Homo sapiens

0 known processes

THAP2

THAP domain containing, apoptosis associated protein 2

(Aliases: DKFZp564I0422)

THAP2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of natural killer cell proliferation GO:0032817 4 0.399
natural killer cell activation GO:0030101 12 0.243
negative regulation of t cell receptor signaling pathway GO:0050860 4 0.229
natural killer cell proliferation GO:0001787 4 0.119
tissue regeneration GO:0042246 3 0.095
regeneration GO:0031099 4 0.093
immune response GO:0006955 307 0.088
morphogenesis of a polarized epithelium GO:0001738 3 0.069
nucleoside triphosphate metabolic process GO:0009141 422 0.069
positive regulation of immune response GO:0050778 159 0.068
cellular amine metabolic process GO:0044106 41 0.068
positive regulation of immune system process GO:0002684 283 0.068
nucleoside phosphate catabolic process GO:1901292 412 0.064
dephosphorylation GO:0016311 209 0.063
regulation of immune response GO:0050776 201 0.063
positive regulation of cellular catabolic process GO:0031331 284 0.060
positive regulation of catabolic process GO:0009896 310 0.058
regulation of cellular amino acid metabolic process GO:0006521 6 0.056
organophosphate catabolic process GO:0046434 430 0.055
glycosyl compound catabolic process GO:1901658 413 0.055
positive regulation of developmental process GO:0051094 314 0.054
purine ribonucleoside metabolic process GO:0046128 437 0.050
purine containing compound catabolic process GO:0072523 411 0.049
neuromuscular junction development GO:0007528 3 0.049
digestive tract development GO:0048565 75 0.046
biological adhesion GO:0022610 331 0.046
cellular ketone metabolic process GO:0042180 80 0.046
establishment of tissue polarity GO:0007164 3 0.045
response to wounding GO:0009611 168 0.044
protein dephosphorylation GO:0006470 81 0.044
post embryonic development GO:0009791 2 0.042
hard palate development GO:0060022 1 0.042
nucleoside triphosphate catabolic process GO:0009143 394 0.042
blood circulation GO:0008015 113 0.041
organonitrogen compound biosynthetic process GO:1901566 200 0.041
system process GO:0003008 349 0.040
cell adhesion GO:0007155 325 0.040
positive regulation of gtpase activity GO:0043547 166 0.038
regulation of cell activation GO:0050865 125 0.038
multicellular organismal aging GO:0010259 3 0.037
regulation of nucleotide metabolic process GO:0006140 269 0.037
amine metabolic process GO:0009308 44 0.037
regulation of mononuclear cell proliferation GO:0032944 65 0.036
protein catabolic process GO:0030163 325 0.036
transmembrane transport GO:0055085 399 0.036
single organism cell adhesion GO:0098602 179 0.035
activation of immune response GO:0002253 114 0.034
peptidyl tyrosine dephosphorylation GO:0035335 36 0.034
inorganic ion transmembrane transport GO:0098660 231 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.033
response to growth factor GO:0070848 205 0.033
regulation of cell development GO:0060284 161 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
wnt signaling pathway GO:0016055 156 0.032
cellular macromolecule catabolic process GO:0044265 380 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.031
oogenesis GO:0048477 2 0.031
regulation of transmembrane transport GO:0034762 139 0.031
cell activation GO:0001775 213 0.031
ribonucleoside catabolic process GO:0042454 406 0.031
purine nucleotide catabolic process GO:0006195 405 0.031
regulation of lymphocyte activation GO:0051249 103 0.031
regulation of kinase activity GO:0043549 314 0.029
nucleotide catabolic process GO:0009166 408 0.029
positive regulation of cellular component biogenesis GO:0044089 158 0.029
nucleoside catabolic process GO:0009164 408 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
ion transmembrane transport GO:0034220 338 0.028
cellular component morphogenesis GO:0032989 314 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
rho protein signal transduction GO:0007266 26 0.027
hematopoietic or lymphoid organ development GO:0048534 186 0.027
cell morphogenesis GO:0000902 296 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
negative regulation of immune system process GO:0002683 136 0.026
regulation of natural killer cell activation GO:0032814 9 0.026
determination of adult lifespan GO:0008340 2 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.026
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
endosomal transport GO:0016197 129 0.026
segmentation GO:0035282 4 0.026
