Homo sapiens

18 known processes

EIF3C

eukaryotic translation initiation factor 3, subunit C

(Aliases: EIF3CL,FLJ54404,FLJ55750,EIF3S8,FLJ54400,FLJ55450,FLJ78287,MGC189744,eIF3-p110,FLJ53378,MGC189737)

EIF3C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translation GO:0006412 132 0.285
neural crest cell development GO:0014032 3 0.236
cytoplasmic translational initiation GO:0002183 6 0.232
regulation of cellular ketone metabolic process GO:0010565 50 0.163
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.162
cellular amino acid metabolic process GO:0006520 116 0.147
multicellular organismal aging GO:0010259 3 0.126
determination of adult lifespan GO:0008340 2 0.111
cellular amine metabolic process GO:0044106 41 0.103
positive regulation of cellular amine metabolic process GO:0033240 7 0.097
rhythmic behavior GO:0007622 2 0.096
posttranscriptional regulation of gene expression GO:0010608 213 0.088
neuromuscular junction development GO:0007528 3 0.085
chromatin organization GO:0006325 351 0.084
cellular response to dna damage stimulus GO:0006974 379 0.084
epithelium development GO:0060429 227 0.080
amine metabolic process GO:0009308 44 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.079
associative learning GO:0008306 1 0.077
locomotory behavior GO:0007626 1 0.072
organophosphate catabolic process GO:0046434 430 0.069
regulation of cellular amine metabolic process GO:0033238 11 0.069
nucleoside catabolic process GO:0009164 408 0.068
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.066
nucleotide catabolic process GO:0009166 408 0.064
regulation of translation GO:0006417 89 0.063
mitotic cell cycle GO:0000278 326 0.061
purine ribonucleotide catabolic process GO:0009154 404 0.058
protein modification by small protein conjugation GO:0032446 342 0.058
purine nucleoside monophosphate metabolic process GO:0009126 186 0.056
interspecies interaction between organisms GO:0044419 156 0.056
purine ribonucleoside catabolic process GO:0046130 398 0.055
single organism cellular localization GO:1902580 332 0.055
ribonucleoside triphosphate catabolic process GO:0009203 391 0.052
translational initiation GO:0006413 48 0.052
regulation of endopeptidase activity GO:0052548 170 0.051
protein localization to organelle GO:0033365 280 0.050
glycosyl compound catabolic process GO:1901658 413 0.050
purine nucleotide catabolic process GO:0006195 405 0.048
ribonucleotide catabolic process GO:0009261 405 0.047
regulation of establishment of protein localization GO:0070201 242 0.047
histone acetylation GO:0016573 93 0.046
rna interference GO:0016246 4 0.046
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.045
regulation of proteolysis GO:0030162 293 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.044
regulation of mitotic cell cycle GO:0007346 189 0.044
negative regulation of cell cycle GO:0045786 193 0.044
regulation of cysteine type endopeptidase activity GO:2000116 127 0.043
nucleoside triphosphate catabolic process GO:0009143 394 0.043
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.042
regulation of cell cycle GO:0051726 393 0.042
regulation of translational initiation GO:0006446 24 0.042
circulatory system development GO:0072359 262 0.041
cellular ketone metabolic process GO:0042180 80 0.040
response to biotic stimulus GO:0009607 276 0.040
protein maturation GO:0051604 233 0.039
tube development GO:0035295 125 0.039
regeneration GO:0031099 4 0.039
mitotic cell cycle phase transition GO:0044772 162 0.039
embryonic epithelial tube formation GO:0001838 4 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
protein acetylation GO:0006473 116 0.038
protein ubiquitination GO:0016567 314 0.038
cytoplasmic transport GO:0016482 379 0.038
regulation of peptidase activity GO:0052547 180 0.037
cellular response to growth factor stimulus GO:0071363 197 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
purine nucleoside catabolic process GO:0006152 398 0.037
ribonucleoside monophosphate metabolic process GO:0009161 187 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.036
maintenance of location GO:0051235 112 0.036
post embryonic development GO:0009791 2 0.036
positive regulation of organelle organization GO:0010638 195 0.036
intracellular protein transport GO:0006886 270 0.036
regulation of protein localization GO:0032880 296 0.036
