|
|
negative regulation of serine type peptidase activity
|
GO:1902572 |
2 |
0.984
|
Human |
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.923
|
Human |
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.777
|
|
|
|
regulation of phospholipase a2 activity
|
GO:0032429 |
4 |
0.760
|
Human |
|
|
protein heterotetramerization
|
GO:0051290 |
3 |
0.699
|
Human |
|
|
negative regulation of interleukin 8 secretion
|
GO:2000483 |
2 |
0.679
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.615
|
Human |
|
|
regulation of serine type peptidase activity
|
GO:1902571 |
2 |
0.595
|
Human |
|
|
regulation of serine type endopeptidase activity
|
GO:1900003 |
2 |
0.481
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.479
|
Human |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.477
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.477
|
Worm |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.447
|
Human |
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.417
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.396
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.394
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.381
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.377
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.377
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.372
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.371
|
Worm |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.365
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.363
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.349
|
Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.347
|
Human |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.346
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.339
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.334
|
Human |
|
|
bleb assembly
|
GO:0032060 |
6 |
0.331
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.326
|
Human Zebrafish Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.318
|
Human Worm |
|
|
neutrophil apoptotic process
|
GO:0001781 |
2 |
0.313
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.312
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.300
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.299
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.290
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.286
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.265
|
Human |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.252
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.245
|
Human |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.241
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.236
|
Human Worm |
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.235
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.232
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.226
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.219
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.208
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.206
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.201
|
Human |
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.198
|
Human |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.198
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.196
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.185
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.178
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.177
|
Human |
|
|
skin development
|
GO:0043588 |
76 |
0.175
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.173
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.173
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.173
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.172
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.171
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.169
|
Human |
|
|
wound healing
|
GO:0042060 |
115 |
0.166
|
Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.165
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.163
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.162
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.158
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.158
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.157
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.154
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.154
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.152
|
Rat |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.150
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.149
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.139
|
Human Zebrafish Rat |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.138
|
|
|
|
regulation of phospholipase activity
|
GO:0010517 |
26 |
0.134
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.134
|
Human Worm |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.134
|
Human Zebrafish Rat |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.131
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.129
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.129
|
Human |
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.128
|
|
|
|
neutrophil homeostasis
|
GO:0001780 |
3 |
0.128
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.123
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.122
|
Human |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.122
|
Worm |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.122
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.119
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.119
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.117
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.115
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.115
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.113
|
Human Rat |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.111
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.109
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.109
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.109
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.106
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.104
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.103
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.102
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.102
|
|
|
|
system process
|
GO:0003008 |
349 |
0.102
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.101
|
Rat |
|
|
response to hormone
|
GO:0009725 |
175 |
0.101
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.096
|
|
|
|
collagen catabolic process
|
GO:0030574 |
10 |
0.096
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.095
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.092
|
Human |
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.092
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.092
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.090
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.089
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.088
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.088
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.088
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.088
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.087
|
|
|
|
growth
|
GO:0040007 |
202 |
0.087
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
3 |
0.087
|
Human |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.087
|
Worm |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.085
|
Human |
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.085
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.083
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.082
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.082
|
Human |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.082
|
|
|
|
regulation of neutrophil apoptotic process
|
GO:0033029 |
1 |
0.081
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.080
|
Rat |
|
|
lipid localization
|
GO:0010876 |
106 |
0.080
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.080
|
Human |
|
|
protein processing
|
GO:0016485 |
226 |
0.079
|
Human |
|
|
regulation of integrin mediated signaling pathway
|
GO:2001044 |
3 |
0.078
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.076
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.076
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.075
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.075
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.075
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.074
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.073
|
Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.072
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.072
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.071
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.071
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.068
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.067
|
Human |
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.067
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.067
|
Human |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.067
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.065
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.065
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.064
|
Human |
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.062
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.062
|
Human |
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.062
|
Human |
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.061
|
Human |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.061
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.060
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.059
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
3 |
0.059
|
Human |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.058
|
Human |
|
|
neurofilament bundle assembly
|
GO:0033693 |
2 |
0.058
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.058
|
Human |
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.058
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.058
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.057
|
Human |
|
|
cytokinesis
|
GO:0000910 |
96 |
0.057
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.056
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.055
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.055
|
|
|
|
regulation of vasculogenesis
|
GO:2001212 |
3 |
0.054
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.054
|
Human |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.053
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.053
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.052
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.052
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.052
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.051
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.051
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.051
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.051
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.051
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.050
|
Human |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.050
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.050
|
Human |
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.050
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.049
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.049
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.049
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.048
|
Human |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.047
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.047
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.047
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.047
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.046
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.046
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.046
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.044
|
Human Rat |
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.044
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.044
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.044
|
|
|
|
cytokinesis completion of separation
|
GO:0007109 |
3 |
0.044
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.044
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.044
|
Human |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.043
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.043
|
Human |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.043
|
Human |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.042
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.042
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.042
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
3 |
0.042
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.042
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.042
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.041
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.041
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.041
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.041
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.041
|
Worm |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.040
|
Human Rat |
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.040
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.040
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.040
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.040
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.040
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.040
|
Human |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.039
|
Human Rat |
|
|
cytokine production
|
GO:0001816 |
247 |
0.039
|
Human |
|
|
membrane assembly
|
GO:0071709 |
10 |
0.039
|
Human |
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.039
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.039
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.038
|
Human |
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.038
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.038
|
|
|
|
mating
|
GO:0007618 |
1 |
0.038
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.037
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.037
|
|
|
|
renal system process involved in regulation of blood volume
|
GO:0001977 |
4 |
0.037
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.037