regulation of cellular component biogenesis GO:0044087 281 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
regulation of cell differentiation GO:0045595 393 0.025
locomotory behavior GO:0007626 1 0.025
protein localization to organelle GO:0033365 280 0.025
carbohydrate derivative biosynthetic process GO:1901137 207 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.025
t cell activation GO:0042110 99 0.025
epithelium development GO:0060429 227 0.024
g protein coupled receptor signaling pathway GO:0007186 207 0.024
metal ion transport GO:0030001 272 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
regulation of protein localization GO:0032880 296 0.024
cell development GO:0048468 328 0.024
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
cellular macromolecular complex assembly GO:0034622 324 0.023
cellular protein catabolic process GO:0044257 261 0.023
female gamete generation GO:0007292 2 0.023
regulation of cellular ketone metabolic process GO:0010565 50 0.023
inner ear morphogenesis GO:0042472 4 0.023
purine nucleoside catabolic process GO:0006152 398 0.023
tube development GO:0035295 125 0.023
immune response activating signal transduction GO:0002757 90 0.022
regulation of cellular response to stress GO:0080135 244 0.022
cation transmembrane transport GO:0098655 238 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
positive regulation of protein kinase activity GO:0045860 190 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
mitotic cell cycle GO:0000278 326 0.021
Human
regulation of gtp catabolic process GO:0033124 180 0.021
regulation of cell motility GO:2000145 299 0.021
t cell receptor signaling pathway GO:0050852 21 0.021
nervous system development GO:0007399 293 0.021
regulation of transferase activity GO:0051338 355 0.021
positive regulation of hydrolase activity GO:0051345 331 0.021
memory GO:0007613 3 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
cellular amino acid metabolic process GO:0006520 116 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
monovalent inorganic cation transport GO:0015672 128 0.021
cell growth GO:0016049 160 0.021
rna processing GO:0006396 255 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
negative regulation of protein modification process GO:0031400 200 0.020
regulation of transmembrane transporter activity GO:0022898 74 0.020
negative regulation of leukocyte activation GO:0002695 26 0.020
sodium ion transmembrane transport GO:0035725 59 0.020
actin filament based process GO:0030029 224 0.020
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
digestive tract morphogenesis GO:0048546 56 0.019
intracellular protein transport GO:0006886 270 0.019
response to abiotic stimulus GO:0009628 336 0.019
single organism cellular localization GO:1902580 332 0.019
oocyte differentiation GO:0009994 2 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
response to oxygen containing compound GO:1901700 369 0.019
digestive system development GO:0055123 75 0.019
positive regulation of proteolysis GO:0045862 142 0.019
cation transport GO:0006812 331 0.019
blastoderm segmentation GO:0007350 2 0.018
regulation of leukocyte activation GO:0002694 115 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of protein transport GO:0051223 213 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
regulation of cell cycle process GO:0010564 266 0.018
neurological system process GO:0050877 163 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
regulation of gtpase activity GO:0043087 180 0.018
regulation of cell growth GO:0001558 135 0.018
ras protein signal transduction GO:0007265 73 0.018
positive regulation of cell adhesion GO:0045785 84 0.018
glycoprotein metabolic process GO:0009100 110 0.017
retrograde transport endosome to golgi GO:0042147 45 0.017
regulation of lymphocyte proliferation GO:0050670 64 0.017
regulation of ras protein signal transduction GO:0046578 155 0.017
lipid metabolic process GO:0006629 381 0.017
otic vesicle development GO:0071599 1 0.017
cardiac muscle contraction GO:0060048 34 0.017
peptide metabolic process GO:0006518 51 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
glycoprotein biosynthetic process GO:0009101 91 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
actin cytoskeleton organization GO:0030036 207 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
cell matrix adhesion GO:0007160 85 0.017
actin filament organization GO:0007015 128 0.017
oocyte development GO:0048599 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
