Homo sapiens

18 known processes

EIF3I

eukaryotic translation initiation factor 3, subunit I

(Aliases: TRIP-1,EIF3S2,eIF3-p36,PRO2242,TRIP1,eIF3-beta)

EIF3I biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 48 0.987
translation GO:0006412 132 0.942
post embryonic development GO:0009791 2 0.706
posttranscriptional regulation of gene expression GO:0010608 213 0.597
carbohydrate derivative biosynthetic process GO:1901137 207 0.517
vesicle mediated transport GO:0016192 371 0.489
ribonucleotide biosynthetic process GO:0009260 81 0.461
female gamete generation GO:0007292 2 0.446
cellular macromolecule catabolic process GO:0044265 380 0.338
oogenesis GO:0048477 2 0.329
embryo development GO:0009790 123 0.319
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.309
cell development GO:0048468 328 0.303
mitotic cell cycle process GO:1903047 286 0.287
oxidation reduction process GO:0055114 396 0.278
nucleoside triphosphate metabolic process GO:0009141 422 0.231
multicellular organismal aging GO:0010259 3 0.204
amine metabolic process GO:0009308 44 0.192
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.188
cellular lipid metabolic process GO:0044255 303 0.176
cellular response to dna damage stimulus GO:0006974 379 0.172
receptor mediated endocytosis GO:0006898 84 0.164
determination of adult lifespan GO:0008340 2 0.162
purine ribonucleoside metabolic process GO:0046128 437 0.161
nucleotide biosynthetic process GO:0009165 109 0.158
cellular amine metabolic process GO:0044106 41 0.150
positive regulation of apoptotic process GO:0043065 246 0.147
ribonucleoside triphosphate metabolic process GO:0009199 412 0.141
mitotic cell cycle GO:0000278 326 0.140
purine ribonucleoside catabolic process GO:0046130 398 0.136
nucleoside catabolic process GO:0009164 408 0.125
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.123
regulation of cellular amine metabolic process GO:0033238 11 0.123
regulation of translational initiation GO:0006446 24 0.121
rna interference GO:0016246 4 0.121
nucleoside triphosphate catabolic process GO:0009143 394 0.120
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.118
lymphocyte activation GO:0046649 133 0.116
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.114
nucleotide catabolic process GO:0009166 408 0.108
endocytosis GO:0006897 159 0.108
cytokine production GO:0001816 247 0.107
ribonucleoside monophosphate metabolic process GO:0009161 187 0.106
fatty acid metabolic process GO:0006631 115 0.102
purine nucleoside monophosphate metabolic process GO:0009126 186 0.100
organophosphate biosynthetic process GO:0090407 163 0.095
sex differentiation GO:0007548 45 0.091
nucleoside phosphate biosynthetic process GO:1901293 109 0.089
positive regulation of cellular component organization GO:0051130 376 0.089
secretion GO:0046903 254 0.086
regulation of nucleoside metabolic process GO:0009118 209 0.082
regulation of nucleotide metabolic process GO:0006140 269 0.080
positive regulation of cellular amine metabolic process GO:0033240 7 0.080
purine containing compound biosynthetic process GO:0072522 88 0.079
positive regulation of hydrolase activity GO:0051345 331 0.078
positive regulation of nucleotide metabolic process GO:0045981 230 0.077
cell activation GO:0001775 213 0.077
purine nucleoside catabolic process GO:0006152 398 0.075
blastocyst development GO:0001824 3 0.075
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.074
purine nucleotide catabolic process GO:0006195 405 0.072
reproductive system development GO:0061458 56 0.070
regulation of purine nucleotide metabolic process GO:1900542 264 0.068
negative regulation of protein metabolic process GO:0051248 391 0.067
ribonucleoside catabolic process GO:0042454 406 0.067
mrna splicing via spliceosome GO:0000398 89 0.067
purine containing compound catabolic process GO:0072523 411 0.064
regulation of lipid metabolic process GO:0019216 96 0.063
regulation of nucleotide catabolic process GO:0030811 205 0.063
regulation of cell differentiation GO:0045595 393 0.061
embryo development ending in birth or egg hatching GO:0009792 34 0.057
Worm
guanosine containing compound catabolic process GO:1901069 239 0.057
generation of neurons GO:0048699 152 0.056
reproductive structure development GO:0048608 55 0.056
