Homo sapiens

0 known processes

ISL2

ISL LIM homeobox 2

(Aliases: FLJ10160)

ISL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate commitment GO:0048663 2 0.103
Zebrafish Mouse
regulation of cell differentiation GO:0045595 393 0.083
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.077
post embryonic development GO:0009791 2 0.075
Worm
spinal cord development GO:0021510 4 0.064
Mouse
amine metabolic process GO:0009308 44 0.062
negative regulation of multicellular organismal process GO:0051241 317 0.061
Mouse
cellular ketone metabolic process GO:0042180 80 0.061
regulation of cellular ketone metabolic process GO:0010565 50 0.061
cellular amino acid metabolic process GO:0006520 116 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.060
organ formation GO:0048645 3 0.060
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.059
cell development GO:0048468 328 0.059
Zebrafish Mouse Fly
cellular amine metabolic process GO:0044106 41 0.057
anatomical structure formation involved in morphogenesis GO:0048646 284 0.057
Human
specification of organ identity GO:0010092 3 0.057
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.054
cardiac cell fate determination GO:0060913 3 0.052
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
cell fate determination GO:0001709 3 0.049
Human Fly
cell morphogenesis GO:0000902 296 0.049
Zebrafish Mouse Fly
circulatory system development GO:0072359 262 0.049
Human Fly
organ morphogenesis GO:0009887 147 0.048
Human Worm Fly
cellular component morphogenesis GO:0032989 314 0.047
Zebrafish Mouse Fly
cell differentiation in spinal cord GO:0021515 1 0.046
Mouse
nervous system development GO:0007399 293 0.046
Zebrafish Mouse Fly
regulation of locomotion GO:0040012 329 0.044
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
regulation of cell development GO:0060284 161 0.041
Mouse
epithelium development GO:0060429 227 0.041
Fly
system process GO:0003008 349 0.041
Worm
regulation of cell motility GO:2000145 299 0.041
positive regulation of cell proliferation GO:0008284 301 0.040
extraocular skeletal muscle development GO:0002074 1 0.040
regulation of cellular component movement GO:0051270 334 0.040
negative regulation of cell death GO:0060548 345 0.040
enzyme linked receptor protein signaling pathway GO:0007167 303 0.039
Fly
multicellular organismal aging GO:0010259 3 0.039
cardiovascular system development GO:0072358 262 0.038
Human Fly
determination of adult lifespan GO:0008340 2 0.037
segmentation GO:0035282 4 0.037
Fly
negative regulation of cell differentiation GO:0045596 171 0.037
Mouse
positive regulation of developmental process GO:0051094 314 0.037
negative regulation of programmed cell death GO:0043069 321 0.036
hindbrain development GO:0030902 3 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
negative regulation of apoptotic process GO:0043066 316 0.036
neurogenesis GO:0022008 169 0.034
Zebrafish Mouse Fly
biological adhesion GO:0022610 331 0.034
positive regulation of hydrolase activity GO:0051345 331 0.034
motor neuron axon guidance GO:0008045 2 0.034
Fly
cell adhesion GO:0007155 325 0.034
regulation of cell cycle GO:0051726 393 0.033
negative regulation of developmental process GO:0051093 247 0.033
Mouse
regulation of cell migration GO:0030334 289 0.033
forebrain regionalization GO:0021871 3 0.033
female gamete generation GO:0007292 2 0.032
immune response GO:0006955 307 0.032
epithelial cell differentiation GO:0030855 141 0.032
forelimb morphogenesis GO:0035136 4 0.032
forebrain generation of neurons GO:0021872 3 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
negative regulation of cell proliferation GO:0008285 228 0.031
positive regulation of cell differentiation GO:0045597 211 0.030
oogenesis GO:0048477 2 0.030
generation of neurons GO:0048699 152 0.030
Zebrafish Mouse Fly
small gtpase mediated signal transduction GO:0007264 78 0.030
locomotory behavior GO:0007626 1 0.030
cytoplasmic transport GO:0016482 379 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
nerve development GO:0021675 4 0.030
glycosyl compound catabolic process GO:1901658 413 0.029
cell projection organization GO:0030030 252 0.029
Zebrafish Mouse Fly
negative regulation of protein metabolic process GO:0051248 391 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
