|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.881
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.846
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.785
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.754
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.750
|
Human |
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.728
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.679
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.673
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.656
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.597
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.562
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.560
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.553
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.548
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.527
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.486
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.479
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.470
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.456
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.437
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.434
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.421
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.397
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.394
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.391
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.355
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.354
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.350
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.348
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.341
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.334
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.332
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.329
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.325
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.322
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.319
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.313
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.312
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.304
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.302
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.299
|
Human |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.292
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.288
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.281
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.280
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.277
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.272
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.264
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.262
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.254
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.251
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.246
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.243
|
|
|
|
cellular sodium ion homeostasis
|
GO:0006883 |
8 |
0.238
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.234
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.233
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.228
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.227
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.227
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.225
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.223
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.223
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.221
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.218
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.215
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.207
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.206
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.197
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.195
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.193
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.182
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.171
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.170
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.169
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.168
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.167
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.164
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.159
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.159
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.154
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.154
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.153
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.152
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.152
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.146
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.143
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.143
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.142
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.140
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.137
|
|
|
|
head development
|
GO:0060322 |
108 |
0.136
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.135
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.134
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.132
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.127
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.126
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.125
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.124
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.124
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.123
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.123
|
Mouse |
|
|
embryo development
|
GO:0009790 |
123 |
0.122
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.120
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.120
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.119
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.119
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.119
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.118
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.118
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.116
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.115
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.108
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.104
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.104
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.103
|
Human |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.100
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.099
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.098
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.097
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.096
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.092
|
|
|
|
regulation of interleukin 1 mediated signaling pathway
|
GO:2000659 |
3 |
0.092
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.090
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.089
|
Human |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.087
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.087
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.086
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.086
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.084
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.083
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.082
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.081
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.079
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.078
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.078
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.077
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
3 |
0.076
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.076
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.075
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.075
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.073
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.072
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.071
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.071
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.070
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.070
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.069
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.069
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.068
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.067
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.063
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.063
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.062
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.062
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.061
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.061
|
|
|
|
endosome organization
|
GO:0007032 |
20 |
0.060
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.060
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.060
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.059
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.058
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.058
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.058
|
Mouse |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.056
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.055
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.055
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.054
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.054
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.053
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.052
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.052
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.051
|
Human |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.051
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.050
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.049
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.049
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.049
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.047
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.047
|
Mouse |
|
|
acyl coa biosynthetic process
|
GO:0071616 |
6 |
0.047
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.046
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.045
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.045
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.045
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.045
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.044
|
Human |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.044
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.044
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.043
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.043
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.043
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.042
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.041
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.041
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.040
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.039
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.039
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.038
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.037
|
Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.037
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.037
|
Human |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.036
|
|
|
|
aging
|
GO:0007568 |
66 |
0.036
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.036
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.035
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.035
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.035
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.035
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.035
|
|
|
|
tricarboxylic acid cycle
|
GO:0006099 |
4 |
0.034
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.034
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.033
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.033
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.033
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.032
|
|
|
|
thioester metabolic process
|
GO:0035383 |
23 |
0.032
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.032
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.032
|
|
|
|
protein tetramerization
|
GO:0051262 |
47 |
0.032
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.032
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.032
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.031
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.031
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.031
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.031
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.030
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.030
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.030
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.030
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.030
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.030
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.030
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.029
|
Human |
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.028
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.028
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.028
|
Mouse |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.028
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.028
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.027
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.026
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.026
|
Human |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.026
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.025
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.025
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.024
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.024
|
|
|
|
proton transport
|
GO:0015992 |
22 |
0.024
|
|
|
|
translation
|
GO:0006412 |
132 |
0.024
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.023
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.023
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.023
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.023
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.023
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.022
|
|
|
|
negative regulation of interleukin 1 mediated signaling pathway
|
GO:2000660 |
2 |
0.022
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.022
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.022
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.022
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.021
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.021
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.021
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.021
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.021
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.020
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.020
|
|
|
|
acyl coa metabolic process
|
GO:0006637 |
23 |
0.020
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
3 |
0.020
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.020
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.020
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.020
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.020
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.019
|
|
|
|
system process
|
GO:0003008 |
349 |
0.019
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.019
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.019
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.019
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.019
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
41 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.019
|
Human |
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.018
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.018
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.018
|
|
|
|
thioester biosynthetic process
|
GO:0035384 |
6 |
0.018
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.018
|
Human |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.017
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.017
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.017
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.017
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.017
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.017
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.017
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.017
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.017
|
|
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
4 |
0.017
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.017
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.017
|
|
|
|
negative regulation of neurotransmitter transport
|
GO:0051589 |
1 |
0.017
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.016
|
Human |
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.016
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.016
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.016
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.016
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.016
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.016
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.016
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.016
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.016
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.015
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.015
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.015
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.015
|
|
|
|
negative regulation of transcription regulatory region dna binding
|
GO:2000678 |
6 |
0.015
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.015
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
25 |
0.015
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.015
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.015
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.015
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.015
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.015
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.015
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.015
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.015
|
|
|
|
growth
|
GO:0040007 |
202 |
0.015
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.015
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.015
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.015
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.015
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.015
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.015
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.015
|
|
|
|
regulation of transcription regulatory region dna binding
|
GO:2000677 |
15 |
0.015
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.014
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.014
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.014
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.014
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.014
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.014
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.014
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.014
|
Human |
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
10 |
0.014
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.014
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.014
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.014
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.014
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.014
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.014
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.014
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.013
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.013
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.013
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.013
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.013
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.013
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
2 |
0.013
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.013
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.013
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.013
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.013
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.013
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.013
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.013
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.013
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.013
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.013
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.012
|
|
|
|
glycosyl compound biosynthetic process
|
GO:1901659 |
27 |
0.012
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.012
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.012
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.012
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.012
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.012
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.012
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.012
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
15 |
0.012
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.012
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.012
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.012
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.012
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.012
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.012
|
Human |
|
|
regulation of lipase activity
|
GO:0060191 |
37 |
0.012
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.012
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.012
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.011
|
Human |
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.011
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.011
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.011
|
Human |
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.011
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.011
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.011
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.011
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.011
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.011
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.011
|
Human |
|
|
epithelium development
|
GO:0060429 |
227 |
0.011
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.011
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.011
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.011
|
|
|
|
spliceosomal complex assembly
|
GO:0000245 |
17 |
0.011
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
7 |
0.011
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.010
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.010
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.010
|
|
|
|
post golgi vesicle mediated transport
|
GO:0006892 |
36 |
0.010
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.010
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.010
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.010
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.010
|
|
