Homo sapiens

97 known processes

ISL1

ISL LIM homeobox 1

(Aliases: ISLET1,Isl-1)

ISL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pancreatic a cell differentiation GO:0003310 1 0.289
Zebrafish
spinal cord development GO:0021510 4 0.267
Zebrafish Mouse
neuron fate commitment GO:0048663 2 0.261
Zebrafish Mouse
heart formation GO:0060914 2 0.204
cardiac cell fate determination GO:0060913 3 0.203
specification of organ identity GO:0010092 3 0.182
cardiovascular system development GO:0072358 262 0.173
circulatory system development GO:0072359 262 0.146
regulation of locomotion GO:0040012 329 0.144
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.127
Mouse
regulation of cellular component movement GO:0051270 334 0.118
positive regulation of developmental process GO:0051094 314 0.118
Mouse
regulation of cell differentiation GO:0045595 393 0.115
Mouse
cellular amino acid metabolic process GO:0006520 116 0.115
epithelium development GO:0060429 227 0.114
Zebrafish Fly
negative regulation of cell differentiation GO:0045596 171 0.111
Mouse
ventral spinal cord development GO:0021517 1 0.109
Zebrafish Mouse
cell fate determination GO:0001709 3 0.108
anatomical structure formation involved in morphogenesis GO:0048646 284 0.106
chemical homeostasis GO:0048878 306 0.104
cellular amine metabolic process GO:0044106 41 0.104
organ morphogenesis GO:0009887 147 0.102
cellular response to endogenous stimulus GO:0071495 336 0.096
Rat
organ formation GO:0048645 3 0.091
regulation of cell development GO:0060284 161 0.090
Mouse
regulation of cell motility GO:2000145 299 0.090
regulation of cellular amine metabolic process GO:0033238 11 0.090
nervous system development GO:0007399 293 0.089
Zebrafish Mouse Rat Fly
negative regulation of developmental process GO:0051093 247 0.087
Mouse
amine metabolic process GO:0009308 44 0.087
cell development GO:0048468 328 0.086
Zebrafish Mouse Rat Fly
epithelial cell differentiation GO:0030855 141 0.085
Zebrafish
negative regulation of multicellular organismal process GO:0051241 317 0.083
Mouse
hindbrain development GO:0030902 3 0.082
motor neuron axon guidance GO:0008045 2 0.081
Fly
cellular ketone metabolic process GO:0042180 80 0.080
regulation of cellular amino acid metabolic process GO:0006521 6 0.080
post embryonic development GO:0009791 2 0.079
Worm
regulation of cellular ketone metabolic process GO:0010565 50 0.079
system process GO:0003008 349 0.078
Zebrafish Worm
taxis GO:0042330 157 0.077
Mouse Fly
cell morphogenesis GO:0000902 296 0.076
Zebrafish Mouse Fly
positive regulation of cell differentiation GO:0045597 211 0.075
somatic stem cell maintenance GO:0035019 4 0.075
neuron differentiation GO:0030182 138 0.074
Zebrafish Mouse Rat Fly
cellular component morphogenesis GO:0032989 314 0.072
Zebrafish Mouse Fly
regulation of cell migration GO:0030334 289 0.072
regulation of cell cycle GO:0051726 393 0.070
response to oxygen containing compound GO:1901700 369 0.069
negative regulation of apoptotic process GO:0043066 316 0.067
Mouse
regulation of hormone levels GO:0010817 125 0.067
Rat
response to abiotic stimulus GO:0009628 336 0.066
tissue morphogenesis GO:0048729 96 0.066
Mouse Fly
locomotory behavior GO:0007626 1 0.066
pituitary gland development GO:0021983 2 0.066
Mouse
positive regulation of cell proliferation GO:0008284 301 0.065
Mouse
vasculature development GO:0001944 181 0.064
Mouse
cranial nerve development GO:0021545 4 0.063
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.061
Fly
stem cell differentiation GO:0048863 93 0.060
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.060
regulation of anatomical structure morphogenesis GO:0022603 286 0.060
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.060
cell morphogenesis involved in differentiation GO:0000904 144 0.059
Zebrafish Mouse Fly
biological adhesion GO:0022610 331 0.058
negative regulation of programmed cell death GO:0043069 321 0.057
Mouse
nerve development GO:0021675 4 0.057
Mouse
negative regulation of cellular protein metabolic process GO:0032269 353 0.057
cell projection organization GO:0030030 252 0.057
Zebrafish Mouse Rat Fly
generation of neurons GO:0048699 152 0.056