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.036
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.036
|
Human |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.036
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
5 |
0.036
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.036
|
Human |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.036
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.036
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.036
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.036
|
|
|
|
peptide cross linking
|
GO:0018149 |
12 |
0.036
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.036
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.036
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.035
|
Human |
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.035
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.035
|
Human |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.035
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.035
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.035
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.035
|
Human |
|
|
endosome organization
|
GO:0007032 |
20 |
0.034
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.034
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.034
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.034
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.034
|
|
|
|
negative regulation of serine type endopeptidase activity
|
GO:1900004 |
2 |
0.033
|
Human |
|
|
neutrophil clearance
|
GO:0097350 |
1 |
0.033
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.033
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.033
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.033
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.033
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.033
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.033
|
|
|
|
regulation of collagen catabolic process
|
GO:0010710 |
3 |
0.033
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.032
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.032
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.032
|
Human Rat |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.032
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.032
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.032
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.032
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.031
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.031
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.031
|
Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.031
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.031
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.030
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.030
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.030
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.030
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.029
|
Human Worm |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.029
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.029
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.029
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.029
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.028
|
|
|
|
cytokinetic process
|
GO:0032506 |
12 |
0.028
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.028
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.028
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.028
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.028
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.028
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.028
|
|
|
|
regulation of rubidium ion transport
|
GO:2000680 |
3 |
0.028
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
3 |
0.027
|
Human |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.027
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.027
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.027
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.027
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.027
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.027
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.027
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.027
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.026
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.026
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.026
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.026
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.025
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.025
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.025
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.025
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.025
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.025
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.025
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.025
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.025
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.024
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.024
|
|
|
|
eosinophil migration
|
GO:0072677 |
10 |
0.024
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.024
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.024
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.023
|
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
15 |
0.023
|
|
|
|
positive regulation of integrin mediated signaling pathway
|
GO:2001046 |
2 |
0.023
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.023
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.023
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.023
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.022
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.022
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.022
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.022
|
|
|
|
intestinal cholesterol absorption
|
GO:0030299 |
4 |
0.022
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.022
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.022
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.022
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.022
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.022
|
|
|
|
basement membrane organization
|
GO:0071711 |
3 |
0.022
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.022
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.021
|
Human |
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
1 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.021
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.021
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.021
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.021
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.021
|
Human |
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.021
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.021
|
Human |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.021
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.021
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.021
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.021
|
Human Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.021
|
|
|
|
sterol transport
|
GO:0015918 |
39 |
0.021
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.021
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.020
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.020
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.020
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.020
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.020
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.020
|
Human |
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.020
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.020
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.020
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.020
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.020
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.020
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
18 |
0.019
|
Worm |
|
|
neuron development
|
GO:0048666 |
113 |
0.019
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.019
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.019
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.019
|
Worm |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.019
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.019
|
Rat |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.019
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.019
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.019
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.018
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.018
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.018
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.018
|
Human |
|
|
leukocyte migration involved in inflammatory response
|
GO:0002523 |
2 |
0.018
|
|
|
|
response to thyroid hormone
|
GO:0097066 |
9 |
0.018
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.018
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.018
|
Human |
|
|
cell matrix adhesion involved in ameboidal cell migration
|
GO:0003366 |
2 |
0.018
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.018
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.018
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.017
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.017
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.017
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.017
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.017
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.017
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.017
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.017
|
Human |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.017
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.017
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.017
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.016
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.016
|
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
20 |
0.016
|
Human |
|
|
exocytosis
|
GO:0006887 |
71 |
0.016
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.016
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.016
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.016
|
Worm |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.016
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.016
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.016
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.016
|
|
|
|
macrophage fusion
|
GO:0034238 |
1 |
0.016
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.016
|
|
|
|
epithelial cell cell adhesion
|
GO:0090136 |
7 |
0.016
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.016
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.016
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.016
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.016
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.016
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.016
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.016
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.016
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.016
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.016
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.015
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.015
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.015
|
Human |
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.015
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.015
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.015
|
Human |
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.015
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.015
|
Worm |
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.015
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.015
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.015
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.015
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.015
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.015
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.015
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.015
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.015
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.015
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.015
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.015
|
|
|
|
regulation of metalloenzyme activity
|
GO:0048552 |
3 |
0.015
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.015
|
Worm |
|
|
sensory perception
|
GO:0007600 |
103 |
0.015
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.014
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.014
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
18 |
0.014
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.014
|
|
|
|
long chain fatty acid transport
|
GO:0015909 |
18 |
0.014
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.014
|
|
|
|
rubidium ion transport
|
GO:0035826 |
4 |
0.014
|
|
|
|
collagen metabolic process
|
GO:0032963 |
28 |
0.014
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.014
|
Human |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.014
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.014
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.014
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.014
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.014
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.013
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.013
|
|
|
|
fatty acid transport
|
GO:0015908 |
25 |
0.013
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.013
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.013
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.013
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.013
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.013
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.013
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.013
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.013
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.013
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.013
|
Rat |
|
|
acid secretion
|
GO:0046717 |
12 |
0.013
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.013
|
|
