Homo sapiens

54 known processes

HACE1

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

HACE1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 292 0.068
vesicle mediated transport GO:0016192 371 0.060
cytoplasmic transport GO:0016482 379 0.056
post embryonic development GO:0009791 2 0.051
single organism cellular localization GO:1902580 332 0.048
intracellular protein transport GO:0006886 270 0.047
organophosphate catabolic process GO:0046434 430 0.044
transmembrane transport GO:0055085 399 0.042
multicellular organismal aging GO:0010259 3 0.041
locomotory behavior GO:0007626 1 0.037
neuromuscular junction development GO:0007528 3 0.036
single organism membrane organization GO:0044802 268 0.036
protein ubiquitination GO:0016567 314 0.035
nucleotide catabolic process GO:0009166 408 0.035
microtubule based process GO:0007017 210 0.034
protein localization to organelle GO:0033365 280 0.034
regulation of cell cycle GO:0051726 393 0.033
purine containing compound catabolic process GO:0072523 411 0.032
protein modification by small protein conjugation GO:0032446 342 0.032
protein localization to membrane GO:0072657 160 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
nervous system development GO:0007399 293 0.031
regulation of cell cycle process GO:0010564 266 0.031
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
purine nucleoside triphosphate metabolic process GO:0009144 412 0.030
establishment of protein localization to organelle GO:0072594 172 0.029
endosomal transport GO:0016197 129 0.029
chemical homeostasis GO:0048878 306 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
wnt signaling pathway GO:0016055 156 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
female gamete generation GO:0007292 2 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
regulation of cellular component movement GO:0051270 334 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
organelle assembly GO:0070925 176 0.025
regulation of microtubule cytoskeleton organization GO:0070507 61 0.025
guanosine containing compound catabolic process GO:1901069 239 0.025
cellular response to oxygen containing compound GO:1901701 276 0.024
protein modification by small protein removal GO:0070646 92 0.024
defense response GO:0006952 315 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
purine nucleotide catabolic process GO:0006195 405 0.023
cell division GO:0051301 168 0.023
response to biotic stimulus GO:0009607 276 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
glycosyl compound catabolic process GO:1901658 413 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
oogenesis GO:0048477 2 0.021
spermatid development GO:0007286 4 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
amine metabolic process GO:0009308 44 0.020
cell morphogenesis GO:0000902 296 0.020
memory GO:0007613 3 0.020
determination of adult lifespan GO:0008340 2 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of cell motility GO:2000145 299 0.020
cilium assembly GO:0042384 63 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
regulation of secretion GO:0051046 194 0.019
glycoprotein metabolic process GO:0009100 110 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
negative regulation of multicellular organismal process GO:0051241 317 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
cellular lipid metabolic process GO:0044255 303 0.019
negative regulation of cell death GO:0060548 345 0.019
Human
segmentation GO:0035282 4 0.018
anterior posterior axis specification GO:0009948 2 0.018
receptor metabolic process GO:0043112 81 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
protein localization to plasma membrane GO:0072659 93 0.018
regulation of cellular ketone metabolic process GO:0010565 50 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
nucleoside catabolic process GO:0009164 408 0.018
cilium morphogenesis GO:0060271 75 0.018
ras protein signal transduction GO:0007265 73 0.018
neural tube patterning GO:0021532 2 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
immune response GO:0006955 307 0.017
blastoderm segmentation GO:0007350 2 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
cell projection organization GO:0030030 252 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
protein catabolic process GO:0030163 325 0.017
plasma membrane organization GO:0007009 115 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
metal ion transport GO:0030001 272 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.016
spermatid differentiation GO:0048515 4 0.016
generation of neurons GO:0048699 152 0.016
chemotaxis GO:0006935 157 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
response to external biotic stimulus GO:0043207 261 0.016
protein targeting GO:0006605 187 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
gtp catabolic process GO:0006184 237 0.016
regulation of protein localization GO:0032880 296 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
gtp metabolic process GO:0046039 239 0.016
ion homeostasis GO:0050801 230 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
oocyte development GO:0048599 1 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
positive regulation of transport GO:0051050 336 0.015
endomembrane system organization GO:0010256 196 0.015
regulation of protein complex assembly GO:0043254 147 0.015
system process GO:0003008 349 0.015
cell projection assembly GO:0030031 126 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
response to oxygen containing compound GO:1901700 369 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
oocyte differentiation GO:0009994 2 0.015
cellular amino acid metabolic process GO:0006520 116 0.015
biological adhesion GO:0022610 331 0.015
central nervous system development GO:0007417 123 0.015
receptor recycling GO:0001881 15 0.014
regulation of microtubule based process GO:0032886 74 0.014
cellular component morphogenesis GO:0032989 314 0.014
associative learning GO:0008306 1 0.014
regulation of organelle assembly GO:1902115 40 0.014
response to wounding GO:0009611 168 0.014
lipid metabolic process GO:0006629 381 0.014
