Homo sapiens

18 known processes

EIF3D

eukaryotic translation initiation factor 3, subunit D

(Aliases: MGC126526,MGC17258,EIF3S7,eIF3-p66,eIF3-zeta)

EIF3D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytoplasmic translational initiation GO:0002183 6 1.000
translational initiation GO:0006413 48 1.000
translation GO:0006412 132 0.950
female gamete generation GO:0007292 2 0.850
Worm
maturation of ssu rrna GO:0030490 3 0.825
ribosomal small subunit biogenesis GO:0042274 13 0.765
post embryonic development GO:0009791 2 0.570
positive regulation of programmed cell death GO:0043068 249 0.513
vesicle mediated transport GO:0016192 371 0.452
Worm
multicellular organismal aging GO:0010259 3 0.451
neuron development GO:0048666 113 0.251
regulation of proteolysis GO:0030162 293 0.245
cellular macromolecular complex assembly GO:0034622 324 0.231
receptor mediated endocytosis GO:0006898 84 0.218
Worm
ribonucleoprotein complex subunit organization GO:0071826 81 0.197
rna processing GO:0006396 255 0.191
rrna metabolic process GO:0016072 40 0.176
positive regulation of apoptotic process GO:0043065 246 0.173
aging GO:0007568 66 0.151
mitotic cell cycle GO:0000278 326 0.150
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.148
transmembrane transport GO:0055085 399 0.145
atp transport GO:0015867 4 0.140
cell development GO:0048468 328 0.138
Worm
formation of translation preinitiation complex GO:0001731 4 0.138
endocytosis GO:0006897 159 0.137
Worm
ncrna processing GO:0034470 83 0.136
regulation of translational initiation GO:0006446 24 0.135
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.132
tube development GO:0035295 125 0.132
purine nucleoside monophosphate metabolic process GO:0009126 186 0.130
oogenesis GO:0048477 2 0.128
Worm
purine ribonucleotide catabolic process GO:0009154 404 0.123
positive regulation of gtp catabolic process GO:0033126 166 0.122
system process GO:0003008 349 0.113
neuron projection development GO:0031175 106 0.113
regulation of cellular component biogenesis GO:0044087 281 0.112
mrna splicing via spliceosome GO:0000398 89 0.111
protein processing GO:0016485 226 0.107
glycosyl compound catabolic process GO:1901658 413 0.104
cellular macromolecule catabolic process GO:0044265 380 0.103
cell projection organization GO:0030030 252 0.101
purine nucleoside triphosphate metabolic process GO:0009144 412 0.100
positive regulation of hydrolase activity GO:0051345 331 0.100
negative regulation of protein metabolic process GO:0051248 391 0.099
ncrna metabolic process GO:0034660 108 0.095
protein modification by small protein conjugation GO:0032446 342 0.094
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.093
nucleotide catabolic process GO:0009166 408 0.085
purine containing compound catabolic process GO:0072523 411 0.080
posttranscriptional regulation of gene expression GO:0010608 213 0.078
rrna export from nucleus GO:0006407 1 0.078
response to oxygen containing compound GO:1901700 369 0.076
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.073
regulation of nucleoside metabolic process GO:0009118 209 0.073
regulation of cell cycle process GO:0010564 266 0.072
nucleoside triphosphate metabolic process GO:0009141 422 0.067
rrna processing GO:0006364 35 0.065
ribose phosphate biosynthetic process GO:0046390 82 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.064
nuclear transcribed mrna catabolic process GO:0000956 48 0.063
circulatory system development GO:0072359 262 0.060
positive regulation of cell death GO:0010942 263 0.060
ribonucleoside monophosphate metabolic process GO:0009161 187 0.060
generation of neurons GO:0048699 152 0.059
neuron differentiation GO:0030182 138 0.059
negative regulation of apoptotic process GO:0043066 316 0.059
maintenance of location GO:0051235 112 0.059
sex differentiation GO:0007548 45 0.057
Worm
purine nucleoside triphosphate catabolic process GO:0009146 392 0.057
purine nucleoside catabolic process GO:0006152 398 0.057
histone h2b conserved c terminal lysine deubiquitination GO:0035616 1 0.056
nervous system development GO:0007399 293 0.054
positive regulation of gastrulation GO:2000543 2 0.051
protein maturation GO:0051604 233 0.050
response to cytokine GO:0034097 232 0.050
purine ribonucleoside catabolic process GO:0046130 398 0.048
oocyte differentiation GO:0009994 2 0.048
negative regulation of catabolic process GO:0009895 104 0.048
ribonucleoside catabolic process GO:0042454 406 0.047
mesenchyme development GO:0060485 59 0.047
regulation of translational elongation GO:0006448 2 0.047
organophosphate catabolic process GO:0046434 430 0.047
gtp metabolic process GO:0046039 239 0.047
purine ribonucleoside metabolic process GO:0046128 437 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
