|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.998
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.413
|
Human |
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.354
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.346
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.324
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.296
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.288
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.277
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.266
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.249
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.217
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.209
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.208
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.189
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.179
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.165
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.158
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.153
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.152
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.152
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.139
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.138
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.137
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.136
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.134
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.134
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.132
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.129
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.128
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.122
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.121
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.118
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.117
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.116
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.115
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.114
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.112
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.112
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.112
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.106
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.102
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.102
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.101
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.101
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.101
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.100
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.099
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.098
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.097
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.096
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.096
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.096
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.094
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.093
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.093
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.092
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.089
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.089
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.087
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.087
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.087
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.085
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.085
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.085
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.084
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.084
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.084
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.083
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.082
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.081
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.080
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.080
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.080
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.077
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.077
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.077
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.077
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.076
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.075
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.075
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.075
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.075
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.075
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.075
|
Mouse |
|
|
system process
|
GO:0003008 |
349 |
0.074
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.074
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.073
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.072
|
|
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.071
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.071
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.071
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.071
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.070
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.070
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.069
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.069
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.068
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.068
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.068
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.068
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.067
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.067
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.067
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.066
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.065
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.065
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.065
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.064
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.064
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.063
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.061
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.061
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.061
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.061
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.060
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.059
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.059
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.058
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.058
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.058
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.057
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.057
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.057
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.056
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.056
|
|
|
|
growth
|
GO:0040007 |
202 |
0.055
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.055
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.055
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.054
|
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
8 |
0.054
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.054
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.054
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.054
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.053
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.053
|
Human Mouse |
|
|
muscle system process
|
GO:0003012 |
81 |
0.053
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.052
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.052
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.052
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.051
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.051
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.051
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.051
|
|
|
|
memory
|
GO:0007613 |
3 |
0.051
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.051
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.050
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.050
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.050
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.049
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.049
|
|
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.048
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.048
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.048
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.048
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.046
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.046
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.045
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.045
|
|
|
|
caveola assembly
|
GO:0070836 |
4 |
0.045
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.045
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.045
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.044
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.044
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.044
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.044
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.044
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.044
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.044
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.043
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.043
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.043
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.043
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.042
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.042
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.042
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.042
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.042
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.041
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.041
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.041
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.040
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.040
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.040
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.040
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.039
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.039
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.039
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.039
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.039
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.038
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.038
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.038
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.038
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.038
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.038
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.038
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.037
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.037
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.037
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.037
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.036
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.036
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.035
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.035
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.035
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.035
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.035
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.035
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.035
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.035
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.035
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.035
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.034
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.034
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.034
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.034
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.034
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.034
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.033
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.033
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.033
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.033
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.032
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.032
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.032
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.032
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.032
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.032
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.032
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.032
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.032
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.032
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.032
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.032
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.032
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.031
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.031
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.031
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.031
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.031
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.031
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.030
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.030
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.030
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.030
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.030
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.030
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.029
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.029
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.029
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.029
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.029
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.029
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.029
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.029
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.028
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.028
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.028
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.028
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.028
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.028
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.028
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.028
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.028
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.028
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.028
|
|
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.028
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.027
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.027
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.027
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.027
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.027
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.027
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.027
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.026
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.026
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.026
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.026
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.026
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.026
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.025
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.025
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.025
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.025
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.025
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.025
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.025
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.025
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.025
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.025
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.025
|
|
|
|
tnfsf11 mediated signaling pathway
|
GO:0071847 |
2 |
0.025
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.024
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.024
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.024
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.024
|
|
|
|
response to high density lipoprotein particle
|
GO:0055099 |
1 |
0.024
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.024
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.024
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.024
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.024
|
|
|
|
positive regulation of epidermal growth factor receptor signaling pathway
|
GO:0045742 |
11 |
0.024
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.024
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.024
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.024
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.023
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.023
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.023
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.023
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.023
|
Human Mouse |
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.023
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.023
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.023
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.023
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.023
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.023
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.023
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.023
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.023
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.023
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.022
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.022
|
|
|
|
head development
|
GO:0060322 |
108 |
0.022
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.022
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.022
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.022
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.022
|
|
|
|
cilium organization
|
GO:0044782 |
68 |
0.022
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.022
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.022
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.022
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.022
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.022
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.021
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.021
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.021
|
|
|
|
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling
|
GO:0071848 |
2 |
0.021
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.021
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.021
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.021
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.021
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.021
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.021
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.020
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.020
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.020
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.020
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.020
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.020
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.020
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.020
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.020
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.020
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.020
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.020
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.020
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.019
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.019
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.019
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.019
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.019
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.019
|
|
|
|
membrane assembly
|
GO:0071709 |
10 |
0.019
|
Human |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.019
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.019
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.019
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.019
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.019
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.019
|
Human |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.019
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.018
|
|
|
|
positive regulation of erbb signaling pathway
|
GO:1901186 |
11 |
0.018
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.018
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.018
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.018
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.018
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.018
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.018
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.018
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.018
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.018
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.018
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.018
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.018
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.018
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.017
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.017
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.017
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.017
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.017
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.017
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.017
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.017
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.017
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.017
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.017
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.017
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.017
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.017
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.017
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
10 |
0.016
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.016
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.016
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.016
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.016
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.016
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.016
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.016
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.016
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.016
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.016
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.016
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.016
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.015
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.015
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.015
|
Mouse |
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.015
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.015
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.015
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.015
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.015
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.015
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.015
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.015
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.015
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.015
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.015
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.015
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.015
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.015
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.015
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.015
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.015
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.015
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.015
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.015
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.015
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.014
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.014
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.014
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.014
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.014
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.014
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.014
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.014
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.014
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.014
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.014
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.014
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.014
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.014
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.014
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.014
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.014
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.014
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.014
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.014
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.014
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.014
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.014
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.014
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.014
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.014
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.014
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.014
|
|