cellular macromolecular complex assembly GO:0034622 324 0.054
positive regulation of developmental process GO:0051094 314 0.053
nucleocytoplasmic transport GO:0006913 176 0.052
protein maturation GO:0051604 233 0.051
regulation of multicellular organism growth GO:0040014 8 0.051
leukocyte activation GO:0045321 164 0.050
tube development GO:0035295 125 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
growth GO:0040007 202 0.049
neuron development GO:0048666 113 0.049
regulation of membrane potential GO:0042391 95 0.048
regulation of gtp catabolic process GO:0033124 180 0.048
gtp metabolic process GO:0046039 239 0.047
organonitrogen compound biosynthetic process GO:1901566 200 0.046
membrane fusion GO:0061025 43 0.046
t cell activation GO:0042110 99 0.045
cellular ketone metabolic process GO:0042180 80 0.045
single organism membrane organization GO:0044802 268 0.045
guanosine containing compound metabolic process GO:1901068 244 0.045
positive regulation of peptidase activity GO:0010952 88 0.044
apoptotic signaling pathway GO:0097190 268 0.044
developmental process involved in reproduction GO:0003006 66 0.044
regulation of translation GO:0006417 89 0.043
regulation of cell cycle process GO:0010564 266 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
reproductive process GO:0022414 106 0.043
cellular amino acid metabolic process GO:0006520 116 0.043
gtp catabolic process GO:0006184 237 0.043
response to hormone GO:0009725 175 0.042
secretion by cell GO:0032940 226 0.042
lipid localization GO:0010876 106 0.041
regulation of oxidative phosphorylation GO:0002082 3 0.041
biological adhesion GO:0022610 331 0.041
development of primary sexual characteristics GO:0045137 35 0.040
protein modification by small protein conjugation GO:0032446 342 0.040
spindle elongation GO:0051231 4 0.039
rna processing GO:0006396 255 0.039
regulation of transferase activity GO:0051338 355 0.037
cytoplasmic transport GO:0016482 379 0.037
positive regulation of cell death GO:0010942 263 0.036
multicellular organismal reproductive process GO:0048609 40 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
ubiquitin dependent protein catabolic process GO:0006511 206 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
positive regulation of cellular catabolic process GO:0031331 284 0.034
positive regulation of catabolic process GO:0009896 310 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
positive regulation of gtpase activity GO:0043547 166 0.033
toxin transport GO:1901998 4 0.033
embryonic organ development GO:0048568 36 0.033
negative regulation of cell death GO:0060548 345 0.033
maintenance of location GO:0051235 112 0.032
ribose phosphate biosynthetic process GO:0046390 82 0.032
protein ubiquitination GO:0016567 314 0.032
neurogenesis GO:0022008 169 0.032
immune response GO:0006955 307 0.032
regulation of cellular response to stress GO:0080135 244 0.031
negative regulation of programmed cell death GO:0043069 321 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.031
posttranscriptional gene silencing by rna GO:0035194 25 0.030
neuron differentiation GO:0030182 138 0.030
nitrogen compound transport GO:0071705 191 0.030
regulation of endopeptidase activity GO:0052548 170 0.029
negative regulation of intracellular signal transduction GO:1902532 183 0.029
monovalent inorganic cation transport GO:0015672 128 0.028
negative regulation of cell proliferation GO:0008285 228 0.028
rna transport GO:0050658 39 0.028
positive regulation of protein phosphorylation GO:0001934 313 0.027
gene silencing by rna GO:0031047 26 0.027
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
negative regulation of cell cycle GO:0045786 193 0.027
purine ribonucleotide biosynthetic process GO:0009152 79 0.027
mitotic cell cycle phase transition GO:0044772 162 0.027
regulation of gtpase activity GO:0043087 180 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
mrna metabolic process GO:0016071 175 0.026
organophosphate catabolic process GO:0046434 430 0.026
regulation of cell cycle GO:0051726 393 0.026
regeneration GO:0031099 4 0.026
response to wounding GO:0009611 168 0.026
centrosome organization GO:0051297 58 0.026
cell adhesion GO:0007155 325 0.026
