Homo sapiens

0 known processes

DAD1

defender against cell death 1

(Aliases: OST2)

DAD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein oxidation GO:0018158 5 0.210
negative regulation of apoptotic process GO:0043066 316 0.193
Mouse Worm
regulation of proteolysis GO:0030162 293 0.159
negative regulation of catalytic activity GO:0043086 335 0.159
post embryonic development GO:0009791 2 0.154
Worm
regulation of gtp catabolic process GO:0033124 180 0.149
intracellular protein transport GO:0006886 270 0.146
cytoplasmic transport GO:0016482 379 0.146
regulation of purine nucleotide metabolic process GO:1900542 264 0.145
protein localization to organelle GO:0033365 280 0.145
negative regulation of peptidase activity GO:0010466 91 0.140
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.136
response to oxidative stress GO:0006979 121 0.133
protein processing GO:0016485 226 0.131
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.130
intrinsic apoptotic signaling pathway GO:0097193 127 0.128
regulation of protein processing GO:0070613 150 0.128
positive regulation of catabolic process GO:0009896 310 0.124
nucleoside triphosphate metabolic process GO:0009141 422 0.119
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.117
regulation of establishment of protein localization GO:0070201 242 0.116
regulation of protein maturation GO:1903317 150 0.112
protein maturation GO:0051604 233 0.107
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.106
negative regulation of endopeptidase activity GO:0010951 84 0.105
regulation of endopeptidase activity GO:0052548 170 0.103
cellular ketone metabolic process GO:0042180 80 0.102
regulation of purine nucleotide catabolic process GO:0033121 205 0.101
regulation of apoptotic signaling pathway GO:2001233 175 0.101
guanosine containing compound metabolic process GO:1901068 244 0.099
positive regulation of nucleotide metabolic process GO:0045981 230 0.099
purine ribonucleoside metabolic process GO:0046128 437 0.099
gtp catabolic process GO:0006184 237 0.095
endocytosis GO:0006897 159 0.094
Worm
carboxylic acid biosynthetic process GO:0046394 97 0.094
negative regulation of protein maturation GO:1903318 142 0.094
regulation of nucleoside metabolic process GO:0009118 209 0.091
regulation of intracellular protein transport GO:0033157 123 0.090
regulation of peptidase activity GO:0052547 180 0.088
cellular homeostasis GO:0019725 196 0.088
protein localization to nucleus GO:0034504 136 0.088
negative regulation of proteolysis GO:0045861 132 0.083
regulation of cysteine type endopeptidase activity GO:2000116 127 0.083
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.081
purine nucleoside triphosphate metabolic process GO:0009144 412 0.080
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.079
cellular amino acid metabolic process GO:0006520 116 0.078
cellular response to oxygen containing compound GO:1901701 276 0.077
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.075
female gamete generation GO:0007292 2 0.074
Worm
negative regulation of phosphate metabolic process GO:0045936 267 0.073
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.072
regulation of protein localization GO:0032880 296 0.072
negative regulation of programmed cell death GO:0043069 321 0.071
Mouse Worm
protein targeting GO:0006605 187 0.071
cellular amine metabolic process GO:0044106 41 0.070
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.069
positive regulation of gtpase activity GO:0043547 166 0.069
negative regulation of protein processing GO:0010955 142 0.068
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.068
defense response GO:0006952 315 0.067
hydrogen peroxide metabolic process GO:0042743 20 0.064
cellular response to superoxide GO:0071451 6 0.064
regulation of cell division GO:0051302 116 0.064
ribonucleoside triphosphate catabolic process GO:0009203 391 0.063
negative regulation of protein metabolic process GO:0051248 391 0.062
anatomical structure formation involved in morphogenesis GO:0048646 284 0.061
regulation of response to wounding GO:1903034 101 0.061
negative regulation of apoptotic signaling pathway GO:2001234 97 0.061
purine ribonucleoside catabolic process GO:0046130 398 0.060
cell division GO:0051301 168 0.060
single organism cellular localization GO:1902580 332 0.060
negative regulation of cellular protein metabolic process GO:0032269 353 0.058
single organism carbohydrate metabolic process GO:0044723 193 0.058
oocyte differentiation GO:0009994 2 0.058
regulation of cytoplasmic transport GO:1903649 149 0.057
negative regulation of hydrolase activity GO:0051346 182 0.055
establishment of protein localization to organelle GO:0072594 172 0.055
immune response GO:0006955 307 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.054
reactive oxygen species metabolic process GO:0072593 75 0.054
regulation of gtpase activity GO:0043087 180 0.053
positive regulation of phosphorylation GO:0042327 394 0.053
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
cellular response to hydrogen peroxide GO:0070301 37 0.053
