Homo sapiens

31 known processes

EIF3A

eukaryotic translation initiation factor 3, subunit A

(Aliases: p185,eIF3-p170,eIF3-theta,EIF3,P167,EIF3S10,KIAA0139,p180,TIF32)

EIF3A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 48 1.000
female gamete generation GO:0007292 2 0.933
mrna metabolic process GO:0016071 175 0.913
cytoplasmic translational initiation GO:0002183 6 0.904
translation GO:0006412 132 0.828
protein modification by small protein removal GO:0070646 92 0.772
protein deubiquitination GO:0016579 79 0.765
post embryonic development GO:0009791 2 0.638
Worm
cell cycle phase transition GO:0044770 173 0.637
rna processing GO:0006396 255 0.615
determination of adult lifespan GO:0008340 2 0.530
Worm
cellular response to dna damage stimulus GO:0006974 379 0.513
negative regulation of protein processing GO:0010955 142 0.433
regulation of proteolysis GO:0030162 293 0.425
receptor mediated endocytosis GO:0006898 84 0.381
Worm
protein modification by small protein conjugation GO:0032446 342 0.369
negative regulation of protein maturation GO:1903318 142 0.369
multicellular organismal aging GO:0010259 3 0.354
Worm
memory GO:0007613 3 0.341
neuron projection development GO:0031175 106 0.328
cellular amino acid metabolic process GO:0006520 116 0.309
oogenesis GO:0048477 2 0.304
oocyte differentiation GO:0009994 2 0.290
single organism cellular localization GO:1902580 332 0.281
embryo development GO:0009790 123 0.269
Worm
regulation of protein maturation GO:1903317 150 0.264
spermatid development GO:0007286 4 0.256
dna repair GO:0006281 198 0.256
cardiovascular system development GO:0072358 262 0.237
reproduction GO:0000003 63 0.235
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.235
mitotic cell cycle phase transition GO:0044772 162 0.234
amine metabolic process GO:0009308 44 0.234
oocyte development GO:0048599 1 0.217
regulation of cell cycle process GO:0010564 266 0.216
regulation of cellular amino acid metabolic process GO:0006521 6 0.216
reproductive process GO:0022414 106 0.213
Worm
purine nucleoside monophosphate catabolic process GO:0009128 158 0.211
developmental growth GO:0048589 48 0.205
posttranscriptional regulation of gene expression GO:0010608 213 0.194
cell development GO:0048468 328 0.189
cellular amine metabolic process GO:0044106 41 0.188
spermatid differentiation GO:0048515 4 0.184
regulation of translational initiation GO:0006446 24 0.181
cell division GO:0051301 168 0.171
cellular ketone metabolic process GO:0042180 80 0.171
embryonic morphogenesis GO:0048598 85 0.170
mitotic cell cycle GO:0000278 326 0.165
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.158
mrna processing GO:0006397 133 0.154
rna catabolic process GO:0006401 71 0.154
protein processing GO:0016485 226 0.153
endocytosis GO:0006897 159 0.148
Worm
ribonucleoside monophosphate metabolic process GO:0009161 187 0.148
cellular macromolecule catabolic process GO:0044265 380 0.136
golgi organization GO:0007030 38 0.134
lipid localization GO:0010876 106 0.133
formation of translation preinitiation complex GO:0001731 4 0.132
nuclear division GO:0000280 128 0.132
protein maturation GO:0051604 233 0.130
nucleoside monophosphate catabolic process GO:0009125 159 0.127
regulation of cell cycle GO:0051726 393 0.126
regulation of protein processing GO:0070613 150 0.125
developmental process involved in reproduction GO:0003006 66 0.115
regulation of translation GO:0006417 89 0.113
nuclear transcribed mrna catabolic process GO:0000956 48 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.111
mrna catabolic process GO:0006402 56 0.107
regulation of cysteine type endopeptidase activity GO:2000116 127 0.106
sister chromatid segregation GO:0000819 54 0.104
neuron differentiation GO:0030182 138 0.101
embryo development ending in birth or egg hatching GO:0009792 34 0.099
Worm
vesicle mediated transport GO:0016192 371 0.098
Worm
positive regulation of proteolysis GO:0045862 142 0.095
ribonucleoprotein complex assembly GO:0022618 78 0.095
multicellular organismal reproductive process GO:0048609 40 0.094
Worm
single organism reproductive process GO:0044702 98 0.093
regulation of endopeptidase activity GO:0052548 170 0.093
maintenance of location GO:0051235 112 0.090
innate immune response GO:0045087 178 0.088
protein localization to organelle GO:0033365 280 0.088
generation of neurons GO:0048699 152 0.086
regulation of cell cycle phase transition GO:1901987 126 0.085
regulation of cellular amine metabolic process GO:0033238 11 0.082
sex differentiation GO:0007548 45 0.081
chromatin organization GO:0006325 351 0.081
organelle fission GO:0048285 149 0.080
regulation of apoptotic signaling pathway GO:2001233 175 0.079
stem cell differentiation GO:0048863 93 0.078
ribosomal small subunit biogenesis GO:0042274 13 0.077
regulation of cell division GO:0051302 116 0.076
rna interference GO:0016246 4 0.075
negative regulation of catalytic activity GO:0043086 335 0.075
negative regulation of proteolysis GO:0045861 132 0.074
gonad development GO:0008406 34 0.071
endomembrane system organization GO:0010256 196 0.071
