Homo sapiens

170 known processes

LATS1

LATS, large tumor suppressor, homolog 1 (Drosophila)

(Aliases: wts,WARTS)

LATS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hippo signaling GO:0035329 20 0.999
negative regulation of hippo signaling GO:0035331 6 0.956
actin filament based process GO:0030029 224 0.434
actin cytoskeleton organization GO:0030036 207 0.424
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.420
negative regulation of wnt signaling pathway GO:0030178 69 0.382
cell development GO:0048468 328 0.348
Fly
negative regulation of developmental process GO:0051093 247 0.294
Fly
negative regulation of protein modification process GO:0031400 200 0.292
regulation of anatomical structure morphogenesis GO:0022603 286 0.288
Fly
negative regulation of protein metabolic process GO:0051248 391 0.288
determination of adult lifespan GO:0008340 2 0.279
Worm
negative regulation of catalytic activity GO:0043086 335 0.265
positive regulation of developmental process GO:0051094 314 0.252
negative regulation of glial cell proliferation GO:0060253 2 0.250
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.225
regulation of cellular component biogenesis GO:0044087 281 0.219
cellular macromolecular complex assembly GO:0034622 324 0.217
negative regulation of cellular protein metabolic process GO:0032269 353 0.214
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.209
negative regulation of gliogenesis GO:0014014 3 0.208
Fly
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.204
cytoplasmic transport GO:0016482 379 0.193
regulation of actin filament based process GO:0032970 141 0.186
amine metabolic process GO:0009308 44 0.186
cellular amine metabolic process GO:0044106 41 0.183
actin filament organization GO:0007015 128 0.182
intracellular protein transport GO:0006886 270 0.180
multicellular organismal aging GO:0010259 3 0.172
Worm
positive regulation of locomotion GO:0040017 186 0.157
negative regulation of intracellular signal transduction GO:1902532 183 0.154
negative regulation of phosphorus metabolic process GO:0010563 267 0.152
regulation of cellular component movement GO:0051270 334 0.149
epithelial cell differentiation GO:0030855 141 0.144
Mouse Fly
regulation of protein kinase activity GO:0045859 289 0.143
nucleoside catabolic process GO:0009164 408 0.142
tube morphogenesis GO:0035239 95 0.141
Worm
cellular component morphogenesis GO:0032989 314 0.135
Fly
regulation of transferase activity GO:0051338 355 0.134
system process GO:0003008 349 0.133
Worm
gtp catabolic process GO:0006184 237 0.133
cellular amino acid metabolic process GO:0006520 116 0.131
protein autophosphorylation GO:0046777 123 0.130
negative regulation of multicellular organismal process GO:0051241 317 0.130
Fly
regulation of cellular amine metabolic process GO:0033238 11 0.128
positive regulation of cell motility GO:2000147 177 0.127
guanosine containing compound catabolic process GO:1901069 239 0.123
regulation of kinase activity GO:0043549 314 0.123
regulation of cell differentiation GO:0045595 393 0.121
Fly
female gamete generation GO:0007292 2 0.116
Fly
actomyosin structure organization GO:0031032 59 0.115
dephosphorylation GO:0016311 209 0.114
regulation of cellular component size GO:0032535 82 0.114
regulation of protein localization GO:0032880 296 0.114
regulation of locomotion GO:0040012 329 0.112
canonical wnt signaling pathway GO:0060070 116 0.110
positive regulation of phosphorylation GO:0042327 394 0.109
regulation of cell motility GO:2000145 299 0.108
guanosine containing compound metabolic process GO:1901068 244 0.108
regulation of growth GO:0040008 165 0.108
positive regulation of cellular component organization GO:0051130 376 0.107
organelle assembly GO:0070925 176 0.107
circulatory system process GO:0003013 113 0.104
growth GO:0040007 202 0.104
Fly
oogenesis GO:0048477 2 0.103
Fly
regulation of glial cell proliferation GO:0060251 4 0.100
Fly
wnt signaling pathway GO:0016055 156 0.100
regulation of anatomical structure size GO:0090066 101 0.100
negative regulation of cell proliferation GO:0008285 228 0.099
Fly
protein targeting GO:0006605 187 0.098
negative regulation of protein phosphorylation GO:0001933 140 0.098
circulatory system development GO:0072359 262 0.096
digestive tract morphogenesis GO:0048546 56 0.096
Worm
mitotic cell cycle process GO:1903047 286 0.095
regulation of cell migration GO:0030334 289 0.094
