Homo sapiens

63 known processes

MSH3

mutS homolog 3 (E. coli)

(Aliases: DUP,MGC163308,MRP1,MGC163306)

MSH3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide excision repair GO:0006289 31 0.779
dna repair GO:0006281 198 0.714
mismatch repair GO:0006298 15 0.707
cellular response to dna damage stimulus GO:0006974 379 0.691
double strand break repair GO:0006302 101 0.560
isotype switching GO:0045190 3 0.503
dna recombination GO:0006310 77 0.407
sex determination GO:0007530 3 0.394
Yeast
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.342
Mouse
dna damage checkpoint GO:0000077 68 0.327
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.305
somatic diversification of immune receptors via somatic mutation GO:0002566 1 0.296
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.256
Yeast
telomere maintenance GO:0000723 32 0.239
purine nucleoside catabolic process GO:0006152 398 0.199
Yeast
anatomical structure homeostasis GO:0060249 100 0.199
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.193
Yeast
positive regulation of hydrolase activity GO:0051345 331 0.190
cellular macromolecule catabolic process GO:0044265 380 0.189
Yeast
lymphocyte mediated immunity GO:0002449 48 0.182
double strand break repair via homologous recombination GO:0000724 50 0.175
purine ribonucleoside catabolic process GO:0046130 398 0.173
Yeast
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.165
meiosis i GO:0007127 4 0.157
Yeast
apoptotic signaling pathway GO:0097190 268 0.155
ribonucleotide catabolic process GO:0009261 405 0.149
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 392 0.147
Yeast
purine nucleotide catabolic process GO:0006195 405 0.146
Yeast
response to abiotic stimulus GO:0009628 336 0.140
response to radiation GO:0009314 151 0.139
purine nucleoside triphosphate metabolic process GO:0009144 412 0.138
Yeast
immune response GO:0006955 307 0.138
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.137
dna double strand break processing GO:0000729 10 0.133
glycosyl compound catabolic process GO:1901658 413 0.132
Yeast
interstrand cross link repair GO:0036297 3 0.127
purine nucleoside monophosphate catabolic process GO:0009128 158 0.122
Yeast
intrinsic apoptotic signaling pathway GO:0097193 127 0.121
nucleoside catabolic process GO:0009164 408 0.120
Yeast
regulation of dna recombination GO:0000018 23 0.120
nucleoside phosphate catabolic process GO:1901292 412 0.110
Yeast
negative regulation of cell cycle GO:0045786 193 0.109
purine ribonucleotide catabolic process GO:0009154 404 0.108
Yeast
cell development GO:0048468 328 0.108
purine containing compound catabolic process GO:0072523 411 0.107
Yeast
somatic hypermutation of immunoglobulin genes GO:0016446 1 0.106
nucleoside monophosphate metabolic process GO:0009123 191 0.103
Yeast
dna replication GO:0006260 116 0.102
multicellular organismal aging GO:0010259 3 0.101
ribonucleoside monophosphate metabolic process GO:0009161 187 0.097
Yeast
response to ionizing radiation GO:0010212 65 0.096
determination of adult lifespan GO:0008340 2 0.094
dna integrity checkpoint GO:0031570 71 0.094
recombinational repair GO:0000725 50 0.093
immune system development GO:0002520 195 0.089
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.089
Yeast
negative regulation of mitotic cell cycle GO:0045930 102 0.086
double strand break repair via single strand annealing GO:0045002 4 0.086
regulation of dna metabolic process GO:0051052 153 0.085
regulation of cell cycle GO:0051726 393 0.085
somatic diversification of immunoglobulins GO:0016445 6 0.082
Mouse
regulation of meiotic cell cycle GO:0051445 4 0.080
b cell activation GO:0042113 33 0.077
telomere maintenance via telomerase GO:0007004 8 0.076
negative regulation of cell cycle phase transition GO:1901988 89 0.075
leukocyte mediated immunity GO:0002443 59 0.075
nucleoside triphosphate metabolic process GO:0009141 422 0.074
Yeast
leukocyte activation GO:0045321 164 0.073
ribonucleoside triphosphate catabolic process GO:0009203 391 0.073
Yeast
nucleotide catabolic process GO:0009166 408 0.072
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.071
Yeast
ribonucleoside catabolic process GO:0042454 406 0.071
Yeast
adaptive immune response GO:0002250 49 0.069
intra s dna damage checkpoint GO:0031573 4 0.068
rna processing GO:0006396 255 0.068
regulation of cell cycle phase transition GO:1901987 126 0.068