regulation of protein targeting GO:1903533 91 0.036
rho protein signal transduction GO:0007266 26 0.036
hindbrain development GO:0030902 3 0.036
purine containing compound catabolic process GO:0072523 411 0.035
ribonucleoside catabolic process GO:0042454 406 0.035
negative regulation of peptidase activity GO:0010466 91 0.035
negative regulation of proteolysis GO:0045861 132 0.035
cation transport GO:0006812 331 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
carbohydrate metabolic process GO:0005975 207 0.034
photoreceptor cell differentiation GO:0046530 2 0.033
multi organism cellular process GO:0044764 156 0.033
protein acylation GO:0043543 138 0.033
cardiovascular system development GO:0072358 262 0.033
cellular response to hormone stimulus GO:0032870 125 0.033
negative regulation of protein metabolic process GO:0051248 391 0.032
mesenchymal cell development GO:0014031 50 0.032
mitotic cell cycle process GO:1903047 286 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
protein targeting GO:0006605 187 0.031
tor signaling GO:0031929 39 0.031
positive regulation of cellular component organization GO:0051130 376 0.031
regulation of protein processing GO:0070613 150 0.031
single organism nuclear import GO:1902593 104 0.031
regulation of growth GO:0040008 165 0.031
meiotic chromosome segregation GO:0045132 4 0.031
activation of innate immune response GO:0002218 55 0.031
response to growth factor GO:0070848 205 0.031
cell fate determination GO:0001709 3 0.031
system process GO:0003008 349 0.030
peptidyl lysine modification GO:0018205 144 0.030
nucleoside monophosphate catabolic process GO:0009125 159 0.030
internal protein amino acid acetylation GO:0006475 101 0.030
mesenchymal cell differentiation GO:0048762 52 0.029
purine nucleoside monophosphate catabolic process GO:0009128 158 0.029
response to external biotic stimulus GO:0043207 261 0.029
innate immune response GO:0045087 178 0.029
female gamete generation GO:0007292 2 0.029
negative regulation of protein processing GO:0010955 142 0.028
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.028
small gtpase mediated signal transduction GO:0007264 78 0.028
covalent chromatin modification GO:0016569 254 0.027
mesenchyme development GO:0060485 59 0.027
cellular response to cytokine stimulus GO:0071345 181 0.026
viral process GO:0016032 146 0.026
segmentation GO:0035282 4 0.026
nuclear transport GO:0051169 179 0.026
cellular response to nitrogen compound GO:1901699 144 0.026
regulation of protein maturation GO:1903317 150 0.026
peptidyl lysine acetylation GO:0018394 101 0.026
response to nitrogen compound GO:1901698 184 0.026
regulation of intracellular protein transport GO:0033157 123 0.026
defense response GO:0006952 315 0.026
response to abiotic stimulus GO:0009628 336 0.025
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
internal peptidyl lysine acetylation GO:0018393 97 0.025
response to hypoxia GO:0001666 96 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
oocyte development GO:0048599 1 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
skin development GO:0043588 76 0.024
membrane organization GO:0061024 292 0.024
cell cycle phase transition GO:0044770 173 0.024
cell growth GO:0016049 160 0.024
protein import GO:0017038 130 0.024
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.024
protein targeting to nucleus GO:0044744 104 0.024
cellular response to peptide hormone stimulus GO:0071375 56 0.024
guanosine containing compound catabolic process GO:1901069 239 0.024
negative regulation of developmental process GO:0051093 247 0.024
positive regulation of apoptotic process GO:0043065 246 0.024
lipid metabolic process GO:0006629 381 0.024
negative regulation of endopeptidase activity GO:0010951 84 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
stem cell differentiation GO:0048863 93 0.023
chromatin modification GO:0016568 298 0.023
response to bacterium GO:0009617 144 0.023
histone serine phosphorylation GO:0035404 4 0.023
positive regulation of transport GO:0051050 336 0.023
protein catabolic process GO:0030163 325 0.023
histone modification GO:0016570 251 0.023
oogenesis GO:0048477 2 0.023
nuclear import GO:0051170 106 0.022
immune response GO:0006955 307 0.022
tube closure GO:0060606 3 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.022
