Homo sapiens

19 known processes

PGCP

plasma glutamate carboxypeptidase

PGCP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation via mhc class ib GO:0002475 3 0.197
response to external biotic stimulus GO:0043207 261 0.170
post embryonic development GO:0009791 2 0.143
response to other organism GO:0051707 261 0.141
innate immune response GO:0045087 178 0.116
response to bacterium GO:0009617 144 0.114
response to wounding GO:0009611 168 0.109
Rat
detection of external biotic stimulus GO:0098581 19 0.099
negative regulation of protein metabolic process GO:0051248 391 0.089
negative regulation of multicellular organismal process GO:0051241 317 0.083
response to biotic stimulus GO:0009607 276 0.080
regulation of secretion by cell GO:1903530 177 0.079
regulation of cytokine production GO:0001817 232 0.078
detection of chemical stimulus GO:0009593 55 0.072
defense response GO:0006952 315 0.071
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.070
determination of adult lifespan GO:0008340 2 0.068
epidermis morphogenesis GO:0048730 3 0.068
cellular ketone metabolic process GO:0042180 80 0.057
regulation of secretion GO:0051046 194 0.054
glycoprotein metabolic process GO:0009100 110 0.049
regulation of defense response GO:0031347 154 0.049
regulation of epithelial cell proliferation GO:0050678 113 0.048
wound healing GO:0042060 115 0.047
Rat
multicellular organismal homeostasis GO:0048871 67 0.044
immune response GO:0006955 307 0.044
negative regulation of developmental process GO:0051093 247 0.043
circulatory system development GO:0072359 262 0.043
negative regulation of cell proliferation GO:0008285 228 0.042
sensory perception of taste GO:0050909 36 0.042
lipid metabolic process GO:0006629 381 0.042
mapk cascade GO:0000165 288 0.042
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.042
regulation of cell differentiation GO:0045595 393 0.042
sensory perception of bitter taste GO:0050913 28 0.041
positive regulation of phosphorylation GO:0042327 394 0.041
regulation of innate immune response GO:0045088 97 0.041
sensory perception of chemical stimulus GO:0007606 38 0.041
vesicle organization GO:0016050 62 0.040
multicellular organismal aging GO:0010259 3 0.040
vasculature development GO:0001944 181 0.040
immune effector process GO:0002252 159 0.038
epithelial cell proliferation GO:0050673 128 0.037
detection of stimulus GO:0051606 85 0.036
response to caffeine GO:0031000 3 0.035
positive regulation of immune response GO:0050778 159 0.035
cellular macromolecule catabolic process GO:0044265 380 0.035
anatomical structure homeostasis GO:0060249 100 0.034
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.033
negative regulation of defense response GO:0031348 47 0.033
response to hormone GO:0009725 175 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.032
positive regulation of aldosterone metabolic process GO:0032346 2 0.032
regulation of transferase activity GO:0051338 355 0.032
protein maturation GO:0051604 233 0.032
positive regulation of catabolic process GO:0009896 310 0.031
blood vessel morphogenesis GO:0048514 162 0.031
negative regulation of cell motility GO:2000146 104 0.031
negative regulation of cellular protein metabolic process GO:0032269 353 0.031
regulation of immune response GO:0050776 201 0.031
positive regulation of secretion by cell GO:1903532 108 0.031
tissue homeostasis GO:0001894 63 0.030
regulation of cell motility GO:2000145 299 0.030
positive regulation of transport GO:0051050 336 0.029
regulation of protein kinase activity GO:0045859 289 0.029
regulation of protein localization GO:0032880 296 0.029
exocytosis GO:0006887 71 0.029
positive regulation of cellular component organization GO:0051130 376 0.028
response to oxygen levels GO:0070482 100 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
cellular hormone metabolic process GO:0034754 41 0.028
positive regulation of organelle organization GO:0010638 195 0.028
response to abiotic stimulus GO:0009628 336 0.028
cellular amino acid metabolic process GO:0006520 116 0.028
Rat
apoptotic signaling pathway GO:0097190 268 0.028
vesicle mediated transport GO:0016192 371 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
regulation of protein maturation GO:1903317 150 0.027
protein catabolic process GO:0030163 325 0.027
positive regulation of defense response GO:0031349 87 0.027
positive regulation of cell differentiation GO:0045597 211 0.027
positive regulation of cytokine production GO:0001819 167 0.026
response to oxygen containing compound GO:1901700 369 0.026
protein localization to organelle GO:0033365 280 0.026
wnt signaling pathway GO:0016055 156 0.026
response to organic cyclic compound GO:0014070 204 0.026
regulation of exocytosis GO:0017157 46 0.026
cellular response to oxygen containing compound GO:1901701 276 0.026
ameboidal type cell migration GO:0001667 135 0.025