mating GO:0007618 1 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
golgi ribbon formation GO:0090161 3 0.014
organophosphate biosynthetic process GO:0090407 163 0.014
maintenance of location GO:0051235 112 0.014
mitotic cell cycle GO:0000278 326 0.014
response to bacterium GO:0009617 144 0.014
cation transport GO:0006812 331 0.014
photoreceptor cell differentiation GO:0046530 2 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
negative regulation of catalytic activity GO:0043086 335 0.013
neurogenesis GO:0022008 169 0.013
purine ribonucleoside catabolic process GO:0046130 398 0.013
regulation of cell migration GO:0030334 289 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
cell adhesion GO:0007155 325 0.013
hindbrain development GO:0030902 3 0.013
adult locomotory behavior GO:0008344 1 0.013
regulation of translation GO:0006417 89 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
golgi organization GO:0007030 38 0.013
mitotic cell cycle process GO:1903047 286 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
nitrogen compound transport GO:0071705 191 0.013
mrna metabolic process GO:0016071 175 0.013
neurological system process GO:0050877 163 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
cation homeostasis GO:0055080 189 0.013
rab protein signal transduction GO:0032482 4 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
growth GO:0040007 202 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
anion transport GO:0006820 161 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
sequestering of metal ion GO:0051238 24 0.012
interspecies interaction between organisms GO:0044419 156 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
dephosphorylation GO:0016311 209 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
metal ion homeostasis GO:0055065 169 0.012
apoptotic signaling pathway GO:0097190 268 0.012
defense response to bacterium GO:0042742 63 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
rna interference GO:0016246 4 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
cytokine production GO:0001816 247 0.012
positive regulation of immune response GO:0050778 159 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
positive regulation of transferase activity GO:0051347 227 0.012
regulation of cytokine production GO:0001817 232 0.012
response to oxidative stress GO:0006979 121 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
Human
defense response to other organism GO:0098542 129 0.012
cell part morphogenesis GO:0032990 137 0.012
divalent inorganic cation transport GO:0072511 158 0.012
chromatin organization GO:0006325 351 0.012
Human
rhythmic behavior GO:0007622 2 0.012
regulation of locomotion GO:0040012 329 0.012
response to other organism GO:0051707 261 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
taxis GO:0042330 157 0.011
cell development GO:0048468 328 0.011
cell fate determination GO:0001709 3 0.011
ion transmembrane transport GO:0034220 338 0.011
protein polyubiquitination GO:0000209 110 0.011
tripartite regional subdivision GO:0007351 2 0.011
protein import into nucleus GO:0006606 104 0.011
epithelium development GO:0060429 227 0.011
regulation of immune response GO:0050776 201 0.011
cellular ketone metabolic process GO:0042180 80 0.011
cellular homeostasis GO:0019725 196 0.011
regulation of cellular response to stress GO:0080135 244 0.011
regulation of secretion by cell GO:1903530 177 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
single organism membrane fusion GO:0044801 37 0.011
calcium ion transport GO:0006816 147 0.011
atp metabolic process GO:0046034 176 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
innate immune response GO:0045087 178 0.011
positive regulation of immune system process GO:0002684 283 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of growth GO:0040008 165 0.011
response to fungus GO:0009620 4 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
Human
organ formation GO:0048645 3 0.011
cell growth GO:0016049 160 0.011
cell projection morphogenesis GO:0048858 129 0.011
nuclear transport GO:0051169 179 0.010
sequestering of calcium ion GO:0051208 17 0.010
regulation of vesicle mediated transport GO:0060627 130 0.010
protein import GO:0017038 130 0.010
divalent metal ion transport GO:0070838 152 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
translation GO:0006412 132 0.010
regulation of intracellular transport GO:0032386 195 0.010
regulation of gtpase activity GO:0043087 180 0.010
cellular chemical homeostasis GO:0055082 180 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
regulation of protein kinase activity GO:0045859 289 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
response to growth factor GO:0070848 205 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
autophagy GO:0006914 88 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
Human
endocytosis GO:0006897 159 0.010
negative regulation of transferase activity GO:0051348 124 0.010
positive regulation of cell migration GO:0030335 172 0.010
cellular amine metabolic process GO:0044106 41 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
positive regulation of ras gtpase activity GO:0032320 117 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
regulation of transferase activity GO:0051338 355 0.010
positive regulation of protein transport GO:0051222 135 0.010
chromatin modification GO:0016568 298 0.010
Human

HACE1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.418
nervous system disease DOID:863 431 0.418
eye and adnexa disease DOID:1492 150 0.259
eye disease DOID:5614 149 0.259
retinal disease DOID:5679 118 0.150
retinal degeneration DOID:8466 89 0.060
glaucoma DOID:1686 8 0.056
central nervous system disease DOID:331 186 0.031
musculoskeletal system disease DOID:17 223 0.030
disease of metabolism DOID:0014667 295 0.025
connective tissue disease DOID:65 109 0.023
inherited metabolic disorder DOID:655 242 0.015
muscular disease DOID:0080000 114 0.014
muscle tissue disease DOID:66 113 0.014
myopathy DOID:423 104 0.012
neurodegenerative disease DOID:1289 102 0.010