Homo sapiens

6 known processes

SGSH

N-sulfoglucosamine sulfohydrolase

(Aliases: SFMD,HSS,MPS3A)

SGSH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.099
post embryonic development GO:0009791 2 0.089
cellular amino acid metabolic process GO:0006520 116 0.075
regulation of cellular amine metabolic process GO:0033238 11 0.072
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
determination of adult lifespan GO:0008340 2 0.067
multicellular organismal aging GO:0010259 3 0.066
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.066
regulation of cellular ketone metabolic process GO:0010565 50 0.065
single organism carbohydrate metabolic process GO:0044723 193 0.063
amine metabolic process GO:0009308 44 0.062
locomotory behavior GO:0007626 1 0.061
carbohydrate metabolic process GO:0005975 207 0.060
cellular ketone metabolic process GO:0042180 80 0.058
small gtpase mediated signal transduction GO:0007264 78 0.058
positive regulation of cellular amine metabolic process GO:0033240 7 0.057
neurological system process GO:0050877 163 0.048
carbohydrate derivative biosynthetic process GO:1901137 207 0.042
cytoplasmic transport GO:0016482 379 0.041
ras protein signal transduction GO:0007265 73 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
glycosyl compound catabolic process GO:1901658 413 0.039
cellular macromolecule catabolic process GO:0044265 380 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
nervous system development GO:0007399 293 0.037
protein catabolic process GO:0030163 325 0.036
lipid metabolic process GO:0006629 381 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
positive regulation of phosphorylation GO:0042327 394 0.034
regulation of gtp catabolic process GO:0033124 180 0.034
regulation of purine nucleotide metabolic process GO:1900542 264 0.034
regulation of kinase activity GO:0043549 314 0.034
oxidation reduction process GO:0055114 396 0.033
cellular homeostasis GO:0019725 196 0.032
cell projection organization GO:0030030 252 0.032
actin filament based process GO:0030029 224 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
modification dependent protein catabolic process GO:0019941 209 0.032
ubiquitin dependent protein catabolic process GO:0006511 206 0.031
ribonucleotide catabolic process GO:0009261 405 0.031
regulation of transferase activity GO:0051338 355 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.031
nucleotide catabolic process GO:0009166 408 0.031
regeneration GO:0031099 4 0.030
gtp metabolic process GO:0046039 239 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.029
negative regulation of cell death GO:0060548 345 0.029
system process GO:0003008 349 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
signal transduction by phosphorylation GO:0023014 297 0.028
positive regulation of nucleotide metabolic process GO:0045981 230 0.028
regulation of cellular component movement GO:0051270 334 0.028
regulation of small gtpase mediated signal transduction GO:0051056 156 0.028
positive regulation of cell proliferation GO:0008284 301 0.028
regulation of cell motility GO:2000145 299 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
organophosphate catabolic process GO:0046434 430 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
blood circulation GO:0008015 113 0.027
maintenance of location GO:0051235 112 0.027
guanosine containing compound metabolic process GO:1901068 244 0.027
cell adhesion GO:0007155 325 0.027
regulation of cellular response to stress GO:0080135 244 0.027
anion transport GO:0006820 161 0.027
neuromuscular junction development GO:0007528 3 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.026
regulation of protein kinase activity GO:0045859 289 0.026
organonitrogen compound biosynthetic process GO:1901566 200 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
neuron differentiation GO:0030182 138 0.026
cellular lipid metabolic process GO:0044255 303 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.025
negative regulation of cellular amine metabolic process GO:0033239 3 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
purine nucleoside catabolic process GO:0006152 398 0.025
single organism membrane organization GO:0044802 268 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
nucleoside catabolic process GO:0009164 408 0.025
protein localization to organelle GO:0033365 280 0.025
cell development GO:0048468 328 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.024
regulation of cell differentiation GO:0045595 393 0.024
response to abiotic stimulus GO:0009628 336 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.024
immune response GO:0006955 307 0.024
memory GO:0007613 3 0.024
guanosine containing compound catabolic process GO:1901069 239 0.023
glycoprotein metabolic process GO:0009100 110 0.023
rho protein signal transduction GO:0007266 26 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
regulation of mapk cascade GO:0043408 262 0.023
lipid biosynthetic process GO:0008610 177 0.023
mapk cascade GO:0000165 288 0.023
dephosphorylation GO:0016311 209 0.023