regulation of canonical wnt signaling pathway GO:0060828 88 0.093
posttranscriptional regulation of gene expression GO:0010608 213 0.093
organ growth GO:0035265 12 0.092
Fly
cellular protein complex assembly GO:0043623 188 0.092
positive regulation of cellular component biogenesis GO:0044089 158 0.092
gtp metabolic process GO:0046039 239 0.091
positive regulation of organ growth GO:0046622 2 0.090
establishment of protein localization to organelle GO:0072594 172 0.088
negative regulation of transferase activity GO:0051348 124 0.086
protein localization to nucleus GO:0034504 136 0.086
cell morphogenesis GO:0000902 296 0.085
Fly
regulation of wnt signaling pathway GO:0030111 123 0.084
tube development GO:0035295 125 0.084
Worm
cytoplasmic sequestering of protein GO:0051220 12 0.082
blood circulation GO:0008015 113 0.082
cellular response to dna damage stimulus GO:0006974 379 0.082
Fly
single organism cellular localization GO:1902580 332 0.081
purine containing compound catabolic process GO:0072523 411 0.080
regulation of epithelial cell migration GO:0010632 93 0.080
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.079
purine ribonucleoside catabolic process GO:0046130 398 0.079
protein import GO:0017038 130 0.078
regulation of establishment of protein localization GO:0070201 242 0.078
stem cell division GO:0017145 2 0.077
peptidyl serine phosphorylation GO:0018105 101 0.076
negative regulation of phosphorylation GO:0042326 174 0.074
compound eye development GO:0048749 1 0.074
Fly
regulation of neurogenesis GO:0050767 82 0.071
Fly
metanephric nephron epithelium development GO:0072243 4 0.071
nuclear division GO:0000280 128 0.070
oocyte differentiation GO:0009994 2 0.067
mapk cascade GO:0000165 288 0.067
positive regulation of organelle organization GO:0010638 195 0.066
anterior posterior axis specification GO:0009948 2 0.066
purine ribonucleotide catabolic process GO:0009154 404 0.066
positive regulation of cell migration GO:0030335 172 0.066
anatomical structure formation involved in morphogenesis GO:0048646 284 0.065
nuclear import GO:0051170 106 0.065
nucleoside triphosphate catabolic process GO:0009143 394 0.065
regulation of cell development GO:0060284 161 0.065
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.064
ribonucleoprotein complex biogenesis GO:0022613 116 0.063
actin filament bundle organization GO:0061572 54 0.063
nucleoside triphosphate metabolic process GO:0009141 422 0.063
stress fiber assembly GO:0043149 40 0.062
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.062
morphogenesis of a polarized epithelium GO:0001738 3 0.060
positive regulation of protein complex assembly GO:0031334 86 0.060
regulation of protein transport GO:0051223 213 0.060
mitotic cell cycle phase transition GO:0044772 162 0.059
cytokinesis GO:0000910 96 0.059
negative regulation of transport GO:0051051 176 0.058
regulation of gtp catabolic process GO:0033124 180 0.058
regulation of protein localization to nucleus GO:1900180 85 0.058
purine nucleotide catabolic process GO:0006195 405 0.057
regulation of cytoplasmic transport GO:1903649 149 0.056
ribonucleotide catabolic process GO:0009261 405 0.055
regulation of cellular response to stress GO:0080135 244 0.055
establishment of tissue polarity GO:0007164 3 0.055
microtubule cytoskeleton organization GO:0000226 176 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.055
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.055
Fly
positive regulation of cellular component movement GO:0051272 181 0.055
actin filament bundle assembly GO:0051017 54 0.055
protein import into nucleus GO:0006606 104 0.055
organophosphate catabolic process GO:0046434 430 0.054
negative regulation of protein localization to nucleus GO:1900181 34 0.054
establishment of planar polarity GO:0001736 3 0.053
keratinocyte differentiation GO:0030216 36 0.053
Mouse
regulation of intracellular protein transport GO:0033157 123 0.052
regulation of cell morphogenesis GO:0022604 153 0.052
Fly
neurogenesis GO:0022008 169 0.051
Fly
regulation of cell cycle GO:0051726 393 0.051
protein targeting to nucleus GO:0044744 104 0.051
cell morphogenesis involved in differentiation GO:0000904 144 0.051
Fly
oocyte development GO:0048599 1 0.051
nucleotide catabolic process GO:0009166 408 0.051
epithelium development GO:0060429 227 0.051
Mouse Fly
cell migration involved in gastrulation GO:0042074 1 0.050
