|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.999
|
|
|
|
system process
|
GO:0003008 |
349 |
0.987
|
Fly |
|
|
secretion
|
GO:0046903 |
254 |
0.957
|
Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.911
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.897
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.875
|
Human Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.861
|
Human Fly |
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.849
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.838
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.835
|
Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.835
|
Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.824
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.799
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.783
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.767
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.764
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.708
|
|
|
|
presynaptic membrane assembly
|
GO:0097105 |
1 |
0.702
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.681
|
Human |
|
|
action potential
|
GO:0001508 |
34 |
0.664
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.662
|
Fly |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.658
|
|
|
|
positive regulation of exosomal secretion
|
GO:1903543 |
12 |
0.620
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.616
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.605
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.595
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.581
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.580
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.574
|
Mouse Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.570
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.549
|
Human Fly |
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.546
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.541
|
Worm |
|
|
behavior
|
GO:0007610 |
112 |
0.539
|
Worm Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.525
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.504
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.504
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.504
|
|
|
|
regulation of exosomal secretion
|
GO:1903541 |
12 |
0.486
|
|
|
|
regulation of extracellular vesicular exosome assembly
|
GO:1903551 |
4 |
0.479
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.464
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.438
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.433
|
Fly |
|
|
establishment of blood brain barrier
|
GO:0060856 |
1 |
0.427
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.417
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.392
|
Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.384
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.381
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.366
|
|
|
|
response to caffeine
|
GO:0031000 |
3 |
0.364
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.351
|
Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.322
|
|
|
|
thalamus development
|
GO:0021794 |
2 |
0.308
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.299
|
Worm |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.293
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.292
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.290
|
|
|
|
skin morphogenesis
|
GO:0043589 |
6 |
0.287
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.282
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.279
|
Fly |
|
|
skin development
|
GO:0043588 |
76 |
0.275
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.267
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.267
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.258
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.253
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.241
|
|
|
|
head development
|
GO:0060322 |
108 |
0.240
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.226
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.222
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.219
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.211
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.211
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.205
|
Fly |
|
|
epidermis development
|
GO:0008544 |
59 |
0.202
|
|
|
|
positive regulation of extracellular vesicular exosome assembly
|
GO:1903553 |
4 |
0.201
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.192
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.184
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.183
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.181
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.180
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.180
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.179
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.171
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.171
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.168
|
|
|
|
vocalization behavior
|
GO:0071625 |
11 |
0.165
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.164
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.159
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.158
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.157
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.157
|
Fly |
|
|
brain development
|
GO:0007420 |
97 |
0.149
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.149
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.148
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.148
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.148
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.148
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.144
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.144
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.142
|
|
|
|
growth
|
GO:0040007 |
202 |
0.140
|
Fly |
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.136
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.135
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.134
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.132
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.132
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.131
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.130
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.126
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.126
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.125
|
Fly |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.122
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.120
|
|
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.120
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.119
|
Fly |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.118
|
Worm |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.115
|
Worm |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.113
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.113
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.112
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.112
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.111
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.110
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.107
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.107
|
Fly |
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.106
|
Fly |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.103
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.101
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.101
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.101
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.101
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.100
|
Fly |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.100
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.096
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.095
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.093
|
|
|
|
exosomal secretion
|
GO:1990182 |
15 |
0.093
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.093
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.091
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.090
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.090
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.089
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.089
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.088
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.088
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.087
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.086
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.086
|
Rat |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.086
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.084
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.084
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.084
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.083
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.082
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.080
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.080
|
|
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.079
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.079
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.078
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.078
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.078
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.077
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.077
|
Worm |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.076
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.075
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.075
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.075
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.074
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.073
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.073
|
|
|
|
superior temporal gyrus development
|
GO:0071109 |
2 |
0.072
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.072
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.072
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.072
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.071
|
Worm |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.070
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.069
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.068
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.067
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.066
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.066
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.066
|
Worm |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.065
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.065
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.064
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.064
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.064
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
29 |
0.063
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.062
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.062
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.062
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
24 |
0.062
|
|
|
|
mating
|
GO:0007618 |
1 |
0.061
|
Fly |
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.061
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.061
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.060
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.060
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.059
|
|
|
|
subpallium development
|
GO:0021544 |
2 |
0.059
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.059
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.059
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.058
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.058
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.058
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.058
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.058
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.058
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.058
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.058
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.058
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.057
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.057
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.056
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.056
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.055
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.055
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.055
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.055
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.055
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.055
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.054
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.054
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.054
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.054
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
15 |
0.053
|
Fly |
|
|
cell cell recognition
|
GO:0009988 |
4 |
0.052
|
|
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.052
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.052
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.052
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.051
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.051
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.051
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.051
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.050
|
|
|
|
cognition
|
GO:0050890 |
43 |
0.050
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.050
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.050
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.050
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.049
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.048
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.048
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.048