vacuole organization GO:0007033 44 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
chemical homeostasis GO:0048878 306 0.022
regulation of endopeptidase activity GO:0052548 170 0.022
striated muscle contraction GO:0006941 52 0.022
segmentation GO:0035282 4 0.022
vesicle mediated transport GO:0016192 371 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
ion homeostasis GO:0050801 230 0.021
positive regulation of transport GO:0051050 336 0.021
cell morphogenesis GO:0000902 296 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
positive regulation of catabolic process GO:0009896 310 0.021
purine containing compound catabolic process GO:0072523 411 0.021
chromatin modification GO:0016568 298 0.021
mitotic cell cycle GO:0000278 326 0.021
proteasomal protein catabolic process GO:0010498 176 0.020
response to oxygen containing compound GO:1901700 369 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
rhythmic behavior GO:0007622 2 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
cation transport GO:0006812 331 0.020
hindbrain development GO:0030902 3 0.020
positive regulation of transferase activity GO:0051347 227 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
positive regulation of kinase activity GO:0033674 204 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.020
muscle cell cellular homeostasis GO:0046716 3 0.020
defense response GO:0006952 315 0.020
anatomical structure homeostasis GO:0060249 100 0.020
cellular component morphogenesis GO:0032989 314 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
transmembrane transport GO:0055085 399 0.020
regulation of establishment of protein localization GO:0070201 242 0.019
positive regulation of ras gtpase activity GO:0032320 117 0.019
peripheral nervous system development GO:0007422 2 0.019
cellular protein catabolic process GO:0044257 261 0.019
protein processing GO:0016485 226 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
actin cytoskeleton organization GO:0030036 207 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
circadian behavior GO:0048512 2 0.019
regulation of ras protein signal transduction GO:0046578 155 0.019
apoptotic signaling pathway GO:0097190 268 0.019
blastoderm segmentation GO:0007350 2 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
positive regulation of immune system process GO:0002684 283 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
generation of neurons GO:0048699 152 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.018
microtubule based process GO:0007017 210 0.018
secretion GO:0046903 254 0.018
regulation of anatomical structure morphogenesis GO:0022603 286 0.018
regulation of locomotion GO:0040012 329 0.018
cellular protein complex assembly GO:0043623 188 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
regulation of cell cycle GO:0051726 393 0.018
g protein coupled receptor signaling pathway GO:0007186 207 0.018
oogenesis GO:0048477 2 0.018
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of secretion GO:0051046 194 0.018
biological adhesion GO:0022610 331 0.018
central nervous system development GO:0007417 123 0.018
regulation of gtpase activity GO:0043087 180 0.018
regulation of ras gtpase activity GO:0032318 128 0.017
cation homeostasis GO:0055080 189 0.017
purine nucleoside triphosphate catabolic process GO:0009146 392 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
epithelium development GO:0060429 227 0.017
alcohol metabolic process GO:0006066 114 0.017
protein localization to membrane GO:0072657 160 0.017
single organism cellular localization GO:1902580 332 0.017
regulation of protein localization GO:0032880 296 0.017
positive regulation of epithelial cell proliferation GO:0050679 65 0.017
cell growth GO:0016049 160 0.016
regulation of cell cycle process GO:0010564 266 0.016
circulatory system process GO:0003013 113 0.016
protein maturation GO:0051604 233 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
cellular cation homeostasis GO:0030003 163 0.016
norepinephrine transport GO:0015874 1 0.016
membrane organization GO:0061024 292 0.016
positive regulation of locomotion GO:0040017 186 0.016
negative regulation of developmental process GO:0051093 247 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
neuron projection development GO:0031175 106 0.015
neurogenesis GO:0022008 169 0.015
phospholipid metabolic process GO:0006644 99 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
neuroblast proliferation GO:0007405 4 0.015
regulation of peptidase activity GO:0052547 180 0.015
sleep GO:0030431 2 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
mitotic cell cycle process GO:1903047 286 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
negative regulation of protein modification process GO:0031400 200 0.015
histone modification GO:0016570 251 0.015
protein ubiquitination GO:0016567 314 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
negative regulation of protein phosphorylation GO:0001933 140 0.015
response to radiation GO:0009314 151 0.015
