Homo sapiens

0 known processes

PSMB9

proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)

(Aliases: PSMB6i,MGC70470,RING12,beta1i,LMP2)

PSMB9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
multi organism cellular process GO:0044764 156 0.937
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.899
viral process GO:0016032 146 0.887
response to other organism GO:0051707 261 0.881
antigen processing and presentation GO:0019882 33 0.850
positive regulation of immune system process GO:0002684 283 0.819
immune effector process GO:0002252 159 0.729
viral life cycle GO:0019058 132 0.714
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.680
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.628
multi organism intracellular transport GO:1902583 14 0.612
t cell activation GO:0042110 99 0.610
regulation of viral entry into host cell GO:0046596 17 0.495
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.443
cellular macromolecule catabolic process GO:0044265 380 0.438
cellular protein catabolic process GO:0044257 261 0.425
regulation of apoptotic signaling pathway GO:2001233 175 0.368
modification dependent protein catabolic process GO:0019941 209 0.358
negative regulation of intracellular transport of viral material GO:1901253 2 0.357
multi organism localization GO:1902579 14 0.299
isg15 protein conjugation GO:0032020 5 0.282
regulation of innate immune response GO:0045088 97 0.279
response to virus GO:0009615 126 0.269
defense response to other organism GO:0098542 129 0.263
mononuclear cell proliferation GO:0032943 71 0.256
proteasomal protein catabolic process GO:0010498 176 0.244
regulation of immune response GO:0050776 201 0.238
interspecies interaction between organisms GO:0044419 156 0.216
antigen processing and presentation of exogenous antigen GO:0019884 4 0.215
positive regulation of immune response GO:0050778 159 0.213
response to external biotic stimulus GO:0043207 261 0.182
positive regulation of proteolysis GO:0045862 142 0.178
ubiquitin dependent protein catabolic process GO:0006511 206 0.178
cellular response to cytokine stimulus GO:0071345 181 0.177
modification dependent macromolecule catabolic process GO:0043632 212 0.176
positive regulation of leukocyte activation GO:0002696 80 0.171
regulation of lymphocyte activation GO:0051249 103 0.165
defense response GO:0006952 315 0.164
protein catabolic process GO:0030163 325 0.163
defense response to virus GO:0051607 71 0.161
negative regulation of multi organism process GO:0043901 92 0.158
immune response GO:0006955 307 0.157
regulation of t cell proliferation GO:0042129 42 0.151
innate immune response GO:0045087 178 0.150
cytoplasmic transport GO:0016482 379 0.144
t cell proliferation GO:0042098 45 0.140
mitotic cell cycle process GO:1903047 286 0.127
apoptotic signaling pathway GO:0097190 268 0.125
determination of adult lifespan GO:0008340 2 0.124
regulation of leukocyte activation GO:0002694 115 0.122
regulation of endopeptidase activity GO:0052548 170 0.119
leukocyte activation GO:0045321 164 0.118
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.114
regulation of interferon gamma production GO:0032649 36 0.111
positive regulation of cytokine production GO:0001819 167 0.108
intracellular protein transport GO:0006886 270 0.105
negative regulation of programmed cell death GO:0043069 321 0.104
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 2 0.103
nucleoside triphosphate catabolic process GO:0009143 394 0.098
regulation of transferase activity GO:0051338 355 0.098
leukocyte mediated immunity GO:0002443 59 0.097
leukocyte proliferation GO:0070661 74 0.096
antigen processing and presentation of peptide antigen GO:0048002 18 0.095
natural killer cell mediated immunity GO:0002228 23 0.094
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.093
regulation of multi organism process GO:0043900 157 0.087
ribonucleoside catabolic process GO:0042454 406 0.087
positive regulation of t cell activation GO:0050870 54 0.082
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.080
purine nucleoside triphosphate catabolic process GO:0009146 392 0.077
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.076
regulation of proteolysis GO:0030162 293 0.074
positive regulation of cell death GO:0010942 263 0.073
post embryonic development GO:0009791 2 0.072
purine nucleotide catabolic process GO:0006195 405 0.070
positive regulation of secretion GO:0051047 116 0.067
purine nucleoside catabolic process GO:0006152 398 0.067
activation of innate immune response GO:0002218 55 0.067
transport of virus GO:0046794 14 0.066
response to biotic stimulus GO:0009607 276 0.065
cellular response to dna damage stimulus GO:0006974 379 0.064
negative regulation of immune response GO:0050777 40 0.064
multi organism transport GO:0044766 14 0.062
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.061
negative regulation of viral process GO:0048525 66 0.058
purine ribonucleotide catabolic process GO:0009154 404 0.058
positive regulation of developmental process GO:0051094 314 0.057