meiotic chromosome segregation GO:0045132 4 0.067
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.065
Yeast
response to uv GO:0009411 73 0.064
dna catabolic process GO:0006308 49 0.064
Yeast
immune effector process GO:0002252 159 0.063
regulation of cell division GO:0051302 116 0.062
atp metabolic process GO:0046034 176 0.061
Yeast
midbrain development GO:0030901 45 0.060
cell cycle checkpoint GO:0000075 117 0.056
ribonucleoside triphosphate metabolic process GO:0009199 412 0.053
Yeast
negative regulation of cell cycle process GO:0010948 121 0.052
negative regulation of programmed cell death GO:0043069 321 0.051
cellular protein complex assembly GO:0043623 188 0.050
regulation of meiosis GO:0040020 3 0.049
telomere maintenance via telomere lengthening GO:0010833 9 0.048
maintenance of dna repeat elements GO:0043570 4 0.048
ribonucleoside monophosphate catabolic process GO:0009158 158 0.048
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.047
Yeast
nucleoside monophosphate catabolic process GO:0009125 159 0.047
Yeast
cell morphogenesis GO:0000902 296 0.047
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.047
cellular response to abiotic stimulus GO:0071214 117 0.047
purine nucleoside monophosphate metabolic process GO:0009126 186 0.046
Yeast
regulation of cell cycle process GO:0010564 266 0.046
negative regulation of cell death GO:0060548 345 0.044
compound eye development GO:0048749 1 0.044
somatic diversification of immune receptors GO:0002200 8 0.043
Mouse
negative regulation of dna recombination GO:0045910 6 0.042
atp catabolic process GO:0006200 157 0.042
Yeast
nuclear division GO:0000280 128 0.042
Yeast
cellular ketone metabolic process GO:0042180 80 0.042
cellular amino acid metabolic process GO:0006520 116 0.041
cell cycle arrest GO:0007050 71 0.040
mitotic cell cycle phase transition GO:0044772 162 0.039
female gamete generation GO:0007292 2 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.037
Yeast
ion homeostasis GO:0050801 230 0.037
protein polyubiquitination GO:0000209 110 0.037
postreplication repair GO:0006301 12 0.036
mitotic cell cycle GO:0000278 326 0.036
cardiovascular system development GO:0072358 262 0.036
positive regulation of helicase activity GO:0051096 6 0.036
organelle fission GO:0048285 149 0.036
Yeast
negative regulation of catalytic activity GO:0043086 335 0.033
microtubule based process GO:0007017 210 0.033
lymphocyte activation GO:0046649 133 0.033
telomere maintenance via recombination GO:0000722 4 0.033
protein processing GO:0016485 226 0.033
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
cell activation involved in immune response GO:0002263 30 0.032
chromosome segregation GO:0007059 114 0.031
cell division GO:0051301 168 0.031
gene conversion GO:0035822 1 0.031
Yeast
lymphocyte activation involved in immune response GO:0002285 20 0.030
regeneration GO:0031099 4 0.030
leukocyte differentiation GO:0002521 98 0.029
dna catabolic process exonucleolytic GO:0000738 17 0.029
post embryonic development GO:0009791 2 0.029
oogenesis GO:0048477 2 0.029
amine metabolic process GO:0009308 44 0.029
g2 dna damage checkpoint GO:0031572 26 0.029
protein ubiquitination GO:0016567 314 0.029
leukocyte activation involved in immune response GO:0002366 30 0.029
covalent chromatin modification GO:0016569 254 0.028
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.028
hindbrain development GO:0030902 3 0.027
positive regulation of transport GO:0051050 336 0.027
response to oxygen containing compound GO:1901700 369 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
response to light stimulus GO:0009416 87 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
production of molecular mediator of immune response GO:0002440 37 0.027
Mouse
reciprocal meiotic recombination GO:0007131 4 0.027
segmentation GO:0035282 4 0.027
mitotic dna damage checkpoint GO:0044773 28 0.026
regulation of helicase activity GO:0051095 8 0.026
blastoderm segmentation GO:0007350 2 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.026
signal transduction by phosphorylation GO:0023014 297 0.026
cell projection organization GO:0030030 252 0.026
cellular response to external stimulus GO:0071496 111 0.026
central nervous system development GO:0007417 123 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
chemical homeostasis GO:0048878 306 0.026