sodium ion transport GO:0006814 61 0.017
secretion by cell GO:0032940 226 0.017
mitotic cell cycle process GO:1903047 286 0.017
regulation of ion transport GO:0043269 189 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
innate immune response GO:0045087 178 0.016
organelle assembly GO:0070925 176 0.016
heart process GO:0003015 62 0.016
cell projection assembly GO:0030031 126 0.016
regulation of neuron differentiation GO:0045664 70 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
regulation of mapk cascade GO:0043408 262 0.016
chemical homeostasis GO:0048878 306 0.016
protein targeting GO:0006605 187 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
positive regulation of transport GO:0051050 336 0.016
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
immune response regulating signaling pathway GO:0002764 97 0.015
regulation of t cell activation GO:0050863 77 0.015
actin filament based movement GO:0030048 17 0.015
ion homeostasis GO:0050801 230 0.015
membrane organization GO:0061024 292 0.015
regulation of cell matrix adhesion GO:0001952 42 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
response to biotic stimulus GO:0009607 276 0.015
embryo development GO:0009790 123 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
negative regulation of protein metabolic process GO:0051248 391 0.015
regulation of antigen receptor mediated signaling pathway GO:0050854 10 0.014
gtp metabolic process GO:0046039 239 0.014
negative regulation of transferase activity GO:0051348 124 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
regulation of dna metabolic process GO:0051052 153 0.014
regulation of proteolysis GO:0030162 293 0.014
actin mediated cell contraction GO:0070252 12 0.014
inorganic cation transmembrane transport GO:0098662 194 0.014
epithelium migration GO:0090132 119 0.014
regulation of leukocyte proliferation GO:0070663 67 0.014
positive regulation of nervous system development GO:0051962 54 0.014
positive regulation of cytokine production GO:0001819 167 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
adult locomotory behavior GO:0008344 1 0.014
cellular ion homeostasis GO:0006873 168 0.014
neuron development GO:0048666 113 0.014
cation homeostasis GO:0055080 189 0.014
cell migration involved in gastrulation GO:0042074 1 0.014
circulatory system process GO:0003013 113 0.014
microtubule based process GO:0007017 210 0.014
defense response GO:0006952 315 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
cellular cation homeostasis GO:0030003 163 0.013
generation of neurons GO:0048699 152 0.013
regulation of intracellular transport GO:0032386 195 0.013
lymphocyte activation GO:0046649 133 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
response to inorganic substance GO:0010035 127 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
positive regulation of cell death GO:0010942 263 0.013
neurotransmitter secretion GO:0007269 4 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
anterior posterior axis specification GO:0009948 2 0.013
cell projection organization GO:0030030 252 0.013
muscle system process GO:0003012 81 0.013
lymphocyte proliferation GO:0046651 70 0.013
single organism membrane organization GO:0044802 268 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
positive regulation of organelle organization GO:0010638 195 0.013
ectodermal placode formation GO:0060788 1 0.013
endomembrane system organization GO:0010256 196 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
Human
apoptotic signaling pathway GO:0097190 268 0.013
regulation of ion transmembrane transporter activity GO:0032412 72 0.013
protein maturation GO:0051604 233 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
response to external biotic stimulus GO:0043207 261 0.013
tube morphogenesis GO:0035239 95 0.013
response to nitrogen compound GO:1901698 184 0.012
growth GO:0040007 202 0.012
muscle contraction GO:0006936 73 0.012
myoblast fusion GO:0007520 1 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
ameboidal type cell migration GO:0001667 135 0.012
cellular protein complex assembly GO:0043623 188 0.012
negative regulation of t cell activation GO:0050868 18 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of cell cycle GO:0045786 193 0.012
protein ubiquitination GO:0016567 314 0.012
positive regulation of transferase activity GO:0051347 227 0.012
rhythmic behavior GO:0007622 2 0.012
regulation of cytokine production GO:0001817 232 0.012
response to cytokine GO:0034097 232 0.012
