Homo sapiens

224 known processes

FADD

Fas (TNFRSF6)-associated via death domain

(Aliases: MORT1,MGC8528)

FADD biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to increased oxygen levels GO:0036295 4 1.000
trail activated apoptotic signaling pathway GO:0036462 4 1.000
programmed necrotic cell death GO:0097300 18 1.000
response to cobalt ion GO:0032025 1 0.999
skeletal muscle satellite cell proliferation GO:0014841 1 0.997
cellular response to hyperoxia GO:0071455 4 0.997
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.994
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.992
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.989
apoptotic signaling pathway GO:0097190 268 0.987
cellular response to mechanical stimulus GO:0071260 39 0.983
extrinsic apoptotic signaling pathway GO:0097191 119 0.983
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.983
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.980
positive regulation of apoptotic signaling pathway GO:2001235 70 0.978
positive regulation of apoptotic process GO:0043065 246 0.962
positive regulation of cellular amine metabolic process GO:0033240 7 0.961
cell type specific apoptotic process GO:0097285 125 0.948
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.945
i kappab kinase nf kappab signaling GO:0007249 166 0.944
positive regulation of programmed cell death GO:0043068 249 0.939
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.937
positive regulation of jak stat cascade GO:0046427 35 0.935
t cell apoptotic process GO:0070231 12 0.935
Mouse
positive regulation of cell death GO:0010942 263 0.934
regulation of apoptotic signaling pathway GO:2001233 175 0.930
response to increased oxygen levels GO:0036296 4 0.929
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.922
lymphocyte apoptotic process GO:0070227 20 0.917
Mouse
positive regulation of peptidase activity GO:0010952 88 0.913
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.913
cellular amine metabolic process GO:0044106 41 0.907
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.906
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.905
regulation of cellular amino acid metabolic process GO:0006521 6 0.904
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.902
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.896
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.891
response to hyperoxia GO:0055093 4 0.887
cell fate determination GO:0001709 3 0.879
jak stat cascade GO:0007259 46 0.865
intrinsic apoptotic signaling pathway GO:0097193 127 0.849
regulation of cellular ketone metabolic process GO:0010565 50 0.845
amine metabolic process GO:0009308 44 0.844
necroptotic process GO:0070266 16 0.842
regulation of endopeptidase activity GO:0052548 170 0.837
apoptotic mitochondrial changes GO:0008637 57 0.835
regulation of proteolysis GO:0030162 293 0.826
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.806
protein processing GO:0016485 226 0.797
positive regulation of phosphorylation GO:0042327 394 0.758
cellular ketone metabolic process GO:0042180 80 0.741
positive regulation of nf kappab import into nucleus GO:0042346 13 0.740
necrotic cell death GO:0070265 21 0.732
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.726
protein maturation GO:0051604 233 0.693
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.686
cellular amino acid metabolic process GO:0006520 116 0.673
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.639
response to mechanical stimulus GO:0009612 51 0.632
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.631
regulation of peptidase activity GO:0052547 180 0.618
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.615
regulation of protein processing GO:0070613 150 0.614
regulation of myeloid cell differentiation GO:0045637 81 0.611
positive regulation of myeloid cell differentiation GO:0045639 39 0.607
negative regulation of apoptotic process GO:0043066 316 0.598
Mouse
negative regulation of cell death GO:0060548 345 0.581
Mouse
positive regulation of nik nf kappab signaling GO:1901224 10 0.569
negative regulation of endopeptidase activity GO:0010951 84 0.562
regulation of cysteine type endopeptidase activity GO:2000116 127 0.560
cellular response to abiotic stimulus GO:0071214 117 0.556
release of cytochrome c from mitochondria GO:0001836 35 0.555
maintenance of protein location in cell GO:0032507 56 0.554
regulation of cellular amine metabolic process GO:0033238 11 0.550
response to water GO:0009415 2 0.549
positive regulation of protein kinase activity GO:0045860 190 0.533