cellular amine metabolic process GO:0044106 41 0.025
negative regulation of dendritic cell differentiation GO:2001199 2 0.025
detection of biotic stimulus GO:0009595 21 0.025
secretion GO:0046903 254 0.025
oogenesis GO:0048477 2 0.025
regulation of establishment of protein localization GO:0070201 242 0.024
nucleoside phosphate catabolic process GO:1901292 412 0.024
epithelium migration GO:0090132 119 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
cation transport GO:0006812 331 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
metal ion transport GO:0030001 272 0.024
regulation of wound healing GO:0061041 56 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.023
positive regulation of innate immune response GO:0045089 79 0.023
cell adhesion GO:0007155 325 0.023
positive regulation of immune system process GO:0002684 283 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
rho protein signal transduction GO:0007266 26 0.022
cell development GO:0048468 328 0.022
negative regulation of proteolysis GO:0045861 132 0.022
monocarboxylic acid metabolic process GO:0032787 185 0.022
protein processing GO:0016485 226 0.022
positive regulation of exocytosis GO:0045921 35 0.022
positive regulation of transferase activity GO:0051347 227 0.022
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
positive regulation of exosomal secretion GO:1903543 12 0.022
positive regulation of secretion GO:0051047 116 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
cellular response to nutrient levels GO:0031669 69 0.021
cell morphogenesis GO:0000902 296 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of cellular response to stress GO:0080135 244 0.021
negative regulation of vasculature development GO:1901343 43 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
regulation of exosomal secretion GO:1903541 12 0.021
system process GO:0003008 349 0.021
response to hypoxia GO:0001666 96 0.021
negative regulation of protein maturation GO:1903318 142 0.020
negative regulation of immune system process GO:0002683 136 0.020
positive regulation of kinase activity GO:0033674 204 0.020
segmentation GO:0035282 4 0.020
hemopoiesis GO:0030097 180 0.020
purine nucleoside catabolic process GO:0006152 398 0.020
intracellular protein transport GO:0006886 270 0.020
regulation of protein processing GO:0070613 150 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
growth GO:0040007 202 0.020
Rat
regulation of actin cytoskeleton organization GO:0032956 116 0.020
secretion by cell GO:0032940 226 0.020
positive regulation of cellular component biogenesis GO:0044089 158 0.019
retina homeostasis GO:0001895 42 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.019
response to purine containing compound GO:0014074 40 0.019
regulation of immune effector process GO:0002697 91 0.019
regulation of protein transport GO:0051223 213 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
regulation of cellular response to growth factor stimulus GO:0090287 76 0.019
blood vessel development GO:0001568 172 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
mating GO:0007618 1 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
regulation of proteolysis GO:0030162 293 0.018
regulation of epithelial cell migration GO:0010632 93 0.018
cytokine production GO:0001816 247 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
female gamete generation GO:0007292 2 0.018
epithelium development GO:0060429 227 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
transition metal ion transport GO:0000041 23 0.018
organophosphate catabolic process GO:0046434 430 0.017
purine containing compound catabolic process GO:0072523 411 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
response to organonitrogen compound GO:0010243 156 0.017
regulation of glycoprotein metabolic process GO:1903018 19 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
cellular response to extracellular stimulus GO:0031668 72 0.017
protein ubiquitination GO:0016567 314 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
single organism cellular localization GO:1902580 332 0.017
generation of neurons GO:0048699 152 0.017
regulation of peptidase activity GO:0052547 180 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of mapk cascade GO:0043408 262 0.017
inflammatory response GO:0006954 79 0.017
amine metabolic process GO:0009308 44 0.017
regulation of protein catabolic process GO:0042176 155 0.017
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.017
protein activation cascade GO:0072376 22 0.017
cardiovascular system development GO:0072358 262 0.017
cellular component morphogenesis GO:0032989 314 0.017
blood circulation GO:0008015 113 0.017
single organism membrane organization GO:0044802 268 0.016
cell growth GO:0016049 160 0.016
cellular protein catabolic process GO:0044257 261 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
