Homo sapiens

82 known processes

MCM4

minichromosome maintenance complex component 4

(Aliases: P1-CDC21,CDC54,hCdc21,CDC21,MGC33310)

MCM4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication initiation GO:0006270 6 1.000
Yeast
dna dependent dna replication GO:0006261 44 1.000
Yeast Mouse
dna packaging GO:0006323 77 1.000
dna replication GO:0006260 116 0.999
Yeast Mouse Fly
double strand break repair via homologous recombination GO:0000724 50 0.993
Yeast
protein dna complex assembly GO:0065004 64 0.973
Yeast
dna recombination GO:0006310 77 0.972
Yeast
recombinational repair GO:0000725 50 0.962
Yeast
dna conformation change GO:0071103 113 0.958
protein dna complex subunit organization GO:0071824 80 0.892
Yeast
double strand break repair GO:0006302 101 0.869
Yeast
dna repair GO:0006281 198 0.837
Yeast
meiotic chromosome segregation GO:0045132 4 0.818
cellular macromolecular complex assembly GO:0034622 324 0.683
Yeast
dna strand elongation involved in dna replication GO:0006271 3 0.637
Yeast
post embryonic development GO:0009791 2 0.609
Worm
female gamete generation GO:0007292 2 0.527
regulation of dna metabolic process GO:0051052 153 0.516
oogenesis GO:0048477 2 0.484
chromatin assembly or disassembly GO:0006333 78 0.393
reciprocal meiotic recombination GO:0007131 4 0.295
chromatin assembly GO:0031497 61 0.272
atp catabolic process GO:0006200 157 0.265
cellular response to dna damage stimulus GO:0006974 379 0.250
Yeast
meiosis i GO:0007127 4 0.247
positive regulation of cell cycle GO:0045787 140 0.247
mitotic cell cycle phase transition GO:0044772 162 0.240
cell projection organization GO:0030030 252 0.221
organelle fission GO:0048285 149 0.192
protein ubiquitination GO:0016567 314 0.187
negative regulation of programmed cell death GO:0043069 321 0.186
positive regulation of cellular component organization GO:0051130 376 0.176
regulation of gene silencing GO:0060968 24 0.159
reproduction GO:0000003 63 0.145
mitotic nuclear division GO:0007067 119 0.145
regulation of mitotic cell cycle GO:0007346 189 0.140
dna strand elongation GO:0022616 5 0.133
Yeast
mitotic cell cycle GO:0000278 326 0.130
Fly
reproductive process GO:0022414 106 0.120
regulation of chromatin silencing GO:0031935 8 0.113
regulation of dna replication GO:0006275 68 0.109
nuclear dna replication GO:0033260 6 0.103
Yeast
g1 s transition of mitotic cell cycle GO:0000082 78 0.099
protein catabolic process GO:0030163 325 0.096
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.095
regulation of cell cycle process GO:0010564 266 0.094
embryo development GO:0009790 123 0.094
Worm
myosin filament organization GO:0031033 2 0.088
negative regulation of mitotic cell cycle GO:0045930 102 0.087
positive regulation of cell cycle process GO:0090068 106 0.084
dna geometric change GO:0032392 32 0.082
nucleoside monophosphate catabolic process GO:0009125 159 0.082
mitotic cell cycle process GO:1903047 286 0.081
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.080
purine nucleoside triphosphate metabolic process GO:0009144 412 0.079
nuclear division GO:0000280 128 0.077
cellular component morphogenesis GO:0032989 314 0.076
dna duplex unwinding GO:0032508 30 0.076
cell cycle dna replication GO:0044786 11 0.075
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.074
chromatin modification GO:0016568 298 0.073
purine nucleoside catabolic process GO:0006152 398 0.070
chromosome segregation GO:0007059 114 0.070
negative regulation of cell death GO:0060548 345 0.069
cell morphogenesis GO:0000902 296 0.069
regulation of dna dependent dna replication initiation GO:0030174 3 0.066
generation of neurons GO:0048699 152 0.062
nucleoside triphosphate catabolic process GO:0009143 394 0.060
organelle assembly GO:0070925 176 0.059
sister chromatid segregation GO:0000819 54 0.059
negative regulation of cell cycle process GO:0010948 121 0.059
g2 dna damage checkpoint GO:0031572 26 0.057
regulation of nucleotide metabolic process GO:0006140 269 0.055
cytokinesis GO:0000910 96 0.054
determination of adult lifespan GO:0008340 2 0.054
atp metabolic process GO:0046034 176 0.052
myosin filament assembly GO:0031034 2 0.052
cellular component assembly involved in morphogenesis GO:0010927 73 0.051
regulation of nucleotide catabolic process GO:0030811 205 0.051
chromosome condensation GO:0030261 15 0.050
cellular protein complex assembly GO:0043623 188 0.049
nucleoside monophosphate metabolic process GO:0009123 191 0.049
protein modification by small protein conjugation GO:0032446 342 0.047
meiotic chromosome separation GO:0051307 3 0.047
ribonucleoside triphosphate metabolic process GO:0009199 412 0.046
purine ribonucleoside catabolic process GO:0046130 398 0.044
protein oligomerization GO:0051259 173 0.043
negative regulation of gene expression epigenetic GO:0045814 19 0.042
neurogenesis GO:0022008 169 0.042
purine ribonucleoside metabolic process GO:0046128 437 0.042
mitotic dna integrity checkpoint GO:0044774 30 0.041
chromatin organization GO:0006325 351 0.041
cell cell signaling GO:0007267 155 0.041
sex determination GO:0007530 3 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
resolution of meiotic recombination intermediates GO:0000712 3 0.040
neuron differentiation GO:0030182 138 0.040
reproductive system development GO:0061458 56 0.039
reproductive structure development GO:0048608 55 0.039
reciprocal dna recombination GO:0035825 4 0.039
meiotic cell cycle process GO:1903046 8 0.039
positive regulation of mitotic cell cycle GO:0045931 60 0.039