Zebrafish Mouse Rat Fly
female gamete generation GO:0007292 2 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.053
Fly
central nervous system development GO:0007417 123 0.052
Zebrafish Mouse
embryonic morphogenesis GO:0048598 85 0.051
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.051
Fly
chemotaxis GO:0006935 157 0.051
Mouse Fly
cell differentiation in spinal cord GO:0021515 1 0.050
Zebrafish Mouse
oogenesis GO:0048477 2 0.049
blood vessel development GO:0001568 172 0.049
Mouse
immune system development GO:0002520 195 0.049
Fly
cellular response to oxygen containing compound GO:1901701 276 0.047
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.047
neurogenesis GO:0022008 169 0.045
Zebrafish Mouse Rat Fly
secretion GO:0046903 254 0.044
Rat
cell adhesion GO:0007155 325 0.044
negative regulation of catalytic activity GO:0043086 335 0.044
stem cell development GO:0048864 69 0.043
Mouse
positive regulation of cell motility GO:2000147 177 0.043
metencephalon development GO:0022037 2 0.043
response to organic cyclic compound GO:0014070 204 0.043
Rat
regulation of kinase activity GO:0043549 314 0.043
angiogenesis GO:0001525 147 0.042
Mouse
negative regulation of cellular component organization GO:0051129 235 0.042
head development GO:0060322 108 0.042
Mouse Worm
lipid metabolic process GO:0006629 381 0.042
forelimb morphogenesis GO:0035136 4 0.041
morphogenesis of embryonic epithelium GO:0016331 4 0.041
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.041
chromatin modification GO:0016568 298 0.041
positive regulation of transport GO:0051050 336 0.041
Rat
response to lipid GO:0033993 206 0.041
Rat
embryonic camera type eye development GO:0031076 2 0.040
epithelial cell proliferation GO:0050673 128 0.040
brain development GO:0007420 97 0.040
Mouse
positive regulation of immune system process GO:0002684 283 0.039
multicellular organismal aging GO:0010259 3 0.039
secretion by cell GO:0032940 226 0.039
Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.039
determination of adult lifespan GO:0008340 2 0.039
negative regulation of phosphorus metabolic process GO:0010563 267 0.039
regulation of epithelial cell proliferation GO:0050678 113 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
response to external biotic stimulus GO:0043207 261 0.038
skeletal system development GO:0001501 79 0.037
mitotic cell cycle GO:0000278 326 0.037
single organism membrane organization GO:0044802 268 0.037
cell cell signaling GO:0007267 155 0.037
Rat
positive regulation of cellular component movement GO:0051272 181 0.037
signal transduction by phosphorylation GO:0023014 297 0.037
growth GO:0040007 202 0.036
Zebrafish
heart development GO:0007507 95 0.036
cellular homeostasis GO:0019725 196 0.036
chromatin organization GO:0006325 351 0.036
myeloid cell differentiation GO:0030099 117 0.036
transmembrane transport GO:0055085 399 0.036
hemopoiesis GO:0030097 180 0.036
actin filament based process GO:0030029 224 0.036
ventral spinal cord interneuron differentiation GO:0021514 1 0.035
positive regulation of locomotion GO:0040017 186 0.035
blood vessel morphogenesis GO:0048514 162 0.035
Mouse
single organism cellular localization GO:1902580 332 0.035
cytoplasmic transport GO:0016482 379 0.035
neuron projection development GO:0031175 106 0.034
Zebrafish Mouse Rat Fly
negative regulation of cell death GO:0060548 345 0.034
Mouse
response to growth factor GO:0070848 205 0.034
regulation of response to external stimulus GO:0032101 222 0.034
Mouse
regulation of cell cycle process GO:0010564 266 0.034
segmentation GO:0035282 4 0.034
Fly
regulation of transferase activity GO:0051338 355 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
Mouse
digestive system development GO:0055123 75 0.034
Zebrafish Worm
limbic system development GO:0021761 3 0.034
cellular response to growth factor stimulus GO:0071363 197 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
anterior posterior axis specification GO:0009948 2 0.033
Fly
cellular macromolecule catabolic process GO:0044265 380 0.033
behavior GO:0007610 112 0.033
response to biotic stimulus GO:0009607 276 0.032
covalent chromatin modification GO:0016569 254 0.032