neuron projection regeneration GO:0031102 1 0.527
cellular response to oxygen levels GO:0071453 55 0.526
inflammatory response GO:0006954 79 0.522
zymogen activation GO:0031638 70 0.520
positive regulation of protein phosphorylation GO:0001934 313 0.513
cellular response to external stimulus GO:0071496 111 0.513
negative regulation of mitotic cell cycle GO:0045930 102 0.484
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.483
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.469
regulation of cell cycle GO:0051726 393 0.464
cellular response to tumor necrosis factor GO:0071356 63 0.449
negative regulation of defense response GO:0031348 47 0.434
regulation of cell cycle phase transition GO:1901987 126 0.423
negative regulation of inflammatory response GO:0050728 22 0.409
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.401
response to cycloheximide GO:0046898 1 0.401
positive regulation of proteolysis GO:0045862 142 0.394
regulation of necroptotic process GO:0060544 7 0.394
Mouse
regulation of transcription factor import into nucleus GO:0042990 39 0.388
mitotic dna damage checkpoint GO:0044773 28 0.383
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 4 0.378
positive regulation of macrophage differentiation GO:0045651 7 0.377
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.373
Mouse
regulation of inflammatory response GO:0050727 46 0.372
tyrosine phosphorylation of stat protein GO:0007260 33 0.369
chemotaxis GO:0006935 157 0.363
intracellular protein transport GO:0006886 270 0.359
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.354
negative regulation of protein deubiquitination GO:0090086 3 0.352
response to estradiol GO:0032355 23 0.345
cellular protein catabolic process GO:0044257 261 0.339
negative regulation of peptidase activity GO:0010466 91 0.336
regulation of response to external stimulus GO:0032101 222 0.331
response to abiotic stimulus GO:0009628 336 0.331
cell cycle phase transition GO:0044770 173 0.325
positive regulation of endopeptidase activity GO:0010950 84 0.318
necroptotic signaling pathway GO:0097527 6 0.316
regulation of intracellular transport GO:0032386 195 0.308
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 8 0.298
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.297
positive regulation of developmental process GO:0051094 314 0.295
positive regulation of bone resorption GO:0045780 2 0.288
protein homooligomerization GO:0051260 100 0.287
mitotic cell cycle process GO:1903047 286 0.282
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.276
regulation of cellular response to stress GO:0080135 244 0.273
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.270
inflammatory cell apoptotic process GO:0006925 3 0.266
negative regulation of apoptotic signaling pathway GO:2001234 97 0.265
mitotic cell cycle checkpoint GO:0007093 68 0.264
negative regulation of proteolysis GO:0045861 132 0.262
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.257
negative regulation of protein processing GO:0010955 142 0.246
dna damage checkpoint GO:0000077 68 0.243
response to virus GO:0009615 126 0.240
dna integrity checkpoint GO:0031570 71 0.240
regulation of cell cycle process GO:0010564 266 0.238
positive regulation of hydrolase activity GO:0051345 331 0.237
execution phase of apoptosis GO:0097194 32 0.234
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.229
response to radiation GO:0009314 151 0.229
cellular response to dna damage stimulus GO:0006974 379 0.229
response to external biotic stimulus GO:0043207 261 0.228
vasculature development GO:0001944 181 0.228
cellular macromolecule catabolic process GO:0044265 380 0.217
regulation of nucleocytoplasmic transport GO:0046822 98 0.214
regulation of myoblast fusion GO:1901739 1 0.213
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.212
regulation of leukocyte differentiation GO:1902105 61 0.211
response to oxygen containing compound GO:1901700 369 0.209
immune system development GO:0002520 195 0.206
toll like receptor 2 signaling pathway GO:0034134 4 0.200
peptidyl tyrosine phosphorylation GO:0018108 170 0.197
negative regulation of protein import into nucleus GO:0042308 30 0.196
signal transduction by phosphorylation GO:0023014 297 0.190
negative regulation of intracellular signal transduction GO:1902532 183 0.189
negative regulation of response to wounding GO:1903035 47 0.180
regulation of protein targeting GO:1903533 91 0.180
regulation of mitotic cell cycle GO:0007346 189 0.179
transmembrane transport GO:0055085 399 0.175
regulation of cell cycle g1 s phase transition GO:1902806 42 0.173
