Homo sapiens

35 known processes

EIF3B

eukaryotic translation initiation factor 3, subunit B

(Aliases: MGC131875,PRT1,EIF3S9,EIF3-P116,MGC104664,EIF3-P110,EIF3-ETA)

EIF3B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 48 1.000
cytoplasmic translational initiation GO:0002183 6 1.000
translation GO:0006412 132 0.981
post embryonic development GO:0009791 2 0.943
Worm
mrna catabolic process GO:0006402 56 0.926
rna processing GO:0006396 255 0.914
rrna processing GO:0006364 35 0.886
ncrna metabolic process GO:0034660 108 0.831
posttranscriptional regulation of gene expression GO:0010608 213 0.797
female gamete generation GO:0007292 2 0.792
mrna metabolic process GO:0016071 175 0.732
multicellular organismal aging GO:0010259 3 0.670
Worm
regulation of translation GO:0006417 89 0.591
vesicle mediated transport GO:0016192 371 0.578
Worm
oogenesis GO:0048477 2 0.557
ribonucleoside catabolic process GO:0042454 406 0.500
rrna metabolic process GO:0016072 40 0.467
ribonucleoprotein complex biogenesis GO:0022613 116 0.464
ribosome biogenesis GO:0042254 48 0.425
reproductive process GO:0022414 106 0.417
rna catabolic process GO:0006401 71 0.388
oocyte differentiation GO:0009994 2 0.378
amine metabolic process GO:0009308 44 0.338
cell development GO:0048468 328 0.316
Zebrafish
ribosomal small subunit biogenesis GO:0042274 13 0.300
mitotic cell cycle process GO:1903047 286 0.265
mitotic cell cycle GO:0000278 326 0.264
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.256
nuclear transcribed mrna catabolic process GO:0000956 48 0.254
regulation of endopeptidase activity GO:0052548 170 0.236
embryo development GO:0009790 123 0.231
Zebrafish Worm
cellular response to dna damage stimulus GO:0006974 379 0.230
mrna splicing via spliceosome GO:0000398 89 0.224
rna interference GO:0016246 4 0.219
ribonucleoside monophosphate metabolic process GO:0009161 187 0.212
reproduction GO:0000003 63 0.183
Worm
regulation of translational initiation GO:0006446 24 0.181
cytoplasmic transport GO:0016482 379 0.162
mrna processing GO:0006397 133 0.159
nucleoside catabolic process GO:0009164 408 0.147
regulation of mrna splicing via spliceosome GO:0048024 32 0.145
regulation of mrna metabolic process GO:1903311 53 0.144
determination of adult lifespan GO:0008340 2 0.142
Worm
regulation of cell cycle GO:0051726 393 0.139
endocytosis GO:0006897 159 0.139
Worm
neuron projection development GO:0031175 106 0.131
oocyte development GO:0048599 1 0.121
nucleoside triphosphate metabolic process GO:0009141 422 0.118
generation of neurons GO:0048699 152 0.114
dna replication GO:0006260 116 0.112
rna splicing GO:0008380 131 0.110
nucleotide catabolic process GO:0009166 408 0.108
single organism cellular localization GO:1902580 332 0.102
purine nucleoside monophosphate catabolic process GO:0009128 158 0.100
primary mirna processing GO:0031053 3 0.098
developmental process involved in reproduction GO:0003006 66 0.097
glycosyl compound catabolic process GO:1901658 413 0.092
cellular macromolecule catabolic process GO:0044265 380 0.088
rna splicing via transesterification reactions GO:0000375 90 0.088
purine nucleoside monophosphate metabolic process GO:0009126 186 0.087
cellular macromolecular complex assembly GO:0034622 324 0.086
covalent chromatin modification GO:0016569 254 0.086
sex differentiation GO:0007548 45 0.084
positive regulation of hydrolase activity GO:0051345 331 0.080
chromatin organization GO:0006325 351 0.079
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.079
regulation of chromosome organization GO:0033044 103 0.076
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.073
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.071
cellular amine metabolic process GO:0044106 41 0.070
neurogenesis GO:0022008 169 0.070
reproductive system development GO:0061458 56 0.065
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.063
purine ribonucleotide catabolic process GO:0009154 404 0.062
regulation of rna splicing GO:0043484 62 0.061
ribonucleoside monophosphate catabolic process GO:0009158 158 0.058
blastocyst development GO:0001824 3 0.057
mitotic cell cycle phase transition GO:0044772 162 0.056
regulation of mrna processing GO:0050684 48 0.055
ribonucleoprotein complex assembly GO:0022618 78 0.053
regulation of growth GO:0040008 165 0.053
organophosphate catabolic process GO:0046434 430 0.050
purine nucleoside catabolic process GO:0006152 398 0.050
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.049
embryo development ending in birth or egg hatching GO:0009792 34 0.048
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
receptor mediated endocytosis GO:0006898 84 0.046
Worm
neuron differentiation GO:0030182 138 0.045
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.045
nuclear transport GO:0051169 179 0.044
nucleoside triphosphate catabolic process GO:0009143 394 0.042
multi organism reproductive process GO:0044703 54 0.042
positive regulation of translation GO:0045727 35 0.041
nuclear export GO:0051168 69 0.041
purine ribonucleoside catabolic process GO:0046130 398 0.041
maturation of lsu rrna GO:0000470 3 0.041
viral life cycle GO:0019058 132 0.041
neuron development GO:0048666 113 0.040
dephosphorylation GO:0016311 209 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
reproductive structure development GO:0048608 55 0.039
ribonucleoside triphosphate catabolic process GO:0009203 391 0.038
single organism reproductive process GO:0044702 98 0.038
spindle elongation GO:0051231 4 0.038
viral process GO:0016032 146 0.037
ribonucleotide catabolic process GO:0009261 405 0.036
system process GO:0003008 349 0.035