cell morphogenesis GO:0000902 296 0.043
guanosine containing compound catabolic process GO:1901069 239 0.042
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.042
regulation of nucleotide catabolic process GO:0030811 205 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
immune system development GO:0002520 195 0.041
rrna modification GO:0000154 2 0.041
endomembrane system organization GO:0010256 196 0.041
positive regulation of cellular component organization GO:0051130 376 0.038
regulation of purine nucleotide metabolic process GO:1900542 264 0.038
cellular amine metabolic process GO:0044106 41 0.038
ribonucleoprotein complex assembly GO:0022618 78 0.038
gmp metabolic process GO:0046037 4 0.038
cellular response to dna damage stimulus GO:0006974 379 0.036
negative regulation of cellular component organization GO:0051129 235 0.036
developmental process involved in reproduction GO:0003006 66 0.036
Worm
regulation of mrna catabolic process GO:0061013 13 0.035
determination of adult lifespan GO:0008340 2 0.035
ribosome biogenesis GO:0042254 48 0.035
rna catabolic process GO:0006401 71 0.035
secretion by cell GO:0032940 226 0.035
nucleoside catabolic process GO:0009164 408 0.035
porphyrin containing compound metabolic process GO:0006778 10 0.034
centrosome organization GO:0051297 58 0.034
guanosine containing compound metabolic process GO:1901068 244 0.034
regulation of gtp catabolic process GO:0033124 180 0.034
spermatid differentiation GO:0048515 4 0.033
protein modification by small protein removal GO:0070646 92 0.032
cellular response to cytokine stimulus GO:0071345 181 0.031
mrna metabolic process GO:0016071 175 0.030
regulation of protein complex assembly GO:0043254 147 0.030
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.030
amine metabolic process GO:0009308 44 0.029
demethylation GO:0070988 37 0.029
apoptotic signaling pathway GO:0097190 268 0.029
nucleotide biosynthetic process GO:0009165 109 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
ribonucleoprotein complex biogenesis GO:0022613 116 0.027
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.026
muscle cell cellular homeostasis GO:0046716 3 0.026
lipid localization GO:0010876 106 0.026
camp catabolic process GO:0006198 8 0.026
protein secretion GO:0009306 98 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
regulation of mitosis GO:0007088 63 0.026
regulation of nucleotide metabolic process GO:0006140 269 0.026
regulation of translation GO:0006417 89 0.026
single organism membrane organization GO:0044802 268 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
negative regulation of cell death GO:0060548 345 0.025
rna modification GO:0009451 27 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
epithelium development GO:0060429 227 0.024
cardiovascular system development GO:0072358 262 0.024
regeneration GO:0031099 4 0.024
protein oligomerization GO:0051259 173 0.024
cell projection morphogenesis GO:0048858 129 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
nitrogen compound transport GO:0071705 191 0.023
golgi organization GO:0007030 38 0.023
negative regulation of cellular catabolic process GO:0031330 83 0.023
neuronal action potential GO:0019228 9 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
secretion GO:0046903 254 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
cellular homeostasis GO:0019725 196 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
negative regulation of programmed cell death GO:0043069 321 0.020
negative regulation of developmental process GO:0051093 247 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
oocyte development GO:0048599 1 0.020
cellular ketone metabolic process GO:0042180 80 0.020
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
protein deubiquitination GO:0016579 79 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
chromatin organization GO:0006325 351 0.019
regulation of generation of precursor metabolites and energy GO:0043467 27 0.019
stem cell development GO:0048864 69 0.018
autophagic cell death GO:0048102 3 0.018
reproduction GO:0000003 63 0.018
Worm
neurogenesis GO:0022008 169 0.018
lipid storage GO:0019915 28 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.017
regulation of protein stability GO:0031647 87 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.017
protein localization to membrane GO:0072657 160 0.017
positive regulation of proteolysis GO:0045862 142 0.017
gtp catabolic process GO:0006184 237 0.017
reproductive process GO:0022414 106 0.017
Worm
oxidation reduction process GO:0055114 396 0.017
negative regulation of organelle organization GO:0010639 126 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
regulation of cellular response to stress GO:0080135 244 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