regulation of cellular protein catabolic process GO:1903362 96 0.056
lymphocyte mediated immunity GO:0002449 48 0.056
extrinsic apoptotic signaling pathway GO:0097191 119 0.054
cellular macromolecular complex assembly GO:0034622 324 0.053
positive regulation of interleukin 13 production GO:0032736 4 0.053
response to bacterium GO:0009617 144 0.052
positive regulation of lymphocyte activation GO:0051251 73 0.050
organophosphate catabolic process GO:0046434 430 0.049
regulation of cell activation GO:0050865 125 0.049
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 6 0.048
microtubule organizing center organization GO:0031023 62 0.047
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.047
regulation of viral process GO:0050792 103 0.047
positive regulation of peptidase activity GO:0010952 88 0.047
chemical homeostasis GO:0048878 306 0.046
positive regulation of hydrolase activity GO:0051345 331 0.044
regulation of secretion by cell GO:1903530 177 0.042
mitotic cell cycle GO:0000278 326 0.041
cellular protein complex assembly GO:0043623 188 0.041
nucleotide catabolic process GO:0009166 408 0.041
centrosome organization GO:0051297 58 0.041
regulation of establishment of protein localization GO:0070201 242 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
nervous system development GO:0007399 293 0.039
regulation of interleukin 1 beta secretion GO:0050706 12 0.039
regulation of leukocyte differentiation GO:1902105 61 0.039
regulation by virus of viral protein levels in host cell GO:0046719 4 0.038
regulation of secretion GO:0051046 194 0.038
regulation of cell differentiation GO:0045595 393 0.038
negative regulation of cell motility GO:2000146 104 0.037
leukocyte differentiation GO:0002521 98 0.037
regulation of adaptive immune response GO:0002819 33 0.037
purine containing compound catabolic process GO:0072523 411 0.037
mitotic spindle elongation GO:0000022 4 0.036
entry into host GO:0044409 25 0.035
glycosyl compound catabolic process GO:1901658 413 0.035
positive regulation of cell differentiation GO:0045597 211 0.034
cell activation GO:0001775 213 0.034
cell cycle phase transition GO:0044770 173 0.034
regulation of peptidase activity GO:0052547 180 0.033
adaptive immune response GO:0002250 49 0.033
muscle structure development GO:0061061 98 0.033
regulation of cellular component movement GO:0051270 334 0.032
regulation of cytoskeleton organization GO:0051493 177 0.032
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 2 0.032
purine ribonucleoside catabolic process GO:0046130 398 0.031
negative regulation of catalytic activity GO:0043086 335 0.030
interferon gamma production GO:0032609 39 0.030
leukocyte mediated cytotoxicity GO:0001909 27 0.030
positive regulation of leukocyte proliferation GO:0070665 48 0.030
lymphocyte proliferation GO:0046651 70 0.030
negative regulation of apoptotic signaling pathway GO:2001234 97 0.029
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.029
secretion GO:0046903 254 0.029
membrane hyperpolarization GO:0060081 1 0.028
natural killer cell mediated cytotoxicity GO:0042267 23 0.028
spindle elongation GO:0051231 4 0.028
interaction with host GO:0051701 42 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
regulation of immune effector process GO:0002697 91 0.027
lymphocyte activation GO:0046649 133 0.026
immune response activating signal transduction GO:0002757 90 0.026
regulation of actin filament based process GO:0032970 141 0.026
negative regulation of viral transcription GO:0032897 23 0.026
positive regulation of endopeptidase activity GO:0010950 84 0.026
regulation of leukocyte proliferation GO:0070663 67 0.025
negative regulation of cell migration GO:0030336 102 0.025
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.025
regulation of defense response GO:0031347 154 0.024
negative regulation of leukocyte activation GO:0002695 26 0.024
multi organism metabolic process GO:0044033 41 0.024
positive regulation of leukocyte mediated immunity GO:0002705 24 0.024
positive regulation of interleukin 4 production GO:0032753 3 0.024
positive regulation of apoptotic process GO:0043065 246 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
melanin metabolic process GO:0006582 1 0.023
protein oligomerization GO:0051259 173 0.022
amide transport GO:0042886 76 0.022
viral genome replication GO:0019079 50 0.022
cation transport GO:0006812 331 0.022
positive regulation of cell activation GO:0050867 81 0.022
regulation of mononuclear cell proliferation GO:0032944 65 0.022
positive regulation of adaptive immune response GO:0002821 21 0.022
response to molecule of bacterial origin GO:0002237 82 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.021
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.021
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
system process GO:0003008 349 0.021
regulation of protein catabolic process GO:0042176 155 0.021
cytokine production GO:0001816 247 0.021
multicellular organismal aging GO:0010259 3 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.020
