Homo sapiens

0 known processes

PSMC1

proteasome (prosome, macropain) 26S subunit, ATPase, 1

(Aliases: P26S4,MGC24583,p56,MGC8541,S4)

PSMC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.999
proteasomal protein catabolic process GO:0010498 176 0.989
modification dependent protein catabolic process GO:0019941 209 0.988
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.985
proteasome regulatory particle assembly GO:0070682 2 0.983
proteasome assembly GO:0043248 7 0.983
ubiquitin dependent protein catabolic process GO:0006511 206 0.981
blastocyst development GO:0001824 3 0.981
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.980
modification dependent macromolecule catabolic process GO:0043632 212 0.975
cellular protein catabolic process GO:0044257 261 0.973
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.972
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.971
determination of adult lifespan GO:0008340 2 0.961
Worm
post embryonic development GO:0009791 2 0.955
mitotic spindle elongation GO:0000022 4 0.954
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.953
cellular macromolecule catabolic process GO:0044265 380 0.932
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.924
protein catabolic process GO:0030163 325 0.902
Worm
dna templated transcription initiation GO:0006352 35 0.891
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.889
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.883
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.870
multicellular organismal aging GO:0010259 3 0.863
Worm
regulation of proteasomal protein catabolic process GO:0061136 87 0.834
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.792
nucleotide excision repair GO:0006289 31 0.745
cellular response to dna damage stimulus GO:0006974 379 0.725
Fly
regulation of protein complex assembly GO:0043254 147 0.673
regulation of peptidase activity GO:0052547 180 0.667
purine nucleoside monophosphate catabolic process GO:0009128 158 0.593
cellular macromolecular complex assembly GO:0034622 324 0.572
positive regulation of peptidase activity GO:0010952 88 0.559
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.538
aging GO:0007568 66 0.535
Worm
spindle elongation GO:0051231 4 0.514
Fly
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.474
regulation of cellular component biogenesis GO:0044087 281 0.473
regulation of dna templated transcription initiation GO:2000142 9 0.451
positive regulation of protein complex assembly GO:0031334 86 0.426
ribonucleoside catabolic process GO:0042454 406 0.412
regulation of mitosis GO:0007088 63 0.408
purine nucleoside catabolic process GO:0006152 398 0.379
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.377
atp catabolic process GO:0006200 157 0.356
positive regulation of cellular component organization GO:0051130 376 0.330
negative regulation of peptidase activity GO:0010466 91 0.327
dna repair GO:0006281 198 0.309
purine ribonucleotide catabolic process GO:0009154 404 0.301
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.301
positive regulation of endopeptidase activity GO:0010950 84 0.291
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.285
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.271
cellular protein complex assembly GO:0043623 188 0.265
chromosome separation GO:0051304 23 0.265
nucleoside catabolic process GO:0009164 408 0.262
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.255
positive regulation of cellular component biogenesis GO:0044089 158 0.255
purine ribonucleoside catabolic process GO:0046130 398 0.250
regulation of endopeptidase activity GO:0052548 170 0.249
protein dna complex subunit organization GO:0071824 80 0.241
spermatid differentiation GO:0048515 4 0.239
ribonucleoside triphosphate metabolic process GO:0009199 412 0.222
ribonucleoside monophosphate catabolic process GO:0009158 158 0.205
purine nucleotide catabolic process GO:0006195 405 0.205
protein dna complex assembly GO:0065004 64 0.201
nucleoside monophosphate catabolic process GO:0009125 159 0.199
ribonucleoside triphosphate catabolic process GO:0009203 391 0.198
protein deubiquitination GO:0016579 79 0.197
oogenesis GO:0048477 2 0.193
positive regulation of proteolysis GO:0045862 142 0.189
purine containing compound catabolic process GO:0072523 411 0.188
spermatid development GO:0007286 4 0.185
double strand break repair GO:0006302 101 0.185
ribonucleotide catabolic process GO:0009261 405 0.183
metaphase anaphase transition of cell cycle GO:0044784 21 0.179
molting cycle GO:0042303 28 0.176
regulation of mitotic cell cycle GO:0007346 189 0.168
nucleoside phosphate catabolic process GO:1901292 412 0.167
cell division GO:0051301 168 0.160
purine nucleoside triphosphate catabolic process GO:0009146 392 0.155
negative regulation of endopeptidase activity GO:0010951 84 0.151
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.150
atp metabolic process GO:0046034 176 0.150
regulation of proteolysis GO:0030162 293 0.149
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.142
negative regulation of apoptotic process GO:0043066 316 0.135
nucleotide catabolic process GO:0009166 408 0.128
purine nucleoside triphosphate metabolic process GO:0009144 412 0.125
regulation of apoptotic signaling pathway GO:2001233 175 0.124
apoptotic mitochondrial changes GO:0008637 57 0.121
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.120