meiotic nuclear division GO:0007126 10 0.026
Yeast
cellular homeostasis GO:0019725 196 0.025
circulatory system development GO:0072359 262 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
signal transduction by p53 class mediator GO:0072331 72 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.024
organophosphate catabolic process GO:0046434 430 0.024
Yeast
cytoplasmic transport GO:0016482 379 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
hemopoiesis GO:0030097 180 0.024
blood vessel development GO:0001568 172 0.024
meiotic gene conversion GO:0006311 1 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
negative regulation of meiotic cell cycle GO:0051447 2 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
response to nitrogen compound GO:1901698 184 0.023
regulation of multi organism process GO:0043900 157 0.023
cell activation GO:0001775 213 0.023
ras protein signal transduction GO:0007265 73 0.023
negative regulation of organelle organization GO:0010639 126 0.023
neural nucleus development GO:0048857 47 0.023
angiogenesis GO:0001525 147 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
substantia nigra development GO:0021762 45 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
response to organic cyclic compound GO:0014070 204 0.022
anatomical structure formation involved in morphogenesis GO:0048646 284 0.022
metal ion homeostasis GO:0055065 169 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
immunoglobulin mediated immune response GO:0016064 10 0.021
regulation of cellular component biogenesis GO:0044087 281 0.021
cell type specific apoptotic process GO:0097285 125 0.021
protein maturation GO:0051604 233 0.021
b cell mediated immunity GO:0019724 10 0.020
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.020
innate immune response GO:0045087 178 0.020
mrna processing GO:0006397 133 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
protein catabolic process GO:0030163 325 0.020
regulation of transferase activity GO:0051338 355 0.020
generation of precursor metabolites and energy GO:0006091 68 0.020
tripartite regional subdivision GO:0007351 2 0.020
protein autophosphorylation GO:0046777 123 0.020
actin filament based process GO:0030029 224 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
development of primary male sexual characteristics GO:0046546 23 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
meiotic cell cycle GO:0051321 13 0.019
Yeast
positive regulation of programmed cell death GO:0043068 249 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
calcium ion homeostasis GO:0055074 122 0.019
telomere organization GO:0032200 33 0.019
response to lipid GO:0033993 206 0.019
vasculature development GO:0001944 181 0.019
regulation of cellular component movement GO:0051270 334 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
regulation of protein transport GO:0051223 213 0.018
regulation of kinase activity GO:0043549 314 0.018
positive regulation of cell death GO:0010942 263 0.018
blastocyst development GO:0001824 3 0.018
cellular metal ion homeostasis GO:0006875 146 0.018
dna catabolic process endonucleolytic GO:0000737 37 0.018
Yeast
response to inorganic substance GO:0010035 127 0.018
regulation of vasculature development GO:1901342 97 0.018
positive regulation of kinase activity GO:0033674 204 0.018
regulation of cell differentiation GO:0045595 393 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
cellular component morphogenesis GO:0032989 314 0.018
positive regulation of protein transport GO:0051222 135 0.018
anterior posterior axis specification embryo GO:0008595 2 0.017
regulation of locomotion GO:0040012 329 0.017
regulation of dna replication GO:0006275 68 0.017
regulation of cell migration GO:0030334 289 0.017
response to biotic stimulus GO:0009607 276 0.017
system process GO:0003008 349 0.017
regulation of angiogenesis GO:0045765 92 0.017
regulation of cell motility GO:2000145 299 0.017
cation homeostasis GO:0055080 189 0.017
actin filament organization GO:0007015 128 0.017
tissue regeneration GO:0042246 3 0.017
nervous system development GO:0007399 293 0.017
epithelial cell differentiation GO:0030855 141 0.017
neuromuscular junction development GO:0007528 3 0.017
positive regulation of response to dna damage stimulus GO:2001022 43 0.017
response to uv b GO:0010224 10 0.017
male gonad development GO:0008584 23 0.017