multicellular organism reproduction GO:0032504 42 0.025
chromatin organization GO:0006325 351 0.025
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
system process GO:0003008 349 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
cell cycle phase transition GO:0044770 173 0.024
organic acid biosynthetic process GO:0016053 97 0.023
negative regulation of transport GO:0051051 176 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
single organism reproductive process GO:0044702 98 0.023
regulation of apoptotic signaling pathway GO:2001233 175 0.023
positive regulation of cellular component biogenesis GO:0044089 158 0.022
nuclear transcribed mrna catabolic process GO:0000956 48 0.022
regulation of protein localization GO:0032880 296 0.022
positive regulation of nucleotide catabolic process GO:0030813 185 0.022
chordate embryonic development GO:0043009 34 0.022
ion transmembrane transport GO:0034220 338 0.022
leukocyte proliferation GO:0070661 74 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
gene silencing GO:0016458 49 0.022
rna splicing via transesterification reactions GO:0000375 90 0.022
mrna processing GO:0006397 133 0.021
defense response GO:0006952 315 0.021
response to oxygen containing compound GO:1901700 369 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
nuclear transport GO:0051169 179 0.021
regulation of protein stability GO:0031647 87 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.021
protein acylation GO:0043543 138 0.021
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.020
response to biotic stimulus GO:0009607 276 0.020
protein dna complex subunit organization GO:0071824 80 0.020
reproduction GO:0000003 63 0.020
Worm
response to peptide hormone GO:0043434 61 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
transmembrane transport GO:0055085 399 0.020
positive regulation of proteolysis GO:0045862 142 0.019
regulation of transmembrane transport GO:0034762 139 0.019
microtubule cytoskeleton organization GO:0000226 176 0.019
protein oligomerization GO:0051259 173 0.019
single organism cell adhesion GO:0098602 179 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
protein secretion GO:0009306 98 0.019
purine nucleotide biosynthetic process GO:0006164 84 0.019
regulation of cell cycle phase transition GO:1901987 126 0.019
dna catabolic process GO:0006308 49 0.019
response to virus GO:0009615 126 0.018
epithelium development GO:0060429 227 0.018
positive regulation of programmed cell death GO:0043068 249 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
negative regulation of developmental process GO:0051093 247 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
regulation of peptidase activity GO:0052547 180 0.018
microtubule organizing center organization GO:0031023 62 0.018
regulation of immune response GO:0050776 201 0.018
protein processing GO:0016485 226 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.018
innate immune response GO:0045087 178 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
negative regulation of organelle organization GO:0010639 126 0.018
positive regulation of lipid metabolic process GO:0045834 50 0.017
regulation of growth GO:0040008 165 0.017
intracellular protein transport GO:0006886 270 0.017
regulation of mitochondrial membrane potential GO:0051881 23 0.017
regulation of cysteine type endopeptidase activity GO:2000116 127 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
microtubule based process GO:0007017 210 0.016
negative regulation of glycoprotein metabolic process GO:1903019 8 0.016
protein localization to organelle GO:0033365 280 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
cell division GO:0051301 168 0.016
atp metabolic process GO:0046034 176 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
cellular homeostasis GO:0019725 196 0.016
locomotory behavior GO:0007626 1 0.016
adult locomotory behavior GO:0008344 1 0.016
positive regulation of organelle organization GO:0010638 195 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.016
gonad development GO:0008406 34 0.015
cytoplasmic translational initiation GO:0002183 6 0.015
Yeast
regulation of defense response GO:0031347 154 0.015
regulation of kinase activity GO:0043549 314 0.015