positive regulation of dna templated transcription elongation GO:0032786 18 0.120
nucleoside triphosphate catabolic process GO:0009143 394 0.116
glycosyl compound catabolic process GO:1901658 413 0.111
regulation of protein ubiquitination GO:0031396 95 0.111
mitotic sister chromatid segregation GO:0000070 53 0.108
mitotic cell cycle process GO:1903047 286 0.107
Fly
positive regulation of catabolic process GO:0009896 310 0.106
chromatin organization GO:0006325 351 0.105
positive regulation of phosphorylation GO:0042327 394 0.105
ribonucleoside monophosphate metabolic process GO:0009161 187 0.102
regulation of kinase activity GO:0043549 314 0.102
regulation of protein catabolic process GO:0042176 155 0.101
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.099
epithelial cell differentiation GO:0030855 141 0.099
negative regulation of cell death GO:0060548 345 0.093
lens development in camera type eye GO:0002088 2 0.093
regulation of dna templated transcription elongation GO:0032784 23 0.090
regulation of cellular protein catabolic process GO:1903362 96 0.086
positive regulation of protein catabolic process GO:0045732 75 0.085
negative regulation of proteolysis GO:0045861 132 0.083
microtubule based process GO:0007017 210 0.082
Fly
chemical homeostasis GO:0048878 306 0.082
protein localization to nucleus GO:0034504 136 0.081
nucleoside triphosphate metabolic process GO:0009141 422 0.081
recombinational repair GO:0000725 50 0.080
embryo development GO:0009790 123 0.079
Worm
mitotic spindle organization GO:0007052 27 0.076
Fly
chordate embryonic development GO:0043009 34 0.076
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.076
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.075
spindle organization GO:0007051 53 0.074
Fly
apoptotic signaling pathway GO:0097190 268 0.073
organophosphate catabolic process GO:0046434 430 0.073
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.073
dna templated transcription elongation GO:0006354 25 0.071
negative regulation of programmed cell death GO:0043069 321 0.070
regulation of mapk cascade GO:0043408 262 0.068
chromatin modification GO:0016568 298 0.068
purine ribonucleoside metabolic process GO:0046128 437 0.068
regulation of cell division GO:0051302 116 0.066
chromosome segregation GO:0007059 114 0.064
positive regulation of cellular catabolic process GO:0031331 284 0.060
purine nucleoside monophosphate metabolic process GO:0009126 186 0.057
regulation of cell cycle GO:0051726 393 0.057
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.054
regulation of establishment of protein localization GO:0070201 242 0.052
ovarian follicle development GO:0001541 5 0.052
growth GO:0040007 202 0.051
positive regulation of dna templated transcription initiation GO:2000144 5 0.050
negative regulation of apoptotic signaling pathway GO:2001234 97 0.050
protein deglycosylation GO:0006517 2 0.049
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.049
regulation of peptide transport GO:0090087 62 0.047
positive regulation of protein phosphorylation GO:0001934 313 0.046
er associated misfolded protein catabolic process GO:0071712 1 0.045
microtubule organizing center organization GO:0031023 62 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.042
double strand break repair via homologous recombination GO:0000724 50 0.042
reproduction GO:0000003 63 0.042
Worm
regulation of cell cycle process GO:0010564 266 0.041
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.041
protein modification by small protein conjugation GO:0032446 342 0.041
single organism cellular localization GO:1902580 332 0.041
signal transduction by phosphorylation GO:0023014 297 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
regulation of response to external stimulus GO:0032101 222 0.040
microtubule cytoskeleton organization GO:0000226 176 0.037
Fly
nuclear division GO:0000280 128 0.037
Fly
nervous system development GO:0007399 293 0.037
negative regulation of phosphorylation GO:0042326 174 0.036
meiosis i GO:0007127 4 0.036
regulation of cell growth GO:0001558 135 0.034
regulation of mitochondrion organization GO:0010821 54 0.034
regulation of immune response GO:0050776 201 0.034
neurogenesis GO:0022008 169 0.033
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.033
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.033
regulation of sister chromatid segregation GO:0033045 27 0.032
regulation of protein import into nucleus GO:0042306 78 0.032
regulation of protein serine threonine kinase activity GO:0071900 179 0.031
nucleoside monophosphate metabolic process GO:0009123 191 0.031
embryo development ending in birth or egg hatching GO:0009792 34 0.030
Worm
positive regulation of kinase activity GO:0033674 204 0.030
mapk cascade GO:0000165 288 0.030
multicellular organism reproduction GO:0032504 42 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
protein import GO:0017038 130 0.029
regulation of growth GO:0040008 165 0.029
regulation of mitotic sister chromatid separation GO:0010965 27 0.028
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.028
regulation of protein kinase activity GO:0045859 289 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.026
negative regulation of protein maturation GO:1903318 142 0.026
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.026
negative regulation of protein processing GO:0010955 142 0.026
regulation of cellular response to stress GO:0080135 244 0.026
