Homo sapiens

355 known processes

INPP5K

inositol polyphosphate-5-phosphatase K

(Aliases: PPS,SKIP)

INPP5K biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleotide catabolic process GO:0006195 405 0.118
Human
guanosine containing compound metabolic process GO:1901068 244 0.112
Human
cellular amino acid metabolic process GO:0006520 116 0.093
ribonucleoside triphosphate catabolic process GO:0009203 391 0.093
Human
post embryonic development GO:0009791 2 0.093
regulation of cellular amino acid metabolic process GO:0006521 6 0.087
ribonucleoside triphosphate metabolic process GO:0009199 412 0.087
Human
purine containing compound catabolic process GO:0072523 411 0.082
Human
positive regulation of protein phosphorylation GO:0001934 313 0.077
glycosyl compound catabolic process GO:1901658 413 0.074
Human
nucleotide catabolic process GO:0009166 408 0.072
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.072
Human
system process GO:0003008 349 0.070
Mouse
negative regulation of phosphate metabolic process GO:0045936 267 0.070
small gtpase mediated signal transduction GO:0007264 78 0.066
cellular response to growth factor stimulus GO:0071363 197 0.065
nucleoside triphosphate catabolic process GO:0009143 394 0.065
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.064
response to abiotic stimulus GO:0009628 336 0.060
vesicle mediated transport GO:0016192 371 0.060
modification dependent macromolecule catabolic process GO:0043632 212 0.059
cellular macromolecule catabolic process GO:0044265 380 0.059
regulation of gtpase activity GO:0043087 180 0.058
Human
positive regulation of apoptotic process GO:0043065 246 0.057
cellular ketone metabolic process GO:0042180 80 0.054
lipid transport GO:0006869 90 0.052
gtp catabolic process GO:0006184 237 0.052
Human
lipid localization GO:0010876 106 0.052
purine ribonucleoside metabolic process GO:0046128 437 0.051
Human
positive regulation of cell death GO:0010942 263 0.051
organophosphate catabolic process GO:0046434 430 0.050
sulfur compound metabolic process GO:0006790 101 0.049
regulation of transferase activity GO:0051338 355 0.048
cellular response to endogenous stimulus GO:0071495 336 0.048
lipid metabolic process GO:0006629 381 0.047
cell projection organization GO:0030030 252 0.046
regulation of nucleotide catabolic process GO:0030811 205 0.045
Human
negative regulation of protein metabolic process GO:0051248 391 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
Human
neuroblast proliferation GO:0007405 4 0.044
positive regulation of programmed cell death GO:0043068 249 0.043
multicellular organismal aging GO:0010259 3 0.043
internal peptidyl lysine acetylation GO:0018393 97 0.043
ribonucleoside catabolic process GO:0042454 406 0.043
Human
response to oxygen containing compound GO:1901700 369 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
Human
mitotic cell cycle GO:0000278 326 0.041
histone modification GO:0016570 251 0.040
nucleoside catabolic process GO:0009164 408 0.040
Human
positive regulation of catabolic process GO:0009896 310 0.040
Human
regulation of protein kinase activity GO:0045859 289 0.039
protein acetylation GO:0006473 116 0.038
cellular amine metabolic process GO:0044106 41 0.038
metal ion transport GO:0030001 272 0.038
gtp metabolic process GO:0046039 239 0.037
Human
purine ribonucleoside catabolic process GO:0046130 398 0.037
Human
protein ubiquitination GO:0016567 314 0.037
single organism membrane organization GO:0044802 268 0.037
positive regulation of cellular catabolic process GO:0031331 284 0.036
Human
nucleoside phosphate catabolic process GO:1901292 412 0.035
Human
ribonucleotide catabolic process GO:0009261 405 0.035
Human
cellular lipid metabolic process GO:0044255 303 0.035
female gamete generation GO:0007292 2 0.034
positive regulation of hydrolase activity GO:0051345 331 0.034
Human
peptidyl lysine modification GO:0018205 144 0.033
positive regulation of gtpase activity GO:0043547 166 0.033
Human
negative regulation of programmed cell death GO:0043069 321 0.032
acylglycerol metabolic process GO:0006639 27 0.032
purine nucleoside triphosphate catabolic process GO:0009146 392 0.032
Human
oogenesis GO:0048477 2 0.032
mitotic cell cycle process GO:1903047 286 0.032
regulation of cell migration GO:0030334 289 0.031
protein maturation GO:0051604 233 0.031
secretion GO:0046903 254 0.031
histone acetylation GO:0016573 93 0.031
positive regulation of odontogenesis GO:0042482 3 0.031
apoptotic signaling pathway GO:0097190 268 0.031
cellular protein catabolic process GO:0044257 261 0.031
activation of immune response GO:0002253 114 0.031
membrane organization GO:0061024 292 0.030
innate immune response GO:0045087 178 0.030
regulation of proteolysis GO:0030162 293 0.030
oocyte development GO:0048599 1 0.030
defense response GO:0006952 315 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
rho protein signal transduction GO:0007266 26 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
negative regulation of phosphorus metabolic process GO:0010563 267 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
