Homo sapiens

0 known processes

PSMC3

proteasome (prosome, macropain) 26S subunit, ATPase, 3

(Aliases: TBP1,MGC8487)

PSMC3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 212 0.973
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.955
Yeast
modification dependent protein catabolic process GO:0019941 209 0.949
Yeast
proteasome assembly GO:0043248 7 0.948
Yeast
cellular macromolecule catabolic process GO:0044265 380 0.945
Yeast
cellular protein catabolic process GO:0044257 261 0.944
Yeast
proteasome regulatory particle assembly GO:0070682 2 0.938
Yeast
ubiquitin dependent protein catabolic process GO:0006511 206 0.936
Yeast
multicellular organismal aging GO:0010259 3 0.930
Worm
determination of adult lifespan GO:0008340 2 0.928
Worm
cellular macromolecular complex assembly GO:0034622 324 0.911
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.844
post embryonic development GO:0009791 2 0.811
Worm
proteasomal protein catabolic process GO:0010498 176 0.797
protein catabolic process GO:0030163 325 0.779
Yeast
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.778
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.744
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.707
Yeast
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.705
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.661
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.626
Yeast
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.622
Yeast
protein dna complex subunit organization GO:0071824 80 0.593
Yeast
dna templated transcription initiation GO:0006352 35 0.593
Yeast
blastocyst development GO:0001824 3 0.582
Mouse
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.534
cellular protein complex assembly GO:0043623 188 0.505
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.444
spindle elongation GO:0051231 4 0.416
dna templated transcriptional preinitiation complex assembly GO:0070897 5 0.394
Yeast
ribonucleoside catabolic process GO:0042454 406 0.393
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.368
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 412 0.363
embryo development GO:0009790 123 0.350
Mouse Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.345
atp metabolic process GO:0046034 176 0.325
positive regulation of peptidase activity GO:0010952 88 0.307
purine nucleoside triphosphate metabolic process GO:0009144 412 0.279
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.277
purine nucleoside catabolic process GO:0006152 398 0.270
regulation of dna templated transcription initiation GO:2000142 9 0.269
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.248
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.238
nucleoside monophosphate metabolic process GO:0009123 191 0.238
purine ribonucleotide catabolic process GO:0009154 404 0.234
positive regulation of cellular component organization GO:0051130 376 0.231
Yeast
protein dna complex assembly GO:0065004 64 0.219
Yeast
oogenesis GO:0048477 2 0.212
dna repair GO:0006281 198 0.209
mitotic cell cycle process GO:1903047 286 0.200
purine nucleoside monophosphate metabolic process GO:0009126 186 0.197
embryo development ending in birth or egg hatching GO:0009792 34 0.171
Mouse Worm
regulation of cellular component biogenesis GO:0044087 281 0.166
Yeast
mitotic spindle elongation GO:0000022 4 0.156
purine containing compound catabolic process GO:0072523 411 0.154
nucleotide catabolic process GO:0009166 408 0.142
establishment of nucleus localization GO:0040023 1 0.142
regulation of mitotic cell cycle GO:0007346 189 0.142
regulation of peptidase activity GO:0052547 180 0.133
aging GO:0007568 66 0.133
Worm
ribonucleoside monophosphate metabolic process GO:0009161 187 0.124
cell division GO:0051301 168 0.120
purine nucleotide catabolic process GO:0006195 405 0.109
chromatin organization GO:0006325 351 0.106
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.105
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.104
nucleoside phosphate catabolic process GO:1901292 412 0.098
single organism membrane organization GO:0044802 268 0.096
positive regulation of cellular component biogenesis GO:0044089 158 0.092
Yeast
nuclear division GO:0000280 128 0.092
nucleotide excision repair GO:0006289 31 0.092
reproduction GO:0000003 63 0.091
Worm
chemical homeostasis GO:0048878 306 0.091
chromatin modification GO:0016568 298 0.091
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.089
positive regulation of protein complex assembly GO:0031334 86 0.086
Yeast
positive regulation of endopeptidase activity GO:0010950 84 0.086
purine nucleoside monophosphate catabolic process GO:0009128 158 0.085
nucleoside triphosphate catabolic process GO:0009143 394 0.079
rna interference GO:0016246 4 0.076
microtubule cytoskeleton organization GO:0000226 176 0.076
mitotic cell cycle GO:0000278 326 0.072
regulation of protein complex assembly GO:0043254 147 0.066
Yeast
protein secretion GO:0009306 98 0.065
positive regulation of cellular catabolic process GO:0031331 284 0.064
dna templated transcription elongation GO:0006354 25 0.062
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.062
organelle fission GO:0048285 149 0.059
ribonucleotide catabolic process GO:0009261 405 0.057
ribonucleoside monophosphate catabolic process GO:0009158 158 0.057
ribonucleotide biosynthetic process GO:0009260 81 0.057
mitochondrion organization GO:0007005 156 0.056
purine ribonucleoside catabolic process GO:0046130 398 0.055
nucleus localization GO:0051647 1 0.055
regulation of cell growth GO:0001558 135 0.053
nucleoside catabolic process GO:0009164 408 0.052
mitotic nuclear division GO:0007067 119 0.052
ribonucleoside triphosphate catabolic process GO:0009203 391 0.048
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.046
glycosyl compound catabolic process GO:1901658 413 0.046
metaphase anaphase transition of cell cycle GO:0044784 21 0.045
cytoplasmic transport GO:0016482 379 0.044