gtp catabolic process GO:0006184 237 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
sensory perception GO:0007600 103 0.015
regulation of cell migration GO:0030334 289 0.015
salivary gland morphogenesis GO:0007435 4 0.015
glycerolipid metabolic process GO:0046486 107 0.015
metal ion transport GO:0030001 272 0.015
response to axon injury GO:0048678 1 0.015
generation of precursor metabolites and energy GO:0006091 68 0.015
small molecule biosynthetic process GO:0044283 157 0.015
covalent chromatin modification GO:0016569 254 0.015
spermatid differentiation GO:0048515 4 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
peptidyl tyrosine modification GO:0018212 170 0.014
cell projection morphogenesis GO:0048858 129 0.014
female gamete generation GO:0007292 2 0.014
cardiac muscle contraction GO:0060048 34 0.014
secretion by cell GO:0032940 226 0.014
metencephalon development GO:0022037 2 0.014
regulation of protein transport GO:0051223 213 0.014
positive regulation of cell motility GO:2000147 177 0.014
respiratory gaseous exchange GO:0007585 3 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
intracellular protein transport GO:0006886 270 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
negative regulation of organelle organization GO:0010639 126 0.014
regulation of secretion by cell GO:1903530 177 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
regulation of proteolysis GO:0030162 293 0.014
regulation of cell growth GO:0001558 135 0.014
cellular ion homeostasis GO:0006873 168 0.014
taxis GO:0042330 157 0.014
positive regulation of cytokine production GO:0001819 167 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
neuron development GO:0048666 113 0.014
regulation of system process GO:0044057 101 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
innate immune response GO:0045087 178 0.013
spermatid development GO:0007286 4 0.013
positive regulation of cell death GO:0010942 263 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
regulation of protein catabolic process GO:0042176 155 0.013
muscle system process GO:0003012 81 0.013
regulation of dna metabolic process GO:0051052 153 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
regulation of cell development GO:0060284 161 0.013
inorganic anion transport GO:0015698 60 0.013
monocarboxylic acid metabolic process GO:0032787 185 0.013
positive regulation of developmental process GO:0051094 314 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
maintenance of location in cell GO:0051651 62 0.013
negative regulation of locomotion GO:0040013 118 0.013
ossification GO:0001503 121 0.013
cell part morphogenesis GO:0032990 137 0.013
carboxylic acid catabolic process GO:0046395 71 0.013
negative regulation of cell migration GO:0030336 102 0.013
organic hydroxy compound transport GO:0015850 63 0.013
cell cycle phase transition GO:0044770 173 0.013
positive regulation of secretion GO:0051047 116 0.013
lymphocyte activation GO:0046649 133 0.013
positive regulation of cellular component movement GO:0051272 181 0.012
cell projection assembly GO:0030031 126 0.012
protein acylation GO:0043543 138 0.012
regulation of protein maturation GO:1903317 150 0.012
regulation of neuron differentiation GO:0045664 70 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
ion transmembrane transport GO:0034220 338 0.012
cellular response to abiotic stimulus GO:0071214 117 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
negative regulation of cell cycle GO:0045786 193 0.012
inner ear morphogenesis GO:0042472 4 0.012
regulation of response to external stimulus GO:0032101 222 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
cellular chemical homeostasis GO:0055082 180 0.012
regulation of growth GO:0040008 165 0.012
mitochondrion organization GO:0007005 156 0.012
regulation of blood vessel remodeling GO:0060312 2 0.012
cellular response to oxidative stress GO:0034599 85 0.012
response to oxidative stress GO:0006979 121 0.012
cerebellum development GO:0021549 2 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of cytokine production GO:0001817 232 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
prostate gland development GO:0030850 3 0.012
negative regulation of catabolic process GO:0009895 104 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
positive regulation of cell migration GO:0030335 172 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
blastocyst development GO:0001824 3 0.012
oocyte development GO:0048599 1 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
cell activation GO:0001775 213 0.012
chemotaxis GO:0006935 157 0.012
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.012
lipid localization GO:0010876 106 0.012
epithelial cell proliferation GO:0050673 128 0.012
cellular amide metabolic process GO:0043603 69 0.012
organelle assembly GO:0070925 176 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
response to fungus GO:0009620 4 0.012
protein autophosphorylation GO:0046777 123 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
response to cytokine GO:0034097 232 0.011