positive regulation of cell death GO:0010942 263 0.050
Fly
regulation of nucleotide metabolic process GO:0006140 269 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.049
mitotic cell cycle GO:0000278 326 0.049
positive regulation of endothelial cell migration GO:0010595 39 0.049
negative regulation of hydrolase activity GO:0051346 182 0.047
morphogenesis of embryonic epithelium GO:0016331 4 0.047
regulation of cell growth GO:0001558 135 0.047
endothelial cell migration GO:0043542 86 0.047
blood vessel endothelial cell migration GO:0043534 42 0.046
neural tube formation GO:0001841 3 0.046
regulation of endothelial cell migration GO:0010594 67 0.046
negative regulation of vasculature development GO:1901343 43 0.046
angiogenesis GO:0001525 147 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.046
regulation of protein targeting GO:1903533 91 0.045
cell growth GO:0016049 160 0.045
neuromuscular junction development GO:0007528 3 0.044
regulation of actin cytoskeleton organization GO:0032956 116 0.044
post embryonic development GO:0009791 2 0.043
Worm
actin filament polymerization GO:0030041 45 0.043
positive regulation of actin filament bundle assembly GO:0032233 25 0.043
glycosyl compound catabolic process GO:1901658 413 0.043
blastoderm segmentation GO:0007350 2 0.043
single organism cell adhesion GO:0098602 179 0.042
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.042
negative regulation of cell differentiation GO:0045596 171 0.042
Fly
single organism membrane organization GO:0044802 268 0.041
anterior posterior axis specification embryo GO:0008595 2 0.041
small gtpase mediated signal transduction GO:0007264 78 0.041
purine nucleoside catabolic process GO:0006152 398 0.041
microtubule based process GO:0007017 210 0.041
tripartite regional subdivision GO:0007351 2 0.041
protein localization to organelle GO:0033365 280 0.040
endomembrane system organization GO:0010256 196 0.040
muscle structure development GO:0061061 98 0.039
vasculature development GO:0001944 181 0.039
regulation of heart growth GO:0060420 4 0.039
regulation of angiogenesis GO:0045765 92 0.039
negative regulation of vascular permeability GO:0043116 7 0.039
response to fungus GO:0009620 4 0.038
metanephric nephron tubule development GO:0072234 3 0.038
positive regulation of axon extension GO:0045773 4 0.038
regulation of intracellular transport GO:0032386 195 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.038
positive regulation of protein phosphorylation GO:0001934 313 0.038
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.038
Fly
membrane organization GO:0061024 292 0.038
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.037
nucleoside phosphate catabolic process GO:1901292 412 0.037
regulation of peptide transport GO:0090087 62 0.037
negative regulation of protein transport GO:0051224 75 0.037
cell cycle phase transition GO:0044770 173 0.036
cell division GO:0051301 168 0.036
positive regulation of cell differentiation GO:0045597 211 0.035
regulation of protein serine threonine kinase activity GO:0071900 179 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.035
negative regulation of blood vessel morphogenesis GO:2000181 41 0.035
ameboidal type cell migration GO:0001667 135 0.035
Fly
nervous system development GO:0007399 293 0.035
Fly
regulation of gtpase activity GO:0043087 180 0.035
regulation of map kinase activity GO:0043405 108 0.035
signal transduction by p53 class mediator GO:0072331 72 0.035
Fly
chromosome segregation GO:0007059 114 0.035
regulation of mapk cascade GO:0043408 262 0.034
regulation of cardiac muscle cell proliferation GO:0060043 4 0.034
gene silencing by mirna GO:0035195 23 0.034
regulation of protein complex assembly GO:0043254 147 0.034
intrinsic apoptotic signaling pathway GO:0097193 127 0.034
Fly
negative regulation of kinase activity GO:0033673 106 0.034
regulation of purine nucleotide catabolic process GO:0033121 205 0.034
segmentation GO:0035282 4 0.034
striated muscle cell differentiation GO:0051146 43 0.034
regulation of protein import into nucleus GO:0042306 78 0.033
negative regulation of intracellular protein transport GO:0090317 42 0.033
negative regulation of protein kinase activity GO:0006469 98 0.033
rho protein signal transduction GO:0007266 26 0.032
cardiac muscle tissue development GO:0048738 39 0.032
regulation of small gtpase mediated signal transduction GO:0051056 156 0.032