purine nucleoside catabolic process GO:0006152 398 0.028
Human
negative regulation of protein phosphorylation GO:0001933 140 0.028
response to oxygen levels GO:0070482 100 0.028
modification dependent protein catabolic process GO:0019941 209 0.028
guanosine containing compound catabolic process GO:1901069 239 0.028
Human
regulation of mapk cascade GO:0043408 262 0.028
extrinsic apoptotic signaling pathway GO:0097191 119 0.028
regulation of cellular response to growth factor stimulus GO:0090287 76 0.028
protein catabolic process GO:0030163 325 0.028
cardiovascular system development GO:0072358 262 0.027
response to decreased oxygen levels GO:0036293 96 0.027
positive regulation of nucleoside metabolic process GO:0045979 186 0.027
Human
negative regulation of cell death GO:0060548 345 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
determination of adult lifespan GO:0008340 2 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.026
regulation of cellular component movement GO:0051270 334 0.026
cellular macromolecular complex assembly GO:0034622 324 0.026
response to hypoxia GO:0001666 96 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
positive regulation of synaptic transmission GO:0050806 4 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
Human
cell morphogenesis GO:0000902 296 0.025
Human
signal transduction by phosphorylation GO:0023014 297 0.025
regulation of protein localization GO:0032880 296 0.025
secretion by cell GO:0032940 226 0.025
response to growth factor GO:0070848 205 0.025
brain development GO:0007420 97 0.025
asymmetric stem cell division GO:0098722 1 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.024
negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 1 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
endocytosis GO:0006897 159 0.024
regulation of system process GO:0044057 101 0.024
Mouse
mitochondrion organization GO:0007005 156 0.024
oocyte differentiation GO:0009994 2 0.024
head development GO:0060322 108 0.023
amine metabolic process GO:0009308 44 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
regulation of cell motility GO:2000145 299 0.023
regulation of anatomical structure morphogenesis GO:0022603 286 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.023
oxidation reduction process GO:0055114 396 0.023
neuron differentiation GO:0030182 138 0.022
positive regulation of secretion GO:0051047 116 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
Human
nitrogen compound transport GO:0071705 191 0.022
histone h3 acetylation GO:0043966 45 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
Human
vasculature development GO:0001944 181 0.022
negative regulation of endothelial cell migration GO:0010596 29 0.022
negative regulation of protein modification process GO:0031400 200 0.022
protein modification by small protein conjugation GO:0032446 342 0.021
chemotaxis GO:0006935 157 0.021
neuromuscular junction development GO:0007528 3 0.021
positive regulation of nucleotide metabolic process GO:0045981 230 0.021
Human
regeneration GO:0031099 4 0.021
negative regulation of cell adhesion GO:0007162 64 0.021
cytokine production GO:0001816 247 0.021
regulation of cell cycle GO:0051726 393 0.021
rna processing GO:0006396 255 0.021
negative regulation of developmental process GO:0051093 247 0.021
rna splicing GO:0008380 131 0.020
mrna metabolic process GO:0016071 175 0.020
cell division GO:0051301 168 0.020
positive regulation of kinase activity GO:0033674 204 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
proteasomal protein catabolic process GO:0010498 176 0.020
negative regulation of cellular response to hepatocyte growth factor stimulus GO:2001113 1 0.020
cellular response to oxygen levels GO:0071453 55 0.020
cell part morphogenesis GO:0032990 137 0.019
Human
cell growth GO:0016049 160 0.019
spermatid differentiation GO:0048515 4 0.019
hemopoiesis GO:0030097 180 0.019
positive regulation of immune system process GO:0002684 283 0.019
response to hormone GO:0009725 175 0.019
ubiquitin dependent protein catabolic process GO:0006511 206 0.019
ion homeostasis GO:0050801 230 0.019
nervous system development GO:0007399 293 0.019
biological adhesion GO:0022610 331 0.019
positive regulation of gtp catabolic process GO:0033126 166 0.019
Human
response to cytokine GO:0034097 232 0.019
regulation of endopeptidase activity GO:0052548 170 0.019
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.019
negative regulation of axonogenesis GO:0050771 4 0.019
regulation of secretion GO:0051046 194 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
stem cell division GO:0017145 2 0.019
receptor internalization GO:0031623 43 0.018
negative regulation of cellular component movement GO:0051271 106 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
tissue migration GO:0090130 119 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
regulation of locomotion GO:0040012 329 0.018
protein acylation GO:0043543 138 0.018
organelle fission GO:0048285 149 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
