Homo sapiens

79 known processes

NME1

non-metastatic cells 1, protein (NM23A) expressed in

(Aliases: NDPK-A,NM23,NDKA,NBS,NM23-H1,NB,NDPKA,GAAD,AWD)

NME1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate biosynthetic process GO:1901293 109 0.992
positive regulation of nucleotide biosynthetic process GO:0030810 38 0.987
nucleotide biosynthetic process GO:0009165 109 0.978
pyrimidine ribonucleoside metabolic process GO:0046131 11 0.959
carbohydrate derivative biosynthetic process GO:1901137 207 0.954
positive regulation of camp biosynthetic process GO:0030819 35 0.938
pyrimidine ribonucleoside biosynthetic process GO:0046132 2 0.936
ribonucleotide biosynthetic process GO:0009260 81 0.916
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 1 0.903
post embryonic development GO:0009791 2 0.880
regulation of camp biosynthetic process GO:0030817 45 0.862
purine containing compound biosynthetic process GO:0072522 88 0.862
positive regulation of developmental process GO:0051094 314 0.855
organophosphate biosynthetic process GO:0090407 163 0.818
organonitrogen compound biosynthetic process GO:1901566 200 0.812
purine nucleotide biosynthetic process GO:0006164 84 0.805
regulation of cell differentiation GO:0045595 393 0.745
protein oligomerization GO:0051259 173 0.737
nucleoside diphosphate metabolic process GO:0009132 16 0.722
nucleoside triphosphate biosynthetic process GO:0009142 20 0.709
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.692
pyrimidine ribonucleoside triphosphate metabolic process GO:0009208 2 0.689
purine ribonucleotide biosynthetic process GO:0009152 79 0.685
vesicle mediated transport GO:0016192 371 0.649
epithelial cell proliferation GO:0050673 128 0.645
regulation of nucleotide biosynthetic process GO:0030808 50 0.643
pyrimidine nucleotide biosynthetic process GO:0006221 2 0.634
camp biosynthetic process GO:0006171 47 0.596
response to fatty acid GO:0070542 13 0.580
cellular amine metabolic process GO:0044106 41 0.578
positive regulation of epithelial cell proliferation GO:0050679 65 0.545
purine ribonucleoside biosynthetic process GO:0046129 23 0.540
ribonucleoside biosynthetic process GO:0042455 25 0.527
cyclic nucleotide biosynthetic process GO:0009190 61 0.522
ribose phosphate biosynthetic process GO:0046390 82 0.521
positive regulation of cellular component organization GO:0051130 376 0.511
camp metabolic process GO:0046058 61 0.509
cellular response to oxygen containing compound GO:1901701 276 0.482
ribonucleoside triphosphate metabolic process GO:0009199 412 0.469
pyrimidine nucleotide metabolic process GO:0006220 6 0.468
protein homotetramerization GO:0051289 28 0.466
protein homooligomerization GO:0051260 100 0.457
pyrimidine containing compound metabolic process GO:0072527 19 0.440
negative regulation of apoptotic process GO:0043066 316 0.437
nucleoside biosynthetic process GO:0009163 26 0.423
positive regulation of cell proliferation GO:0008284 301 0.419
oogenesis GO:0048477 2 0.418
endocytosis GO:0006897 159 0.405
negative regulation of cell death GO:0060548 345 0.396
regulation of camp metabolic process GO:0030814 52 0.396
positive regulation of cellular amine metabolic process GO:0033240 7 0.396
regulation of nucleotide metabolic process GO:0006140 269 0.390
regulation of epithelial cell proliferation GO:0050678 113 0.390
negative regulation of multicellular organismal process GO:0051241 317 0.388
cell development GO:0048468 328 0.368
purine ribonucleoside metabolic process GO:0046128 437 0.361
cellular response to lipid GO:0071396 127 0.348
ribonucleoprotein complex biogenesis GO:0022613 116 0.335
amine metabolic process GO:0009308 44 0.321
pyrimidine nucleoside metabolic process GO:0006213 13 0.309
protein tetramerization GO:0051262 47 0.279
nucleoside diphosphate phosphorylation GO:0006165 12 0.267
nucleoside triphosphate metabolic process GO:0009141 422 0.266
neuron differentiation GO:0030182 138 0.262
negative regulation of programmed cell death GO:0043069 321 0.254
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.246
positive regulation of epidermal cell differentiation GO:0045606 8 0.237
epithelial cell differentiation GO:0030855 141 0.223