maintenance of location GO:0051235 112 0.032
regulation of blood vessel endothelial cell migration GO:0043535 30 0.032
regulation of cytoskeleton organization GO:0051493 177 0.032
regulation of purine nucleotide metabolic process GO:1900542 264 0.032
i kappab kinase nf kappab signaling GO:0007249 166 0.031
regulation of dephosphorylation GO:0035303 96 0.031
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.031
positive regulation of apoptotic process GO:0043065 246 0.030
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
neuron differentiation GO:0030182 138 0.030
Fly
regulation of nervous system development GO:0051960 88 0.030
Fly
mitotic nuclear division GO:0007067 119 0.030
cell projection organization GO:0030030 252 0.030
Fly
cellular ketone metabolic process GO:0042180 80 0.030
spermatid differentiation GO:0048515 4 0.030
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.029
trachea development GO:0060438 1 0.029
Fly
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.029
regulation of transcription factor import into nucleus GO:0042990 39 0.029
maintenance of location in cell GO:0051651 62 0.029
asymmetric stem cell division GO:0098722 1 0.029
negative regulation of protein import into nucleus GO:0042308 30 0.029
positive regulation of cytoskeleton organization GO:0051495 83 0.029
cell differentiation involved in metanephros development GO:0072202 3 0.029
locomotory behavior GO:0007626 1 0.029
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.028
positive regulation of protein import into nucleus GO:0042307 46 0.028
regulation of apoptotic signaling pathway GO:2001233 175 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
Fly
negative regulation of cytoplasmic transport GO:1903650 46 0.028
neuron projection morphogenesis GO:0048812 50 0.028
Fly
apoptotic signaling pathway GO:0097190 268 0.027
Fly
cellular response to decreased oxygen levels GO:0036294 51 0.027
metanephric tubule development GO:0072170 3 0.027
epithelial cell migration GO:0010631 119 0.027
Fly
protein dephosphorylation GO:0006470 81 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
tissue migration GO:0090130 119 0.027
Fly
inorganic ion transmembrane transport GO:0098660 231 0.027
gastrulation with mouth forming second GO:0001702 1 0.026
negative regulation of angiogenesis GO:0016525 39 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
Human Mouse
protein processing GO:0016485 226 0.026
vascular process in circulatory system GO:0003018 29 0.026
cell adhesion GO:0007155 325 0.026
organelle fission GO:0048285 149 0.026
embryonic epithelial tube formation GO:0001838 4 0.026
rna processing GO:0006396 255 0.026
gastrulation GO:0007369 51 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
spermatid development GO:0007286 4 0.026
biological adhesion GO:0022610 331 0.025
nuclear transport GO:0051169 179 0.025
regulation of hippo signaling GO:0035330 8 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.025
positive regulation of protein transport GO:0051222 135 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
regulation of actin filament length GO:0030832 56 0.025
regulation of phosphatase activity GO:0010921 81 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
regulation of organ growth GO:0046620 7 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
microtubule organizing center organization GO:0031023 62 0.024
regulation of cardiac muscle tissue growth GO:0055021 4 0.024
negative regulation of cellular amine metabolic process GO:0033239 3 0.024
negative regulation of mapk cascade GO:0043409 56 0.024
cardiovascular system development GO:0072358 262 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
response to abiotic stimulus GO:0009628 336 0.023
Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
establishment or maintenance of cell polarity GO:0007163 31 0.022
sensory organ development GO:0007423 52 0.022
Fly
osteoblast differentiation GO:0001649 92 0.022
embryonic morphogenesis GO:0048598 85 0.022
cell part morphogenesis GO:0032990 137 0.022
Fly
cell projection morphogenesis GO:0048858 129 0.022
Fly
peptidyl threonine modification GO:0018210 45 0.022
regulation of gliogenesis GO:0014013 7 0.022
Fly
memory GO:0007613 3 0.022
neurological system process GO:0050877 163 0.022
ribonucleoprotein complex assembly GO:0022618 78 0.021
positive regulation of intracellular protein transport GO:0090316 76 0.021