mitotic cell cycle phase transition GO:0044772 162 0.170
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.169
response to endoplasmic reticulum stress GO:0034976 49 0.167
neural nucleus development GO:0048857 47 0.164
cellular response to estrogen stimulus GO:0071391 16 0.163
positive regulation of mapk cascade GO:0043410 190 0.163
engulfment of apoptotic cell GO:0043652 2 0.161
regulation of mitotic cell cycle phase transition GO:1901990 118 0.157
nitrogen compound transport GO:0071705 191 0.146
regulation of myeloid leukocyte differentiation GO:0002761 39 0.145
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.145
activation induced cell death of t cells GO:0006924 2 0.142
Mouse
negative regulation of cell cycle phase transition GO:1901988 89 0.138
single organism cellular localization GO:1902580 332 0.136
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.135
thymocyte apoptotic process GO:0070242 2 0.135
response to cytokine GO:0034097 232 0.132
regulation of defense response GO:0031347 154 0.126
regulation of lymphocyte apoptotic process GO:0070228 15 0.126
Mouse
protein oligomerization GO:0051259 173 0.126
positive regulation of protein homooligomerization GO:0032464 7 0.125
regulation of endothelial cell apoptotic process GO:2000351 24 0.125
regulation of map kinase activity GO:0043405 108 0.121
response to lipopolysaccharide GO:0032496 70 0.117
cellular response to water stimulus GO:0071462 1 0.117
hemopoiesis GO:0030097 180 0.115
negative regulation of response to external stimulus GO:0032102 83 0.115
response to oxygen levels GO:0070482 100 0.115
regulation of cell differentiation GO:0045595 393 0.115
endothelial cell apoptotic process GO:0072577 26 0.114
morphogenesis of an epithelium GO:0002009 60 0.111
cell cycle arrest GO:0007050 71 0.111
cardiovascular system development GO:0072358 262 0.111
t cell selection GO:0045058 4 0.109
negative regulation of protein maturation GO:1903318 142 0.106
negative regulation of catalytic activity GO:0043086 335 0.101
morphogenesis of embryonic epithelium GO:0016331 4 0.101
cellular response to hydrogen peroxide GO:0070301 37 0.101
ubiquitin dependent protein catabolic process GO:0006511 206 0.098
t cell homeostasis GO:0043029 3 0.097
Mouse
response to metal ion GO:0010038 84 0.095
mitotic g1 dna damage checkpoint GO:0031571 17 0.094
leukocyte apoptotic process GO:0071887 31 0.094
Mouse
negative regulation of transport GO:0051051 176 0.094
tyrosine phosphorylation of stat1 protein GO:0042508 11 0.094
mitotic cell cycle GO:0000278 326 0.092
regulation of mitochondrial membrane potential GO:0051881 23 0.092
cellular response to cytokine stimulus GO:0071345 181 0.089
cellular response to radiation GO:0071478 65 0.088
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.088
mitotic dna integrity checkpoint GO:0044774 30 0.087
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.087
response to tumor necrosis factor GO:0034612 76 0.085
regulation of ion transmembrane transport GO:0034765 132 0.084
response to carbohydrate GO:0009743 21 0.084
tetrapyrrole metabolic process GO:0033013 11 0.084
macrophage differentiation GO:0030225 11 0.084
negative regulation of cell cycle GO:0045786 193 0.083
cytokine mediated signaling pathway GO:0019221 109 0.083
substantia nigra development GO:0021762 45 0.083
negative regulation of phosphorus metabolic process GO:0010563 267 0.083
regulation of tumor necrosis factor production GO:0032680 43 0.082
protein catabolic process GO:0030163 325 0.081
response to lipid GO:0033993 206 0.079
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.079
actomyosin structure organization GO:0031032 59 0.077
cellular response to metal ion GO:0071248 43 0.076
actin cytoskeleton organization GO:0030036 207 0.075
head development GO:0060322 108 0.075
positive regulation of kinase activity GO:0033674 204 0.073
regulation of protein transport GO:0051223 213 0.073
response to molecule of bacterial origin GO:0002237 82 0.072
regulation of reactive oxygen species metabolic process GO:2000377 41 0.071
regulation of jak stat cascade GO:0046425 44 0.070
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.070
regulation of intracellular transport of viral material GO:1901252 2 0.069
innate immune response GO:0045087 178 0.069
neural tube formation GO:0001841 3 0.069
tissue morphogenesis GO:0048729 96 0.068
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.068
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.067
spleen development GO:0048536 1 0.067
Mouse
fas signaling pathway GO:0036337 3 0.067