protein processing GO:0016485 226 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
regulation of protein import into nucleus GO:0042306 78 0.021
regulation of protein localization to nucleus GO:1900180 85 0.021
positive regulation of translational initiation GO:0045948 7 0.021
spermatid differentiation GO:0048515 4 0.021
positive regulation of catabolic process GO:0009896 310 0.021
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
ras protein signal transduction GO:0007265 73 0.021
vesicle mediated transport GO:0016192 371 0.021
response to peptide hormone GO:0043434 61 0.021
regulation of chromosome organization GO:0033044 103 0.021
anterior posterior axis specification GO:0009948 2 0.021
regulation of viral process GO:0050792 103 0.021
primary neural tube formation GO:0014020 3 0.021
protein import into nucleus GO:0006606 104 0.021
wnt signaling pathway GO:0016055 156 0.020
cell morphogenesis GO:0000902 296 0.020
chromosome segregation GO:0007059 114 0.020
regulation of histone acetylation GO:0035065 19 0.020
negative regulation of hydrolase activity GO:0051346 182 0.020
viral life cycle GO:0019058 132 0.020
neurological system process GO:0050877 163 0.020
positive regulation of intracellular transport GO:0032388 104 0.020
spermatid development GO:0007286 4 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
response to oxygen containing compound GO:1901700 369 0.020
response to other organism GO:0051707 261 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
g1 s transition of mitotic cell cycle GO:0000082 78 0.019
regulation of protein transport GO:0051223 213 0.019
negative regulation of intracellular transport GO:0032387 60 0.019
regulation of developmental pigmentation GO:0048070 2 0.019
cellular response to organonitrogen compound GO:0071417 124 0.019
protein modification by small protein removal GO:0070646 92 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of mitotic cell cycle phase transition GO:1901990 118 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.018
inner ear morphogenesis GO:0042472 4 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
organ morphogenesis GO:0009887 147 0.018
positive regulation of defense response GO:0031349 87 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
metal ion transport GO:0030001 272 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
response to organic cyclic compound GO:0014070 204 0.018
mitotic spindle elongation GO:0000022 4 0.018
neural tube closure GO:0001843 3 0.018
spindle elongation GO:0051231 4 0.018
growth GO:0040007 202 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
cellular response to peptide GO:1901653 59 0.017
cell cycle g1 s phase transition GO:0044843 80 0.017
positive regulation of chromatin modification GO:1903310 30 0.017
oocyte differentiation GO:0009994 2 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
motor neuron axon guidance GO:0008045 2 0.017
negative regulation of protein transport GO:0051224 75 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
response to lipid GO:0033993 206 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.017
regulation of protein catabolic process GO:0042176 155 0.017
positive regulation of immune system process GO:0002684 283 0.017
microtubule based process GO:0007017 210 0.017
cell part morphogenesis GO:0032990 137 0.017
positive regulation of cell death GO:0010942 263 0.017
regulation of transferase activity GO:0051338 355 0.017
cellular response to extracellular stimulus GO:0031668 72 0.017
regulation of cellular component movement GO:0051270 334 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
extrinsic apoptotic signaling pathway GO:0097191 119 0.017
response to organonitrogen compound GO:0010243 156 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.016
response to molecule of bacterial origin GO:0002237 82 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
regulation of innate immune response GO:0045088 97 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
negative regulation of cell growth GO:0030308 83 0.016
signal transduction by p53 class mediator GO:0072331 72 0.016
positive regulation of chromosome organization GO:2001252 41 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
heart development GO:0007507 95 0.016