somatic stem cell division GO:0048103 1 0.021
peptidyl threonine phosphorylation GO:0018107 41 0.021
positive regulation of embryonic development GO:0040019 6 0.021
regulation of osteoblast differentiation GO:0045667 38 0.021
regulation of cell cycle process GO:0010564 266 0.021
regulation of stress fiber assembly GO:0051492 32 0.021
neuron projection development GO:0031175 106 0.021
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
positive regulation of cell development GO:0010720 92 0.021
negative regulation of catabolic process GO:0009895 104 0.021
sodium ion transmembrane transport GO:0035725 59 0.021
response to growth factor GO:0070848 205 0.021
hindbrain development GO:0030902 3 0.021
epidermis development GO:0008544 59 0.021
Mouse
cellular response to hypoxia GO:0071456 51 0.020
ribonucleoside catabolic process GO:0042454 406 0.020
cell type specific apoptotic process GO:0097285 125 0.020
centrosome organization GO:0051297 58 0.020
positive regulation of mapk cascade GO:0043410 190 0.020
ion transmembrane transport GO:0034220 338 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.020
regulation of system process GO:0044057 101 0.020
regulation of neuron differentiation GO:0045664 70 0.020
Fly
somatic muscle development GO:0007525 1 0.020
neuroblast proliferation GO:0007405 4 0.020
embryonic placenta development GO:0001892 1 0.020
chromatin organization GO:0006325 351 0.019
establishment of cell polarity GO:0030010 22 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
cell cycle g2 m phase transition GO:0044839 43 0.019
myosin filament assembly GO:0031034 2 0.019
response to hypoxia GO:0001666 96 0.019
epithelial cell proliferation GO:0050673 128 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.019
negative regulation of jun kinase activity GO:0043508 4 0.019
response to biotic stimulus GO:0009607 276 0.019
asymmetric neuroblast division GO:0055059 1 0.019
blood vessel development GO:0001568 172 0.019
epithelium migration GO:0090132 119 0.019
Fly
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.019
regulation of neuron projection development GO:0010975 57 0.019
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.019
peripheral nervous system development GO:0007422 2 0.019
striated muscle myosin thick filament assembly GO:0071688 2 0.018
positive regulation of cell cycle GO:0045787 140 0.018
regulation of actin polymerization or depolymerization GO:0008064 56 0.018
transcription factor import into nucleus GO:0042991 40 0.018
dna repair GO:0006281 198 0.018
positive regulation of protein localization to nucleus GO:1900182 48 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
single organism nuclear import GO:1902593 104 0.018
positive regulation of intracellular transport GO:0032388 104 0.018
protein catabolic process GO:0030163 325 0.018
cell fate determination GO:0001709 3 0.018
regulation of cell cycle arrest GO:0071156 36 0.018
stress activated protein kinase signaling cascade GO:0031098 94 0.018
negative regulation of cell death GO:0060548 345 0.018
chromatin modification GO:0016568 298 0.017
sister chromatid segregation GO:0000819 54 0.017
positive regulation of cell cycle process GO:0090068 106 0.017
cytoplasmic mrna processing body assembly GO:0033962 10 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
generation of neurons GO:0048699 152 0.017
Fly
protein ubiquitination GO:0016567 314 0.017
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.017
Fly
response to axon injury GO:0048678 1 0.017
embryo development GO:0009790 123 0.017
Worm
myosin filament organization GO:0031033 2 0.017
oxidation reduction process GO:0055114 396 0.017
positive regulation of transcription factor import into nucleus GO:0042993 25 0.016
heart contraction GO:0060047 62 0.016
cellular component assembly involved in morphogenesis GO:0010927 73 0.016
syncytium formation by plasma membrane fusion GO:0000768 2 0.016
taxis GO:0042330 157 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
ras protein signal transduction GO:0007265 73 0.016
protein localization to membrane GO:0072657 160 0.016
regulation of peptidyl serine phosphorylation GO:0033135 50 0.016
response to external biotic stimulus GO:0043207 261 0.016
regulation of ligase activity GO:0051340 29 0.016
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
regulation of vascular permeability GO:0043114 11 0.016
