014
myeloid cell differentiation GO:0030099 117 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.014
nuclear import GO:0051170 106 0.014
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
cation homeostasis GO:0055080 189 0.014
positive regulation of leukocyte activation GO:0002696 80 0.014
response to oxygen levels GO:0070482 100 0.014
response to wounding GO:0009611 168 0.014
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
myoblast fusion GO:0007520 1 0.014
organelle assembly GO:0070925 176 0.014
somatic muscle development GO:0007525 1 0.014
regulation of response to dna damage stimulus GO:2001020 94 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
circadian sleep wake cycle sleep GO:0050802 2 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
circulatory system development GO:0072359 262 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
ion homeostasis GO:0050801 230 0.013
cellular response to muramyl dipeptide GO:0071225 3 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
detection of muramyl dipeptide GO:0032498 1 0.013
adult locomotory behavior GO:0008344 1 0.013
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
response to bacterium GO:0009617 144 0.013
atp metabolic process GO:0046034 176 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
central nervous system development GO:0007417 123 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
regulation of membrane potential GO:0042391 95 0.013
positive regulation of protein secretion GO:0050714 60 0.013
cell division GO:0051301 168 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
immune system development GO:0002520 195 0.013
reproduction GO:0000003 63 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
neurological system process GO:0050877 163 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
chemotaxis GO:0006935 157 0.013
histone modification GO:0016570 251 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
negative regulation of proteolysis GO:0045861 132 0.013
regulation of cell projection organization GO:0031344 107 0.013
detection of stimulus GO:0051606 85 0.013
leukocyte proliferation GO:0070661 74 0.013
positive regulation of humoral immune response GO:0002922 3 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
response to organic cyclic compound GO:0014070 204 0.013
regulation of antimicrobial humoral response GO:0002759 1 0.013
regulation of protein targeting GO:1903533 91 0.013
regulation of protein catabolic process GO:0042176 155 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
single organismal cell cell adhesion GO:0016337 148 0.012
cellular response to lipid GO:0071396 127 0.012
hemopoiesis GO:0030097 180 0.012
regulation of chromosome organization GO:0033044 103 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
cell chemotaxis GO:0060326 112 0.012
t cell homeostasis GO:0043029 3 0.012
response to light stimulus GO:0009416 87 0.012
anterior posterior axis specification GO:0009948 2 0.012
positive regulation of cell cycle GO:0045787 140 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
peripheral nervous system development GO:0007422 2 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
covalent chromatin modification GO:0016569 254 0.012
response to virus GO:0009615 126 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
macromolecule glycosylation GO:0043413 63 0.012
protein ubiquitination GO:0016567 314 0.012
cell fate determination GO:0001709 3 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
purine containing compound biosynthetic process GO:0072522 88 0.012
single organism reproductive process GO:0044702 98 0.012
embryo development GO:0009790 123 0.012
regulation of transporter activity GO:0032409 82 0.012
mitochondrion organization GO:0007005 156 0.012
toxin transport GO:1901998 4 0.012
negative regulation of transport GO:0051051 176 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
response to uv GO:0009411 73 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
actin filament organization GO:0007015 128 0.012
phospholipid transport GO:0015914 23 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
autophagic cell death GO:0048102 3 0.012
sulfur compound metabolic process GO:0006790 101 0.012
circadian sleep wake cycle process GO:0022410 2 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
regulation of cytokine secretion GO:0050707 57 0.012
rho protein signal transduction GO:0007266 26 0.012
positive regulation of dna metabolic process GO:0051054 73 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
regulation of interleukin 1 beta secretion GO:0050706 12 0.011
calcium ion transport GO:0006816 147 0.011
positive regulation of multi organism process GO:0043902 56 0.011
negative regulation of protein maturation GO:1903318 142 0.011
negative regulation of protein kinase activity GO:0006469 98 0.011
regulation of protein processing GO:0070613 150 0.011
response to axon injury GO:0048678 1 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
alcohol metabolic process GO:0006066 114 0.011
chromatin modification GO:0016568 298 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
taxis GO:0042330 157 0.011
regulation of cell division GO:0051302 116 0.011
neuroblast proliferation GO:0007405 4 0.011
epithelial cell migration GO:0010631 119 0.011
positive regulation of cytokine secretion GO:0050715 42 0.011
anatomical structure homeostasis GO:0060249 100 0.011
leukocyte cell cell adhesion GO:0007159 37 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
response to fungus GO:0009620 4 0.011
regulation of leukocyte proliferation GO:0070663 67 0.011
lymphocyte migration GO:0072676 28 0.011
negative regulation of organelle organization GO:0010639 126 0.011
glycosylation GO:0070085 71 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
peptide metabolic process GO:0006518 51 0.011

MLKL disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.018
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
eye and adnexa disease DOID:1492 150 0.016
disease of cellular proliferation DOID:14566 174 0.015
musculoskeletal system disease DOID:17 223 0.015
eye disease DOID:5614 149 0.015
immune system disease DOID:2914 155 0.014
cancer DOID:162 167 0.012
central nervous system disease DOID:331 186 0.011
organ system cancer DOID:0050686 164 0.011