Homo sapiens

0 known processes

EDEM1

ER degradation enhancer, mannosidase alpha-like 1

(Aliases: FLJ51559,KIAA0212,EDEM,FLJ51560)

EDEM1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.094
thyroid hormone transport GO:0070327 2 0.079
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
cellular amino acid metabolic process GO:0006520 116 0.066
regulation of cellular ketone metabolic process GO:0010565 50 0.065
cation transport GO:0006812 331 0.064
amine metabolic process GO:0009308 44 0.064
cellular amine metabolic process GO:0044106 41 0.061
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.049
Mouse
modification dependent protein catabolic process GO:0019941 209 0.048
Mouse
post embryonic development GO:0009791 2 0.047
response to hormone GO:0009725 175 0.046
response to lipid GO:0033993 206 0.046
glycoprotein metabolic process GO:0009100 110 0.045
carbohydrate derivative biosynthetic process GO:1901137 207 0.043
cellular ketone metabolic process GO:0042180 80 0.042
ubiquitin dependent protein catabolic process GO:0006511 206 0.042
Mouse
intracellular protein transport GO:0006886 270 0.041
determination of adult lifespan GO:0008340 2 0.038
cellular macromolecule catabolic process GO:0044265 380 0.038
Mouse
macromolecule glycosylation GO:0043413 63 0.038
ribonucleotide catabolic process GO:0009261 405 0.038
response to organic cyclic compound GO:0014070 204 0.038
cellular response to lipid GO:0071396 127 0.037
ribonucleoside catabolic process GO:0042454 406 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.035
cellular response to organic cyclic compound GO:0071407 127 0.035
nucleoside triphosphate catabolic process GO:0009143 394 0.035
protein catabolic process GO:0030163 325 0.034
Mouse
metal ion transport GO:0030001 272 0.034
g protein coupled receptor signaling pathway GO:0007186 207 0.033
regulation of transferase activity GO:0051338 355 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.032
response to external biotic stimulus GO:0043207 261 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
response to other organism GO:0051707 261 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
protein glycosylation GO:0006486 62 0.031
cytoplasmic transport GO:0016482 379 0.031
single organism cellular localization GO:1902580 332 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
lipid metabolic process GO:0006629 381 0.030
transmembrane transport GO:0055085 399 0.029
response to abiotic stimulus GO:0009628 336 0.029
defense response GO:0006952 315 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
cellular protein catabolic process GO:0044257 261 0.028
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.028
response to biotic stimulus GO:0009607 276 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
Mouse
regulation of protein kinase activity GO:0045859 289 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.027
Mouse
immune response GO:0006955 307 0.026
multicellular organismal aging GO:0010259 3 0.026
nucleotide catabolic process GO:0009166 408 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.025
female gamete generation GO:0007292 2 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
divalent metal ion transport GO:0070838 152 0.024
carbohydrate metabolic process GO:0005975 207 0.024
nitrogen compound transport GO:0071705 191 0.024
nucleoside catabolic process GO:0009164 408 0.024
anion transport GO:0006820 161 0.024
regulation of kinase activity GO:0043549 314 0.024
positive regulation of apoptotic process GO:0043065 246 0.023
cellular response to hormone stimulus GO:0032870 125 0.023
regulation of proteolysis GO:0030162 293 0.023
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.023
positive regulation of protein phosphorylation GO:0001934 313 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
regulation of locomotion GO:0040012 329 0.023
protein maturation GO:0051604 233 0.022
response to steroid hormone GO:0048545 80 0.022
regulation of protein localization GO:0032880 296 0.022
positive regulation of cellular component movement GO:0051272 181 0.022
protein targeting GO:0006605 187 0.022
actin filament based process GO:0030029 224 0.022
response to oxygen containing compound GO:1901700 369 0.022
apoptotic signaling pathway GO:0097190 268 0.021
divalent inorganic cation transport GO:0072511 158 0.021
response to growth factor GO:0070848 205 0.021
response to organonitrogen compound GO:0010243 156 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
positive regulation of cell death GO:0010942 263 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.020
organic anion transport GO:0015711 103 0.020
positive regulation of immune system process GO:0002684 283 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
response to decreased oxygen levels GO:0036293 96 0.020
regulation of cellular component movement GO:0051270 334 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
positive regulation of transport GO:0051050 336 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
maintenance of location GO:0051235 112 0.020
negative regulation of proteolysis GO:0045861 132 0.020
response to bacterium GO:0009617 144 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