mitotic nuclear division GO:0007067 119 0.025
Fly
regulation of exit from mitosis GO:0007096 6 0.025
mitochondrion organization GO:0007005 156 0.024
rna catabolic process GO:0006401 71 0.024
sensory organ development GO:0007423 52 0.024
regulation of chromosome organization GO:0033044 103 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.024
regulation of nf kappab import into nucleus GO:0042345 22 0.023
positive regulation of protein ubiquitination GO:0031398 53 0.023
tissue regeneration GO:0042246 3 0.023
epithelium development GO:0060429 227 0.022
regulation of protein localization GO:0032880 296 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.022
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.022
regulation of protein maturation GO:1903317 150 0.022
rna interference GO:0016246 4 0.022
negative regulation of protein transport GO:0051224 75 0.021
i kappab kinase nf kappab signaling GO:0007249 166 0.021
regulation of nuclear division GO:0051783 65 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
monoubiquitinated histone deubiquitination GO:0035521 3 0.021
positive regulation of cellular protein catabolic process GO:1903364 37 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
maintenance of location GO:0051235 112 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
cell cell signaling GO:0007267 155 0.020
regulation of mitotic sister chromatid segregation GO:0033047 27 0.020
positive regulation of cell cycle GO:0045787 140 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.020
regulation of protein transport GO:0051223 213 0.020
nuclear import GO:0051170 106 0.020
maintenance of protein location in cell GO:0032507 56 0.019
female gamete generation GO:0007292 2 0.019
release of cytochrome c from mitochondria GO:0001836 35 0.019
regulation of intracellular transport GO:0032386 195 0.019
cardiovascular system development GO:0072358 262 0.019
negative regulation of response to dna damage stimulus GO:2001021 33 0.019
cell growth GO:0016049 160 0.019
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
sister chromatid segregation GO:0000819 54 0.018
spindle assembly GO:0051225 29 0.018
Fly
protein k63 linked deubiquitination GO:0070536 21 0.017
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.017
heart development GO:0007507 95 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.017
mitotic sister chromatid separation GO:0051306 18 0.017
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.017
binding of sperm to zona pellucida GO:0007339 3 0.017
extrinsic apoptotic signaling pathway GO:0097191 119 0.016
response to wounding GO:0009611 168 0.016
regulation of protein processing GO:0070613 150 0.016
secretion by cell GO:0032940 226 0.016
Worm
stress activated mapk cascade GO:0051403 93 0.016
regulation of protein localization to nucleus GO:1900180 85 0.016
ossification GO:0001503 121 0.016
mitotic cell cycle phase transition GO:0044772 162 0.015
cell cycle phase transition GO:0044770 173 0.015
protein secretion GO:0009306 98 0.015
Worm
negative regulation of cytoplasmic transport GO:1903650 46 0.015
regulation of transferase activity GO:0051338 355 0.015
positive regulation of apoptotic process GO:0043065 246 0.014
ovulation cycle process GO:0022602 9 0.014
double strand break repair via nonhomologous end joining GO:0006303 10 0.014
protein ubiquitination GO:0016567 314 0.014
antigen processing and presentation of exogenous antigen GO:0019884 4 0.014
regulation of protein targeting GO:1903533 91 0.014
mitotic cell cycle GO:0000278 326 0.013
Fly
signal transduction by p53 class mediator GO:0072331 72 0.013
single organism nuclear import GO:1902593 104 0.013
non recombinational repair GO:0000726 14 0.013
regulation of chromosome segregation GO:0051983 44 0.013
protein processing GO:0016485 226 0.013
protein maturation GO:0051604 233 0.013
protein modification by small protein removal GO:0070646 92 0.012
spermatogenesis GO:0007283 22 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
sperm egg recognition GO:0035036 3 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
negative regulation of intracellular protein transport GO:0090317 42 0.012
protein autophosphorylation GO:0046777 123 0.012
oocyte development GO:0048599 1 0.012
lipid transport GO:0006869 90 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.012
Fly
regulation of response to dna damage stimulus GO:2001020 94 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.011
protein import into nucleus GO:0006606 104 0.011
nf kappab import into nucleus GO:0042348 22 0.011
regulation of signal transduction by p53 class mediator GO:1901796 26 0.011
trna splicing via endonucleolytic cleavage and ligation GO:0006388 7 0.011
osteoblast differentiation GO:0001649 92 0.011
negative regulation of intracellular transport GO:0032387 60 0.011
ncrna metabolic process GO:0034660 108 0.011
nitrogen compound transport GO:0071705 191 0.011
regulation of defense response GO:0031347 154 0.011
lens fiber cell differentiation GO:0070306 2 0.011
negative regulation of protein import into nucleus GO:0042308 30 0.011
negative regulation of response to wounding GO:1903035 47 0.010
camera type eye development GO:0043010 25 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
leukocyte differentiation GO:0002521 98 0.010
protein targeting to nucleus GO:0044744 104 0.010

PSMC1 disease predictions

Disease DO term ID Size Probability Func Analog Org