regulation of cell migration GO:0030334 289 0.020
interleukin 4 biosynthetic process GO:0042097 2 0.020
regulation of cell motility GO:2000145 299 0.020
sensory perception of bitter taste GO:0050913 28 0.020
positive regulation of protein ubiquitination GO:0031398 53 0.019
secretion by cell GO:0032940 226 0.019
viral transcription GO:0019083 35 0.019
regulation of ligase activity GO:0051340 29 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
viral gene expression GO:0019080 35 0.019
activation of cysteine type endopeptidase activity GO:0097202 57 0.019
cellular response to external stimulus GO:0071496 111 0.018
positive regulation of antigen processing and presentation GO:0002579 1 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
negative regulation of cell death GO:0060548 345 0.018
molting cycle GO:0042303 28 0.018
cell cell signaling GO:0007267 155 0.018
negative regulation of locomotion GO:0040013 118 0.018
regulation of t cell activation GO:0050863 77 0.018
regulation of protein transport GO:0051223 213 0.018
regulation of t cell differentiation GO:0045580 19 0.018
negative regulation of viral entry into host cell GO:0046597 12 0.018
cytokine mediated signaling pathway GO:0019221 109 0.018
regulation of cytokine production GO:0001817 232 0.017
nitrogen compound transport GO:0071705 191 0.017
immune response regulating signaling pathway GO:0002764 97 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
protein polymerization GO:0051258 71 0.017
interleukin 13 production GO:0032616 7 0.017
spindle organization GO:0007051 53 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
protection from natural killer cell mediated cytotoxicity GO:0042270 3 0.016
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.016
multicellular organismal homeostasis GO:0048871 67 0.016
regulation of cell cycle phase transition GO:1901987 126 0.016
muscle organ development GO:0007517 56 0.016
spermatid development GO:0007286 4 0.016
nk t cell proliferation GO:0001866 3 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
production of molecular mediator of immune response GO:0002440 37 0.015
signal transduction by p53 class mediator GO:0072331 72 0.015
nucleoside catabolic process GO:0009164 408 0.015
intracellular transport of viral protein in host cell GO:0019060 4 0.015
protein processing GO:0016485 226 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
oogenesis GO:0048477 2 0.014
positive regulation of protein transport GO:0051222 135 0.014
positive regulation of tumor necrosis factor production GO:0032760 21 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
response to muramyl dipeptide GO:0032495 4 0.014
hematopoietic or lymphoid organ development GO:0048534 186 0.014
positive regulation of innate immune response GO:0045089 79 0.014
viral entry into host cell GO:0046718 24 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.013
regulation of alpha beta t cell activation GO:0046634 13 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
sensory perception GO:0007600 103 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of interleukin 1 secretion GO:0050704 14 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
positive regulation of activated t cell proliferation GO:0042104 11 0.012
protein secretion GO:0009306 98 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.012
entry into other organism involved in symbiotic interaction GO:0051828 25 0.012
regulation of cytokine secretion GO:0050707 57 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
purine nucleotide biosynthetic process GO:0006164 84 0.012
positive regulation of mononuclear cell proliferation GO:0032946 47 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
negative regulation of transport GO:0051051 176 0.011
regulation of viral transcription GO:0046782 34 0.011
protein maturation GO:0051604 233 0.011
antigen receptor mediated signaling pathway GO:0050851 38 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
biological adhesion GO:0022610 331 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
cellular component morphogenesis GO:0032989 314 0.010
regulation of cytokine biosynthetic process GO:0042035 35 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010
single organism cellular localization GO:1902580 332 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
cell killing GO:0001906 34 0.010
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.010
cytokine production involved in immune response GO:0002367 27 0.010
cellular response to lipid GO:0071396 127 0.010
negative regulation of protein processing GO:0010955 142 0.010
cytokine secretion GO:0050663 64 0.010

PSMB9 disease predictions

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 36 0.760
immune system disease DOID:2914 155 0.760
severe combined immunodeficiency DOID:627 10 0.031
combined t cell and b cell immunodeficiency DOID:628 12 0.031
musculoskeletal system disease DOID:17 223 0.018
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014