response to oxidative stress GO:0006979 121 0.012
positive regulation of protein catabolic process GO:0045732 75 0.012
regulation of dephosphorylation GO:0035303 96 0.012
calcium ion transport GO:0006816 147 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of protein stability GO:0031647 87 0.012
protein localization to nucleus GO:0034504 136 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
carbohydrate metabolic process GO:0005975 207 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
mononuclear cell proliferation GO:0032943 71 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
chemotaxis GO:0006935 157 0.011
regulation of protein processing GO:0070613 150 0.011
fatty acid metabolic process GO:0006631 115 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
blood vessel morphogenesis GO:0048514 162 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
spermatid development GO:0007286 4 0.011
regulation of cell cycle GO:0051726 393 0.011
Human
lipid biosynthetic process GO:0008610 177 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
positive regulation of cell development GO:0010720 92 0.011
protein autophosphorylation GO:0046777 123 0.011
protein processing GO:0016485 226 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
hindbrain development GO:0030902 3 0.011
heart contraction GO:0060047 62 0.011
divalent inorganic cation transport GO:0072511 158 0.011
cellular lipid metabolic process GO:0044255 303 0.011
metencephalon development GO:0022037 2 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
g1 s transition of mitotic cell cycle GO:0000082 78 0.011
sensory perception of pain GO:0019233 4 0.011
negative regulation of cell growth GO:0030308 83 0.011
tripartite regional subdivision GO:0007351 2 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
cell division GO:0051301 168 0.011
regulation of phosphatase activity GO:0010921 81 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
response to organonitrogen compound GO:0010243 156 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
single organism nuclear import GO:1902593 104 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
compound eye development GO:0048749 1 0.011
protein oligomerization GO:0051259 173 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
reproductive process GO:0022414 106 0.010
sulfur compound metabolic process GO:0006790 101 0.010
cellular response to oxidative stress GO:0034599 85 0.010
negative regulation of b cell receptor signaling pathway GO:0050859 2 0.010
ncrna processing GO:0034470 83 0.010
maintenance of location GO:0051235 112 0.010
positive regulation of cell cycle GO:0045787 140 0.010
nuclear transport GO:0051169 179 0.010
negative regulation of organelle organization GO:0010639 126 0.010
ectodermal placode development GO:0071696 1 0.010
small molecule biosynthetic process GO:0044283 157 0.010
cilium assembly GO:0042384 63 0.010
protein secretion GO:0009306 98 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
cellular response to organonitrogen compound GO:0071417 124 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
mating GO:0007618 1 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
anion transport GO:0006820 161 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
regulation of cell adhesion GO:0030155 166 0.010
plasma membrane organization GO:0007009 115 0.010
peptidyl lysine modification GO:0018205 144 0.010
gtp catabolic process GO:0006184 237 0.010
regulation of binding GO:0051098 111 0.010
regulation of system process GO:0044057 101 0.010
regulation of epithelial cell migration GO:0010632 93 0.010

THAP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.082
disease of cellular proliferation DOID:14566 174 0.082
organ system cancer DOID:0050686 164 0.082
disease of metabolism DOID:0014667 295 0.061
inherited metabolic disorder DOID:655 242 0.050
gastrointestinal system cancer DOID:3119 52 0.043
metal metabolism disorder DOID:896 19 0.031
central nervous system disease DOID:331 186 0.019
nervous system disease DOID:863 431 0.019
large intestine cancer DOID:5672 29 0.018
colon cancer DOID:219 25 0.018
intestinal cancer DOID:10155 29 0.018
colorectal cancer DOID:9256 29 0.018
sensory system disease DOID:0050155 203 0.018
musculoskeletal system disease DOID:17 223 0.016
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
retinal disease DOID:5679 118 0.012
colon carcinoma DOID:1520 25 0.012
disease of mental health DOID:150 70 0.011