purine ribonucleoside catabolic process GO:0046130 398 0.071
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.070
mitotic nuclear division GO:0007067 119 0.070
tube development GO:0035295 125 0.068
stem cell development GO:0048864 69 0.068
cell morphogenesis GO:0000902 296 0.066
ribonucleoprotein complex subunit organization GO:0071826 81 0.063
system process GO:0003008 349 0.061
regulation of peptidase activity GO:0052547 180 0.060
cell projection organization GO:0030030 252 0.059
regulation of cellular ketone metabolic process GO:0010565 50 0.059
negative regulation of cell death GO:0060548 345 0.058
anatomical structure formation involved in morphogenesis GO:0048646 284 0.058
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.058
negative regulation of chromosome organization GO:2001251 48 0.058
negative regulation of cell cycle process GO:0010948 121 0.057
negative regulation of peptidase activity GO:0010466 91 0.057
circulatory system development GO:0072359 262 0.057
regulation of chromosome segregation GO:0051983 44 0.057
protein ubiquitination GO:0016567 314 0.055
embryonic organ development GO:0048568 36 0.054
long term memory GO:0007616 2 0.054
regulation of mrna metabolic process GO:1903311 53 0.054
neural tube formation GO:0001841 3 0.054
regulation of protein ubiquitination GO:0031396 95 0.054
regulation of meiotic cell cycle GO:0051445 4 0.052
neuron development GO:0048666 113 0.051
nervous system development GO:0007399 293 0.049
positive regulation of peptidase activity GO:0010952 88 0.048
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.048
multi organism reproductive process GO:0044703 54 0.046
Worm
positive regulation of transport GO:0051050 336 0.046
regulation of protein localization GO:0032880 296 0.045
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.045
reproductive structure development GO:0048608 55 0.045
immune response GO:0006955 307 0.044
cell part morphogenesis GO:0032990 137 0.042
positive regulation of cellular component organization GO:0051130 376 0.041
regulation of chromosome organization GO:0033044 103 0.040
mitotic cell cycle process GO:1903047 286 0.040
Fly
neuron projection morphogenesis GO:0048812 50 0.040
multicellular organism reproduction GO:0032504 42 0.040
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.038
ribonucleoside catabolic process GO:0042454 406 0.037
regulation of protein complex assembly GO:0043254 147 0.037
reproductive system development GO:0061458 56 0.037
rna splicing GO:0008380 131 0.035
purine nucleoside monophosphate metabolic process GO:0009126 186 0.035
neurogenesis GO:0022008 169 0.035
atp catabolic process GO:0006200 157 0.034
intracellular mrna localization GO:0008298 1 0.034
positive regulation of growth GO:0045927 58 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
regulation of nuclear division GO:0051783 65 0.034
nuclear transcribed mrna catabolic process exonucleolytic GO:0000291 7 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
regulation of mitosis GO:0007088 63 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
regulation of cell growth GO:0001558 135 0.033
purine containing compound catabolic process GO:0072523 411 0.033
nucleoside catabolic process GO:0009164 408 0.033
negative regulation of protein metabolic process GO:0051248 391 0.033
organ morphogenesis GO:0009887 147 0.032
cellular component morphogenesis GO:0032989 314 0.032
negative regulation of binding GO:0051100 57 0.032
mesenchymal cell differentiation GO:0048762 52 0.032
centrosome organization GO:0051297 58 0.032
tube morphogenesis GO:0035239 95 0.032
negative regulation of dna metabolic process GO:0051053 57 0.031
chromosome segregation GO:0007059 114 0.031
nucleotide catabolic process GO:0009166 408 0.031
protein localization to membrane GO:0072657 160 0.031
dorsal ventral axis specification GO:0009950 7 0.031
growth GO:0040007 202 0.031
positive regulation of hydrolase activity GO:0051345 331 0.030
protein targeting GO:0006605 187 0.030
dorsal ventral pattern formation GO:0009953 15 0.030
angiogenesis GO:0001525 147 0.029
embryonic epithelial tube formation GO:0001838 4 0.029
modification dependent macromolecule catabolic process GO:0043632 212 0.028
apoptotic signaling pathway GO:0097190 268 0.028
atp metabolic process GO:0046034 176 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
regulation of dna metabolic process GO:0051052 153 0.028
protein secretion GO:0009306 98 0.027
spindle organization GO:0007051 53 0.026
Fly
epithelium development GO:0060429 227 0.026
negative regulation of cell cycle GO:0045786 193 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
regulation of chromatin modification GO:1903308 51 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
defense response GO:0006952 315 0.026
covalent chromatin modification GO:0016569 254 0.026
primary neural tube formation GO:0014020 3 0.025
sexual reproduction GO:0019953 37 0.025
metaphase anaphase transition of cell cycle GO:0044784 21 0.025
mrna splicing via spliceosome GO:0000398 89 0.025
regionalization GO:0003002 29 0.025
skeletal muscle tissue growth GO:0048630 2 0.024
