Homo sapiens

87 known processes

MCM6

minichromosome maintenance complex component 6

(Aliases: Mis5,P105MCM,MCG40308)

MCM6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna dependent dna replication GO:0006261 44 1.000
Yeast Mouse
dna replication initiation GO:0006270 6 1.000
Yeast
dna replication GO:0006260 116 1.000
Yeast Mouse Fly
double strand break repair via homologous recombination GO:0000724 50 0.999
Yeast
recombinational repair GO:0000725 50 0.998
Yeast
protein dna complex assembly GO:0065004 64 0.949
Yeast
dna unwinding involved in dna replication GO:0006268 2 0.948
Yeast Mouse
dna recombination GO:0006310 77 0.941
Yeast
meiosis i GO:0007127 4 0.928
dna strand elongation involved in dna replication GO:0006271 3 0.915
Yeast
dna repair GO:0006281 198 0.899
Yeast
double strand break repair GO:0006302 101 0.885
Yeast
meiotic chromosome segregation GO:0045132 4 0.853
dna conformation change GO:0071103 113 0.823
post embryonic development GO:0009791 2 0.818
reciprocal meiotic recombination GO:0007131 4 0.804
mitotic dna integrity checkpoint GO:0044774 30 0.777
chromatin organization GO:0006325 351 0.756
cellular response to dna damage stimulus GO:0006974 379 0.732
Yeast
regulation of dna metabolic process GO:0051052 153 0.670
dna duplex unwinding GO:0032508 30 0.660
protein dna complex subunit organization GO:0071824 80 0.648
Yeast
cell cycle dna replication GO:0044786 11 0.599
Yeast
dna geometric change GO:0032392 32 0.585
regulation of gene expression epigenetic GO:0040029 73 0.565
g2 dna damage checkpoint GO:0031572 26 0.563
glycosyl compound catabolic process GO:1901658 413 0.513
atp catabolic process GO:0006200 157 0.500
response to biotic stimulus GO:0009607 276 0.479
dna packaging GO:0006323 77 0.470
embryo development GO:0009790 123 0.367
Worm
chromatin modification GO:0016568 298 0.327
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.313
vesicle mediated transport GO:0016192 371 0.310
negative regulation of gene expression epigenetic GO:0045814 19 0.310
cellular macromolecular complex assembly GO:0034622 324 0.267
Yeast
nuclear dna replication GO:0033260 6 0.254
Yeast
regulation of dna replication GO:0006275 68 0.241
chromatin assembly GO:0031497 61 0.237
sex differentiation GO:0007548 45 0.230
Worm
nucleotide biosynthetic process GO:0009165 109 0.228
organelle fission GO:0048285 149 0.213
regulation of meiotic cell cycle GO:0051445 4 0.202
chromatin silencing GO:0006342 12 0.201
cell projection morphogenesis GO:0048858 129 0.198
microtubule based process GO:0007017 210 0.189
reciprocal dna recombination GO:0035825 4 0.180
regulation of cell cycle GO:0051726 393 0.179
neurogenesis GO:0022008 169 0.168
ribonucleoside monophosphate metabolic process GO:0009161 187 0.165
response to metal ion GO:0010038 84 0.158
purine ribonucleoside metabolic process GO:0046128 437 0.156
purine nucleotide catabolic process GO:0006195 405 0.149
purine containing compound catabolic process GO:0072523 411 0.149
organ morphogenesis GO:0009887 147 0.144
purine ribonucleotide catabolic process GO:0009154 404 0.142
negative regulation of cell cycle GO:0045786 193 0.142
nucleoside phosphate catabolic process GO:1901292 412 0.139
ribonucleotide catabolic process GO:0009261 405 0.138
regulation of chromatin silencing GO:0031935 8 0.134
regulation of gene silencing GO:0060968 24 0.127
determination of adult lifespan GO:0008340 2 0.127
ribonucleoside triphosphate metabolic process GO:0009199 412 0.127
regulation of cell cycle process GO:0010564 266 0.120
response to fungus GO:0009620 4 0.120
cell morphogenesis GO:0000902 296 0.118
enzyme linked receptor protein signaling pathway GO:0007167 303 0.118
reproduction GO:0000003 63 0.117
Worm Fly
nucleosome organization GO:0034728 66 0.117
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.107
response to external biotic stimulus GO:0043207 261 0.106
response to other organism GO:0051707 261 0.105
chromosome segregation GO:0007059 114 0.105
purine ribonucleoside catabolic process GO:0046130 398 0.104
response to inorganic substance GO:0010035 127 0.103
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.103
gonad development GO:0008406 34 0.102
Worm