blood vessel development GO:0001568 172 0.018
neuroblast division GO:0055057 1 0.018
chromatin organization GO:0006325 351 0.018
negative regulation of cell migration GO:0030336 102 0.018
monovalent inorganic cation transport GO:0015672 128 0.018
cellular component morphogenesis GO:0032989 314 0.018
Human
positive regulation of phosphorylation GO:0042327 394 0.018
cellular response to toxic substance GO:0097237 4 0.018
mapk cascade GO:0000165 288 0.018
organic hydroxy compound transport GO:0015850 63 0.018
protein processing GO:0016485 226 0.018
regulation of ion transport GO:0043269 189 0.017
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.017
segmentation GO:0035282 4 0.017
positive regulation of protein kinase activity GO:0045860 190 0.017
ceramide transport GO:0035627 3 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
regulation of protein ubiquitination GO:0031396 95 0.017
cellular response to hypoxia GO:0071456 51 0.017
maintenance of location GO:0051235 112 0.017
regulation of hepatocyte growth factor receptor signaling pathway GO:1902202 4 0.017
regulation of protein transport GO:0051223 213 0.017
chromatin modification GO:0016568 298 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
Human
covalent chromatin modification GO:0016569 254 0.017
regulation of dephosphorylation GO:0035303 96 0.017
Mouse
positive regulation of cellular component organization GO:0051130 376 0.017
growth GO:0040007 202 0.017
immune response GO:0006955 307 0.017
translation GO:0006412 132 0.017
glycerolipid biosynthetic process GO:0045017 51 0.016
negative regulation of cell growth GO:0030308 83 0.016
regulation of cell cycle process GO:0010564 266 0.016
immune effector process GO:0002252 159 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
cellular response to decreased oxygen levels GO:0036294 51 0.016
anion transport GO:0006820 161 0.016
protein secretion GO:0009306 98 0.016
spermatid development GO:0007286 4 0.016
dephosphorylation GO:0016311 209 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
mitotic nuclear division GO:0007067 119 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.016
ras protein signal transduction GO:0007265 73 0.016
endosomal transport GO:0016197 129 0.016
protein localization to membrane GO:0072657 160 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
Human
negative regulation of cellular component organization GO:0051129 235 0.015
regulation of macrophage chemotaxis GO:0010758 4 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
central nervous system development GO:0007417 123 0.015
regulation of kinase activity GO:0043549 314 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.015
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.015
regulation of epithelial cell migration GO:0010632 93 0.015
positive regulation of transferase activity GO:0051347 227 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
organophosphate biosynthetic process GO:0090407 163 0.014
negative regulation of locomotion GO:0040013 118 0.014
response to organonitrogen compound GO:0010243 156 0.014
nerve development GO:0021675 4 0.014
circulatory system development GO:0072359 262 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
Human
regulation of proteasomal protein catabolic process GO:0061136 87 0.014
single organism cellular localization GO:1902580 332 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
fatty acid biosynthetic process GO:0006633 46 0.014
regulation of secretion by cell GO:1903530 177 0.014
tissue regeneration GO:0042246 3 0.014
negative regulation of endocytosis GO:0045806 19 0.014
hindbrain development GO:0030902 3 0.014
neurogenesis GO:0022008 169 0.014
signal transduction by p53 class mediator GO:0072331 72 0.014
actin cytoskeleton organization GO:0030036 207 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
Human
regulation of protein processing GO:0070613 150 0.014
regulation of cellular response to hepatocyte growth factor stimulus GO:2001112 1 0.014
response to lipid GO:0033993 206 0.014
microtubule based process GO:0007017 210 0.014
vacuole organization GO:0007033 44 0.014
taxis GO:0042330 157 0.014
generation of neurons GO:0048699 152 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
nucleus localization GO:0051647 1 0.014
cell type specific apoptotic process GO:0097285 125 0.013
regulation of endocytosis GO:0030100 72 0.013
ossification GO:0001503 121 0.013
regulation of protein catabolic process GO:0042176 155 0.013
glycoprotein metabolic process GO:0009100 110 0.013
regulation of behavior GO:0050795 82 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
cytoplasmic transport GO:0016482 379 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
receptor mediated endocytosis GO:0006898 84 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
lipid biosynthetic process GO:0008610 177 0.013
negative regulation of phosphatase activity GO:0010923 61 0.013
regulation of cellular response to stress GO:0080135 244 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
organelle assembly GO:0070925 176 0.013
Human