g1 s transition of mitotic cell cycle GO:0000082 78 0.024
lipid storage GO:0019915 28 0.024
golgi vesicle transport GO:0048193 80 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
modification dependent protein catabolic process GO:0019941 209 0.023
organophosphate catabolic process GO:0046434 430 0.023
response to external biotic stimulus GO:0043207 261 0.023
cellular response to molecule of bacterial origin GO:0071219 62 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
neural crest cell development GO:0014032 3 0.021
organelle localization GO:0051640 84 0.021
negative regulation of cellular catabolic process GO:0031330 83 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
cell projection morphogenesis GO:0048858 129 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
cellular amide metabolic process GO:0043603 69 0.020
regulation of sister chromatid segregation GO:0033045 27 0.020
intracellular protein transport GO:0006886 270 0.020
protein autophosphorylation GO:0046777 123 0.019
protein catabolic process GO:0030163 325 0.019
autophagic cell death GO:0048102 3 0.019
blood vessel morphogenesis GO:0048514 162 0.018
rna splicing via transesterification reactions GO:0000375 90 0.018
dna conformation change GO:0071103 113 0.018
cellular response to abiotic stimulus GO:0071214 117 0.018
response to cytokine GO:0034097 232 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.018
positive regulation of developmental growth GO:0048639 16 0.018
regulation of mitotic sister chromatid separation GO:0010965 27 0.017
somitogenesis GO:0001756 2 0.017
negative regulation of dna replication GO:0008156 29 0.017
protein homooligomerization GO:0051260 100 0.017
ncrna metabolic process GO:0034660 108 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
negative regulation of protein modification process GO:0031400 200 0.017
positive regulation of organelle organization GO:0010638 195 0.017
single organism nuclear import GO:1902593 104 0.017
negative regulation of cell cycle phase transition GO:1901988 89 0.017
regulation of binding GO:0051098 111 0.017
heart development GO:0007507 95 0.017
peptidyl tyrosine modification GO:0018212 170 0.016
regulation of growth GO:0040008 165 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
activation of cysteine type endopeptidase activity GO:0097202 57 0.016
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.016
cell cycle checkpoint GO:0000075 117 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
regeneration GO:0031099 4 0.015
negative regulation of cell growth GO:0030308 83 0.015
negative regulation of protein ubiquitination GO:0031397 35 0.015
cell cycle g1 s phase transition GO:0044843 80 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
positive regulation of intracellular protein transport GO:0090316 76 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
neural tube closure GO:0001843 3 0.015
chordate embryonic development GO:0043009 34 0.015
negative regulation of hydrolase activity GO:0051346 182 0.014
cell growth GO:0016049 160 0.014
nucleus organization GO:0006997 28 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.014
mitotic sister chromatid segregation GO:0000070 53 0.013
dephosphorylation GO:0016311 209 0.013
cellular protein catabolic process GO:0044257 261 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
eye development GO:0001654 42 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
regulation of protein stability GO:0031647 87 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
cytoplasmic transport GO:0016482 379 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
tube closure GO:0060606 3 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
response to inorganic substance GO:0010035 127 0.012
negative regulation of cell development GO:0010721 48 0.012
positive regulation of response to external stimulus GO:0032103 88 0.012
positive regulation of developmental process GO:0051094 314 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
posttranscriptional gene silencing by rna GO:0035194 25 0.011
ribonucleoprotein complex localization GO:0071166 4 0.011
cytokinesis GO:0000910 96 0.011
digestive system development GO:0055123 75 0.011
embryonic organ morphogenesis GO:0048562 24 0.011
positive regulation of protein transport GO:0051222 135 0.011
mitotic sister chromatid separation GO:0051306 18 0.011
compound eye development GO:0048749 1 0.011
positive regulation of protein localization to nucleus GO:1900182 48 0.011
microtubule based process GO:0007017 210 0.011
Fly
anterior posterior axis specification GO:0009948 2 0.011
secretion GO:0046903 254 0.011
regulation of meiosis GO:0040020 3 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.010
positive regulation of cytoplasmic transport GO:1903651 82 0.010
positive regulation of cell death GO:0010942 263 0.010
response to other organism GO:0051707 261 0.010
wound healing GO:0042060 115 0.010
sensory organ development GO:0007423 52 0.010

EIF3A disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.017
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012