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.048
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.047
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.046
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.046
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.046
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.046
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.046
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.045
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.045
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.044
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.044
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
5 |
0.044
|
Fly |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.043
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.043
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.043
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.043
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.043
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.043
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.042
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.042
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.042
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.042
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.042
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.042
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.041
|
|
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.041
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.041
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.041
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.041
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.041
|
|
|
|
endothelial cell morphogenesis
|
GO:0001886 |
2 |
0.040
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.040
|
Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.040
|
Fly |
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.039
|
|
|
|
actin crosslink formation
|
GO:0051764 |
1 |
0.039
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.039
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.039
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.039
|
Fly |
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.039
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.039
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.037
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.037
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.037
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.037
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.037
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.036
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.036
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.036
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.036
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.035
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.035
|
Fly |
|
|
anion transport
|
GO:0006820 |
161 |
0.035
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.035
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.035
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.034
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.034
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.033
|
|
|
|
protein localization to synapse
|
GO:0035418 |
2 |
0.033
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.033
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.033
|
Worm |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.032
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.032
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.032
|
Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.032
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.032
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.032
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.032
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.031
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.031
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.031
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.031
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.030
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.030
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.029
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.029
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.029
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.029
|
Fly |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.029
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.029
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.029
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.029
|
|
|
|
adult behavior
|
GO:0030534 |
18 |
0.028
|
Fly |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.028
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.028
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.028
|
|
|
|
glial cell development
|
GO:0021782 |
7 |
0.028
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.028
|
|
|
|
intermediate filament based process
|
GO:0045103 |
17 |
0.028
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.028
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.028
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.028
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.028
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.027
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.027
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.027
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.027
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.027
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.027
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.026
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.026
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.026
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.026
|
|
|
|
positive regulation of ruffle assembly
|
GO:1900029 |
4 |
0.026
|
|
|
|
memory
|
GO:0007613 |
3 |
0.026
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.026
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.026
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.026
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.026
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.026
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.026
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.025
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.025
|
Worm |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.025
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.025
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.025
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.025
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.025
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.025
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.025
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.024
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.024
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.024
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.024
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.024
|
Fly |
|
|
endothelium development
|
GO:0003158 |
33 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.024
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.023
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.023
|
Fly |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.023
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.023
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.023
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.023
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.023
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.023
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.023
|
Fly |
|
|
regulation of synapse organization
|
GO:0050807 |
7 |
0.022
|
Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.022
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.022
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.022
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.022
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.022
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.022
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.022
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.022
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.021
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.021
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.021
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.021
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.021
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.021
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.021
|
Worm Fly |
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.021
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.021
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.021
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.021
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.021
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.021
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.021
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.021
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.021
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.021
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.021
|
|
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.021
|
|
|
|
cell recognition
|
GO:0008037 |
9 |
0.021
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.021
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.021
|
|
|
|
multi organism behavior
|
GO:0051705 |
14 |
0.021
|
Worm Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.021
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.020
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.020
|
|
|
|
negative regulation of actin filament polymerization
|
GO:0030837 |
10 |
0.020
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.020
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.020
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.020
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.020
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.020
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.020
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.020
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.020
|
|
|
|
inner ear development
|
GO:0048839 |
8 |
0.020
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.020
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.019
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
6 |
0.019
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.019
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.019
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.019
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.019
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.019
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.019
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.019
|
|
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.019
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.019
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.019
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.019
|
|
|
|
regulation of cardiac muscle hypertrophy in response to stress
|
GO:1903242 |
2 |
0.019
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.019
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.019
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.018
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.018
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.018
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.018
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.018
|
|
|
|
schwann cell development
|
GO:0014044 |
1 |
0.018
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.018
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.018
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.018
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
13 |
0.018
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.018
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.018
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.018
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.018
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.018
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.018
|
Fly |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.018
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.018
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.018
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
21 |
0.018
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.018
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.018
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.018
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.018
|
Human |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.017
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.017
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.017
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.017
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
|
neuronal ion channel clustering
|
GO:0045161 |
2 |
0.017
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.017
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.017
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.017
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.017
|
|
|
|
respiratory system development
|
GO:0060541 |
22 |
0.017
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.017
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.017
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.017
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.017
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.017
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.017
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.017
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.017
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.017
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.017
|
|