bmp signaling pathway involved in heart development GO:0061312 3 0.032
regeneration GO:0031099 4 0.032
Rat
forebrain generation of neurons GO:0021872 3 0.032
membrane organization GO:0061024 292 0.031
cell projection morphogenesis GO:0048858 129 0.031
Zebrafish Mouse Fly
cellular chemical homeostasis GO:0055082 180 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.031
reproductive process GO:0022414 106 0.031
Worm
intracellular protein transport GO:0006886 270 0.030
protein processing GO:0016485 226 0.030
heart morphogenesis GO:0003007 48 0.030
regulation of intracellular transport GO:0032386 195 0.030
negative regulation of locomotion GO:0040013 118 0.030
tube development GO:0035295 125 0.030
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
adult locomotory behavior GO:0008344 1 0.030
response to hormone GO:0009725 175 0.030
Rat
peripheral nervous system development GO:0007422 2 0.030
Zebrafish Mouse
positive regulation of cell migration GO:0030335 172 0.030
regulation of neural precursor cell proliferation GO:2000177 4 0.030
protein catabolic process GO:0030163 325 0.030
protein maturation GO:0051604 233 0.030
forebrain regionalization GO:0021871 3 0.030
regulation of protein localization GO:0032880 296 0.030
regulation of cellular response to stress GO:0080135 244 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
regulation of protein transport GO:0051223 213 0.029
nucleotide catabolic process GO:0009166 408 0.029
cell part morphogenesis GO:0032990 137 0.029
Zebrafish Mouse Fly
negative regulation of cellular component movement GO:0051271 106 0.029
inner ear morphogenesis GO:0042472 4 0.029
digestive tract development GO:0048565 75 0.029
Worm
wnt signaling pathway GO:0016055 156 0.029
Mouse
negative regulation of phosphorylation GO:0042326 174 0.029
purine nucleotide catabolic process GO:0006195 405 0.029
cellular response to dna damage stimulus GO:0006974 379 0.029
tissue migration GO:0090130 119 0.028
cellular protein catabolic process GO:0044257 261 0.028
immune response GO:0006955 307 0.028
regulation of cell morphogenesis GO:0022604 153 0.028
defense response GO:0006952 315 0.028
Mouse
protein localization to organelle GO:0033365 280 0.028
mitotic cell cycle process GO:1903047 286 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
mapk cascade GO:0000165 288 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.028
cell growth GO:0016049 160 0.028
Zebrafish
embryonic epithelial tube formation GO:0001838 4 0.028
cell fate commitment involved in pattern specification GO:0060581 1 0.028
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
Mouse
cerebellum development GO:0021549 2 0.027
ameboidal type cell migration GO:0001667 135 0.027
Mouse
spinal cord dorsal ventral patterning GO:0021513 2 0.027
mesenchymal cell development GO:0014031 50 0.027
Mouse
nitrogen compound transport GO:0071705 191 0.027
Rat
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
neuron development GO:0048666 113 0.027
Zebrafish Mouse Rat Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
dna repair GO:0006281 198 0.027
regulation of homeostatic process GO:0032844 121 0.027
retinal ganglion cell axon guidance GO:0031290 2 0.026
Mouse
negative regulation of cell proliferation GO:0008285 228 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
regulation of protein kinase activity GO:0045859 289 0.026
positive regulation of cell death GO:0010942 263 0.026
regulation of secretion GO:0051046 194 0.026
Rat
dephosphorylation GO:0016311 209 0.026
organophosphate catabolic process GO:0046434 430 0.026
ion transmembrane transport GO:0034220 338 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.026
forebrain neuron differentiation GO:0021879 3 0.026
regulation of mapk cascade GO:0043408 262 0.026
regulation of cellular component biogenesis GO:0044087 281 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
sensory organ development GO:0007423 52 0.025
Human Fly
response to other organism GO:0051707 261 0.025
urogenital system development GO:0001655 65 0.025
positive regulation of cell development GO:0010720 92 0.025
positive regulation of catabolic process GO:0009896 310 0.025
response to cytokine GO:0034097 232 0.025