endomembrane system organization GO:0010256 196 0.016
neuron differentiation GO:0030182 138 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
peptidyl serine modification GO:0018209 106 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.015
cellular carbohydrate metabolic process GO:0044262 84 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
histone h3 s10 phosphorylation GO:0043987 3 0.015
negative regulation of multi organism process GO:0043901 92 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
cilium organization GO:0044782 68 0.015
response to decreased oxygen levels GO:0036293 96 0.015
cell projection morphogenesis GO:0048858 129 0.015
regulation of cell cycle phase transition GO:1901987 126 0.015
activation of immune response GO:0002253 114 0.015
actin mediated cell contraction GO:0070252 12 0.015
response to oxygen levels GO:0070482 100 0.015
regulation of protein stability GO:0031647 87 0.015
negative regulation of cytoplasmic transport GO:1903650 46 0.015
positive regulation of cell cycle GO:0045787 140 0.014
innate immune response activating signal transduction GO:0002758 48 0.014
regulation of cell differentiation GO:0045595 393 0.014
positive regulation of mitotic cell cycle GO:0045931 60 0.014
cell development GO:0048468 328 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
gtp metabolic process GO:0046039 239 0.014
response to hormone GO:0009725 175 0.014
negative regulation of cell death GO:0060548 345 0.014
aging GO:0007568 66 0.014
cellular lipid metabolic process GO:0044255 303 0.014
positive regulation of innate immune response GO:0045089 79 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
compound eye development GO:0048749 1 0.014
viral gene expression GO:0019080 35 0.014
histone h2a s1 phosphorylation GO:0043990 1 0.014
rna processing GO:0006396 255 0.014
glycoprotein metabolic process GO:0009100 110 0.014
cytokine production GO:0001816 247 0.014
positive regulation of developmental process GO:0051094 314 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
regulation of chromatin organization GO:1902275 56 0.014
regulation of nervous system development GO:0051960 88 0.014
sequestering of metal ion GO:0051238 24 0.014
nervous system development GO:0007399 293 0.014
response to insulin GO:0032868 45 0.013
negative regulation of catabolic process GO:0009895 104 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
regulation of chromatin modification GO:1903308 51 0.013
response to axon injury GO:0048678 1 0.013
positive regulation of histone modification GO:0031058 29 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
cell projection organization GO:0030030 252 0.013
response to cytokine GO:0034097 232 0.013
negative regulation of viral process GO:0048525 66 0.013
apoptotic signaling pathway GO:0097190 268 0.013
chemical homeostasis GO:0048878 306 0.013
oocyte maturation GO:0001556 1 0.013
organ formation GO:0048645 3 0.013
transmembrane transport GO:0055085 399 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
lipid localization GO:0010876 106 0.012
negative regulation of transport GO:0051051 176 0.012
cellular response to nutrient levels GO:0031669 69 0.012
cell cell signaling GO:0007267 155 0.012
pattern recognition receptor signaling pathway GO:0002221 48 0.012
regulation of defense response GO:0031347 154 0.012
hindlimb morphogenesis GO:0035137 2 0.012
blastoderm segmentation GO:0007350 2 0.012
atp metabolic process GO:0046034 176 0.012
single organism membrane organization GO:0044802 268 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
dephosphorylation GO:0016311 209 0.012
regulation of protein acetylation GO:1901983 25 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
atp catabolic process GO:0006200 157 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
protein localization to nucleus GO:0034504 136 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
cation transmembrane transport GO:0098655 238 0.012
cellular response to interleukin 1 GO:0071347 35 0.012
positive regulation of epithelial cell proliferation GO:0050679 65 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
cytokine mediated signaling pathway GO:0019221 109 0.012
response to nutrient levels GO:0031667 81 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