negative regulation of blood pressure GO:0045776 3 0.016
steroid metabolic process GO:0008202 94 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
endothelial cell migration GO:0043542 86 0.016
cell activation GO:0001775 213 0.016
regeneration GO:0031099 4 0.016
Rat
nervous system development GO:0007399 293 0.016
regulation of protein stability GO:0031647 87 0.016
alcohol metabolic process GO:0006066 114 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
angiogenesis GO:0001525 147 0.016
regulation of cell migration GO:0030334 289 0.016
neurological system process GO:0050877 163 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
positive regulation of lymphocyte activation GO:0051251 73 0.015
cytoplasmic transport GO:0016482 379 0.015
cell projection organization GO:0030030 252 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of cell cycle GO:0051726 393 0.015
negative regulation of glycoprotein metabolic process GO:1903019 8 0.015
regulation of organelle assembly GO:1902115 40 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
regulation of response to external stimulus GO:0032101 222 0.015
immune response regulating signaling pathway GO:0002764 97 0.015
regulation of cellular component movement GO:0051270 334 0.015
response to axon injury GO:0048678 1 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
plasma membrane organization GO:0007009 115 0.015
blood coagulation GO:0007596 76 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
negative regulation of trophoblast cell migration GO:1901164 3 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
regulation of tolerance induction GO:0002643 4 0.015
immune system development GO:0002520 195 0.014
actin filament based process GO:0030029 224 0.014
cell part morphogenesis GO:0032990 137 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
negative regulation of protein processing GO:0010955 142 0.014
actin mediated cell contraction GO:0070252 12 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
peripheral nervous system development GO:0007422 2 0.014
intracellular receptor signaling pathway GO:0030522 104 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
negative regulation of catabolic process GO:0009895 104 0.014
regulation of dendritic cell differentiation GO:2001198 3 0.014
positive regulation of endothelial cell migration GO:0010595 39 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
nuclear transport GO:0051169 179 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
response to nitrogen compound GO:1901698 184 0.014
natural killer cell mediated immunity GO:0002228 23 0.014
sulfur compound metabolic process GO:0006790 101 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
exosomal secretion GO:1990182 15 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of angiogenesis GO:0045765 92 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
positive regulation of regulatory t cell differentiation GO:0045591 3 0.013
positive regulation of cell motility GO:2000147 177 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
negative regulation of immune response GO:0050777 40 0.013
mitotic cell cycle GO:0000278 326 0.013
regulation of interferon gamma production GO:0032649 36 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
actin filament based movement GO:0030048 17 0.013
lipid biosynthetic process GO:0008610 177 0.013
regulation of actin filament based process GO:0032970 141 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
sensory perception GO:0007600 103 0.013
defense response to other organism GO:0098542 129 0.013
interferon gamma production GO:0032609 39 0.013
response to calcium ion GO:0051592 46 0.013
tissue morphogenesis GO:0048729 96 0.013
neurogenesis GO:0022008 169 0.013
cation homeostasis GO:0055080 189 0.013
cellular component disassembly GO:0022411 92 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
carbohydrate metabolic process GO:0005975 207 0.013
cellular response to external stimulus GO:0071496 111 0.013
cellular modified amino acid metabolic process GO:0006575 64 0.013
Rat
leukocyte activation GO:0045321 164 0.013
regulation of intracellular transport GO:0032386 195 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of cell projection organization GO:0031344 107 0.012
regulation of extracellular vesicular exosome assembly GO:1903551 4 0.012
defense response to bacterium GO:0042742 63 0.012
negative regulation of blood vessel morphogenesis GO:2000181 41 0.012
natural killer cell activation involved in immune response GO:0002323 2 0.012
nucleotide catabolic process GO:0009166 408 0.012
ras protein signal transduction GO:0007265 73 0.012
epithelial cell migration GO:0010631 119 0.012
positive regulation of leukocyte activation GO:0002696 80 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
response to virus GO:0009615 126 0.012
