Homo sapiens

94 known processes

BARD1

BRCA1 associated RING domain 1

BARD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 198 0.987
Human
cellular response to dna damage stimulus GO:0006974 379 0.921
Human
covalent chromatin modification GO:0016569 254 0.849
internal protein amino acid acetylation GO:0006475 101 0.799
oogenesis GO:0048477 2 0.770
purine nucleoside triphosphate metabolic process GO:0009144 412 0.699
chromatin modification GO:0016568 298 0.657
internal peptidyl lysine acetylation GO:0018393 97 0.657
peptidyl lysine acetylation GO:0018394 101 0.565
blastocyst development GO:0001824 3 0.555
regulation of dna metabolic process GO:0051052 153 0.520
response to radiation GO:0009314 151 0.498
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.468
organelle fission GO:0048285 149 0.458
regulation of cell cycle GO:0051726 393 0.412
response to ionizing radiation GO:0010212 65 0.407
ribonucleoside catabolic process GO:0042454 406 0.401
cellular macromolecule catabolic process GO:0044265 380 0.371
cell development GO:0048468 328 0.360
double strand break repair GO:0006302 101 0.344
Human
female gamete generation GO:0007292 2 0.333
post embryonic development GO:0009791 2 0.330
histone modification GO:0016570 251 0.299
regulation of cellular amino acid metabolic process GO:0006521 6 0.296
nervous system development GO:0007399 293 0.267
nucleoside triphosphate metabolic process GO:0009141 422 0.255
histone acetylation GO:0016573 93 0.253
regulation of gene expression epigenetic GO:0040029 73 0.252
purine ribonucleoside catabolic process GO:0046130 398 0.239
peptidyl lysine modification GO:0018205 144 0.237
purine nucleoside triphosphate catabolic process GO:0009146 392 0.223
ribonucleoside triphosphate metabolic process GO:0009199 412 0.221
ribonucleotide catabolic process GO:0009261 405 0.213
purine containing compound catabolic process GO:0072523 411 0.213
purine nucleotide catabolic process GO:0006195 405 0.196
nucleoside triphosphate catabolic process GO:0009143 394 0.186
response to organic cyclic compound GO:0014070 204 0.183
cellular amino acid metabolic process GO:0006520 116 0.178
protein acylation GO:0043543 138 0.174
double strand break repair via homologous recombination GO:0000724 50 0.169
Human
rna processing GO:0006396 255 0.165
protein acetylation GO:0006473 116 0.160
chromatin organization GO:0006325 351 0.153
male meiosis GO:0007140 1 0.148
negative regulation of mitotic cell cycle GO:0045930 102 0.147
response to abiotic stimulus GO:0009628 336 0.145
regulation of cellular amine metabolic process GO:0033238 11 0.139
generation of neurons GO:0048699 152 0.139
double strand break repair via single strand annealing GO:0045002 4 0.135
g2 dna damage checkpoint GO:0031572 26 0.129
histone h4 acetylation GO:0043967 47 0.124
reproductive process GO:0022414 106 0.123
Rat
cell projection organization GO:0030030 252 0.122
neurogenesis GO:0022008 169 0.121
embryo development GO:0009790 123 0.117
response to uv GO:0009411 73 0.116
growth GO:0040007 202 0.113
regulation of cellular ketone metabolic process GO:0010565 50 0.113
histone h4 k5 acetylation GO:0043981 15 0.113
amine metabolic process GO:0009308 44 0.113
cellular amine metabolic process GO:0044106 41 0.111
signal transduction in response to dna damage GO:0042770 57 0.110
dna damage response signal transduction resulting in transcription GO:0042772 12 0.108
purine ribonucleotide catabolic process GO:0009154 404 0.106
negative regulation of cell cycle GO:0045786 193 0.106
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.105
atp catabolic process GO:0006200 157 0.103
purine nucleoside monophosphate catabolic process GO:0009128 158 0.103
regulation of cell cycle phase transition GO:1901987 126 0.101
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.100
nucleoside phosphate catabolic process GO:1901292 412 0.098
immune system development GO:0002520 195 0.095
histone h4 k12 acetylation GO:0043983 6 0.095
response to steroid hormone GO:0048545 80 0.093
ras protein signal transduction GO:0007265 73 0.093
nucleotide catabolic process GO:0009166 408 0.092
mitotic cell cycle GO:0000278 326 0.090
response to hormone GO:0009725 175 0.088
ribonucleoside triphosphate catabolic process GO:0009203 391 0.087
positive regulation of cell proliferation GO:0008284 301 0.087
histone h3 acetylation GO:0043966 45 0.085
mitotic cell cycle process GO:1903047 286 0.084
purine nucleoside catabolic process GO:0006152 398 0.084
cell morphogenesis GO:0000902 296 0.083
organophosphate catabolic process GO:0046434 430 0.082
development of primary sexual characteristics GO:0045137 35 0.082
embryo development ending in birth or egg hatching GO:0009792 34 0.081
response to light stimulus GO:0009416 87 0.081
neuron differentiation GO:0030182 138 0.080
negative regulation of cell cycle phase transition GO:1901988 89 0.078
oocyte differentiation GO:0009994 2 0.078
protein modification by small protein conjugation GO:0032446 342 0.076
cellular response to organic cyclic compound GO:0071407 127 0.074
protein catabolic process GO:0030163 325 0.072
