Homo sapiens

145 known processes

CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

(Aliases: MTS2,TP15,P15,p15INK4b,CDK4I,INK4B)

CDKN2B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
type b pancreatic cell development GO:0003323 4 0.351
segmentation GO:0035282 4 0.207
small gtpase mediated signal transduction GO:0007264 78 0.186
cell adhesion GO:0007155 325 0.161
regulation of wnt signaling pathway GO:0030111 123 0.160
post embryonic development GO:0009791 2 0.154
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.136
regulation of cell adhesion GO:0030155 166 0.133
negative regulation of cell proliferation GO:0008285 228 0.132
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.128
response to abiotic stimulus GO:0009628 336 0.125
regulation of protein serine threonine kinase activity GO:0071900 179 0.123
protein processing GO:0016485 226 0.123
Mouse
autophagic cell death GO:0048102 3 0.118
regulation of peptidase activity GO:0052547 180 0.116
cellular amine metabolic process GO:0044106 41 0.113
negative regulation of apoptotic process GO:0043066 316 0.112
blastoderm segmentation GO:0007350 2 0.111
response to oxygen containing compound GO:1901700 369 0.110
Mouse
glandular epithelial cell development GO:0002068 5 0.109
regulation of transferase activity GO:0051338 355 0.109
mitochondrion organization GO:0007005 156 0.109
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.108
negative regulation of phosphate metabolic process GO:0045936 267 0.107
regulation of canonical wnt signaling pathway GO:0060828 88 0.104
cell cycle arrest GO:0007050 71 0.104
regulation of cell growth GO:0001558 135 0.104
Mouse
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.103
regulation of cell differentiation GO:0045595 393 0.103
Mouse Rat
negative regulation of catalytic activity GO:0043086 335 0.102
canonical wnt signaling pathway GO:0060070 116 0.101
organ morphogenesis GO:0009887 147 0.100
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.099
regulation of apoptotic signaling pathway GO:2001233 175 0.096
ras protein signal transduction GO:0007265 73 0.096
response to organic cyclic compound GO:0014070 204 0.096
Rat
regulation of kinase activity GO:0043549 314 0.095
regulation of cellular response to stress GO:0080135 244 0.094
negative regulation of programmed cell death GO:0043069 321 0.093
cellular amino acid metabolic process GO:0006520 116 0.092
amine metabolic process GO:0009308 44 0.092
apoptotic signaling pathway GO:0097190 268 0.092
negative regulation of phosphorus metabolic process GO:0010563 267 0.092
cellular ketone metabolic process GO:0042180 80 0.088
cell cycle phase transition GO:0044770 173 0.087
mitotic cell cycle phase transition GO:0044772 162 0.087
epithelium development GO:0060429 227 0.087
Mouse Rat
negative regulation of protein processing GO:0010955 142 0.085
Mouse
negative regulation of developmental process GO:0051093 247 0.084
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.084
biological adhesion GO:0022610 331 0.084
cell growth GO:0016049 160 0.083
Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.082
Mouse
wnt signaling pathway GO:0016055 156 0.080
regulation of nucleotide metabolic process GO:0006140 269 0.080
positive regulation of hydrolase activity GO:0051345 331 0.080
regulation of protein processing GO:0070613 150 0.078
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.078
regulation of cellular amino acid metabolic process GO:0006521 6 0.077
negative regulation of hydrolase activity GO:0051346 182 0.076
negative regulation of proteolysis GO:0045861 132 0.075
Mouse
protein maturation GO:0051604 233 0.075
Mouse
response to radiation GO:0009314 151 0.075
regulation of protein kinase activity GO:0045859 289 0.074
response to hormone GO:0009725 175 0.073
negative regulation of peptidase activity GO:0010466 91 0.073
positive regulation of cellular amine metabolic process GO:0033240 7 0.072
regulation of endopeptidase activity GO:0052548 170 0.072
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
growth GO:0040007 202 0.070
Mouse
negative regulation of protein maturation GO:1903318 142 0.069
Mouse
cardiovascular system development GO:0072358 262 0.069
negative regulation of wnt signaling pathway GO:0030178 69 0.069
negative regulation of phosphorylation GO:0042326 174 0.069