regulation of regulatory t cell differentiation GO:0045589 4 0.012
gtp metabolic process GO:0046039 239 0.012
cellular lipid metabolic process GO:0044255 303 0.012
response to extracellular stimulus GO:0009991 85 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.012
memory GO:0007613 3 0.012
epithelial cell differentiation GO:0030855 141 0.012
positive regulation of lymphocyte differentiation GO:0045621 13 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of multi organism process GO:0043900 157 0.012
negative regulation of immune effector process GO:0002698 38 0.012
cellular response to reactive oxygen species GO:0034614 50 0.012
regulation of body fluid levels GO:0050878 99 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
multi organism cellular process GO:0044764 156 0.012
actin cytoskeleton organization GO:0030036 207 0.012
establishment of tissue polarity GO:0007164 3 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
regulation of cell adhesion GO:0030155 166 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
ossification GO:0001503 121 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of kinase activity GO:0043549 314 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.011
prostate gland development GO:0030850 3 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
response to decreased oxygen levels GO:0036293 96 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
protein stabilization GO:0050821 64 0.011
long term memory GO:0007616 2 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
peptide metabolic process GO:0006518 51 0.011
humoral immune response GO:0006959 49 0.011
regulation of leukocyte differentiation GO:1902105 61 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
coagulation GO:0050817 78 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
tissue migration GO:0090130 119 0.011
tripartite regional subdivision GO:0007351 2 0.011
response to lipid GO:0033993 206 0.011
neuromuscular junction development GO:0007528 3 0.011
response to inorganic substance GO:0010035 127 0.011
endomembrane system organization GO:0010256 196 0.011
response to cytokine GO:0034097 232 0.011
organelle assembly GO:0070925 176 0.011
negative regulation of cell migration GO:0030336 102 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
regulation of endothelial cell proliferation GO:0001936 56 0.011
regulation of vasculature development GO:1901342 97 0.011
cellular response to lipid GO:0071396 127 0.011
cell substrate adhesion GO:0031589 132 0.011
diterpenoid metabolic process GO:0016101 20 0.011
isoprenoid metabolic process GO:0006720 39 0.011
regulation of locomotion GO:0040012 329 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
chemical homeostasis GO:0048878 306 0.011
pharyngeal system development GO:0060037 2 0.011
negative regulation of peptidase activity GO:0010466 91 0.011
cellular protein complex assembly GO:0043623 188 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
negative regulation of angiogenesis GO:0016525 39 0.011
oocyte differentiation GO:0009994 2 0.011
regulation of natural killer cell mediated immunity GO:0002715 16 0.010
regulation of neurogenesis GO:0050767 82 0.010
cell division GO:0051301 168 0.010
endosomal transport GO:0016197 129 0.010
tissue regeneration GO:0042246 3 0.010
Rat
maintenance of location GO:0051235 112 0.010
regulation of protein secretion GO:0050708 86 0.010
lymphocyte mediated immunity GO:0002449 48 0.010
spermatid differentiation GO:0048515 4 0.010
reproductive process GO:0022414 106 0.010
protein localization to membrane GO:0072657 160 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
establishment of planar polarity GO:0001736 3 0.010
energy homeostasis GO:0097009 3 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
cellular amide metabolic process GO:0043603 69 0.010
cell projection morphogenesis GO:0048858 129 0.010
protein targeting GO:0006605 187 0.010

PGCP disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.674
inherited metabolic disorder DOID:655 242 0.476
lysosomal storage disease DOID:3211 47 0.071
musculoskeletal system disease DOID:17 223 0.038
connective tissue disease DOID:65 109 0.038
acquired metabolic disease DOID:0060158 58 0.031
cerebral degeneration DOID:1443 16 0.030
central nervous system disease DOID:331 186 0.030
brain disease DOID:936 73 0.030
nervous system disease DOID:863 431 0.030
sensory system disease DOID:0050155 203 0.029
lipid storage disease DOID:9455 28 0.028
eye and adnexa disease DOID:1492 150 0.025
eye disease DOID:5614 149 0.025
retinal disease DOID:5679 118 0.015
retinal degeneration DOID:8466 89 0.013
immune system disease DOID:2914 155 0.012
disease of cellular proliferation DOID:14566 174 0.010
cancer DOID:162 167 0.010
osteochondrodysplasia DOID:2256 35 0.010
bone development disease DOID:0080006 55 0.010
bone disease DOID:0080001 88 0.010