multicellular organismal reproductive process GO:0048609 40 0.035
regulation of meiotic cell cycle GO:0051445 4 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.034
purine containing compound catabolic process GO:0072523 411 0.034
posttranscriptional gene silencing by rna GO:0035194 25 0.033
nucleocytoplasmic transport GO:0006913 176 0.033
nucleoside monophosphate catabolic process GO:0009125 159 0.032
cell cycle phase transition GO:0044770 173 0.032
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.031
g1 s transition of mitotic cell cycle GO:0000082 78 0.030
multi organism cellular process GO:0044764 156 0.029
regulation of meiosis GO:0040020 3 0.029
histone acetylation GO:0016573 93 0.028
gonad development GO:0008406 34 0.028
spermatid differentiation GO:0048515 4 0.028
production of small rna involved in gene silencing by rna GO:0070918 13 0.027
gene silencing by rna GO:0031047 26 0.027
chordate embryonic development GO:0043009 34 0.026
negative regulation of viral process GO:0048525 66 0.026
atp catabolic process GO:0006200 157 0.025
sexual reproduction GO:0019953 37 0.025
eye photoreceptor cell differentiation GO:0001754 2 0.025
ribonucleoprotein complex subunit organization GO:0071826 81 0.025
spermatid development GO:0007286 4 0.025
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.024
maturation of ssu rrna GO:0030490 3 0.023
regulation of cysteine type endopeptidase activity GO:2000116 127 0.023
intracellular mrna localization GO:0008298 1 0.023
cellular amino acid metabolic process GO:0006520 116 0.023
regulation of peptidase activity GO:0052547 180 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
development of primary sexual characteristics GO:0045137 35 0.022
protein localization to organelle GO:0033365 280 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
developmental growth GO:0048589 48 0.021
anterior posterior axis specification GO:0009948 2 0.021
alternative mrna splicing via spliceosome GO:0000380 27 0.021
protein ubiquitination GO:0016567 314 0.020
gamete generation GO:0007276 25 0.020
histone modification GO:0016570 251 0.020
cellular ketone metabolic process GO:0042180 80 0.020
cell projection morphogenesis GO:0048858 129 0.019
response to abiotic stimulus GO:0009628 336 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
multicellular organism reproduction GO:0032504 42 0.019
purine nucleotide catabolic process GO:0006195 405 0.019
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
positive regulation of peptidase activity GO:0010952 88 0.018
positive regulation of growth GO:0045927 58 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.017
cell activation GO:0001775 213 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of cell cycle process GO:0010564 266 0.017
intracellular protein transport GO:0006886 270 0.016
locomotory behavior GO:0007626 1 0.016
microtubule cytoskeleton organization GO:0000226 176 0.016
gene silencing GO:0016458 49 0.016
rrna modification GO:0000154 2 0.016
aging GO:0007568 66 0.016
Worm
regulation of viral process GO:0050792 103 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
chromatin modification GO:0016568 298 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
cell morphogenesis GO:0000902 296 0.015
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.014
regulation of cell activation GO:0050865 125 0.014
positive regulation of proteolysis GO:0045862 142 0.014
negative regulation of multi organism process GO:0043901 92 0.014
nervous system development GO:0007399 293 0.014
cell cycle g1 s phase transition GO:0044843 80 0.014
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 3 0.014
guanosine containing compound catabolic process GO:1901069 239 0.013
biological adhesion GO:0022610 331 0.013
negative regulation of mrna catabolic process GO:1902373 4 0.013
maintenance of location GO:0051235 112 0.013
Worm
negative regulation of cell cycle GO:0045786 193 0.013
positive regulation of cell death GO:0010942 263 0.013
apoptotic signaling pathway GO:0097190 268 0.013
negative regulation of cell death GO:0060548 345 0.012
trabecula morphogenesis GO:0061383 2 0.012
zymogen activation GO:0031638 70 0.012
regulation of cell division GO:0051302 116 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
protein acylation GO:0043543 138 0.012
nuclear division GO:0000280 128 0.012
protein maturation GO:0051604 233 0.012
positive regulation of developmental growth GO:0048639 16 0.012
protein modification by small protein conjugation GO:0032446 342 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
cell projection organization GO:0030030 252 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
single fertilization GO:0007338 11 0.011
organelle assembly GO:0070925 176 0.011
interspecies interaction between organisms GO:0044419 156 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.011
dna repair GO:0006281 198 0.011
posttranscriptional gene silencing GO:0016441 25 0.010
nuclear migration GO:0007097 1 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
protein acetylation GO:0006473 116 0.010
positive regulation of transport GO:0051050 336 0.010
positive regulation of organelle organization GO:0010638 195 0.010

EIF3B disease predictions

Disease DO term ID Size Probability Func Analog Org
parkinson s disease DOID:14330 18 0.116
synucleinopathy DOID:0050890 22 0.116
central nervous system disease DOID:331 186 0.116
neurodegenerative disease DOID:1289 102 0.116
nervous system disease DOID:863 431 0.116
cancer DOID:162 167 0.043
disease of cellular proliferation DOID:14566 174 0.043
organ system cancer DOID:0050686 164 0.043