negative regulation of cell growth GO:0030308 83 0.069
Mouse
positive regulation of transferase activity GO:0051347 227 0.068
regulation of cell cycle GO:0051726 393 0.067
regulation of cellular component movement GO:0051270 334 0.067
cell cycle g2 m phase transition GO:0044839 43 0.065
lipid metabolic process GO:0006629 381 0.065
positive regulation of cell proliferation GO:0008284 301 0.065
negative regulation of protein metabolic process GO:0051248 391 0.065
regulation of cell migration GO:0030334 289 0.065
regulation of cell cycle arrest GO:0071156 36 0.064
regulation of response to dna damage stimulus GO:2001020 94 0.064
regulation of locomotion GO:0040012 329 0.063
anatomical structure formation involved in morphogenesis GO:0048646 284 0.063
enteroendocrine cell differentiation GO:0035883 6 0.062
cellular component morphogenesis GO:0032989 314 0.062
cell matrix adhesion GO:0007160 85 0.062
cell activation GO:0001775 213 0.061
Mouse
positive regulation of cellular component organization GO:0051130 376 0.060
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.060
regulation of cell cycle process GO:0010564 266 0.060
regulation of cell matrix adhesion GO:0001952 42 0.060
cell substrate adhesion GO:0031589 132 0.059
regulation of growth GO:0040008 165 0.059
Mouse
stem cell differentiation GO:0048863 93 0.059
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 412 0.058
mitotic cell cycle process GO:1903047 286 0.058
negative regulation of cell differentiation GO:0045596 171 0.058
Mouse
regulation of proteolysis GO:0030162 293 0.056
Mouse
endocrine system development GO:0035270 26 0.056
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.056
regulation of cell motility GO:2000145 299 0.055
negative regulation of endopeptidase activity GO:0010951 84 0.055
regulation of cell substrate adhesion GO:0010810 68 0.055
vasculature development GO:0001944 181 0.055
multicellular organismal aging GO:0010259 3 0.054
epithelial cell differentiation GO:0030855 141 0.053
Rat
regeneration GO:0031099 4 0.053
morphogenesis of embryonic epithelium GO:0016331 4 0.052
circulatory system development GO:0072359 262 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.050
negative regulation of cell cycle GO:0045786 193 0.050
positive regulation of phosphorylation GO:0042327 394 0.050
enzyme linked receptor protein signaling pathway GO:0007167 303 0.050
positive regulation of protein phosphorylation GO:0001934 313 0.050
system process GO:0003008 349 0.049
positive regulation of developmental process GO:0051094 314 0.048
Mouse Rat
positive regulation of cell cycle GO:0045787 140 0.047
g2 m transition of mitotic cell cycle GO:0000086 41 0.047
cellular macromolecule catabolic process GO:0044265 380 0.047
Mouse
signal transduction by phosphorylation GO:0023014 297 0.047
cell development GO:0048468 328 0.047
Mouse
positive regulation of cell cycle process GO:0090068 106 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
negative regulation of cell adhesion GO:0007162 64 0.046
regulation of reactive oxygen species metabolic process GO:2000377 41 0.046
regulation of ossification GO:0030278 58 0.045
purine ribonucleoside catabolic process GO:0046130 398 0.045
regulation of anatomical structure morphogenesis GO:0022603 286 0.045
Mouse
oxidation reduction process GO:0055114 396 0.044
determination of adult lifespan GO:0008340 2 0.044
cytoplasmic transport GO:0016482 379 0.044
Mouse
epithelial cell proliferation GO:0050673 128 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.044
regulation of mapk cascade GO:0043408 262 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.043
mitotic cell cycle GO:0000278 326 0.043
cellular response to endogenous stimulus GO:0071495 336 0.043
protein catabolic process GO:0030163 325 0.042
Mouse
positive regulation of programmed cell death GO:0043068 249 0.042
Mouse
response to external biotic stimulus GO:0043207 261 0.042
ribonucleoside catabolic process GO:0042454 406 0.042
dephosphorylation GO:0016311 209 0.042
positive regulation of immune system process GO:0002684 283 0.041
blood vessel development GO:0001568 172 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
positive regulation of wnt signaling pathway GO:0030177 54 0.041
regulation of cysteine type endopeptidase activity GO:2000116 127 0.041
