Homo sapiens

96 known processes

PSMC2

proteasome (prosome, macropain) 26S subunit, ATPase, 2

(Aliases: MSS1,S7,Nbla10058,MGC3004)

PSMC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome regulatory particle assembly GO:0070682 2 1.000
Yeast
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.999
Yeast
cellular protein catabolic process GO:0044257 261 0.995
proteasomal protein catabolic process GO:0010498 176 0.984
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.980
ubiquitin dependent protein catabolic process GO:0006511 206 0.980
nucleotide excision repair GO:0006289 31 0.979
modification dependent macromolecule catabolic process GO:0043632 212 0.955
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.955
regulation of proteasomal protein catabolic process GO:0061136 87 0.951
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.948
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.947
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.941
determination of adult lifespan GO:0008340 2 0.928
Worm
cellular macromolecule catabolic process GO:0044265 380 0.924
cellular response to dna damage stimulus GO:0006974 379 0.918
Fly
multicellular organismal aging GO:0010259 3 0.913
Worm
blastocyst development GO:0001824 3 0.902
modification dependent protein catabolic process GO:0019941 209 0.896
protein catabolic process GO:0030163 325 0.893
proteasome assembly GO:0043248 7 0.888
Yeast
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.873
dna templated transcription initiation GO:0006352 35 0.870
Yeast
post embryonic development GO:0009791 2 0.749
Worm
dna repair GO:0006281 198 0.731
protein deubiquitination GO:0016579 79 0.707
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.692
Yeast
mitotic spindle elongation GO:0000022 4 0.657
cellular macromolecular complex assembly GO:0034622 324 0.538
Yeast
positive regulation of peptidase activity GO:0010952 88 0.535
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.530
purine nucleoside monophosphate catabolic process GO:0009128 158 0.513
regulation of peptidase activity GO:0052547 180 0.452
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.407
Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.378
Yeast
cellular protein complex assembly GO:0043623 188 0.373
Yeast
protein modification by small protein removal GO:0070646 92 0.350
regulation of protein complex assembly GO:0043254 147 0.325
Yeast
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.323
regulation of proteolysis GO:0030162 293 0.321
spindle elongation GO:0051231 4 0.318
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.288
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.232
Yeast
negative regulation of peptidase activity GO:0010466 91 0.229
positive regulation of endopeptidase activity GO:0010950 84 0.224
embryo development GO:0009790 123 0.220
Worm
positive regulation of protein complex assembly GO:0031334 86 0.219
Yeast
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.210
purine ribonucleotide catabolic process GO:0009154 404 0.209
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.205
protein k63 linked deubiquitination GO:0070536 21 0.204
apoptotic mitochondrial changes GO:0008637 57 0.204
regulation of endopeptidase activity GO:0052548 170 0.199
aging GO:0007568 66 0.186
Worm
regulation of cellular protein catabolic process GO:1903362 96 0.178
purine nucleoside catabolic process GO:0006152 398 0.175
embryo development ending in birth or egg hatching GO:0009792 34 0.169
Worm
apoptotic signaling pathway GO:0097190 268 0.158
microtubule cytoskeleton organization GO:0000226 176 0.150
protein deglycosylation GO:0006517 2 0.146
chromosome separation GO:0051304 23 0.145
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.145
positive regulation of proteolysis GO:0045862 142 0.139
negative regulation of endopeptidase activity GO:0010951 84 0.128
negative regulation of proteolysis GO:0045861 132 0.123
regulation of protein ubiquitination GO:0031396 95 0.120
ribonucleoside catabolic process GO:0042454 406 0.119
nuclear division GO:0000280 128 0.118
negative regulation of protein maturation GO:1903318 142 0.116
mitochondrion organization GO:0007005 156 0.116
positive regulation of cellular component biogenesis GO:0044089 158 0.113
Yeast
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.104
microtubule based process GO:0007017 210 0.103
spermatid development GO:0007286 4 0.091
metaphase anaphase transition of cell cycle GO:0044784 21 0.087
regulation of cell division GO:0051302 116 0.087
mitotic cell cycle process GO:1903047 286 0.087
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.084
Yeast
regulation of cellular component biogenesis GO:0044087 281 0.083
Yeast
glycosyl compound catabolic process GO:1901658 413 0.081
spermatid differentiation GO:0048515 4 0.080
nucleoside catabolic process GO:0009164 408 0.077
monoubiquitinated protein deubiquitination GO:0035520 6 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.075
organelle fission GO:0048285 149 0.074
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.074
monoubiquitinated histone deubiquitination GO:0035521 3 0.072
chordate embryonic development GO:0043009 34 0.071
spindle assembly GO:0051225 29 0.067
multicellular organism reproduction GO:0032504 42 0.066
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.066
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.065
purine nucleotide catabolic process GO:0006195 405 0.065
regulation of cell cycle GO:0051726 393 0.062
molting cycle GO:0042303 28 0.060
oogenesis GO:0048477 2 0.057
regulation of cell growth GO:0001558 135 0.056
regulation of kinase activity GO:0043549 314 0.051