cellular ion homeostasis GO:0006873 168 0.017
single organism cellular localization GO:1902580 332 0.017
dephosphorylation GO:0016311 209 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.016
cell part morphogenesis GO:0032990 137 0.016
regulation of protein localization GO:0032880 296 0.016
regulation of protein binding GO:0043393 66 0.016
intracellular mrna localization GO:0008298 1 0.016
tube morphogenesis GO:0035239 95 0.016
cellular amine metabolic process GO:0044106 41 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
oocyte development GO:0048599 1 0.016
generation of neurons GO:0048699 152 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
cellular chemical homeostasis GO:0055082 180 0.016
response to organonitrogen compound GO:0010243 156 0.016
positive regulation of cell differentiation GO:0045597 211 0.016
cellular cation homeostasis GO:0030003 163 0.016
non recombinational repair GO:0000726 14 0.016
metencephalon development GO:0022037 2 0.016
response to caffeine GO:0031000 3 0.016
positive regulation of transferase activity GO:0051347 227 0.015
regulation of cytokine production GO:0001817 232 0.015
positive regulation of cytokine production GO:0001819 167 0.015
somitogenesis GO:0001756 2 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
intracellular protein transport GO:0006886 270 0.015
epithelium development GO:0060429 227 0.015
negative regulation of blood vessel morphogenesis GO:2000181 41 0.015
cellular protein catabolic process GO:0044257 261 0.015
actin cytoskeleton organization GO:0030036 207 0.015
regulation of cell development GO:0060284 161 0.015
cell projection assembly GO:0030031 126 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
negative regulation of developmental process GO:0051093 247 0.015
multi organism cellular process GO:0044764 156 0.015
negative regulation of dna metabolic process GO:0051053 57 0.015
negative regulation of vasculature development GO:1901343 43 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
positive regulation of developmental process GO:0051094 314 0.015
response to wounding GO:0009611 168 0.015
oocyte differentiation GO:0009994 2 0.015
brain development GO:0007420 97 0.015
mrna metabolic process GO:0016071 175 0.015
regulation of proteolysis GO:0030162 293 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
translesion synthesis GO:0019985 8 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
anterior posterior axis specification GO:0009948 2 0.014
cellular response to ionizing radiation GO:0071479 32 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
transmembrane transport GO:0055085 399 0.014
regulation of immune response GO:0050776 201 0.014
defense response GO:0006952 315 0.014
neural tube closure GO:0001843 3 0.014
protein oligomerization GO:0051259 173 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
negative regulation of angiogenesis GO:0016525 39 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
nuclear transport GO:0051169 179 0.014
neuron apoptotic process GO:0051402 39 0.014
regulation of neuron death GO:1901214 56 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
mapk cascade GO:0000165 288 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of epithelial cell proliferation GO:0050678 113 0.014
cell adhesion GO:0007155 325 0.014
chromatin modification GO:0016568 298 0.014
retinal ganglion cell axon guidance GO:0031290 2 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.013
meiotic chromosome separation GO:0051307 3 0.013
spermatid development GO:0007286 4 0.013
reproduction GO:0000003 63 0.013
Yeast
associative learning GO:0008306 1 0.013
regulation of protein kinase activity GO:0045859 289 0.013
histone modification GO:0016570 251 0.013
epithelial cell proliferation GO:0050673 128 0.013
regulation of cellular response to stress GO:0080135 244 0.013
lipid metabolic process GO:0006629 381 0.013
regulation of carbohydrate metabolic process GO:0006109 54 0.013
response to hormone GO:0009725 175 0.013
membrane organization GO:0061024 292 0.013
male sex differentiation GO:0046661 25 0.013
neuron death GO:0070997 65 0.013
memory GO:0007613 3 0.013
chromatin organization GO:0006325 351 0.013
single organism membrane organization GO:0044802 268 0.013
immunoglobulin production GO:0002377 12 0.013
Mouse
base excision repair GO:0006284 21 0.013
regulation of growth GO:0040008 165 0.013