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
locomotory behavior GO:0007626 1 0.052
positive regulation of hydrolase activity GO:0051345 331 0.051
positive regulation of protein phosphorylation GO:0001934 313 0.051
embryo development GO:0009790 123 0.051
Mouse Worm
apoptotic signaling pathway GO:0097190 268 0.051
cellular protein catabolic process GO:0044257 261 0.051
endomembrane system organization GO:0010256 196 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
guanosine containing compound catabolic process GO:1901069 239 0.049
negative regulation of phosphorylation GO:0042326 174 0.049
positive regulation of nucleoside metabolic process GO:0045979 186 0.049
ribonucleoside triphosphate metabolic process GO:0009199 412 0.048
response to reactive oxygen species GO:0000302 61 0.048
regulation of reactive oxygen species metabolic process GO:2000377 41 0.048
proteasomal protein catabolic process GO:0010498 176 0.047
monocarboxylic acid biosynthetic process GO:0072330 67 0.047
negative regulation of intracellular signal transduction GO:1902532 183 0.047
regulation of nucleotide catabolic process GO:0030811 205 0.047
cellular macromolecule catabolic process GO:0044265 380 0.046
nucleocytoplasmic transport GO:0006913 176 0.045
regulation of kinase activity GO:0043549 314 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.045
cellular response to endogenous stimulus GO:0071495 336 0.044
regulation of intracellular transport GO:0032386 195 0.044
neuromuscular junction development GO:0007528 3 0.044
growth GO:0040007 202 0.043
endoplasmic reticulum organization GO:0007029 20 0.043
monocarboxylic acid metabolic process GO:0032787 185 0.043
carbohydrate metabolic process GO:0005975 207 0.043
posttranscriptional regulation of gene expression GO:0010608 213 0.042
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.042
nucleotide catabolic process GO:0009166 408 0.042
signal transduction by phosphorylation GO:0023014 297 0.041
protein targeting to nucleus GO:0044744 104 0.041
cellular response to oxidative stress GO:0034599 85 0.041
glycosyl compound catabolic process GO:1901658 413 0.040
reproduction GO:0000003 63 0.040
Worm
cytokinesis GO:0000910 96 0.039
positive regulation of cellular catabolic process GO:0031331 284 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
nitrogen compound transport GO:0071705 191 0.038
hydrogen peroxide catabolic process GO:0042744 13 0.038
positive regulation of cytokine production GO:0001819 167 0.038
secretion by cell GO:0032940 226 0.038
regulation of cellular response to stress GO:0080135 244 0.037
organic acid biosynthetic process GO:0016053 97 0.037
protein import GO:0017038 130 0.037
small molecule biosynthetic process GO:0044283 157 0.036
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
secretion GO:0046903 254 0.035
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.035
cytokine production GO:0001816 247 0.035
positive regulation of apoptotic process GO:0043065 246 0.035
epithelium development GO:0060429 227 0.035
membrane organization GO:0061024 292 0.035
positive regulation of gtp catabolic process GO:0033126 166 0.035
microtubule based process GO:0007017 210 0.034
regulation of ion transport GO:0043269 189 0.034
single organism membrane organization GO:0044802 268 0.034
response to inorganic substance GO:0010035 127 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
gtp metabolic process GO:0046039 239 0.034
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.034
regulation of protein transport GO:0051223 213 0.033
negative regulation of protein transport GO:0051224 75 0.033
i kappab kinase nf kappab signaling GO:0007249 166 0.033
regulation of cell cycle process GO:0010564 266 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.032
amine metabolic process GO:0009308 44 0.032
dopamine biosynthetic process GO:0042416 4 0.032
purine containing compound catabolic process GO:0072523 411 0.032
adult locomotory behavior GO:0008344 1 0.031
regulation of cytokine production GO:0001817 232 0.031
regulation of response to external stimulus GO:0032101 222 0.031
vitamin k metabolic process GO:0042373 6 0.031
receptor mediated endocytosis GO:0006898 84 0.031
Worm
vesicle mediated transport GO:0016192 371 0.030
Worm
modification dependent macromolecule catabolic process GO:0043632 212 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
ubiquitin dependent protein catabolic process GO:0006511 206 0.029
negative regulation of immune system process GO:0002683 136 0.029
cytosolic calcium ion homeostasis GO:0051480 89 0.029
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
single organism nuclear import GO:1902593 104 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
ras protein signal transduction GO:0007265 73 0.028
negative regulation of transferase activity GO:0051348 124 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
protein catabolic process GO:0030163 325 0.028
cell aging GO:0007569 52 0.028
purine nucleoside catabolic process GO:0006152 398 0.027
multicellular organismal aging GO:0010259 3 0.027
response to hormone GO:0009725 175 0.027