mitotic dna damage checkpoint GO:0044773 28 0.096
regulation of mitotic cell cycle GO:0007346 189 0.095
mitotic cell cycle GO:0000278 326 0.088
nuclear division GO:0000280 128 0.086
female gamete generation GO:0007292 2 0.086
Worm Fly
purine nucleoside monophosphate metabolic process GO:0009126 186 0.085
meiotic cell cycle GO:0051321 13 0.085
dna strand elongation GO:0022616 5 0.084
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.084
negative regulation of meiotic cell cycle GO:0051447 2 0.083
multicellular organismal aging GO:0010259 3 0.079
reproductive process GO:0022414 106 0.078
Worm Fly
organophosphate biosynthetic process GO:0090407 163 0.077
peptidyl serine phosphorylation GO:0018105 101 0.075
purine nucleoside triphosphate metabolic process GO:0009144 412 0.074
embryo development ending in birth or egg hatching GO:0009792 34 0.073
Worm
mitotic cell cycle phase transition GO:0044772 162 0.072
carbohydrate derivative biosynthetic process GO:1901137 207 0.071
single organism reproductive process GO:0044702 98 0.068
Worm Fly
nucleotide catabolic process GO:0009166 408 0.067
regulation of nucleocytoplasmic transport GO:0046822 98 0.066
regulation of dna dependent dna replication initiation GO:0030174 3 0.066
growth GO:0040007 202 0.066
response to abiotic stimulus GO:0009628 336 0.066
cell projection organization GO:0030030 252 0.065
determination of liver left right asymmetry GO:0071910 6 0.065
nucleoside phosphate biosynthetic process GO:1901293 109 0.064
cellular amino acid metabolic process GO:0006520 116 0.060
positive regulation of developmental process GO:0051094 314 0.060
negative regulation of cell cycle process GO:0010948 121 0.060
gene silencing GO:0016458 49 0.059
nucleoside catabolic process GO:0009164 408 0.056
generation of neurons GO:0048699 152 0.053
ribonucleoside triphosphate catabolic process GO:0009203 391 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.052
resolution of meiotic recombination intermediates GO:0000712 3 0.050
sister chromatid cohesion GO:0007062 24 0.049
reproductive system development GO:0061458 56 0.046
Worm
nucleoside monophosphate catabolic process GO:0009125 159 0.045
negative regulation of dna metabolic process GO:0051053 57 0.044
nucleobase biosynthetic process GO:0046112 4 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.043
deoxyribonucleotide metabolic process GO:0009262 6 0.043
response to ionizing radiation GO:0010212 65 0.042
positive regulation of cell proliferation GO:0008284 301 0.042
negative regulation of cell death GO:0060548 345 0.042
negative regulation of mitotic cell cycle GO:0045930 102 0.042
development of primary sexual characteristics GO:0045137 35 0.041
Worm
chromatin remodeling GO:0006338 55 0.041
nucleoside monophosphate metabolic process GO:0009123 191 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.040
nucleoside triphosphate catabolic process GO:0009143 394 0.040
regulation of meiosis GO:0040020 3 0.040
negative regulation of cell cycle phase transition GO:1901988 89 0.038
protein localization to nucleus GO:0034504 136 0.037
reproductive structure development GO:0048608 55 0.037
Worm
cellular component morphogenesis GO:0032989 314 0.037
Fly
regulation of establishment of protein localization GO:0070201 242 0.036
negative regulation of programmed cell death GO:0043069 321 0.034
engulfment of apoptotic cell GO:0043652 2 0.034
developmental process involved in reproduction GO:0003006 66 0.034
Worm Fly
chromosome condensation GO:0030261 15 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.032
organonitrogen compound biosynthetic process GO:1901566 200 0.031
atp metabolic process GO:0046034 176 0.031
peptidyl serine modification GO:0018209 106 0.031
mitotic g2 dna damage checkpoint GO:0007095 7 0.030
regulation of intracellular transport GO:0032386 195 0.029
negative regulation of mitotic anaphase promoting complex activity GO:0060564 4 0.029
covalent chromatin modification GO:0016569 254 0.028
regulation of intracellular protein transport GO:0033157 123 0.027
amine metabolic process GO:0009308 44 0.027
circulatory system development GO:0072359 262 0.025
response to radiation GO:0009314 151 0.025