tube morphogenesis GO:0035239 95 0.025
embryonic forelimb morphogenesis GO:0035115 4 0.025
purine containing compound catabolic process GO:0072523 411 0.025
negative regulation of cell migration GO:0030336 102 0.025
single organism cell adhesion GO:0098602 179 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
heart field specification GO:0003128 2 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
cellular metal ion homeostasis GO:0006875 146 0.024
histone modification GO:0016570 251 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.024
embryonic eye morphogenesis GO:0048048 2 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
vesicle mediated transport GO:0016192 371 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
epithelial cell migration GO:0010631 119 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
cytokine production GO:0001816 247 0.024
Mouse
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
t cell differentiation in thymus GO:0033077 4 0.023
embryo development GO:0009790 123 0.023
Mouse Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.023
regionalization GO:0003002 29 0.023
positive regulation of transferase activity GO:0051347 227 0.023
somitogenesis GO:0001756 2 0.023
single organism reproductive process GO:0044702 98 0.023
Worm
protein targeting GO:0006605 187 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
tissue regeneration GO:0042246 3 0.023
cellular ion homeostasis GO:0006873 168 0.023
aortic valve development GO:0003176 3 0.023
multi organism cellular process GO:0044764 156 0.023
pattern specification process GO:0007389 43 0.023
nucleocytoplasmic transport GO:0006913 176 0.022
regulation of cell adhesion GO:0030155 166 0.022
nucleoside catabolic process GO:0009164 408 0.022
regulation of secretion by cell GO:1903530 177 0.022
Rat
ribonucleotide catabolic process GO:0009261 405 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
endomembrane system organization GO:0010256 196 0.022
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.022
salivary gland morphogenesis GO:0007435 4 0.022
response to decreased oxygen levels GO:0036293 96 0.022
leukocyte differentiation GO:0002521 98 0.022
response to inorganic substance GO:0010035 127 0.022
blastocyst development GO:0001824 3 0.022
mating GO:0007618 1 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
positive regulation of cell cycle GO:0045787 140 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.022
cellular lipid metabolic process GO:0044255 303 0.022
regulation of nervous system development GO:0051960 88 0.022
Mouse
endocrine system development GO:0035270 26 0.022
Zebrafish Mouse
negative regulation of cell cycle GO:0045786 193 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
gland development GO:0048732 48 0.021
Mouse Fly
negative regulation of protein modification process GO:0031400 200 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
regulation of cell growth GO:0001558 135 0.021
amide transport GO:0042886 76 0.021
Rat
glycosyl compound catabolic process GO:1901658 413 0.021
nuclear transport GO:0051169 179 0.021
hair follicle morphogenesis GO:0031069 2 0.021
neural tube formation GO:0001841 3 0.021
epithelium migration GO:0090132 119 0.021
anterior posterior axis specification embryo GO:0008595 2 0.021
Fly
positive regulation of hydrolase activity GO:0051345 331 0.021
regulation of establishment of protein localization GO:0070201 242 0.021
response to hypoxia GO:0001666 96 0.021
regulation of methylation dependent chromatin silencing GO:0090308 3 0.021
muscle structure development GO:0061061 98 0.021
Zebrafish Mouse Fly
epidermis morphogenesis GO:0048730 3 0.021
neural tube patterning GO:0021532 2 0.021
positive regulation of programmed cell death GO:0043068 249 0.021
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
regulation of myeloid cell differentiation GO:0045637 81 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
regulation of ion transport GO:0043269 189 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
multicellular organismal response to stress GO:0033555 1 0.020
actin cytoskeleton organization GO:0030036 207 0.020