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.041
nucleoside triphosphate metabolic process GO:0009141 422 0.041
negative regulation of protein phosphorylation GO:0001933 140 0.040
female gamete generation GO:0007292 2 0.040
negative regulation of intracellular signal transduction GO:1902532 183 0.040
positive regulation of cell adhesion GO:0045785 84 0.040
response to growth factor GO:0070848 205 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
positive regulation of protein kinase activity GO:0045860 190 0.039
regulation of phosphatase activity GO:0010921 81 0.039
positive regulation of apoptotic process GO:0043065 246 0.039
Mouse
regulation of protein localization GO:0032880 296 0.038
nucleotide catabolic process GO:0009166 408 0.038
nucleoside phosphate catabolic process GO:1901292 412 0.038
cell morphogenesis GO:0000902 296 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.038
positive regulation of catabolic process GO:0009896 310 0.038
specification of organ identity GO:0010092 3 0.037
dna repair GO:0006281 198 0.037
motor neuron axon guidance GO:0008045 2 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
actin filament based process GO:0030029 224 0.037
intrinsic apoptotic signaling pathway GO:0097193 127 0.037
response to lipid GO:0033993 206 0.037
rho protein signal transduction GO:0007266 26 0.037
negative regulation of protein modification process GO:0031400 200 0.036
immune response GO:0006955 307 0.036
organophosphate biosynthetic process GO:0090407 163 0.036
negative regulation of epithelial cell proliferation GO:0050680 48 0.036
regulation of immune response GO:0050776 201 0.036
negative regulation of immune system process GO:0002683 136 0.036
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.036
Mouse
response to other organism GO:0051707 261 0.035
regulation of protein maturation GO:1903317 150 0.035
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.035
negative regulation of cell death GO:0060548 345 0.035
transmembrane transport GO:0055085 399 0.035
regulation of mitotic cell cycle GO:0007346 189 0.035
purine nucleoside catabolic process GO:0006152 398 0.035
t cell differentiation in thymus GO:0033077 4 0.035
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.035
Mouse
positive regulation of kinase activity GO:0033674 204 0.034
pituitary gland development GO:0021983 2 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
response to transforming growth factor beta GO:0071559 94 0.034
ion homeostasis GO:0050801 230 0.034
cell cycle g1 s phase transition GO:0044843 80 0.034
Mouse
ossification GO:0001503 121 0.034
organonitrogen compound biosynthetic process GO:1901566 200 0.033
hematopoietic or lymphoid organ development GO:0048534 186 0.033
nucleoside catabolic process GO:0009164 408 0.033
regulation of establishment of protein localization GO:0070201 242 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
Mouse
epithelial cell development GO:0002064 34 0.033
organophosphate catabolic process GO:0046434 430 0.033
organ formation GO:0048645 3 0.033
response to cytokine GO:0034097 232 0.033
Rat
type b pancreatic cell differentiation GO:0003309 5 0.032
positive regulation of organelle organization GO:0010638 195 0.032
nucleoside monophosphate metabolic process GO:0009123 191 0.032
negative regulation of kinase activity GO:0033673 106 0.032
positive regulation of transport GO:0051050 336 0.032
negative regulation of cell cycle phase transition GO:1901988 89 0.032
cardiac muscle cell contraction GO:0086003 4 0.032
regulation of cell morphogenesis GO:0022604 153 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
cell projection organization GO:0030030 252 0.031
cellular lipid metabolic process GO:0044255 303 0.031
negative regulation of protein kinase activity GO:0006469 98 0.031
oogenesis GO:0048477 2 0.031
response to oxidative stress GO:0006979 121 0.031
Mouse
cardiac cell fate determination GO:0060913 3 0.030
positive regulation of cell substrate adhesion GO:0010811 37 0.030
positive regulation of cell death GO:0010942 263 0.030
Mouse
response to organonitrogen compound GO:0010243 156 0.030
response to nutrient levels GO:0031667 81 0.030
chemical homeostasis GO:0048878 306 0.030
Mouse
ribonucleotide catabolic process GO:0009261 405 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