neurogenesis GO:0022008 169 0.223
cyclic purine nucleotide metabolic process GO:0052652 60 0.212
pyrimidine containing compound biosynthetic process GO:0072528 4 0.200
leukocyte proliferation GO:0070661 74 0.197
negative regulation of immune system process GO:0002683 136 0.163
response to virus GO:0009615 126 0.161
nucleotide phosphorylation GO:0046939 15 0.161
regulation of cell development GO:0060284 161 0.160
positive regulation of cell differentiation GO:0045597 211 0.160
cell projection organization GO:0030030 252 0.158
cellular macromolecular complex assembly GO:0034622 324 0.155
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.154
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.150
pyrimidine ribonucleotide metabolic process GO:0009218 4 0.147
response to hormone GO:0009725 175 0.139
cyclic nucleotide metabolic process GO:0009187 82 0.137
lipid metabolic process GO:0006629 381 0.137
reproduction GO:0000003 63 0.136
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.126
protein localization to organelle GO:0033365 280 0.124
regulation of cellular amine metabolic process GO:0033238 11 0.118
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.116
secretion by cell GO:0032940 226 0.114
locomotory behavior GO:0007626 1 0.113
organic hydroxy compound metabolic process GO:1901615 147 0.113
epithelium development GO:0060429 227 0.112
gtp metabolic process GO:0046039 239 0.110
leukocyte activation GO:0045321 164 0.106
response to peptide hormone GO:0043434 61 0.102
negative regulation of phosphate metabolic process GO:0045936 267 0.101
integrin mediated signaling pathway GO:0007229 32 0.101
positive regulation of cell development GO:0010720 92 0.099
cellular lipid metabolic process GO:0044255 303 0.098
positive regulation of nucleotide metabolic process GO:0045981 230 0.098
single organism reproductive process GO:0044702 98 0.096
female gamete generation GO:0007292 2 0.095
cellular homeostasis GO:0019725 196 0.092
glycosyl compound biosynthetic process GO:1901659 27 0.088
cellular modified amino acid metabolic process GO:0006575 64 0.088
ribonucleoprotein complex assembly GO:0022618 78 0.087
mrna metabolic process GO:0016071 175 0.087
organophosphate catabolic process GO:0046434 430 0.085
regulation of purine nucleotide metabolic process GO:1900542 264 0.085
positive regulation of camp metabolic process GO:0030816 41 0.082
pyrimidine nucleoside biosynthetic process GO:0046134 3 0.081
response to oxygen containing compound GO:1901700 369 0.081
nervous system development GO:0007399 293 0.080
regulation of keratinocyte differentiation GO:0045616 11 0.079
immune effector process GO:0002252 159 0.077
meiotic chromosome segregation GO:0045132 4 0.074
cellular response to fatty acid GO:0071398 8 0.074
small molecule biosynthetic process GO:0044283 157 0.073
response to glucose GO:0009749 19 0.069
lymphocyte activation GO:0046649 133 0.066
response to peptide GO:1901652 65 0.066
regulation of neuron differentiation GO:0045664 70 0.064
response to oxidative stress GO:0006979 121 0.063
cellular response to oxidative stress GO:0034599 85 0.063
positive regulation of immune system process GO:0002684 283 0.062
guanosine containing compound metabolic process GO:1901068 244 0.061
regulation of epidermis development GO:0045682 19 0.060
response to other organism GO:0051707 261 0.059
lipid biosynthetic process GO:0008610 177 0.057
leukocyte differentiation GO:0002521 98 0.056
sulfur compound metabolic process GO:0006790 101 0.055
positive regulation of epidermis development GO:0045684 11 0.054
regulation of growth GO:0040008 165 0.052
organelle assembly GO:0070925 176 0.052
cellular amino acid metabolic process GO:0006520 116 0.051
response to nitrogen compound GO:1901698 184 0.050
cellular glucose homeostasis GO:0001678 11 0.050
monocarboxylic acid metabolic process GO:0032787 185 0.048
fatty acid metabolic process GO:0006631 115 0.047
regulation of leukocyte differentiation GO:1902105 61 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.046
ribonucleoprotein complex subunit organization GO:0071826 81 0.045
positive regulation of growth GO:0045927 58 0.045