hindlimb morphogenesis GO:0035137 2 0.020
circadian behavior GO:0048512 2 0.020
neural crest cell development GO:0014032 3 0.020
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 2 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
establishment of protein localization to organelle GO:0072594 172 0.020
associative learning GO:0008306 1 0.020
blastoderm segmentation GO:0007350 2 0.020
Fly
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
oocyte development GO:0048599 1 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
cation homeostasis GO:0055080 189 0.020
endodermal cell fate specification GO:0001714 4 0.020
regulation of growth GO:0040008 165 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
metal ion homeostasis GO:0055065 169 0.020
carbohydrate metabolic process GO:0005975 207 0.019
response to wounding GO:0009611 168 0.019
Mouse Rat
anatomical structure homeostasis GO:0060249 100 0.019
Fly
negative regulation of cell growth GO:0030308 83 0.019
regulation of protein maturation GO:1903317 150 0.019
oocyte differentiation GO:0009994 2 0.019
rhythmic behavior GO:0007622 2 0.019
innate immune response GO:0045087 178 0.019
neuroblast proliferation GO:0007405 4 0.019
wound healing GO:0042060 115 0.019
protein ubiquitination GO:0016567 314 0.019
regulation of cytokine production GO:0001817 232 0.019
Mouse
apoptotic signaling pathway GO:0097190 268 0.019
memory GO:0007613 3 0.019
ras protein signal transduction GO:0007265 73 0.019
metal ion transport GO:0030001 272 0.019
regulation of proteolysis GO:0030162 293 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
response to oxygen levels GO:0070482 100 0.019
positive regulation of protein transport GO:0051222 135 0.019
negative regulation of cell development GO:0010721 48 0.019
Mouse
cell division GO:0051301 168 0.019
endodermal cell fate commitment GO:0001711 4 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
embryonic camera type eye morphogenesis GO:0048596 2 0.019
prostate gland morphogenesis GO:0060512 1 0.019
compound eye development GO:0048749 1 0.019
cellular response to organic cyclic compound GO:0071407 127 0.018
Rat
cation transport GO:0006812 331 0.018
cell activation GO:0001775 213 0.018
forebrain dorsal ventral pattern formation GO:0021798 1 0.018
oxidation reduction process GO:0055114 396 0.018
regulation of dna metabolic process GO:0051052 153 0.018
myeloid leukocyte differentiation GO:0002573 60 0.018
negative regulation of protein processing GO:0010955 142 0.018
actin mediated cell contraction GO:0070252 12 0.018
spermatid differentiation GO:0048515 4 0.018
regulation of lipid metabolic process GO:0019216 96 0.018
regulation of protein processing GO:0070613 150 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
purine containing compound biosynthetic process GO:0072522 88 0.018
negative regulation of transport GO:0051051 176 0.018
viral process GO:0016032 146 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
response to nitrogen compound GO:1901698 184 0.018
leukocyte migration GO:0050900 107 0.018
negative regulation of protein maturation GO:1903318 142 0.018
microtubule based process GO:0007017 210 0.018
response to steroid hormone GO:0048545 80 0.018
Rat
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.018
neurological system process GO:0050877 163 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
cellular response to hormone stimulus GO:0032870 125 0.018
Rat
interspecies interaction between organisms GO:0044419 156 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
response to organonitrogen compound GO:0010243 156 0.018
maintenance of location GO:0051235 112 0.018
leukocyte activation GO:0045321 164 0.018
midgut development GO:0007494 1 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
cellular cation homeostasis GO:0030003 163 0.018
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.018
negative regulation of cell motility GO:2000146 104 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
tripartite regional subdivision GO:0007351 2 0.017
Fly
single organism carbohydrate metabolic process GO:0044723 193 0.017
inorganic ion transmembrane transport GO:0098660 231 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