development of primary sexual characteristics GO:0045137 35 0.016
Worm
notch signaling pathway GO:0007219 31 0.016
regulation of cellular component movement GO:0051270 334 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
cell type specific apoptotic process GO:0097285 125 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.016
organelle assembly GO:0070925 176 0.016
locomotory behavior GO:0007626 1 0.016
leukocyte activation GO:0045321 164 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
multi organism cellular process GO:0044764 156 0.015
positive regulation of developmental process GO:0051094 314 0.014
positive regulation of dna repair GO:0045739 25 0.014
behavior GO:0007610 112 0.014
centrosome cycle GO:0007098 32 0.014
embryo development GO:0009790 123 0.014
Worm
organelle fission GO:0048285 149 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
negative regulation of protein modification process GO:0031400 200 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
regulation of chromosome organization GO:0033044 103 0.014
protein tetramerization GO:0051262 47 0.014
reproductive system development GO:0061458 56 0.014
Worm
viral life cycle GO:0019058 132 0.014
trabecula morphogenesis GO:0061383 2 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
purine nucleotide transport GO:0015865 6 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
positive regulation of mitochondrial depolarization GO:0051901 3 0.013
protein localization to organelle GO:0033365 280 0.013
negative regulation of kinase activity GO:0033673 106 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.013
cell part morphogenesis GO:0032990 137 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
g1 s transition of mitotic cell cycle GO:0000082 78 0.013
protein ubiquitination GO:0016567 314 0.013
axon development GO:0061564 34 0.013
regulation of camp metabolic process GO:0030814 52 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
zymogen activation GO:0031638 70 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
ncrna 3 end processing GO:0043628 4 0.012
rna splicing GO:0008380 131 0.012
cellular ion homeostasis GO:0006873 168 0.012
cytoplasmic transport GO:0016482 379 0.012
response to inorganic substance GO:0010035 127 0.012
sexual reproduction GO:0019953 37 0.012
Worm
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.012
microtubule based process GO:0007017 210 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
regulation of cell migration GO:0030334 289 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
Worm
mitotic cell cycle process GO:1903047 286 0.012
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 3 0.012
nucleobase containing compound transport GO:0015931 51 0.012
organ morphogenesis GO:0009887 147 0.012
single organism cellular localization GO:1902580 332 0.012
negative regulation of catalytic activity GO:0043086 335 0.012
positive regulation of organelle organization GO:0010638 195 0.012
dna demethylation GO:0080111 12 0.012
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.011
cuticle development GO:0042335 1 0.011
mrna processing GO:0006397 133 0.011
carbohydrate homeostasis GO:0033500 31 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
positive regulation of defense response GO:0031349 87 0.011
negative regulation of transport GO:0051051 176 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cellular lipid metabolic process GO:0044255 303 0.011
regulation of cell cycle GO:0051726 393 0.011
cell activation GO:0001775 213 0.011
immune response GO:0006955 307 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
mitotic nuclear division GO:0007067 119 0.011
regulation of cyclic nucleotide phosphodiesterase activity GO:0051342 4 0.011
negative regulation of cell cycle phase transition GO:1901988 89 0.011
neuron projection morphogenesis GO:0048812 50 0.010
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901029 4 0.010
metal ion transport GO:0030001 272 0.010
regulation of cellular amine metabolic process GO:0033238 11 0.010
response to hormone GO:0009725 175 0.010
generation of precursor metabolites and energy GO:0006091 68 0.010
cellular amino acid metabolic process GO:0006520 116 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
posttranscriptional gene silencing by rna GO:0035194 25 0.010
cyclic nucleotide catabolic process GO:0009214 9 0.010
negative regulation of protein catabolic process GO:0042177 59 0.010

EIF3D disease predictions

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 118 0.020
sensory system disease DOID:0050155 203 0.020
eye and adnexa disease DOID:1492 150 0.020
nervous system disease DOID:863 431 0.020
eye disease DOID:5614 149 0.020
immune system disease DOID:2914 155 0.012