|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.444
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.358
|
Mouse |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.269
|
Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.266
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.255
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.233
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.226
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.213
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.201
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.182
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.177
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.172
|
Mouse |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.170
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.169
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.167
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.164
|
Mouse |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.154
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.150
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.149
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.148
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.137
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.137
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.135
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.134
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.133
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.132
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.132
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.130
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.128
|
Fly |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.128
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.124
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.120
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.116
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.116
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.114
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.114
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.114
|
Mouse |
|
|
segmentation
|
GO:0035282 |
4 |
0.113
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.112
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.109
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.109
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.109
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.108
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.107
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.107
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.106
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.106
|
|
|
|
memory
|
GO:0007613 |
3 |
0.105
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.104
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.102
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.102
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.101
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.099
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.099
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.098
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.096
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.096
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.096
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.094
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.092
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.090
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.088
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.088
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.087
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.087
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.087
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.086
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.085
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.083
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.083
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.083
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.083
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.082
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.082
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.081
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.080
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.078
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.076
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.074
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.073
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.072
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.072
|
Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.072
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.072
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.071
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.070
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.069
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.069
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.069
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.068
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.068
|
|
|
|
system process
|
GO:0003008 |
349 |
0.067
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.066
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.066
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.066
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.065
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.065
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.064
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.064
|
Mouse Fly |
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.064
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.064
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.064
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.063
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.061
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.061
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.060
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.060
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.060
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.059
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.059
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.058
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.058
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.058
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.058
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.057
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.057
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.057
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.056
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.056
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.055
|
Fly |
|
|
response to hormone
|
GO:0009725 |
175 |
0.055
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.054
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.054
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.054
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.054
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.053
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.053
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.053
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.053
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.052
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.052
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.052
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.051
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.050
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.050
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.050
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.050
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.049
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.049
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.049
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.048
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.048
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.048
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.048
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.048
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.048
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.047
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.046
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.046
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.046
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.046
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.046
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.046
|
Mouse |
|
|
long term memory
|
GO:0007616 |
2 |
0.046
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.045
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.045
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.045
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.045
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.045
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.045
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.045
|
|
|
|
growth
|
GO:0040007 |
202 |
0.044
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.044
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.043
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.043
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.043
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.043
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.043
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.043
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.043
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.043
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.043
|
|
|
|
head development
|
GO:0060322 |
108 |
0.043
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.043
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.043
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.042
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.042
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.042
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.042
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.041
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.041
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.041
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.041
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.041
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.041
|
Human Fly |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.041
|
Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.041
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.040
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.040
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.040
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.040
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.040
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.039
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.039
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.038
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.038
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.038
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.038
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.038
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.038
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.038
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.038
|
Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.038
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.037
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.037
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.037
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.037
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.037
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.037
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.037
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.037
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.037
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.037
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.036
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.036
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.036
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.036
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.036
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.036
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.036
|
Fly |
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.036
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.035
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.035
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.035
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.035
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.035
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.035
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.035
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.035
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.034
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.034
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.034
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.034
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.033
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.033
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.033
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.033
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.032
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.032
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.032
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.032
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.032
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.032
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.032
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.032
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.032
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.032
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.032
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.031
|
Human |
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.030
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.030
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.030
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.030
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.029
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.029
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.029
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.029
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.029
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.029
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.029
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.029
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.028
|
Mouse |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.028
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.028
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.028
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.028
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.028
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.028
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.027
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.027
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.027
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.027
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.027
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.027
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.027
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.027
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.027
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.027
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.027
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.027
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.026
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.026
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.026
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.026
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.026
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.026
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.026
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.026
|
Fly |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.026
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.026
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.026
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.026
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.026
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.025
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.025
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.025
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.025
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.025
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.025
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.025
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.025
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.025
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.025
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.025
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.024
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.024
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.024
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.024
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.024
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.024
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.024
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.024
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.024
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.024
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.024
|
Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.024
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.024
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.023
|
|
|
|
cgmp catabolic process
|
GO:0046069 |
3 |
0.023
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.023
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.023
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.023
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.023
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.023
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.023
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.023
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.023
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.023
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.023
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.023
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.023
|
Human |
|
|
regionalization
|
GO:0003002 |
29 |
0.023
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.023
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.023
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.022
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.022
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.022
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.022
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.022
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.022
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.022
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.022
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.022
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.022
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.022
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.022
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.022
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
3 |
0.022
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.022
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.022
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.022
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.022
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.022
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.022
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.022
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.021
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.021
|
Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.021
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.021
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.021
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.021
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.021
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.021
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.021
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.021
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.021
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.021
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.021
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.021
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.021
|
Human |
|
|
oocyte development
|
GO:0048599 |
1 |
0.021
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.021
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.021
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.021
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.021
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.020
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.020
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.020
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.020
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.020
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.020
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.020
|
Mouse |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.020
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.020
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.020
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.020
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.019
|
Human |
|
|
response to insulin
|
GO:0032868 |
45 |
0.019
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.019
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.019
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.019
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.019
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.019
|
Human |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.019
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.019
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.019
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.019
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.019
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.019
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.018
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.018
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.018
|
Fly |
|
|
kidney development
|
GO:0001822 |
53 |
0.018
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.018
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.018
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.018
|
|
|
|
renal tubule development
|
GO:0061326 |
19 |
0.018
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.018
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.018
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.018
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.018
|
Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.018
|
Mouse |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.018
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.018
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.018
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.018
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.018
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.018
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.018
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.018
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.018
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.018
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.018
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.018
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.018
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.018
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.017
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.017
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.017
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.017
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.017
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.017
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.017
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.017
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.017
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.017
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.017
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.017
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.017
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.017
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.017
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.017
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.017
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.017
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.017
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.017
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.017
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.017
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.017
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.017
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.017
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.017
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.017
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.017
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.017
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.017
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.016
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.016
|
|
|
|
camp metabolic process
|
GO:0046058 |
61 |
0.016
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.016
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.016
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.016
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.016
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.016
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.016
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.016
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.016
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.016
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.016
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.016
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.016
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.016
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.016
|
Human |