muscle cell cellular homeostasis GO:0046716 3 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.015
regulation of leukocyte differentiation GO:1902105 61 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
sexual reproduction GO:0019953 37 0.014
negative regulation of protein modification process GO:0031400 200 0.014
response to other organism GO:0051707 261 0.014
multi organism reproductive process GO:0044703 54 0.014
glycosyl compound biosynthetic process GO:1901659 27 0.014
osteoblast differentiation GO:0001649 92 0.014
proton transport GO:0015992 22 0.014
negative regulation of transferase activity GO:0051348 124 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
cation transmembrane transport GO:0098655 238 0.014
response to external biotic stimulus GO:0043207 261 0.014
organelle assembly GO:0070925 176 0.014
defense response to other organism GO:0098542 129 0.014
rna splicing GO:0008380 131 0.014
divalent inorganic cation homeostasis GO:0072507 136 0.014
cardiovascular system development GO:0072358 262 0.014
mitochondrion organization GO:0007005 156 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
nuclear division GO:0000280 128 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
nucleic acid transport GO:0050657 39 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
hydrogen transport GO:0006818 23 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.012
glycerolipid metabolic process GO:0046486 107 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
negative regulation of cell growth GO:0030308 83 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
ribosome biogenesis GO:0042254 48 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
rna modification GO:0009451 27 0.012
ribonucleoprotein complex assembly GO:0022618 78 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
leukocyte differentiation GO:0002521 98 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
defense response to virus GO:0051607 71 0.012
regulation of binding GO:0051098 111 0.012
regulation of dna metabolic process GO:0051052 153 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
regulation of proteolysis GO:0030162 293 0.012
nervous system development GO:0007399 293 0.011
cation transport GO:0006812 331 0.011
energy coupled proton transport down electrochemical gradient GO:0015985 2 0.011
regulation of protein complex assembly GO:0043254 147 0.011
nucleoside biosynthetic process GO:0009163 26 0.011
regulation of cell adhesion GO:0030155 166 0.011
stem cell development GO:0048864 69 0.011
generation of precursor metabolites and energy GO:0006091 68 0.011
eye photoreceptor cell differentiation GO:0001754 2 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of cytokine production GO:0001817 232 0.011
divalent metal ion transport GO:0070838 152 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
regulation of oxidoreductase activity GO:0051341 43 0.011
carbohydrate metabolic process GO:0005975 207 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
gamete generation GO:0007276 25 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.011
single organism nuclear import GO:1902593 104 0.011
stem cell differentiation GO:0048863 93 0.011
ribonucleoside biosynthetic process GO:0042455 25 0.011
body morphogenesis GO:0010171 11 0.010
negative regulation of catabolic process GO:0009895 104 0.010
cellular response to hormone stimulus GO:0032870 125 0.010
rrna processing GO:0006364 35 0.010
rna 3 end processing GO:0031123 35 0.010
lipid storage GO:0019915 28 0.010
ctp metabolic process GO:0046036 1 0.010
spermatid differentiation GO:0048515 4 0.010
mammary gland morphogenesis GO:0060443 2 0.010
activation of immune response GO:0002253 114 0.010
membrane organization GO:0061024 292 0.010
cation homeostasis GO:0055080 189 0.010
immune effector process GO:0002252 159 0.010
cellular protein catabolic process GO:0044257 261 0.010

EIF3I disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.039
disease of cellular proliferation DOID:14566 174 0.039
organ system cancer DOID:0050686 164 0.018
parkinson s disease DOID:14330 18 0.017
synucleinopathy DOID:0050890 22 0.017
central nervous system disease DOID:331 186 0.017
neurodegenerative disease DOID:1289 102 0.017
nervous system disease DOID:863 431 0.017