brain development GO:0007420 97 0.065
cell cycle g1 s phase transition GO:0044843 80 0.065
negative regulation of programmed cell death GO:0043069 321 0.064
Mouse
response to biotic stimulus GO:0009607 276 0.064
regulation of response to dna damage stimulus GO:2001020 94 0.063
cell cycle checkpoint GO:0000075 117 0.063
response to other organism GO:0051707 261 0.063
transformed cell apoptotic process GO:0006927 3 0.062
regulation of protein complex assembly GO:0043254 147 0.062
regulation of macrophage differentiation GO:0045649 9 0.061
lymphocyte homeostasis GO:0002260 4 0.060
Mouse
regulation of protein kinase activity GO:0045859 289 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.060
cellular response to uv GO:0034644 32 0.060
cytoplasmic sequestering of nf kappab GO:0007253 7 0.059
negative regulation of phosphate metabolic process GO:0045936 267 0.059
establishment of protein localization to organelle GO:0072594 172 0.058
g1 dna damage checkpoint GO:0044783 18 0.058
cell cell signaling GO:0007267 155 0.057
negative regulation of intracellular transport GO:0032387 60 0.057
regulation of oxidoreductase activity GO:0051341 43 0.056
negative regulation of intracellular transport of viral material GO:1901253 2 0.056
erythrocyte differentiation GO:0030218 28 0.056
t cell differentiation in thymus GO:0033077 4 0.056
Mouse
midbrain development GO:0030901 45 0.055
regulation of ion transport GO:0043269 189 0.054
cytoplasmic transport GO:0016482 379 0.054
positive regulation of cellular component organization GO:0051130 376 0.054
regulation of cell cycle arrest GO:0071156 36 0.054
positive regulation of transport GO:0051050 336 0.054
peptidyl serine autophosphorylation GO:0036289 2 0.053
striated muscle cell differentiation GO:0051146 43 0.053
heart development GO:0007507 95 0.053
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.053
peptidyl tyrosine modification GO:0018212 170 0.053
blood vessel development GO:0001568 172 0.052
anatomical structure formation involved in morphogenesis GO:0048646 284 0.052
regulation of protein deubiquitination GO:0090085 4 0.052
response to bacterium GO:0009617 144 0.051
dephosphorylation GO:0016311 209 0.051
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.051
Mouse
multi organism cellular process GO:0044764 156 0.050
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 13 0.050
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.050
muscle system process GO:0003012 81 0.049
response to toxic substance GO:0009636 37 0.049
tumor necrosis factor production GO:0032640 43 0.048
thymic t cell selection GO:0045061 2 0.048
cellular response to oxidative stress GO:0034599 85 0.048
central nervous system development GO:0007417 123 0.047
response to uv GO:0009411 73 0.047
negative regulation of cell cycle process GO:0010948 121 0.046
cellular response to hypoxia GO:0071456 51 0.046
embryonic epithelial tube formation GO:0001838 4 0.046
neuron death GO:0070997 65 0.046
Mouse
protein heterooligomerization GO:0051291 16 0.045
ion transmembrane transport GO:0034220 338 0.045
cellular response to lithium ion GO:0071285 2 0.045
response to alcohol GO:0097305 64 0.044
response to hexose GO:0009746 20 0.043
regulation of neuron apoptotic process GO:0043523 35 0.042
negative regulation of muscle cell differentiation GO:0051148 17 0.041
cellular response to hormone stimulus GO:0032870 125 0.041
blood vessel morphogenesis GO:0048514 162 0.041
response to estrogen GO:0043627 47 0.041
positive regulation of cell differentiation GO:0045597 211 0.040
positive regulation of osteoclast differentiation GO:0045672 9 0.040
regulation of transferase activity GO:0051338 355 0.040
response to steroid hormone GO:0048545 80 0.039
positive regulation of necroptotic process GO:0060545 2 0.039
regulation of transmembrane transporter activity GO:0022898 74 0.039
maintenance of location GO:0051235 112 0.038
nuclear transport GO:0051169 179 0.038
leukocyte migration GO:0050900 107 0.037
Mouse
negative regulation of striated muscle cell differentiation GO:0051154 8 0.037
mitotic g1 s transition checkpoint GO:0044819 17 0.037
viral process GO:0016032 146 0.036
nucleoside triphosphate metabolic process GO:0009141 422 0.036
positive regulation of cell cycle arrest GO:0071158 23 0.036
signal transduction involved in dna damage checkpoint GO:0072422 15 0.036
myeloid cell differentiation GO:0030099 117 0.036
positive regulation of intracellular protein transport GO:0090316 76 0.035
nervous system development GO:0007399 293 0.035
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.035