fibroblast proliferation GO:0048144 33 0.030
response to metal ion GO:0010038 84 0.030
regulation of cell cycle phase transition GO:1901987 126 0.030
chemotaxis GO:0006935 157 0.029
hemopoiesis GO:0030097 180 0.029
intracellular protein transport GO:0006886 270 0.029
morphogenesis of a polarized epithelium GO:0001738 3 0.029
locomotory behavior GO:0007626 1 0.029
peptidyl tyrosine phosphorylation GO:0018108 170 0.029
regulation of cellular component biogenesis GO:0044087 281 0.029
mapk cascade GO:0000165 288 0.029
purine containing compound catabolic process GO:0072523 411 0.029
cell aging GO:0007569 52 0.029
Mouse
negative regulation of growth GO:0045926 97 0.029
Mouse
myeloid cell differentiation GO:0030099 117 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.028
protein localization to organelle GO:0033365 280 0.028
cell fate determination GO:0001709 3 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.028
single organism cellular localization GO:1902580 332 0.028
anterior posterior axis specification GO:0009948 2 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
osteoblast differentiation GO:0001649 92 0.028
regulation of protein catabolic process GO:0042176 155 0.028
Mouse
response to drug GO:0042493 81 0.028
blood vessel morphogenesis GO:0048514 162 0.027
ion transmembrane transport GO:0034220 338 0.027
notch signaling pathway GO:0007219 31 0.027
g1 s transition of mitotic cell cycle GO:0000082 78 0.027
Mouse
hindbrain development GO:0030902 3 0.027
reactive oxygen species metabolic process GO:0072593 75 0.026
neuron fate commitment GO:0048663 2 0.026
nucleocytoplasmic transport GO:0006913 176 0.026
Mouse
pattern specification involved in kidney development GO:0061004 1 0.026
negative regulation of transferase activity GO:0051348 124 0.026
sensory perception GO:0007600 103 0.026
lymphocyte activation GO:0046649 133 0.026
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
Mouse
response to biotic stimulus GO:0009607 276 0.026
positive regulation of endopeptidase activity GO:0010950 84 0.026
neurological system process GO:0050877 163 0.026
hair follicle morphogenesis GO:0031069 2 0.025
regulation of response to external stimulus GO:0032101 222 0.025
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.025
regulation of cell proliferation involved in kidney development GO:1901722 3 0.025
cation transport GO:0006812 331 0.025
regulation of cytokine production GO:0001817 232 0.025
establishment of planar polarity GO:0001736 3 0.025
tube development GO:0035295 125 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
neurogenesis GO:0022008 169 0.025
tube morphogenesis GO:0035239 95 0.025
angiogenesis GO:0001525 147 0.025
nervous system development GO:0007399 293 0.025
spinal cord development GO:0021510 4 0.025
cation transmembrane transport GO:0098655 238 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
Mouse Rat
sensory perception of sound GO:0007605 37 0.025
membrane organization GO:0061024 292 0.024
negative regulation of cellular amine metabolic process GO:0033239 3 0.024
response to nitrogen compound GO:1901698 184 0.024
regulation of nucleoside metabolic process GO:0009118 209 0.024
cranial nerve development GO:0021545 4 0.024
regulation of myeloid cell differentiation GO:0045637 81 0.024
regulation of intracellular transport GO:0032386 195 0.024
Mouse
urogenital system development GO:0001655 65 0.024
anion transport GO:0006820 161 0.024
stem cell development GO:0048864 69 0.024
Mouse
nitrogen compound transport GO:0071705 191 0.024
nerve development GO:0021675 4 0.024
gtp catabolic process GO:0006184 237 0.024
tripartite regional subdivision GO:0007351 2 0.024
secretion by cell GO:0032940 226 0.023
positive regulation of cell migration GO:0030335 172 0.023
single organism membrane organization GO:0044802 268 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
Mouse
regulation of intracellular protein transport GO:0033157 123 0.023
negative regulation of transport GO:0051051 176 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.023
neuromuscular junction development GO:0007528 3 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
peptidyl tyrosine modification GO:0018212 170 0.023
response to extracellular stimulus GO:0009991 85 0.023