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.071
dna replication GO:0006260 116 0.069
Human
regulation of dna repair GO:0006282 47 0.069
meiotic chromosome segregation GO:0045132 4 0.068
anatomical structure formation involved in morphogenesis GO:0048646 284 0.068
determination of adult lifespan GO:0008340 2 0.067
cell part morphogenesis GO:0032990 137 0.067
response to nitrogen compound GO:1901698 184 0.066
dna damage checkpoint GO:0000077 68 0.066
recombinational repair GO:0000725 50 0.066
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.064
nucleoside monophosphate metabolic process GO:0009123 191 0.064
apoptotic signaling pathway GO:0097190 268 0.063
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.063
single organism reproductive process GO:0044702 98 0.062
Rat
reproductive structure development GO:0048608 55 0.062
modification dependent protein catabolic process GO:0019941 209 0.062
gene silencing GO:0016458 49 0.061
proteasomal protein catabolic process GO:0010498 176 0.060
endocytosis GO:0006897 159 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.056
cytoplasmic transport GO:0016482 379 0.056
maintenance of location GO:0051235 112 0.056
regionalization GO:0003002 29 0.054
protein localization to organelle GO:0033365 280 0.054
positive regulation of chromosome organization GO:2001252 41 0.054
dna recombination GO:0006310 77 0.054
Human
isotype switching GO:0045190 3 0.053
posttranscriptional regulation of gene expression GO:0010608 213 0.053
guanosine containing compound metabolic process GO:1901068 244 0.051
dna integrity checkpoint GO:0031570 71 0.050
cellular component morphogenesis GO:0032989 314 0.050
cytokinesis GO:0000910 96 0.049
ribonucleoside monophosphate catabolic process GO:0009158 158 0.049
regulation of growth GO:0040008 165 0.049
receptor mediated endocytosis GO:0006898 84 0.048
positive regulation of organelle organization GO:0010638 195 0.048
regulation of protein acetylation GO:1901983 25 0.048
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.048
cell type specific apoptotic process GO:0097285 125 0.048
regulation of peptidyl lysine acetylation GO:2000756 22 0.048
regulation of meiosis GO:0040020 3 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
regulation of cell cycle process GO:0010564 266 0.047
mrna metabolic process GO:0016071 175 0.047
cellular response to endogenous stimulus GO:0071495 336 0.047
rna interference GO:0016246 4 0.046
cellular protein catabolic process GO:0044257 261 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.045
atp metabolic process GO:0046034 176 0.045
regulation of protein catabolic process GO:0042176 155 0.045
regulation of protein kinase activity GO:0045859 289 0.045
modification dependent macromolecule catabolic process GO:0043632 212 0.045
response to oxidative stress GO:0006979 121 0.044
multicellular organism reproduction GO:0032504 42 0.044
Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.044
intracellular protein transport GO:0006886 270 0.043
neuron development GO:0048666 113 0.043
cellular response to abiotic stimulus GO:0071214 117 0.042
regulation of response to dna damage stimulus GO:2001020 94 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.042
pattern specification process GO:0007389 43 0.042
regulation of cell division GO:0051302 116 0.041
leukocyte mediated immunity GO:0002443 59 0.041
developmental process involved in reproduction GO:0003006 66 0.041
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.040
positive regulation of gtpase activity GO:0043547 166 0.040
signal transduction by phosphorylation GO:0023014 297 0.040
negative regulation of multicellular organismal process GO:0051241 317 0.040
negative regulation of apoptotic process GO:0043066 316 0.039
intrinsic apoptotic signaling pathway GO:0097193 127 0.039
positive regulation of dna metabolic process GO:0051054 73 0.039
negative regulation of developmental process GO:0051093 247 0.038
positive regulation of nucleoside metabolic process GO:0045979 186 0.038
spindle midzone assembly GO:0051255 4 0.038
response to oxygen containing compound GO:1901700 369 0.038
negative regulation of cell death GO:0060548 345 0.038
positive regulation of transport GO:0051050 336 0.036
regulation of chromatin modification GO:1903308 51 0.035
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.035
enzyme linked receptor protein signaling pathway GO:0007167 303 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
developmental growth GO:0048589 48 0.035
purine nucleoside monophosphate metabolic process GO:0009126 186 0.035
regulation of histone acetylation GO:0035065 19 0.035
regulation of mitotic cell cycle GO:0007346 189 0.034
multicellular organismal aging GO:0010259 3 0.034
negative regulation of protein processing GO:0010955 142 0.034
response to inorganic substance GO:0010035 127 0.034
sex differentiation GO:0007548 45 0.034
small molecule biosynthetic process GO:0044283 157 0.034
meiosis i GO:0007127 4 0.034
regulation of histone modification GO:0031056 47 0.033
positive regulation of protein transport GO:0051222 135 0.033