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.049
regulation of mitotic cell cycle GO:0007346 189 0.048
positive regulation of protein catabolic process GO:0045732 75 0.048
Yeast
protein dna complex subunit organization GO:0071824 80 0.047
Yeast
regulation of apoptotic signaling pathway GO:2001233 175 0.046
recombinational repair GO:0000725 50 0.045
organelle assembly GO:0070925 176 0.043
female gamete generation GO:0007292 2 0.042
secretion GO:0046903 254 0.041
nervous system development GO:0007399 293 0.041
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.041
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.040
regulation of protein catabolic process GO:0042176 155 0.040
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 158 0.040
rna interference GO:0016246 4 0.038
nucleoside monophosphate catabolic process GO:0009125 159 0.037
negative regulation of apoptotic process GO:0043066 316 0.037
regulation of protein maturation GO:1903317 150 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.035
chromosome segregation GO:0007059 114 0.034
double strand break repair GO:0006302 101 0.033
positive regulation of protein ubiquitination GO:0031398 53 0.033
purine nucleoside monophosphate metabolic process GO:0009126 186 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
microtubule organizing center organization GO:0031023 62 0.033
protein processing GO:0016485 226 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.032
regulation of mitosis GO:0007088 63 0.032
protein secretion GO:0009306 98 0.031
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.031
positive regulation of cellular protein catabolic process GO:1903364 37 0.031
secretion by cell GO:0032940 226 0.031
release of cytochrome c from mitochondria GO:0001836 35 0.031
signal transduction in response to dna damage GO:0042770 57 0.031
atp metabolic process GO:0046034 176 0.030
protein dna complex assembly GO:0065004 64 0.029
Yeast
protein modification by small protein conjugation GO:0032446 342 0.028
ribonucleotide catabolic process GO:0009261 405 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
epithelium development GO:0060429 227 0.027
lens development in camera type eye GO:0002088 2 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
mitotic cell cycle GO:0000278 326 0.026
regulation of protein processing GO:0070613 150 0.026
reproduction GO:0000003 63 0.025
Worm
cell division GO:0051301 168 0.024
signal transduction by p53 class mediator GO:0072331 72 0.024
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.023
mitotic sister chromatid segregation GO:0000070 53 0.023
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.022
positive regulation of dna templated transcription elongation GO:0032786 18 0.022
mitotic spindle organization GO:0007052 27 0.022
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.022
meiotic chromosome segregation GO:0045132 4 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
protein maturation GO:0051604 233 0.021
negative regulation of protein processing GO:0010955 142 0.020
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.020
cell growth GO:0016049 160 0.019
positive regulation of kinase activity GO:0033674 204 0.019
protein ubiquitination GO:0016567 314 0.019
positive regulation of cell cycle GO:0045787 140 0.018
dna templated transcription elongation GO:0006354 25 0.018
negative regulation of phosphorylation GO:0042326 174 0.017
histone deubiquitination GO:0016578 16 0.017
regulation of cellular response to stress GO:0080135 244 0.017
nucleotide catabolic process GO:0009166 408 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
regulation of transferase activity GO:0051338 355 0.016
double strand break repair via homologous recombination GO:0000724 50 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of cell cycle process GO:0010564 266 0.014
negative regulation of cell death GO:0060548 345 0.014
organophosphate catabolic process GO:0046434 430 0.014
defense response GO:0006952 315 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
regulation of dna templated transcription initiation GO:2000142 9 0.014
Yeast
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
protein deneddylation GO:0000338 10 0.014
mitotic nuclear division GO:0007067 119 0.013
atp catabolic process GO:0006200 157 0.013
negative regulation of mitochondrion organization GO:0010823 22 0.013
regulation of signal transduction by p53 class mediator GO:1901796 26 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
response to virus GO:0009615 126 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
non recombinational repair GO:0000726 14 0.012
protein k48 linked deubiquitination GO:0071108 19 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.011
regulation of mitochondrion organization GO:0010821 54 0.011
spermatogenesis GO:0007283 22 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.011
regulation of growth GO:0040008 165 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
brain morphogenesis GO:0048854 1 0.011
double strand break repair via nonhomologous end joining GO:0006303 10 0.011
response to external biotic stimulus GO:0043207 261 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
Yeast
sensory organ development GO:0007423 52 0.010
vesicle mediated transport GO:0016192 371 0.010
single organism reproductive process GO:0044702 98 0.010
negative regulation of cellular protein catabolic process GO:1903363 38 0.010
multicellular organismal response to stress GO:0033555 1 0.010
ribonucleoside triphosphate catabolic process GO:0009203 391 0.010
anatomical structure homeostasis GO:0060249 100 0.010

PSMC2 disease predictions

Disease DO term ID Size Probability Func Analog Org