cell death in response to oxidative stress GO:0036473 29 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
nervous system development GO:0007399 293 0.027
regulation of transferase activity GO:0051338 355 0.027
response to other organism GO:0051707 261 0.027
mitochondrion organization GO:0007005 156 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
nuclear transport GO:0051169 179 0.026
regulation of growth GO:0040008 165 0.026
positive regulation of cell death GO:0010942 263 0.026
positive regulation of developmental process GO:0051094 314 0.026
cellular modified amino acid biosynthetic process GO:0042398 15 0.026
reactive oxygen species biosynthetic process GO:1903409 4 0.026
response to oxygen containing compound GO:1901700 369 0.026
calcium ion homeostasis GO:0055074 122 0.026
regulation of membrane potential GO:0042391 95 0.025
negative regulation of cell death GO:0060548 345 0.025
Mouse Worm
cellular response to reactive oxygen species GO:0034614 50 0.025
cation transport GO:0006812 331 0.025
organic hydroxy compound metabolic process GO:1901615 147 0.025
circulatory system process GO:0003013 113 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.025
peptidyl cysteine modification GO:0018198 9 0.024
protein import into nucleus GO:0006606 104 0.024
autophagy GO:0006914 88 0.024
mitotic cell cycle process GO:1903047 286 0.024
response to bacterium GO:0009617 144 0.024
cellular modified amino acid metabolic process GO:0006575 64 0.024
response to wounding GO:0009611 168 0.024
organophosphate catabolic process GO:0046434 430 0.023
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.023
cellular lipid metabolic process GO:0044255 303 0.023
nucleoside catabolic process GO:0009164 408 0.023
protein localization to plasma membrane GO:0072659 93 0.023
alcohol metabolic process GO:0006066 114 0.023
regulation of multi organism process GO:0043900 157 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
determination of adult lifespan GO:0008340 2 0.022
chemical homeostasis GO:0048878 306 0.022
protein localization to membrane GO:0072657 160 0.022
superoxide metabolic process GO:0006801 20 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
alpha amino acid metabolic process GO:1901605 72 0.022
membrane hyperpolarization GO:0060081 1 0.021
metal ion homeostasis GO:0055065 169 0.021
peptidyl glutamic acid modification GO:0018200 4 0.021
response to external biotic stimulus GO:0043207 261 0.021
skeletal system development GO:0001501 79 0.021
regulation of proteasomal protein catabolic process GO:0061136 87 0.021
wnt signaling pathway GO:0016055 156 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
oocyte development GO:0048599 1 0.021
establishment of nucleus localization GO:0040023 1 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
oxidation reduction process GO:0055114 396 0.020
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.019
regulation of cytokinesis GO:0032465 45 0.019
negative regulation of protein modification process GO:0031400 200 0.019
regulation of secretion by cell GO:1903530 177 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
negative regulation of kinase activity GO:0033673 106 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
cellular response to oxygen radical GO:0071450 6 0.019
regulation of protein catabolic process GO:0042176 155 0.018
cellular aldehyde metabolic process GO:0006081 20 0.018
nuclear migration GO:0007097 1 0.018
extrinsic apoptotic signaling pathway GO:0097191 119 0.018
nuclear import GO:0051170 106 0.018
eye photoreceptor cell differentiation GO:0001754 2 0.018
primary alcohol metabolic process GO:0034308 17 0.018
regulation of nucleocytoplasmic transport GO:0046822 98 0.018
regulation of mitochondrial membrane potential GO:0051881 23 0.018
regulation of transmembrane transport GO:0034762 139 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
cell growth GO:0016049 160 0.017
mapk cascade GO:0000165 288 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.017
transmembrane transport GO:0055085 399 0.017
regulation of cell cycle GO:0051726 393 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
single organism reproductive process GO:0044702 98 0.017
Worm
neurogenesis GO:0022008 169 0.017
cell development GO:0048468 328 0.017
Worm
regulation of secretion GO:0051046 194 0.017
mitotic cell cycle GO:0000278 326 0.017
myosin filament organization GO:0031033 2 0.017
anatomical structure homeostasis GO:0060249 100 0.016
negative regulation of transport GO:0051051 176 0.016
ketone catabolic process GO:0042182 3 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.016
plasma membrane organization GO:0007009 115 0.016
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.016
embryo development ending in birth or egg hatching GO:0009792 34 0.016
Mouse Worm
negative regulation of cytoplasmic transport GO:1903650 46 0.016
mitotic cytokinetic process GO:1902410 2 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
reproductive process GO:0022414 106 0.016
Worm