negative regulation of protein metabolic process GO:0051248 391 0.033
ubiquitin dependent protein catabolic process GO:0006511 206 0.033
nucleoside monophosphate catabolic process GO:0009125 159 0.033
dicarboxylic acid biosynthetic process GO:0043650 4 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.031
cellular response to oxygen containing compound GO:1901701 276 0.031
reproduction GO:0000003 63 0.031
Rat
carboxylic acid biosynthetic process GO:0046394 97 0.030
dna replication independent nucleosome assembly GO:0006336 27 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
telomere maintenance GO:0000723 32 0.030
oocyte development GO:0048599 1 0.029
mitotic dna integrity checkpoint GO:0044774 30 0.028
negative regulation of protein modification process GO:0031400 200 0.028
regulation of gtpase activity GO:0043087 180 0.028
histone h3 k9 modification GO:0061647 11 0.028
locomotory behavior GO:0007626 1 0.028
meiotic cell cycle GO:0051321 13 0.028
glycosyl compound catabolic process GO:1901658 413 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
regulation of meiotic cell cycle GO:0051445 4 0.027
positive regulation of hydrolase activity GO:0051345 331 0.027
cellular response to oxidative stress GO:0034599 85 0.027
single organism cellular localization GO:1902580 332 0.027
regeneration GO:0031099 4 0.027
segmentation GO:0035282 4 0.027
oocyte maturation GO:0001556 1 0.026
positive regulation of response to dna damage stimulus GO:2001022 43 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
non recombinational repair GO:0000726 14 0.026
regulation of protein localization GO:0032880 296 0.026
regulation of cellular response to stress GO:0080135 244 0.026
actin filament based process GO:0030029 224 0.026
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.025
cell fate determination GO:0001709 3 0.025
neuron projection development GO:0031175 106 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.025
regulation of double strand break repair GO:2000779 22 0.025
microtubule cytoskeleton organization GO:0000226 176 0.025
regulation of small gtpase mediated signal transduction GO:0051056 156 0.025
cellular ketone metabolic process GO:0042180 80 0.025
dna double strand break processing GO:0000729 10 0.025
mitotic dna replication checkpoint GO:0033314 2 0.024
hemopoiesis GO:0030097 180 0.024
negative regulation of proteolysis GO:0045861 132 0.024
nuclear division GO:0000280 128 0.024
negative regulation of protein maturation GO:1903318 142 0.023
monocarboxylic acid biosynthetic process GO:0072330 67 0.023
response to estrogen GO:0043627 47 0.023
response to calcium ion GO:0051592 46 0.023
chromosome segregation GO:0007059 114 0.023
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.023
regulation of transferase activity GO:0051338 355 0.023
cell projection morphogenesis GO:0048858 129 0.023
regulation of cytokine production GO:0001817 232 0.022
sex determination GO:0007530 3 0.022
interstrand cross link repair GO:0036297 3 0.022
chordate embryonic development GO:0043009 34 0.022
positive regulation of intracellular transport GO:0032388 104 0.022
nucleoside catabolic process GO:0009164 408 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
reproductive system development GO:0061458 56 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
dna catabolic process GO:0006308 49 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
regulation of protein processing GO:0070613 150 0.020
compound eye development GO:0048749 1 0.020
epithelial cell differentiation GO:0030855 141 0.020
vesicle mediated transport GO:0016192 371 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
response to lipid GO:0033993 206 0.020
dna methylation or demethylation GO:0044728 19 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
regulation of protein maturation GO:1903317 150 0.019
response to wounding GO:0009611 168 0.019
response to transforming growth factor beta GO:0071559 94 0.019
fatty acid biosynthetic process GO:0006633 46 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.019
positive regulation of dna repair GO:0045739 25 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.018
regulation of kinase activity GO:0043549 314 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
g1 s transition of mitotic cell cycle GO:0000082 78 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
protein import into nucleus GO:0006606 104 0.018
telomere organization GO:0032200 33 0.018
regulation of cell migration GO:0030334 289 0.018
protein targeting GO:0006605 187 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
amino acid import GO:0043090 4 0.018
regulation of apoptotic signaling pathway GO:2001233 175 0.018
small gtpase mediated signal transduction GO:0007264 78 0.017
head development GO:0060322 108 0.017
Human
cellular response to growth factor stimulus GO:0071363 197 0.017
protein processing GO:0016485 226 0.017
lipid localization GO:0010876 106 0.017
regulation of locomotion GO:0040012 329 0.017
response to alcohol GO:0097305 64 0.017
