|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.163
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.124
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.080
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.061
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.061
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.060
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.060
|
|
|
|
regulation of interleukin 1 mediated signaling pathway
|
GO:2000659 |
3 |
0.056
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.053
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.052
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.052
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.052
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.044
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.042
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.040
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.039
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.038
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.037
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.037
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.035
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.035
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.035
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.035
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.035
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.035
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.034
|
|
|
|
negative regulation of interleukin 1 mediated signaling pathway
|
GO:2000660 |
2 |
0.034
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.033
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.033
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.033
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.033
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.033
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.032
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.031
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.031
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.031
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.031
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.030
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.030
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.029
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.029
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.028
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.028
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.028
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.027
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.027
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.027
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.027
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.027
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.026
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.026
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.026
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.025
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.025
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.025
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.025
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.025
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.025
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.024
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.023
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.023
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.023
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.023
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.023
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.023
|
|
|
|
translation
|
GO:0006412 |
132 |
0.022
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.022
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.022
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.022
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.022
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.022
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.022
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.022
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.021
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.021
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.021
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.021
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.021
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.020
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.020
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.020
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.020
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.020
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.020
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.020
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.020
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.020
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.020
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.020
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.020
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.020
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.020
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.019
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.019
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.019
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.019
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.019
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.019
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.019
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.019
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.019
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.019
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.019
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.019
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.018
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.018
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.018
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.018
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.018
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.018
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.018
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.018
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.018
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.017
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.017
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.017
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.017
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.017
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.017
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.017
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.016
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.016
|
|
|
|
memory
|
GO:0007613 |
3 |
0.016
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.016
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.016
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.016
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.016
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.016
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.015
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.015
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.015
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.015
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.015
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.015
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.015
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.015
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.015
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.015
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.015
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.015
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.015
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.015
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.015
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.015
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.015
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.015
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.014
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.014
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.014
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.014
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.014
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.014
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.014
|
|
|
|
head development
|
GO:0060322 |
108 |
0.014
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.014
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.014
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.014
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.014
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.013
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.013
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.013
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.013
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.013
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.013
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.013
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.013
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.013
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.013
|
|
|
|
system process
|
GO:0003008 |
349 |
0.013
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.013
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.013
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.013
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.013
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.013
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.013
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.013
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.013
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.013
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.013
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.012
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.012
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.012
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.012
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.012
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.012
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.012
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.012
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.012
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.012
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.012
|
|
|
|
growth
|
GO:0040007 |
202 |
0.012
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.012
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.012
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.012
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.012
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.012
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.012
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.012
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.012
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.012
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.012
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.012
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.012
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.012
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.011
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.011
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.011
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.011
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.011
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.011
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.011
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.011
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.011
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.011
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.011
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.011
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.011
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.011
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.011
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.011
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.011
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.011
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.011
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.011
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.011
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.011
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.011
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.010
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.010
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.010
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.010
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.010
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.010
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.010
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.010
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.010
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter during mitosis
|
GO:0046022 |
1 |
0.010
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.010
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.010
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.010
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.010
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.010
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.010
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.010
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.010
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.010
|
|