oxidation reduction process GO:0055114 396 0.035
multicellular organismal aging GO:0010259 3 0.035
activation of cysteine type endopeptidase activity GO:0097202 57 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
negative regulation of nf kappab import into nucleus GO:0042347 12 0.034
regulation of satellite cell proliferation GO:0014842 1 0.034
response to amino acid GO:0043200 14 0.034
positive regulation of intracellular transport GO:0032388 104 0.034
cellular response to organonitrogen compound GO:0071417 124 0.034
regulation of interleukin 6 production GO:0032675 37 0.034
interleukin 2 secretion GO:0070970 3 0.034
neuron cellular homeostasis GO:0070050 3 0.034
epithelial tube morphogenesis GO:0060562 38 0.033
segmentation GO:0035282 4 0.033
regulation of response to wounding GO:1903034 101 0.033
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.033
protein targeting GO:0006605 187 0.033
organic hydroxy compound metabolic process GO:1901615 147 0.032
regulation of establishment of protein localization GO:0070201 242 0.032
negative regulation of intracellular protein transport GO:0090317 42 0.032
angiogenesis GO:0001525 147 0.032
striated muscle tissue development GO:0014706 59 0.031
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.031
actin filament based process GO:0030029 224 0.031
interleukin 8 production GO:0032637 51 0.031
response to organic cyclic compound GO:0014070 204 0.030
cellular response to steroid hormone stimulus GO:0071383 37 0.030
cellular response to amino acid stimulus GO:0071230 12 0.030
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.030
regeneration GO:0031099 4 0.030
cellular response to inorganic substance GO:0071241 45 0.030
regulation of protein localization GO:0032880 296 0.030
tissue regeneration GO:0042246 3 0.030
positive regulation of cytoplasmic transport GO:1903651 82 0.030
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.030
response to decreased oxygen levels GO:0036293 96 0.028
nucleoside monophosphate metabolic process GO:0009123 191 0.028
regulation of transmembrane transport GO:0034762 139 0.028
regulation of kinase activity GO:0043549 314 0.028
skeletal muscle tissue development GO:0007519 24 0.028
response to wounding GO:0009611 168 0.028
negative regulation of protein phosphorylation GO:0001933 140 0.028
positive regulation of cell cycle process GO:0090068 106 0.027
positive regulation of viral entry into host cell GO:0046598 3 0.027
negative regulation of protein metabolic process GO:0051248 391 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.027
epithelium development GO:0060429 227 0.027
growth of symbiont in host GO:0044117 1 0.027
response to drug GO:0042493 81 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
regulation of osteoclast differentiation GO:0045670 18 0.026
response to lithium ion GO:0010226 2 0.026
oocyte development GO:0048599 1 0.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.026
Mouse
proteasomal protein catabolic process GO:0010498 176 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 2 0.026
positive regulation of interleukin 8 production GO:0032757 36 0.026
cellular response to decreased oxygen levels GO:0036294 51 0.026
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.026
defense response to bacterium GO:0042742 63 0.026
purine nucleoside monophosphate metabolic process GO:0009126 186 0.026
regulation of transporter activity GO:0032409 82 0.025
locomotory behavior GO:0007626 1 0.025
pigment metabolic process GO:0042440 16 0.025
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.025
skeletal muscle organ development GO:0060538 26 0.025
muscle contraction GO:0006936 73 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.024
positive regulation of organelle organization GO:0010638 195 0.024
negative regulation of calcium ion transport GO:0051926 19 0.024
system process GO:0003008 349 0.024
response to organonitrogen compound GO:0010243 156 0.024
determination of adult lifespan GO:0008340 2 0.023
regulation of interleukin 2 secretion GO:1900040 2 0.023
signal transduction in response to dna damage GO:0042770 57 0.023
immune response activating signal transduction GO:0002757 90 0.023
neuron apoptotic process GO:0051402 39 0.023
Mouse
regulation of angiogenesis GO:0045765 92 0.023
negative regulation of cytokine production GO:0001818 82 0.023
protein deubiquitination GO:0016579 79 0.023
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.022
dopamine biosynthetic process GO:0042416 4 0.022
post embryonic development GO:0009791 2 0.022