regulation of protein ubiquitination GO:0031396 95 0.043
microtubule based process GO:0007017 210 0.043
nucleoside monophosphate catabolic process GO:0009125 159 0.042
regulation of gene expression epigenetic GO:0040029 73 0.042
organophosphate catabolic process GO:0046434 430 0.041
regulation of proteasomal protein catabolic process GO:0061136 87 0.041
multicellular organism reproduction GO:0032504 42 0.040
regulation of mitosis GO:0007088 63 0.040
growth GO:0040007 202 0.037
regulation of dna templated transcription elongation GO:0032784 23 0.036
regulation of membrane potential GO:0042391 95 0.036
positive regulation of hydrolase activity GO:0051345 331 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.032
rna splicing via transesterification reactions GO:0000375 90 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.031
positive regulation of catabolic process GO:0009896 310 0.031
regulation of cell cycle process GO:0010564 266 0.030
molting cycle GO:0042303 28 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
regulation of mapk cascade GO:0043408 262 0.030
regulation of proteolysis GO:0030162 293 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
regulation of cell division GO:0051302 116 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
spermatid differentiation GO:0048515 4 0.027
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 10 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.026
negative regulation of peptidase activity GO:0010466 91 0.026
apoptotic signaling pathway GO:0097190 268 0.026
secretion by cell GO:0032940 226 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
nervous system development GO:0007399 293 0.024
negative regulation of endopeptidase activity GO:0010951 84 0.024
positive regulation of proteolysis GO:0045862 142 0.023
mitotic cell cycle phase transition GO:0044772 162 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.023
cell cell signaling GO:0007267 155 0.023
development of primary sexual characteristics GO:0045137 35 0.023
protein maturation GO:0051604 233 0.023
reproductive process GO:0022414 106 0.022
regulation of behavior GO:0050795 82 0.022
response to wounding GO:0009611 168 0.021
purine ribonucleotide biosynthetic process GO:0009152 79 0.021
positive regulation of protein catabolic process GO:0045732 75 0.021
receptor mediated endocytosis GO:0006898 84 0.020
membrane organization GO:0061024 292 0.020
cellular lipid metabolic process GO:0044255 303 0.020
secretion GO:0046903 254 0.020
regulation of immune response GO:0050776 201 0.019
female gamete generation GO:0007292 2 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
taxis GO:0042330 157 0.019
regulation of mitochondrion organization GO:0010821 54 0.018
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.018
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.018
neurogenesis GO:0022008 169 0.018
spindle organization GO:0007051 53 0.018
reproductive system development GO:0061458 56 0.018
chromosome segregation GO:0007059 114 0.017
endocytosis GO:0006897 159 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
atp catabolic process GO:0006200 157 0.017
protein import GO:0017038 130 0.017
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 13 0.017
response to virus GO:0009615 126 0.016
regulation of growth GO:0040008 165 0.016
chromatin remodeling GO:0006338 55 0.016
regulation of nuclear division GO:0051783 65 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
immune response GO:0006955 307 0.016
nuclear migration GO:0007097 1 0.016
positive regulation of dna templated transcription initiation GO:2000144 5 0.016
Yeast
cell growth GO:0016049 160 0.016
lipid metabolic process GO:0006629 381 0.015
protein deglycosylation GO:0006517 2 0.015
positive regulation of protein ubiquitination GO:0031398 53 0.015
chromosome separation GO:0051304 23 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.015
cell cycle phase transition GO:0044770 173 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.014
rna catabolic process GO:0006401 71 0.014
calcium ion transport GO:0006816 147 0.014
defense response GO:0006952 315 0.014
er to golgi vesicle mediated transport GO:0006888 19 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.013
organelle assembly GO:0070925 176 0.013
negative regulation of protein transport GO:0051224 75 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
cellular ketone metabolic process GO:0042180 80 0.013
double strand break repair GO:0006302 101 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
single organism membrane fusion GO:0044801 37 0.012
protein processing GO:0016485 226 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
protein localization to organelle GO:0033365 280 0.012
transmembrane transport GO:0055085 399 0.012
sex differentiation GO:0007548 45 0.012
ribonucleoside biosynthetic process GO:0042455 25 0.012
adult locomotory behavior GO:0008344 1 0.012
regulation of chromosome segregation GO:0051983 44 0.012
negative regulation of proteolysis GO:0045861 132 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.011
ovarian follicle development GO:0001541 5 0.011
ribose phosphate biosynthetic process GO:0046390 82 0.011
vesicle mediated transport GO:0016192 371 0.011
single organism cellular localization GO:1902580 332 0.011
single organism reproductive process GO:0044702 98 0.011
oocyte development GO:0048599 1 0.011
protein ubiquitination GO:0016567 314 0.011
regulation of cell cycle GO:0051726 393 0.011
osteoblast differentiation GO:0001649 92 0.011
regulation of cellular amino acid metabolic process GO:0006521 6 0.010
mitotic sister chromatid segregation GO:0000070 53 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010

PSMC3 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.020
eye and adnexa disease DOID:1492 150 0.020
nervous system disease DOID:863 431 0.020
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010