regulation of ras protein signal transduction GO:0046578 155 0.023
adult locomotory behavior GO:0008344 1 0.023
nucleotide biosynthetic process GO:0009165 109 0.023
positive regulation of locomotion GO:0040017 186 0.023
negative regulation of cellular component movement GO:0051271 106 0.023
mitotic nuclear division GO:0007067 119 0.022
negative regulation of apoptotic signaling pathway GO:2001234 97 0.022
glandular epithelial cell differentiation GO:0002067 6 0.022
leukocyte activation GO:0045321 164 0.022
Mouse
secretion GO:0046903 254 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
negative regulation of locomotion GO:0040013 118 0.022
vesicle mediated transport GO:0016192 371 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
apoptotic mitochondrial changes GO:0008637 57 0.022
regulation of hormone levels GO:0010817 125 0.022
cellular response to cytokine stimulus GO:0071345 181 0.022
anterior posterior axis specification embryo GO:0008595 2 0.022
cation homeostasis GO:0055080 189 0.022
defense response GO:0006952 315 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.022
heart formation GO:0060914 2 0.022
organic anion transport GO:0015711 103 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.021
regulation of cell cycle g2 m phase transition GO:1902749 22 0.021
regulation of response to wounding GO:1903034 101 0.021
embryo development GO:0009790 123 0.021
positive regulation of odontogenesis GO:0042482 3 0.021
rhythmic behavior GO:0007622 2 0.021
response to oxygen levels GO:0070482 100 0.021
renal system development GO:0072001 63 0.021
organelle fission GO:0048285 149 0.021
response to steroid hormone GO:0048545 80 0.021
head development GO:0060322 108 0.021
cellular homeostasis GO:0019725 196 0.021
cyclic nucleotide metabolic process GO:0009187 82 0.020
regulation of dna metabolic process GO:0051052 153 0.020
atp metabolic process GO:0046034 176 0.020
neural tube formation GO:0001841 3 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.020
peripheral nervous system development GO:0007422 2 0.020
positive regulation of cytokine production GO:0001819 167 0.020
regulation of protein transport GO:0051223 213 0.020
single organism cell adhesion GO:0098602 179 0.020
protein localization to nucleus GO:0034504 136 0.020
neural crest cell development GO:0014032 3 0.020
regulation of secretion GO:0051046 194 0.020
organic hydroxy compound metabolic process GO:1901615 147 0.020
endocrine pancreas development GO:0031018 11 0.020
protein ubiquitination GO:0016567 314 0.020
Mouse
cell differentiation in spinal cord GO:0021515 1 0.020
regulation of defense response GO:0031347 154 0.020
blood circulation GO:0008015 113 0.020
positive regulation of cell motility GO:2000147 177 0.020
endomembrane system organization GO:0010256 196 0.020
actin mediated cell contraction GO:0070252 12 0.020
regulation of homeostatic process GO:0032844 121 0.020
cell part morphogenesis GO:0032990 137 0.020
response to uv GO:0009411 73 0.019
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.019
regulation of dephosphorylation GO:0035303 96 0.019
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
behavior GO:0007610 112 0.019
skeletal system development GO:0001501 79 0.019
response to wounding GO:0009611 168 0.019
extrinsic apoptotic signaling pathway GO:0097191 119 0.019
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
lipid biosynthetic process GO:0008610 177 0.019
response to ionizing radiation GO:0010212 65 0.019
primary neural tube formation GO:0014020 3 0.019
cellular response to abiotic stimulus GO:0071214 117 0.019
immune system development GO:0002520 195 0.019
taxis GO:0042330 157 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
cellular response to external stimulus GO:0071496 111 0.019
cellular response to organic cyclic compound GO:0071407 127 0.019
regulation of ion transport GO:0043269 189 0.019
carbohydrate metabolic process GO:0005975 207 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
response to virus GO:0009615 126 0.019
compound eye development GO:0048749 1 0.019
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.019
Mouse
salivary gland morphogenesis GO:0007435 4 0.019
positive regulation of cellular component movement GO:0051272 181 0.019
actin filament based movement GO:0030048 17 0.019
embryonic forelimb morphogenesis GO:0035115 4 0.018