regulation of neuron death GO:1901214 56 0.021
regulation of calcium ion transport GO:0051924 79 0.021
regulation of mapk cascade GO:0043408 262 0.021
negative regulation of calcium ion import GO:0090281 1 0.021
modification dependent macromolecule catabolic process GO:0043632 212 0.021
negative regulation of catabolic process GO:0009895 104 0.021
response to acid chemical GO:0001101 66 0.021
apoptotic cell clearance GO:0043277 12 0.021
defense response GO:0006952 315 0.021
positive regulation of transferase activity GO:0051347 227 0.021
cellular protein complex assembly GO:0043623 188 0.021
oocyte differentiation GO:0009994 2 0.021
membrane hyperpolarization GO:0060081 1 0.021
response to light stimulus GO:0009416 87 0.021
protein localization to organelle GO:0033365 280 0.020
carbohydrate derivative transport GO:1901264 20 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
protein localization to membrane GO:0072657 160 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
interspecies interaction between organisms GO:0044419 156 0.020
protein targeting to nucleus GO:0044744 104 0.020
positive regulation of immune system process GO:0002684 283 0.020
cellular response to acid chemical GO:0071229 44 0.020
type i interferon production GO:0032606 27 0.020
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.020
myeloid cell homeostasis GO:0002262 34 0.020
cellular response to bacterial lipoprotein GO:0071220 3 0.020
protein import into nucleus GO:0006606 104 0.020
b cell mediated immunity GO:0019724 10 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
adaptive immune response GO:0002250 49 0.019
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
developmental growth GO:0048589 48 0.019
interferon gamma production GO:0032609 39 0.019
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.019
positive regulation of map kinase activity GO:0043406 80 0.019
embryo development GO:0009790 123 0.019
negative regulation of locomotion GO:0040013 118 0.019
negative regulation of cytoplasmic transport GO:1903650 46 0.019
regulation of cytoplasmic transport GO:1903649 149 0.019
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.019
regulation of actin filament length GO:0030832 56 0.019
regulation of membrane potential GO:0042391 95 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.018
signal transduction in absence of ligand GO:0038034 22 0.018
Mouse
chordate embryonic development GO:0043009 34 0.018
response to inorganic substance GO:0010035 127 0.018
myosin filament assembly GO:0031034 2 0.018
ketone catabolic process GO:0042182 3 0.018
chemokine biosynthetic process GO:0042033 4 0.018
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.018
single organism cell adhesion GO:0098602 179 0.018
cellular response to monosaccharide stimulus GO:0071326 10 0.018
negative regulation of cellular catabolic process GO:0031330 83 0.018
activation of innate immune response GO:0002218 55 0.018
regulation of intracellular protein transport GO:0033157 123 0.017
regulation of meiotic cell cycle GO:0051445 4 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
synaptic transmission GO:0007268 61 0.017
organ formation GO:0048645 3 0.017
developmental programmed cell death GO:0010623 3 0.017
negative regulation of multi organism process GO:0043901 92 0.017
viral release from host cell GO:0019076 21 0.017
response to hydrostatic pressure GO:0051599 2 0.017
small molecule catabolic process GO:0044282 92 0.017
protein dephosphorylation GO:0006470 81 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
negative regulation of protein modification process GO:0031400 200 0.016
signal transduction by p53 class mediator GO:0072331 72 0.016
response to growth factor GO:0070848 205 0.016

FADD disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.850
hypersensitivity reaction type iv disease DOID:2916 6 0.841
hypersensitivity reaction disease DOID:0060056 25 0.841
cancer DOID:162 167 0.828
disease of cellular proliferation DOID:14566 174 0.828
organ system cancer DOID:0050686 164 0.711
gastrointestinal system cancer DOID:3119 52 0.166
hepatocellular carcinoma DOID:684 9 0.166
liver carcinoma DOID:686 9 0.166
liver cancer DOID:3571 9 0.166
central nervous system disease DOID:331 186 0.098
nervous system disease DOID:863 431 0.098
respiratory system cancer DOID:0050615 16 0.073
breast cancer DOID:1612 21 0.060
thoracic cancer DOID:5093 21 0.060
neurodegenerative disease DOID:1289 102 0.055
stomach cancer DOID:10534 12 0.050
disease of metabolism DOID:0014667 295 0.030
inherited metabolic disorder DOID:655 242 0.030