ribonucleotide catabolic process GO:0009261 405 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
ribonucleoside catabolic process GO:0042454 406 0.037
regulation of cell cycle GO:0051726 393 0.037
purine containing compound catabolic process GO:0072523 411 0.036
nucleotide catabolic process GO:0009166 408 0.035
single organism reproductive process GO:0044702 98 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
vesicle mediated transport GO:0016192 371 0.034
Worm
organophosphate catabolic process GO:0046434 430 0.033
pyrimidine nucleoside triphosphate metabolic process GO:0009147 2 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
response to abiotic stimulus GO:0009628 336 0.031
positive regulation of gtp catabolic process GO:0033126 166 0.031
purine nucleotide catabolic process GO:0006195 405 0.031
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
exit from mitosis GO:0010458 10 0.030
mitotic dna damage checkpoint GO:0044773 28 0.030
cell cell signaling involved in cell fate commitment GO:0045168 5 0.030
negative regulation of cell cycle GO:0045786 193 0.029
chromatin silencing GO:0006342 12 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.027
regulation of mitosis GO:0007088 63 0.027
regulation of transcription by chromatin organization GO:0034401 1 0.027
positive regulation of organelle organization GO:0010638 195 0.027
embryo development ending in birth or egg hatching GO:0009792 34 0.027
Worm
response to radiation GO:0009314 151 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.027
positive regulation of developmental process GO:0051094 314 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
glycosyl compound catabolic process GO:1901658 413 0.025
mitotic sister chromatid segregation GO:0000070 53 0.024
positive regulation of cell division GO:0051781 59 0.024
development of primary sexual characteristics GO:0045137 35 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
multicellular organismal aging GO:0010259 3 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
chromosome separation GO:0051304 23 0.021
striated muscle cell differentiation GO:0051146 43 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
mitotic cell cycle checkpoint GO:0007093 68 0.021
neuron development GO:0048666 113 0.021
response to external biotic stimulus GO:0043207 261 0.020
Zebrafish
chromatin remodeling GO:0006338 55 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
regulation of meiotic cell cycle GO:0051445 4 0.019
gtp metabolic process GO:0046039 239 0.019
multicellular organismal reproductive process GO:0048609 40 0.018
positive regulation of gene expression epigenetic GO:0045815 7 0.018
regulation of chromosome organization GO:0033044 103 0.018
growth GO:0040007 202 0.018
negative regulation of chromatin silencing GO:0031936 4 0.017
positive regulation of cell death GO:0010942 263 0.017
regeneration GO:0031099 4 0.017
gonad development GO:0008406 34 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
organ morphogenesis GO:0009887 147 0.016
cell development GO:0048468 328 0.016
cell part morphogenesis GO:0032990 137 0.016
regulation of chromatin assembly or disassembly GO:0001672 6 0.015
oxidation reduction process GO:0055114 396 0.015
regulation of binding GO:0051098 111 0.015
multi organism reproductive process GO:0044703 54 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
cell projection morphogenesis GO:0048858 129 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
intracellular protein transport GO:0006886 270 0.014
response to inorganic substance GO:0010035 127 0.014
regulation of protein catabolic process GO:0042176 155 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
regulation of cell division GO:0051302 116 0.014
sister chromatid cohesion GO:0007062 24 0.014
oocyte maturation GO:0001556 1 0.014
transcriptional activation by promoter enhancer looping GO:0071733 1 0.014
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.013
protein localization to nucleus GO:0034504 136 0.013
methylation GO:0032259 106 0.013
macromolecule methylation GO:0043414 97 0.013
maintenance of dna repeat elements GO:0043570 4 0.013
negative regulation of meiotic cell cycle GO:0051447 2 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
mitochondrial genome maintenance GO:0000002 8 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
cellular amino acid metabolic process GO:0006520 116 0.013
oocyte development GO:0048599 1 0.012
cell cycle checkpoint GO:0000075 117 0.012
regulation of gene expression epigenetic GO:0040029 73 0.012
regulation of mitotic recombination GO:0000019 1 0.012
cell cycle phase transition GO:0044770 173 0.012
sex differentiation GO:0007548 45 0.012
response to light stimulus GO:0009416 87 0.012
developmental process involved in reproduction GO:0003006 66 0.012
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.011
dna replication independent nucleosome organization GO:0034724 27 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
regulation of proteolysis GO:0030162 293 0.011
multicellular organism reproduction GO:0032504 42 0.011
actin filament based process GO:0030029 224 0.011
cell division GO:0051301 168 0.011
blastocyst development GO:0001824 3 0.011
regulation of cellular respiration GO:0043457 4 0.011
gene silencing GO:0016458 49 0.010
dna integrity checkpoint GO:0031570 71 0.010

MCM4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.014
carbohydrate metabolic disorder DOID:2978 55 0.014
inherited metabolic disorder DOID:655 242 0.014
disease of cellular proliferation DOID:14566 174 0.011