anion transport GO:0006820 161 0.017
response to bacterium GO:0009617 144 0.017
intracellular receptor signaling pathway GO:0030522 104 0.017
Rat
secondary heart field specification GO:0003139 2 0.017
sensory perception of smell GO:0007608 2 0.017
renal system development GO:0072001 63 0.017
response to drug GO:0042493 81 0.017
organophosphate biosynthetic process GO:0090407 163 0.017
fatty acid metabolic process GO:0006631 115 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.017
Fly
mesenchymal cell differentiation GO:0048762 52 0.017
Mouse
cell substrate adhesion GO:0031589 132 0.017
positive regulation of kinase activity GO:0033674 204 0.017
tissue homeostasis GO:0001894 63 0.017
Fly
neuromuscular junction development GO:0007528 3 0.017
skin development GO:0043588 76 0.017
response to radiation GO:0009314 151 0.017
rho protein signal transduction GO:0007266 26 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
Mouse
regulation of stem cell differentiation GO:2000736 56 0.017
thymus development GO:0048538 3 0.016
multicellular organismal homeostasis GO:0048871 67 0.016
Fly
cardiac right ventricle morphogenesis GO:0003215 3 0.016
Mouse
g protein coupled receptor signaling pathway GO:0007186 207 0.016
primary neural tube formation GO:0014020 3 0.016
negative regulation of growth GO:0045926 97 0.016
protein localization to membrane GO:0072657 160 0.016
regulation of binding GO:0051098 111 0.016
Mouse Rat
response to axon injury GO:0048678 1 0.016
Rat
regulation of angiogenesis GO:0045765 92 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 3 0.016
prostate gland development GO:0030850 3 0.016
embryonic camera type eye formation GO:0060900 2 0.016
regulation of body fluid levels GO:0050878 99 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
stem cell division GO:0017145 2 0.016
detection of stimulus GO:0051606 85 0.016
negative regulation of proteolysis GO:0045861 132 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
receptor metabolic process GO:0043112 81 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.016
Mouse
regulation of neuron differentiation GO:0045664 70 0.016
Mouse
hippocampus development GO:0021766 1 0.016
optic nerve development GO:0021554 2 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
actin filament based movement GO:0030048 17 0.015
ion homeostasis GO:0050801 230 0.015
monovalent inorganic cation transport GO:0015672 128 0.015
regulation of transmission of nerve impulse GO:0051969 2 0.015
endodermal mesodermal cell signaling GO:0003133 3 0.015
male genitalia development GO:0030539 1 0.015
androgen biosynthetic process GO:0006702 3 0.015
organ induction GO:0001759 4 0.015
cell cycle phase transition GO:0044770 173 0.015
spermatid development GO:0007286 4 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
regulation of multi organism process GO:0043900 157 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
hormone secretion GO:0046879 65 0.015
Rat
cellular response to cytokine stimulus GO:0071345 181 0.015
cellular response to lipid GO:0071396 127 0.015
Rat
negative regulation of organelle organization GO:0010639 126 0.015
tube closure GO:0060606 3 0.015
neural tube closure GO:0001843 3 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
gtp catabolic process GO:0006184 237 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
Mouse
atp metabolic process GO:0046034 176 0.015
sensory perception of pain GO:0019233 4 0.015
mesenchyme development GO:0060485 59 0.015
Mouse
negative regulation of immune system process GO:0002683 136 0.015
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.015

ISL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.048
musculoskeletal system disease DOID:17 223 0.027
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
sensory system disease DOID:0050155 203 0.023
nervous system disease DOID:863 431 0.023
central nervous system disease DOID:331 186 0.020
bone disease DOID:0080001 88 0.018
connective tissue disease DOID:65 109 0.018
inherited metabolic disorder DOID:655 242 0.018
acquired metabolic disease DOID:0060158 58 0.017
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016