endocytosis GO:0006897 159 0.018
response to light stimulus GO:0009416 87 0.018
hematopoietic progenitor cell differentiation GO:0002244 38 0.018
regulation of actin filament based process GO:0032970 141 0.018
positive regulation of response to external stimulus GO:0032103 88 0.018
monocarboxylic acid metabolic process GO:0032787 185 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
actin cytoskeleton organization GO:0030036 207 0.018
pharynx development GO:0060465 1 0.018
ameboidal type cell migration GO:0001667 135 0.018
positive regulation of immune response GO:0050778 159 0.018
gtp metabolic process GO:0046039 239 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.018
regulation of mitochondrion organization GO:0010821 54 0.018
memory GO:0007613 3 0.018
negative regulation of dephosphorylation GO:0035305 63 0.018
negative regulation of phosphatase activity GO:0010923 61 0.018
regulation of neurotransmitter secretion GO:0046928 3 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
stress activated protein kinase signaling cascade GO:0031098 94 0.018
nuclear division GO:0000280 128 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
regulation of neural precursor cell proliferation GO:2000177 4 0.018
pattern specification process GO:0007389 43 0.018
regulation of ion transmembrane transport GO:0034765 132 0.018
regulation of cell development GO:0060284 161 0.018
Mouse
reactive nitrogen species metabolic process GO:2001057 3 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
signal transduction by p53 class mediator GO:0072331 72 0.017
regulation of transmembrane transporter activity GO:0022898 74 0.017
chromatin organization GO:0006325 351 0.017
prostate gland development GO:0030850 3 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of osteoblast differentiation GO:0045667 38 0.017
positive regulation of proteolysis GO:0045862 142 0.017
regulation of ion homeostasis GO:2000021 73 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
Mouse
sequestering of metal ion GO:0051238 24 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
response to inorganic substance GO:0010035 127 0.017
Mouse
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.017
Mouse
negative regulation of gliogenesis GO:0014014 3 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
regulation of transmembrane transport GO:0034762 139 0.017
somitogenesis GO:0001756 2 0.017
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.017
cellular cation homeostasis GO:0030003 163 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
mesenchyme development GO:0060485 59 0.017
protein localization to membrane GO:0072657 160 0.017
regulation of gtpase activity GO:0043087 180 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.017
gabaergic neuron differentiation GO:0097154 1 0.017
myoblast fusion GO:0007520 1 0.017
regulation of cellular response to growth factor stimulus GO:0090287 76 0.017
reproductive system development GO:0061458 56 0.017
negative regulation of catabolic process GO:0009895 104 0.017
Mouse
regulation of cellular senescence GO:2000772 13 0.016
mesenchymal cell development GO:0014031 50 0.016
regulation of cell activation GO:0050865 125 0.016
Mouse
chromatin assembly GO:0031497 61 0.016
negative regulation of mitotic cell cycle GO:0045930 102 0.016
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.016
regulation of small gtpase mediated signal transduction GO:0051056 156 0.016
inner ear morphogenesis GO:0042472 4 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.016
forebrain generation of neurons GO:0021872 3 0.016
response to magnesium ion GO:0032026 3 0.016
neurotransmitter secretion GO:0007269 4 0.016
protein import into nucleus GO:0006606 104 0.016

CDKN2B disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.057
disease of cellular proliferation DOID:14566 174 0.057
organ system cancer DOID:0050686 164 0.042
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
disease of metabolism DOID:0014667 295 0.025
musculoskeletal system disease DOID:17 223 0.022
bone disease DOID:0080001 88 0.022
connective tissue disease DOID:65 109 0.022
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.018
central nervous system disease DOID:331 186 0.017
gastrointestinal system cancer DOID:3119 52 0.017