negative regulation of developmental process GO:0051093 247 0.045
negative regulation of cell differentiation GO:0045596 171 0.044
cellular component morphogenesis GO:0032989 314 0.043
oocyte differentiation GO:0009994 2 0.042
purine nucleoside triphosphate metabolic process GO:0009144 412 0.041
neuron projection development GO:0031175 106 0.041
positive regulation of transport GO:0051050 336 0.041
secretion GO:0046903 254 0.040
superoxide metabolic process GO:0006801 20 0.040
anatomical structure homeostasis GO:0060249 100 0.040
purine nucleoside biosynthetic process GO:0042451 23 0.039
adult locomotory behavior GO:0008344 1 0.038
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.038
nucleoside monophosphate catabolic process GO:0009125 159 0.038
neuron development GO:0048666 113 0.037
receptor mediated endocytosis GO:0006898 84 0.036
reproductive process GO:0022414 106 0.036
nuclear division GO:0000280 128 0.036
sex differentiation GO:0007548 45 0.036
ctp metabolic process GO:0046036 1 0.035
regulation of myeloid cell differentiation GO:0045637 81 0.035
alpha amino acid metabolic process GO:1901605 72 0.034
transmembrane transport GO:0055085 399 0.034
response to external biotic stimulus GO:0043207 261 0.034
defense response GO:0006952 315 0.034
cellular response to acid chemical GO:0071229 44 0.032
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.032
response to organonitrogen compound GO:0010243 156 0.032
negative regulation of protein processing GO:0010955 142 0.031
rna processing GO:0006396 255 0.031
development of primary sexual characteristics GO:0045137 35 0.031
embryo development ending in birth or egg hatching GO:0009792 34 0.030
regulation of immune response GO:0050776 201 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
response to acid chemical GO:0001101 66 0.029
generation of neurons GO:0048699 152 0.028
ribosomal small subunit export from nucleus GO:0000056 3 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
phospholipid metabolic process GO:0006644 99 0.027
embryo development GO:0009790 123 0.027
cellular ketone metabolic process GO:0042180 80 0.026
positive regulation of leukocyte activation GO:0002696 80 0.026
alcohol metabolic process GO:0006066 114 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
peptidyl serine modification GO:0018209 106 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
epidermal cell differentiation GO:0009913 45 0.024
immune response GO:0006955 307 0.024
regulation of protein binding GO:0043393 66 0.024
ribonucleoside monophosphate metabolic process GO:0009161 187 0.024
negative regulation of apoptotic signaling pathway GO:2001234 97 0.024
regulation of ion transport GO:0043269 189 0.023
regulation of defense response GO:0031347 154 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
negative regulation of myeloid cell differentiation GO:0045638 42 0.023
response to biotic stimulus GO:0009607 276 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
positive regulation of developmental growth GO:0048639 16 0.022
response to monosaccharide GO:0034284 20 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
reproductive system development GO:0061458 56 0.022
reproductive structure development GO:0048608 55 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.021
regulation of leukocyte activation GO:0002694 115 0.021
innate immune response GO:0045087 178 0.021
regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 8 0.021
intracellular protein transport GO:0006886 270 0.020
regulation of neuron projection development GO:0010975 57 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
hemopoiesis GO:0030097 180 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
cell morphogenesis GO:0000902 296 0.019
protein autophosphorylation GO:0046777 123 0.019
rna catabolic process GO:0006401 71 0.019
positive regulation of neuron differentiation GO:0045666 40 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
aging GO:0007568 66 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
cellular response to carbohydrate stimulus GO:0071322 11 0.018
nuclear transcribed mrna catabolic process GO:0000956 48 0.017
protein targeting GO:0006605 187 0.017