regulation of protein kinase activity GO:0045859 289 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
response to metal ion GO:0010038 84 0.015
interleukin 8 production GO:0032637 51 0.015
skin development GO:0043588 76 0.015
tissue homeostasis GO:0001894 63 0.015
defense response to other organism GO:0098542 129 0.015
regulation of mapk cascade GO:0043408 262 0.015
negative regulation of protein deubiquitination GO:0090086 3 0.015
positive regulation of organelle organization GO:0010638 195 0.015
positive regulation of transport GO:0051050 336 0.015
regulation of peptidyl serine phosphorylation GO:0033135 50 0.015
positive regulation of cell cycle process GO:0090068 106 0.015
endosomal transport GO:0016197 129 0.015
regulation of cellular protein catabolic process GO:1903362 96 0.015
protein ubiquitination GO:0016567 314 0.015
negative regulation of catabolic process GO:0009895 104 0.015
regulation of protein targeting GO:1903533 91 0.014
peptidyl serine modification GO:0018209 106 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.014
establishment of protein localization to plasma membrane GO:0090002 68 0.014
spindle organization GO:0007051 53 0.014
maintenance of protein location GO:0045185 57 0.014
organic hydroxy compound biosynthetic process GO:1901617 71 0.014
catecholamine biosynthetic process GO:0042423 4 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
cytokine secretion GO:0050663 64 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
dopamine uptake involved in synaptic transmission GO:0051583 4 0.013
response to nitrogen compound GO:1901698 184 0.013
oogenesis GO:0048477 2 0.013
Worm
response to biotic stimulus GO:0009607 276 0.013
immune effector process GO:0002252 159 0.013
regulation of protein stability GO:0031647 87 0.013
cell activation GO:0001775 213 0.013
regulation of defense response GO:0031347 154 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
positive regulation of ion transport GO:0043270 87 0.013
response to superoxide GO:0000303 6 0.013
golgi vesicle transport GO:0048193 80 0.013
response to lipid GO:0033993 206 0.013
multicellular organism reproduction GO:0032504 42 0.013
Worm
cellular ion homeostasis GO:0006873 168 0.012
blastoderm segmentation GO:0007350 2 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.012
negative regulation of wnt signaling pathway GO:0030178 69 0.012
regeneration GO:0031099 4 0.012
regulation of cellular component movement GO:0051270 334 0.012
organ morphogenesis GO:0009887 147 0.012
cellular cation homeostasis GO:0030003 163 0.012
protein secretion GO:0009306 98 0.012
cellular response to organonitrogen compound GO:0071417 124 0.012
regulation of protein secretion GO:0050708 86 0.012
rna interference GO:0016246 4 0.012
response to steroid hormone GO:0048545 80 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
actin cytoskeleton organization GO:0030036 207 0.012
macromolecule methylation GO:0043414 97 0.012
dopamine uptake GO:0090494 4 0.012
regulation of locomotion GO:0040012 329 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
response to oxygen radical GO:0000305 6 0.011
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
regulation of interleukin 8 production GO:0032677 49 0.011
removal of superoxide radicals GO:0019430 6 0.011
regulation of cell motility GO:2000145 299 0.011
positive regulation of growth GO:0045927 58 0.011
tissue regeneration GO:0042246 3 0.011
divalent inorganic cation homeostasis GO:0072507 136 0.011
wound healing GO:0042060 115 0.011
peptidyl serine phosphorylation GO:0018105 101 0.011
positive regulation of apoptotic signaling pathway GO:2001235 70 0.011
response to hydrogen peroxide GO:0042542 40 0.011
protein n linked glycosylation via asparagine GO:0018279 10 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
positive regulation of locomotion GO:0040017 186 0.011
cell projection organization GO:0030030 252 0.011
cellular response to lipid GO:0071396 127 0.011
positive regulation of kinase activity GO:0033674 204 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
cellular response to dna damage stimulus GO:0006974 379 0.011
developmental growth GO:0048589 48 0.011
regulation of hemostasis GO:1900046 42 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
response to organic cyclic compound GO:0014070 204 0.011
dna repair GO:0006281 198 0.011
negative regulation of response to dna damage stimulus GO:2001021 33 0.011
response to toxic substance GO:0009636 37 0.011
methylation GO:0032259 106 0.010
blood circulation GO:0008015 113 0.010
regulation of cellular component size GO:0032535 82 0.010
vitamin metabolic process GO:0006766 26 0.010
cellular response to steroid hormone stimulus GO:0071383 37 0.010
nucleus localization GO:0051647 1 0.010
ion transmembrane transport GO:0034220 338 0.010
ion homeostasis GO:0050801 230 0.010
positive regulation of protein secretion GO:0050714 60 0.010
cell morphogenesis GO:0000902 296 0.010

DAD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
cancer DOID:162 167 0.019
disease of cellular proliferation DOID:14566 174 0.019
organ system cancer DOID:0050686 164 0.016