gene silencing by mirna GO:0035195 23 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
plasma membrane organization GO:0007009 115 0.012
protein localization to membrane GO:0072657 160 0.012
regulation of cell activation GO:0050865 125 0.012
regulation of cell cycle process GO:0010564 266 0.012
positive regulation of peptidase activity GO:0010952 88 0.012
oxidation reduction process GO:0055114 396 0.012
posttranscriptional gene silencing by rna GO:0035194 25 0.012
regulation of cell growth GO:0001558 135 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
peptidyl serine phosphorylation GO:0018105 101 0.011
endosomal transport GO:0016197 129 0.011
sex determination GO:0007530 3 0.011
epithelial cell differentiation GO:0030855 141 0.011
regulation of secretion GO:0051046 194 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
embryonic organ development GO:0048568 36 0.011
gtp catabolic process GO:0006184 237 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
negative regulation of protein maturation GO:1903318 142 0.011
neuron development GO:0048666 113 0.011
cellular response to external stimulus GO:0071496 111 0.011
adult locomotory behavior GO:0008344 1 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
protein oligomerization GO:0051259 173 0.011
response to interleukin 1 GO:0070555 47 0.011
modification of morphology or physiology of other organism GO:0035821 43 0.011
developmental programmed cell death GO:0010623 3 0.011
behavior GO:0007610 112 0.011
regulation of epithelial cell proliferation GO:0050678 113 0.011
somitogenesis GO:0001756 2 0.011
myoblast fusion GO:0007520 1 0.011
angiogenesis GO:0001525 147 0.011
specification of organ identity GO:0010092 3 0.011
lipid modification GO:0030258 84 0.011
positive regulation of cell growth GO:0030307 48 0.011
response to peptide GO:1901652 65 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
regulation of protein complex assembly GO:0043254 147 0.011
mitochondrion organization GO:0007005 156 0.011
toll like receptor signaling pathway GO:0002224 25 0.011
regulation of intracellular transport GO:0032386 195 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
lipid biosynthetic process GO:0008610 177 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
convergent extension GO:0060026 1 0.010
divalent inorganic cation transport GO:0072511 158 0.010
negative regulation of protein localization to nucleus GO:1900181 34 0.010
regulation of multi organism process GO:0043900 157 0.010
salivary gland morphogenesis GO:0007435 4 0.010
positive regulation of immune response GO:0050778 159 0.010
sensory perception of pain GO:0019233 4 0.010
negative regulation of intracellular protein transport GO:0090317 42 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
peptide metabolic process GO:0006518 51 0.010
small molecule biosynthetic process GO:0044283 157 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
positive regulation of protein transport GO:0051222 135 0.010
tissue regeneration GO:0042246 3 0.010
protein homooligomerization GO:0051260 100 0.010
dna conformation change GO:0071103 113 0.010
cell projection assembly GO:0030031 126 0.010
regulation of cell development GO:0060284 161 0.010
neurogenesis GO:0022008 169 0.010
digestive tract development GO:0048565 75 0.010
generation of neurons GO:0048699 152 0.010
actin filament based movement GO:0030048 17 0.010

EIF3C disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.033
developmental disorder of mental health DOID:0060037 29 0.033
central nervous system disease DOID:331 186 0.030
neurodegenerative disease DOID:1289 102 0.030
nervous system disease DOID:863 431 0.030
sensory system disease DOID:0050155 203 0.027
eye and adnexa disease DOID:1492 150 0.027
eye disease DOID:5614 149 0.027
musculoskeletal system disease DOID:17 223 0.023
retinal disease DOID:5679 118 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
organ system cancer DOID:0050686 164 0.018
specific developmental disorder DOID:0060038 19 0.017
intellectual disability DOID:1059 13 0.017
connective tissue disease DOID:65 109 0.014
retinal degeneration DOID:8466 89 0.012
bone disease DOID:0080001 88 0.012
disease of metabolism DOID:0014667 295 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011
inherited metabolic disorder DOID:655 242 0.011