histone acetylation GO:0016573 93 0.025
mature ribosome assembly GO:0042256 5 0.024
cell part morphogenesis GO:0032990 137 0.024
cellular ketone metabolic process GO:0042180 80 0.023
oogenesis GO:0048477 2 0.023
Worm Fly
negative regulation of apoptotic process GO:0043066 316 0.023
positive regulation of meiosis i GO:0060903 1 0.023
meiotic chromosome separation GO:0051307 3 0.022
meiotic nuclear division GO:0007126 10 0.022
neuron development GO:0048666 113 0.022
cell division GO:0051301 168 0.021
protein heterotetramerization GO:0051290 3 0.020
mitotic g2 m transition checkpoint GO:0044818 9 0.020
neuron projection development GO:0031175 106 0.020
regulation of dna dependent dna replication GO:0090329 19 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
protein acylation GO:0043543 138 0.019
methylation GO:0032259 106 0.019
regulation of protein transport GO:0051223 213 0.018
aging GO:0007568 66 0.018
response to cadmium ion GO:0046686 10 0.018
chromatin assembly or disassembly GO:0006333 78 0.018
ribonucleotide biosynthetic process GO:0009260 81 0.018
response to xenobiotic stimulus GO:0009410 30 0.018
nervous system development GO:0007399 293 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
mitotic cell cycle checkpoint GO:0007093 68 0.018
cellular component assembly involved in morphogenesis GO:0010927 73 0.017
Fly
microtubule cytoskeleton organization GO:0000226 176 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
purine nucleotide biosynthetic process GO:0006164 84 0.016
determination of heart left right asymmetry GO:0061371 8 0.016
pattern specification process GO:0007389 43 0.016
dna integrity checkpoint GO:0031570 71 0.016
alpha amino acid metabolic process GO:1901605 72 0.016
oxidation reduction process GO:0055114 396 0.016
regulation of chromosome organization GO:0033044 103 0.016
meiotic cell cycle process GO:1903046 8 0.016
intracellular protein transport GO:0006886 270 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
pancreas development GO:0031016 19 0.015
response to drug GO:0042493 81 0.015
apoptotic cell clearance GO:0043277 12 0.015
organophosphate catabolic process GO:0046434 430 0.015
sister chromatid segregation GO:0000819 54 0.014
regulation of mitotic cell cycle spindle assembly checkpoint GO:0090266 8 0.014
dna endoreduplication GO:0042023 5 0.014
regulation of cell cycle phase transition GO:1901987 126 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
protein alkylation GO:0008213 74 0.013
regulation of helicase activity GO:0051095 8 0.013
ribosome assembly GO:0042255 9 0.013
leukocyte proliferation GO:0070661 74 0.013
cell cell signaling GO:0007267 155 0.013
Fly
internal protein amino acid acetylation GO:0006475 101 0.012
camera type eye development GO:0043010 25 0.012
positive regulation of meiosis GO:0045836 2 0.012
positive regulation of transport GO:0051050 336 0.012
urate metabolic process GO:0046415 11 0.012
cellular protein complex assembly GO:0043623 188 0.012
heart development GO:0007507 95 0.012
regulation of histone modification GO:0031056 47 0.011
blastocyst development GO:0001824 3 0.011
transcriptional activation by promoter enhancer looping GO:0071733 1 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
cellular amine metabolic process GO:0044106 41 0.011
lymphocyte activation GO:0046649 133 0.011
regulation of protein localization GO:0032880 296 0.011
neuron differentiation GO:0030182 138 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
cardiovascular system development GO:0072358 262 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
purine nucleoside catabolic process GO:0006152 398 0.011
regeneration GO:0031099 4 0.010
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.010
lymphocyte proliferation GO:0046651 70 0.010
apoptotic signaling pathway GO:0097190 268 0.010
response to cytokine GO:0034097 232 0.010

MCM6 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.033
cancer DOID:162 167 0.020
immune system cancer DOID:0060083 36 0.012
organ system cancer DOID:0050686 164 0.012
disease of metabolism DOID:0014667 295 0.009
inherited metabolic disorder DOID:655 242 0.009
carbohydrate metabolic disorder DOID:2978 55 0.001