regulation of intracellular transport GO:0032386 195 0.011
head development GO:0060322 108 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
nuclear transport GO:0051169 179 0.011
sensory perception of pain GO:0019233 4 0.011
associative learning GO:0008306 1 0.011
oocyte differentiation GO:0009994 2 0.011
metal ion homeostasis GO:0055065 169 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
response to other organism GO:0051707 261 0.011
nitrogen compound transport GO:0071705 191 0.011
response to wounding GO:0009611 168 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
small molecule catabolic process GO:0044282 92 0.011
nerve development GO:0021675 4 0.011
cardiovascular system development GO:0072358 262 0.011
long term memory GO:0007616 2 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
brain development GO:0007420 97 0.011
somitogenesis GO:0001756 2 0.011
response to external biotic stimulus GO:0043207 261 0.011
lysosome organization GO:0007040 24 0.011
cell chemotaxis GO:0060326 112 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
protein oligomerization GO:0051259 173 0.011
growth GO:0040007 202 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
positive regulation of organelle organization GO:0010638 195 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
neural tube formation GO:0001841 3 0.011
cellular polysaccharide metabolic process GO:0044264 27 0.011
organ morphogenesis GO:0009887 147 0.011
respiratory system process GO:0003016 3 0.011
cellular response to reactive oxygen species GO:0034614 50 0.011
skeletal muscle contraction GO:0003009 16 0.011
chromatin organization GO:0006325 351 0.011
regulation of nervous system development GO:0051960 88 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
rna processing GO:0006396 255 0.011
protein dephosphorylation GO:0006470 81 0.011
regulation of protein processing GO:0070613 150 0.011
negative regulation of transferase activity GO:0051348 124 0.011
sex determination GO:0007530 3 0.011
response to lipid GO:0033993 206 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
tube closure GO:0060606 3 0.011
regulation of immune response GO:0050776 201 0.011
anterior posterior axis specification GO:0009948 2 0.011
polysaccharide metabolic process GO:0005976 33 0.011
dna repair GO:0006281 198 0.011
glycogen catabolic process GO:0005980 4 0.011
lipid transport GO:0006869 90 0.011
mammary gland morphogenesis GO:0060443 2 0.011
regulation of defense response GO:0031347 154 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
organelle localization GO:0051640 84 0.011
lytic vacuole organization GO:0080171 24 0.011
positive regulation of synaptic transmission GO:0050806 4 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.010
positive regulation of protein transport GO:0051222 135 0.010
monosaccharide metabolic process GO:0005996 74 0.010
lung alveolus development GO:0048286 4 0.010
protein targeting GO:0006605 187 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
sulfur compound metabolic process GO:0006790 101 0.010
endochondral bone morphogenesis GO:0060350 3 0.010
cell substrate adhesion GO:0031589 132 0.010
mucopolysaccharide metabolic process GO:1903510 27 0.010
mitotic nuclear division GO:0007067 119 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
organelle fission GO:0048285 149 0.010
stem cell division GO:0017145 2 0.010
peptidyl lysine modification GO:0018205 144 0.010
cation transmembrane transport GO:0098655 238 0.010
epithelial cell differentiation GO:0030855 141 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
adult locomotory behavior GO:0008344 1 0.010
heart process GO:0003015 62 0.010
negative regulation of neurological system process GO:0031645 2 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
response to growth factor GO:0070848 205 0.010
endocytosis GO:0006897 159 0.010

SGSH disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.276
inherited metabolic disorder DOID:655 242 0.201
glycogen storage disease DOID:2747 10 0.041
carbohydrate metabolic disorder DOID:2978 55 0.041
glycogen metabolism disorder DOID:0050728 10 0.041
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035
lysosomal storage disease DOID:3211 47 0.031
musculoskeletal system disease DOID:17 223 0.027
sensory system disease DOID:0050155 203 0.026
neurodegenerative disease DOID:1289 102 0.024
lipid storage disease DOID:9455 28 0.023
eye and adnexa disease DOID:1492 150 0.022
eye disease DOID:5614 149 0.022
bone disease DOID:0080001 88 0.017
connective tissue disease DOID:65 109 0.017
muscular disease DOID:0080000 114 0.017
muscle tissue disease DOID:66 113 0.017
retinal disease DOID:5679 118 0.015
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.013
myopathy DOID:423 104 0.013
retinal degeneration DOID:8466 89 0.012
kidney disease DOID:557 36 0.012
urinary system disease DOID:18 40 0.012
disease of mental health DOID:150 70 0.012
acquired metabolic disease DOID:0060158 58 0.010
mucopolysaccharidosis DOID:12798 11 0.004
mucopolysaccharidosis iii DOID:12801 4 0.001