Mouse
dephosphorylation GO:0016311 209 0.020
purine containing compound catabolic process GO:0072523 411 0.020
positive regulation of cell motility GO:2000147 177 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
ras protein signal transduction GO:0007265 73 0.019
positive regulation of catabolic process GO:0009896 310 0.019
chemical homeostasis GO:0048878 306 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.019
positive regulation of cell migration GO:0030335 172 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.018
ion transmembrane transport GO:0034220 338 0.018
locomotory behavior GO:0007626 1 0.018
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
regulation of mesonephros development GO:0061217 3 0.018
regulation of ion transport GO:0043269 189 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
calcium ion homeostasis GO:0055074 122 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
response to metal ion GO:0010038 84 0.018
glycosylation GO:0070085 71 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
regulation of intracellular transport GO:0032386 195 0.018
cation transmembrane transport GO:0098655 238 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.017
negative regulation of protein modification process GO:0031400 200 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
oxidation reduction process GO:0055114 396 0.017
gtp catabolic process GO:0006184 237 0.017
regulation of gtp catabolic process GO:0033124 180 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
response to estrogen GO:0043627 47 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
positive regulation of transferase activity GO:0051347 227 0.017
response to nitrogen compound GO:1901698 184 0.017
epithelium development GO:0060429 227 0.017
system process GO:0003008 349 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
negative regulation of phosphorylation GO:0042326 174 0.016
regulation of protein processing GO:0070613 150 0.016
single organism membrane organization GO:0044802 268 0.016
response to cytokine GO:0034097 232 0.016
segmentation GO:0035282 4 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
organophosphate catabolic process GO:0046434 430 0.016
cellular response to endogenous stimulus GO:0071495 336 0.015
regulation of cell motility GO:2000145 299 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
regulation of homeostatic process GO:0032844 121 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
mitotic cell cycle GO:0000278 326 0.015
mitotic cell cycle process GO:1903047 286 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
response to inorganic substance GO:0010035 127 0.015
cell cycle phase transition GO:0044770 173 0.015
regulation of peptidase activity GO:0052547 180 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
synaptic vesicle recycling GO:0036465 3 0.015
protein processing GO:0016485 226 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
regulation of cell migration GO:0030334 289 0.015
atp metabolic process GO:0046034 176 0.015
neuromuscular junction development GO:0007528 3 0.015
secretion GO:0046903 254 0.015
negative regulation of protein processing GO:0010955 142 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
memory GO:0007613 3 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of epithelial cell migration GO:0010632 93 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
glycoprotein biosynthetic process GO:0009101 91 0.014
peripheral nervous system development GO:0007422 2 0.014
hindbrain development GO:0030902 3 0.014
negative regulation of cell cycle GO:0045786 193 0.014
chromatin modification GO:0016568 298 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
oogenesis GO:0048477 2 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of gtpase activity GO:0043087 180 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
positive regulation of locomotion GO:0040017 186 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
carboxylic acid transport GO:0046942 63 0.013
steroid metabolic process GO:0008202 94 0.013
regulation of response to external stimulus GO:0032101 222 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
regulation of protein transport GO:0051223 213 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
negative regulation of cell death GO:0060548 345 0.013
regeneration GO:0031099 4 0.013
compound eye development GO:0048749 1 0.013
protein localization to membrane GO:0072657 160 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
embryonic epithelial tube formation GO:0001838 4 0.013
regulation of endothelial cell migration GO:0010594 67 0.013
calcium ion transport GO:0006816 147 0.013
spermatid differentiation GO:0048515 4 0.013
regulation of cell cycle process GO:0010564 266 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
innate immune response GO:0045087 178 0.013
small molecule biosynthetic process GO:0044283 157 0.013
regulation of cell cycle GO:0051726 393 0.013
nuclear transport GO:0051169 179 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
rna interference GO:0016246 4 0.013
endosomal transport GO:0016197 129 0.013
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
tissue morphogenesis GO:0048729 96 0.013