small molecule biosynthetic process GO:0044283 157 0.013
cytokine production GO:0001816 247 0.013
primary neural tube formation GO:0014020 3 0.012
biological adhesion GO:0022610 331 0.012
regulation of homeostatic process GO:0032844 121 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
protein localization to membrane GO:0072657 160 0.012
positive regulation of organelle organization GO:0010638 195 0.012
aging GO:0007568 66 0.012
reproductive process GO:0022414 106 0.012
Yeast
long chain fatty acid metabolic process GO:0001676 30 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
rna splicing GO:0008380 131 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
tissue morphogenesis GO:0048729 96 0.012
head development GO:0060322 108 0.012
organ morphogenesis GO:0009887 147 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
somatic cell dna recombination GO:0016444 6 0.012
Mouse
negative regulation of hydrolase activity GO:0051346 182 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
negative regulation of transport GO:0051051 176 0.012
regulation of protein catabolic process GO:0042176 155 0.012
ion transmembrane transport GO:0034220 338 0.012
positive regulation of catabolic process GO:0009896 310 0.011
sulfur compound metabolic process GO:0006790 101 0.011
mitotic recombination GO:0006312 8 0.011
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
protein polymerization GO:0051258 71 0.011
cellular response to radiation GO:0071478 65 0.011
neural tube formation GO:0001841 3 0.011
reciprocal dna recombination GO:0035825 4 0.011
protein localization to organelle GO:0033365 280 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
response to metal ion GO:0010038 84 0.011
tube closure GO:0060606 3 0.011
maintenance of location GO:0051235 112 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
metal ion transport GO:0030001 272 0.011
viral process GO:0016032 146 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
regulation of peptidase activity GO:0052547 180 0.011
response to growth factor GO:0070848 205 0.011
regulation of dephosphorylation GO:0035303 96 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
detection of stimulus GO:0051606 85 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
regulation of double strand break repair via homologous recombination GO:0010569 11 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
response to axon injury GO:0048678 1 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
interspecies interaction between organisms GO:0044419 156 0.010
regulation of endothelial cell differentiation GO:0045601 4 0.010
growth GO:0040007 202 0.010
humoral immune response GO:0006959 49 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of rna splicing GO:0043484 62 0.010
cellular lipid metabolic process GO:0044255 303 0.010
cell fate commitment GO:0045165 27 0.010
Yeast
response to cytokine GO:0034097 232 0.010
negative regulation of cell differentiation GO:0045596 171 0.010
negative regulation of transferase activity GO:0051348 124 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
dna duplex unwinding GO:0032508 30 0.010
negative regulation of dna replication GO:0008156 29 0.010
regulation of endothelial cell proliferation GO:0001936 56 0.010
response to other organism GO:0051707 261 0.010
cellular response to lipid GO:0071396 127 0.010
rhythmic behavior GO:0007622 2 0.010
positive regulation of cell development GO:0010720 92 0.010
negative regulation of cell migration GO:0030336 102 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
endothelial cell proliferation GO:0001935 65 0.010

MSH3 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.123
disease of cellular proliferation DOID:14566 174 0.116
cancer DOID:162 167 0.104
organ system cancer DOID:0050686 164 0.049
reproductive organ cancer DOID:193 23 0.040
female reproductive organ cancer DOID:120 10 0.040
disease of metabolism DOID:0014667 295 0.032
hematopoietic system disease DOID:74 100 0.030
anemia DOID:2355 55 0.028
sensory system disease DOID:0050155 203 0.018
nervous system disease DOID:863 431 0.018
musculoskeletal system disease DOID:17 223 0.017
eye and adnexa disease DOID:1492 150 0.017
endocrine gland cancer DOID:170 26 0.014
retinal disease DOID:5679 118 0.014
eye disease DOID:5614 149 0.014
inherited metabolic disorder DOID:655 242 0.013