positive regulation of multicellular organism growth GO:0040018 6 0.017
mitotic nuclear division GO:0007067 119 0.017
cell activation GO:0001775 213 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
regulation of myeloid leukocyte differentiation GO:0002761 39 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.016
carboxylic acid biosynthetic process GO:0046394 97 0.016
single organism cellular localization GO:1902580 332 0.016
skin development GO:0043588 76 0.016
apoptotic signaling pathway GO:0097190 268 0.016
oocyte development GO:0048599 1 0.016
regulation of cellular component movement GO:0051270 334 0.016
developmental growth GO:0048589 48 0.016
regulation of dna metabolic process GO:0051052 153 0.016
cellular response to glucose stimulus GO:0071333 10 0.015
developmental process involved in reproduction GO:0003006 66 0.015
purine nucleoside monophosphate metabolic process GO:0009126 186 0.015
negative regulation of response to dna damage stimulus GO:2001021 33 0.015
regulation of cell cycle process GO:0010564 266 0.015
negative regulation of nuclear division GO:0051784 25 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
regulation of transmembrane transport GO:0034762 139 0.014
regulation of neurogenesis GO:0050767 82 0.014
negative regulation of leukocyte differentiation GO:1902106 24 0.014
keratinocyte differentiation GO:0030216 36 0.014
nucleoside catabolic process GO:0009164 408 0.013
microtubule based process GO:0007017 210 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
regulation of kinase activity GO:0043549 314 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
regulation of protein transport GO:0051223 213 0.013
lymphocyte proliferation GO:0046651 70 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
spindle organization GO:0007051 53 0.013
membrane organization GO:0061024 292 0.012
oxidation reduction process GO:0055114 396 0.012
b cell proliferation GO:0042100 22 0.012
regulation of developmental growth GO:0048638 30 0.012
cell type specific apoptotic process GO:0097285 125 0.012
small molecule catabolic process GO:0044282 92 0.012
nucleobase biosynthetic process GO:0046112 4 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
atp metabolic process GO:0046034 176 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
response to lipid GO:0033993 206 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
nitrogen compound transport GO:0071705 191 0.012
lipid localization GO:0010876 106 0.012
regulation of mitotic recombination GO:0000019 1 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
negative regulation of dna repair GO:0045738 8 0.011
growth GO:0040007 202 0.011
regulation of cell activation GO:0050865 125 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 6 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
response to growth hormone GO:0060416 11 0.011
epidermis development GO:0008544 59 0.011
positive regulation of neurogenesis GO:0050769 49 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
chemical homeostasis GO:0048878 306 0.011
taxis GO:0042330 157 0.011
regulation of signal transduction by p53 class mediator GO:1901796 26 0.011
positive regulation of cell projection organization GO:0031346 64 0.011
blastocyst development GO:0001824 3 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
regulation of innate immune response GO:0045088 97 0.011
inflammatory response GO:0006954 79 0.011
negative regulation of catabolic process GO:0009895 104 0.011
regulation of mononuclear cell proliferation GO:0032944 65 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
multicellular organism reproduction GO:0032504 42 0.010
positive regulation of keratinocyte differentiation GO:0045618 6 0.010
negative regulation of protein binding GO:0032091 35 0.010
ribonucleoside triphosphate biosynthetic process GO:0009201 12 0.010
cellular response to hexose stimulus GO:0071331 10 0.010
regulation of proteolysis GO:0030162 293 0.010
regulation of nucleoside metabolic process GO:0009118 209 0.010

NME1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.025
immune system disease DOID:2914 155 0.014
nervous system cancer DOID:3093 12 0.003