biological adhesion GO:0022610 331 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.013
regulation of cellular response to growth factor stimulus GO:0090287 76 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
regulation of secretion GO:0051046 194 0.013
interspecies interaction between organisms GO:0044419 156 0.013
epithelial cell differentiation GO:0030855 141 0.013
gtp metabolic process GO:0046039 239 0.013
cell growth GO:0016049 160 0.012
regulation of defense response GO:0031347 154 0.012
negative regulation of protein maturation GO:1903318 142 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
regulation of cellular response to stress GO:0080135 244 0.012
growth GO:0040007 202 0.012
cellular response to estrogen stimulus GO:0071391 16 0.012
vesicle mediated transport GO:0016192 371 0.012
rho protein signal transduction GO:0007266 26 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
regulation of protein maturation GO:1903317 150 0.012
organic acid transport GO:0015849 65 0.012
adult locomotory behavior GO:0008344 1 0.012
cell adhesion GO:0007155 325 0.012
epithelium migration GO:0090132 119 0.012
blastoderm segmentation GO:0007350 2 0.012
cellular lipid metabolic process GO:0044255 303 0.012
positive regulation of mesonephros development GO:0061213 2 0.012
regulation of immune response GO:0050776 201 0.012
eye photoreceptor cell differentiation GO:0001754 2 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
protein localization to organelle GO:0033365 280 0.012
sequestering of metal ion GO:0051238 24 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
regulation of mapk cascade GO:0043408 262 0.012
leukocyte activation GO:0045321 164 0.012
regulation of ion homeostasis GO:2000021 73 0.012
positive regulation of kinase activity GO:0033674 204 0.012
urogenital system development GO:0001655 65 0.012
response to fungus GO:0009620 4 0.012
associative learning GO:0008306 1 0.012
negative regulation of transport GO:0051051 176 0.012
chromatin organization GO:0006325 351 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
negative regulation of catabolic process GO:0009895 104 0.011
spermatid development GO:0007286 4 0.011
rhythmic behavior GO:0007622 2 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
oocyte development GO:0048599 1 0.011
mrna metabolic process GO:0016071 175 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
inner ear morphogenesis GO:0042472 4 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
lipid transport GO:0006869 90 0.011
neuroblast proliferation GO:0007405 4 0.011
ameboidal type cell migration GO:0001667 135 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
metencephalon development GO:0022037 2 0.011
endomembrane system organization GO:0010256 196 0.011
anterior posterior axis specification GO:0009948 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
regulation of metal ion transport GO:0010959 120 0.011
response to hypoxia GO:0001666 96 0.011
motor neuron axon guidance GO:0008045 2 0.011
ion homeostasis GO:0050801 230 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
immune effector process GO:0002252 159 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of hormone levels GO:0010817 125 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
response to oxygen levels GO:0070482 100 0.011
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.011
membrane organization GO:0061024 292 0.011
positive regulation of cytokine production GO:0001819 167 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.010
dna repair GO:0006281 198 0.010
metal ion homeostasis GO:0055065 169 0.010
lipid modification GO:0030258 84 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.010
cell activation GO:0001775 213 0.010
cell morphogenesis GO:0000902 296 0.010
response to virus GO:0009615 126 0.010
mapk cascade GO:0000165 288 0.010
atp catabolic process GO:0006200 157 0.010
positive regulation of developmental process GO:0051094 314 0.010
regulation of protein complex assembly GO:0043254 147 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
regulation of growth GO:0040008 165 0.010
endocytosis GO:0006897 159 0.010
protein targeting to nucleus GO:0044744 104 0.010
epithelial cell migration GO:0010631 119 0.010
cell fate determination GO:0001709 3 0.010
eye pigmentation GO:0048069 1 0.010
nervous system development GO:0007399 293 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
negative regulation of transferase activity GO:0051348 124 0.010
activation of protein kinase activity GO:0032147 90 0.010
positive regulation of protein transport GO:0051222 135 0.010
organelle assembly GO:0070925 176 0.010
positive regulation of mapk cascade GO:0043410 190 0.010

EDEM1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.036
inherited metabolic disorder DOID:655 242 0.036
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.022
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
musculoskeletal system disease DOID:17 223 0.017
sensory system disease DOID:0050155 203 0.015
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
retinal disease DOID:5679 118 0.012
connective tissue disease DOID:65 109 0.011
neurodegenerative disease DOID:1289 102 0.011