peptidyl serine phosphorylation GO:0018105 101 0.013
negative regulation of epithelial cell migration GO:0010633 38 0.013
mrna processing GO:0006397 133 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
cellular ion homeostasis GO:0006873 168 0.013
regulation of translation GO:0006417 89 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
Human
regulation of chemotaxis GO:0050920 74 0.012
locomotory behavior GO:0007626 1 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of transferase activity GO:0051348 124 0.012
muscle structure development GO:0061061 98 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
reproductive process GO:0022414 106 0.012
cell cycle phase transition GO:0044770 173 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
receptor metabolic process GO:0043112 81 0.012
cell chemotaxis GO:0060326 112 0.012
positive regulation of organelle organization GO:0010638 195 0.012
protein deubiquitination GO:0016579 79 0.012
response to bacterium GO:0009617 144 0.012
prostate gland morphogenesis GO:0060512 1 0.012
activation of protein kinase activity GO:0032147 90 0.012
autophagy GO:0006914 88 0.012
response to molecule of bacterial origin GO:0002237 82 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
positive regulation of proteolysis GO:0045862 142 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
positive regulation of transport GO:0051050 336 0.012
Mouse
carbohydrate metabolic process GO:0005975 207 0.012
response to uv GO:0009411 73 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.012
cation transport GO:0006812 331 0.012
mrna splicing via spliceosome GO:0000398 89 0.011
divalent inorganic cation transport GO:0072511 158 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
positive regulation of cytoskeleton organization GO:0051495 83 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
regulation of endothelial cell migration GO:0010594 67 0.011
positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 3 0.011
regulation of t cell activation GO:0050863 77 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of dna metabolic process GO:0051052 153 0.011
protein oligomerization GO:0051259 173 0.011
cellular response to starvation GO:0009267 58 0.011
sensory perception of pain GO:0019233 4 0.011
cellular response to oxidative stress GO:0034599 85 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
regulation of response to external stimulus GO:0032101 222 0.011
cellular response to peptide hormone stimulus GO:0071375 56 0.011
regulation of protein secretion GO:0050708 86 0.011
cranial nerve development GO:0021545 4 0.011
response to transforming growth factor beta GO:0071559 94 0.011
organic anion transport GO:0015711 103 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
embryo development GO:0009790 123 0.011
Mouse
exocytosis GO:0006887 71 0.011
peptidyl serine modification GO:0018209 106 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
cd8 positive alpha beta t cell activation GO:0036037 3 0.011
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
protein modification by small protein removal GO:0070646 92 0.011
regulation of vascular endothelial growth factor signaling pathway GO:1900746 6 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
protein localization to organelle GO:0033365 280 0.011
regulation of body fluid levels GO:0050878 99 0.010
Mouse
positive regulation of cell cycle GO:0045787 140 0.010
regulation of innate immune response GO:0045088 97 0.010
negative regulation of apoptotic signaling pathway GO:2001234 97 0.010
regulation of triglyceride metabolic process GO:0090207 11 0.010
regulation of membrane potential GO:0042391 95 0.010
metencephalon development GO:0022037 2 0.010
intracellular receptor signaling pathway GO:0030522 104 0.010
response to biotic stimulus GO:0009607 276 0.010
meiosis i GO:0007127 4 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
Human
regulation of cell cycle g1 s phase transition GO:1902806 42 0.010
positive regulation of digestive system process GO:0060456 2 0.010
regulation of cell adhesion GO:0030155 166 0.010
regulation of establishment of protein localization GO:0070201 242 0.010
blood vessel morphogenesis GO:0048514 162 0.010
negative regulation of immune system process GO:0002683 136 0.010
endomembrane system organization GO:0010256 196 0.010
Mouse
regulation of apoptotic signaling pathway GO:2001233 175 0.010
histone h4 acetylation GO:0043967 47 0.010
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.010
proteoglycan catabolic process GO:0030167 3 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010

INPP5K disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.029
nervous system disease DOID:863 431 0.029
musculoskeletal system disease DOID:17 223 0.021
connective tissue disease DOID:65 109 0.013
neurodegenerative disease DOID:1289 102 0.013
sensory system disease DOID:0050155 203 0.013
disease of metabolism DOID:0014667 295 0.012
disease of mental health DOID:150 70 0.012
eye and adnexa disease DOID:1492 150 0.011
bone disease DOID:0080001 88 0.011