regulation of cellular component movement GO:0051270 334 0.017
response to growth factor GO:0070848 205 0.016
negative regulation of histone h3 k9 methylation GO:0051573 3 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
behavior GO:0007610 112 0.016
immune response GO:0006955 307 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
neuron apoptotic process GO:0051402 39 0.016
negative regulation of cell proliferation GO:0008285 228 0.016
nuclear transcribed mrna catabolic process GO:0000956 48 0.016
regulation of response to external stimulus GO:0032101 222 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
microtubule organizing center organization GO:0031023 62 0.015
positive regulation of intracellular protein transport GO:0090316 76 0.015
histone lysine methylation GO:0034968 50 0.015
chromosome separation GO:0051304 23 0.015
dna dependent dna replication GO:0006261 44 0.015
Human
response to estradiol GO:0032355 23 0.014
regulation of chromatin organization GO:1902275 56 0.014
neuron projection morphogenesis GO:0048812 50 0.014
immune effector process GO:0002252 159 0.014
establishment of nucleus localization GO:0040023 1 0.013
regulation of dna replication GO:0006275 68 0.013
protein methylation GO:0006479 74 0.013
regulation of centrosome duplication GO:0010824 14 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
mrna catabolic process GO:0006402 56 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
protein maturation GO:0051604 233 0.013
nucleotide excision repair GO:0006289 31 0.013
positive regulation of histone acetylation GO:0035066 11 0.013
gtp catabolic process GO:0006184 237 0.013
gtp metabolic process GO:0046039 239 0.013
nuclear import GO:0051170 106 0.013
centrosome organization GO:0051297 58 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
positive regulation of catabolic process GO:0009896 310 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
secretion GO:0046903 254 0.012
mitotic centrosome separation GO:0007100 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
innate immune response GO:0045087 178 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
defense response GO:0006952 315 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
positive regulation of chromatin modification GO:1903310 30 0.012
cytokine production GO:0001816 247 0.012
mitotic nuclear division GO:0007067 119 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
positive regulation of histone modification GO:0031058 29 0.012
regulation of cell growth GO:0001558 135 0.012
blood circulation GO:0008015 113 0.012
ameboidal type cell migration GO:0001667 135 0.012
regulation of chromosome organization GO:0033044 103 0.011
regulation of intracellular transport GO:0032386 195 0.011
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.011
methylation GO:0032259 106 0.011
sexual reproduction GO:0019953 37 0.011
Rat
regulation of double strand break repair via homologous recombination GO:0010569 11 0.011
single organism nuclear import GO:1902593 104 0.011
regulation of cell shape GO:0008360 48 0.011
l amino acid import GO:0043092 4 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
protein autophosphorylation GO:0046777 123 0.011
oxidation reduction process GO:0055114 396 0.011
regulation of centrosome cycle GO:0046605 15 0.011
nucleoside phosphate biosynthetic process GO:1901293 109 0.011
cellular amide metabolic process GO:0043603 69 0.011
cell division GO:0051301 168 0.011
positive regulation of cell cycle GO:0045787 140 0.011
secretion by cell GO:0032940 226 0.011
posttranscriptional gene silencing by rna GO:0035194 25 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
cellular response to estrogen stimulus GO:0071391 16 0.011
maintenance of dna repeat elements GO:0043570 4 0.011
cellular response to radiation GO:0071478 65 0.011
response to hypoxia GO:0001666 96 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.011
associative learning GO:0008306 1 0.011
negative regulation of epidermal cell differentiation GO:0045605 4 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.011
spermatid development GO:0007286 4 0.010
leukocyte activation involved in immune response GO:0002366 30 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
cellular response to steroid hormone stimulus GO:0071383 37 0.010
regulation of cellular response to growth factor stimulus GO:0090287 76 0.010
negative regulation of protein catabolic process GO:0042177 59 0.010
multicellular organismal reproductive process GO:0048609 40 0.010
Rat

BARD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.798
disease of cellular proliferation DOID:14566 174 0.798
immune system disease DOID:2914 155 0.394
hematopoietic system disease DOID:74 100 0.394
organ system cancer DOID:0050686 164 0.373
endocrine gland cancer DOID:170 26 0.229
pancreatic cancer DOID:1793 8 0.172
breast cancer DOID:1612 21 0.080
thoracic cancer DOID:5093 21 0.080
reproductive organ cancer DOID:193 23 0.064
aplastic anemia DOID:12449 30 0.047
bone marrow disease DOID:4961 31 0.047
anemia DOID:2355 55 0.047
congenital hypoplastic anemia DOID:1342 26 0.023