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.016
morphogenesis of an epithelium GO:0002009 60 0.016
immune system development GO:0002520 195 0.016
embryonic hemopoiesis GO:0035162 4 0.016
cell aging GO:0007569 52 0.016
cell junction assembly GO:0034329 67 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
chemotaxis GO:0006935 157 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.015
positive regulation of gliogenesis GO:0014015 4 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of epithelial cell differentiation involved in kidney development GO:2000696 4 0.015
nf kappab import into nucleus GO:0042348 22 0.015
covalent chromatin modification GO:0016569 254 0.015
cellular lipid metabolic process GO:0044255 303 0.015
myoblast fusion GO:0007520 1 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
protein complex localization GO:0031503 31 0.015
regulation of developmental growth GO:0048638 30 0.015
digestive system development GO:0055123 75 0.015
Worm
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
neuron development GO:0048666 113 0.015
Fly
response to radiation GO:0009314 151 0.015
Fly
negative regulation of growth GO:0045926 97 0.015
muscle cell development GO:0055001 29 0.015
negative regulation of organelle organization GO:0010639 126 0.015
cation transmembrane transport GO:0098655 238 0.015
maintenance of protein location GO:0045185 57 0.015
cellular response to oxygen levels GO:0071453 55 0.015
cellular protein catabolic process GO:0044257 261 0.015
hippocampus development GO:0021766 1 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.015
cellular response to hormone stimulus GO:0032870 125 0.015
Human Mouse
cellular response to nutrient levels GO:0031669 69 0.015
neural crest cell development GO:0014032 3 0.015
motor neuron axon guidance GO:0008045 2 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
regulation of dna metabolic process GO:0051052 153 0.014
negative regulation of map kinase activity GO:0043407 27 0.014
cell competition in a multicellular organism GO:0035212 1 0.014
regulation of ubiquitin protein transferase activity GO:0051438 28 0.014
axis elongation GO:0003401 4 0.014
cell projection assembly GO:0030031 126 0.014
excretion GO:0007588 9 0.014
Worm
adult locomotory behavior GO:0008344 1 0.014
mitochondrion organization GO:0007005 156 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
negative regulation of cardiac muscle tissue growth GO:0055022 2 0.014
response to oxidative stress GO:0006979 121 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.014
rhythmic behavior GO:0007622 2 0.014
positive regulation of stress fiber assembly GO:0051496 22 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
cellular response to external stimulus GO:0071496 111 0.014
circadian behavior GO:0048512 2 0.014
action potential GO:0001508 34 0.013
osteoblast development GO:0002076 2 0.013
hemopoiesis GO:0030097 180 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.013
Fly
negative regulation of cell cycle GO:0045786 193 0.013
transmembrane transport GO:0055085 399 0.013
regulation of cell shape GO:0008360 48 0.013
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.013
regulation of transporter activity GO:0032409 82 0.013
regulation of actin filament bundle assembly GO:0032231 36 0.013
regulation of nf kappab import into nucleus GO:0042345 22 0.013
positive regulation of epithelial cell migration GO:0010634 55 0.013
positive regulation of nf kappab import into nucleus GO:0042346 13 0.013
negative regulation of proteolysis GO:0045861 132 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
protein maturation GO:0051604 233 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
histone modification GO:0016570 251 0.013
developmental process involved in reproduction GO:0003006 66 0.013
Fly
regulation of ras gtpase activity GO:0032318 128 0.013
protein acylation GO:0043543 138 0.013
centrosome separation GO:0051299 3 0.013
regulation of protein catabolic process GO:0042176 155 0.012
cytoplasmic sequestering of nf kappab GO:0007253 7 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012

LATS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.030
central nervous system disease DOID:331 186 0.024
nervous system disease DOID:863 431 0.024
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.016
inherited metabolic disorder DOID:655 242 0.016
eye and adnexa disease DOID:1492 150 0.014