mitotic cell cycle GO:0000278 326 0.029
regulation of proteolysis GO:0030162 293 0.029
response to oxygen containing compound GO:1901700 369 0.029
peripheral nervous system development GO:0007422 2 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
neuron differentiation GO:0030182 138 0.028
Zebrafish Mouse Fly
lipid metabolic process GO:0006629 381 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.028
ras protein signal transduction GO:0007265 73 0.028
purine containing compound catabolic process GO:0072523 411 0.028
pituitary gland development GO:0021983 2 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
morphogenesis of embryonic epithelium GO:0016331 4 0.028
Fly
positive regulation of transport GO:0051050 336 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
positive regulation of cellular component organization GO:0051130 376 0.027
cranial nerve development GO:0021545 4 0.027
positive regulation of programmed cell death GO:0043068 249 0.027
embryonic forelimb morphogenesis GO:0035115 4 0.027
nucleoside catabolic process GO:0009164 408 0.027
positive regulation of cell death GO:0010942 263 0.027
purine nucleotide catabolic process GO:0006195 405 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
regulation of transferase activity GO:0051338 355 0.027
ribonucleotide catabolic process GO:0009261 405 0.027
response to abiotic stimulus GO:0009628 336 0.027
ribonucleoside catabolic process GO:0042454 406 0.027
regulation of protein localization GO:0032880 296 0.026
vesicle mediated transport GO:0016192 371 0.026
positive regulation of apoptotic process GO:0043065 246 0.026
single organism cellular localization GO:1902580 332 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.026
nucleotide catabolic process GO:0009166 408 0.026
organophosphate catabolic process GO:0046434 430 0.026
cytokine production GO:0001816 247 0.026
actin filament based process GO:0030029 224 0.025
purine ribonucleotide catabolic process GO:0009154 404 0.025
negative regulation of phosphate metabolic process GO:0045936 267 0.025
defense response GO:0006952 315 0.025
inner ear morphogenesis GO:0042472 4 0.025
vasculature development GO:0001944 181 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.025
neuromuscular junction development GO:0007528 3 0.025
response to lipid GO:0033993 206 0.025
cell morphogenesis involved in differentiation GO:0000904 144 0.025
Zebrafish Mouse Fly
regulation of response to external stimulus GO:0032101 222 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.024
regeneration GO:0031099 4 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
protein catabolic process GO:0030163 325 0.024
regulation of kinase activity GO:0043549 314 0.024
cellular response to oxygen containing compound GO:1901701 276 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
blastoderm segmentation GO:0007350 2 0.024
Fly
membrane organization GO:0061024 292 0.024
immune system development GO:0002520 195 0.023
Fly
regulation of cytokine production GO:0001817 232 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
Fly
brain development GO:0007420 97 0.023
regulation of protein kinase activity GO:0045859 289 0.023
positive regulation of immune system process GO:0002684 283 0.023
regulation of protein transport GO:0051223 213 0.023
secretion by cell GO:0032940 226 0.023
apoptotic signaling pathway GO:0097190 268 0.023
single organism membrane organization GO:0044802 268 0.022
cellular lipid metabolic process GO:0044255 303 0.022
negative regulation of locomotion GO:0040013 118 0.022
anterior posterior axis specification GO:0009948 2 0.022
Fly
signal transduction by phosphorylation GO:0023014 297 0.022
cardiac right ventricle morphogenesis GO:0003215 3 0.022
muscle structure development GO:0061061 98 0.022
Fly
central nervous system development GO:0007417 123 0.022
Mouse
regulation of secretion GO:0051046 194 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
protein localization to organelle GO:0033365 280 0.022
chromatin organization GO:0006325 351 0.022
secretion GO:0046903 254 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
metencephalon development GO:0022037 2 0.022
regulation of cell morphogenesis GO:0022604 153 0.022
embryonic epithelial tube formation GO:0001838 4 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
regulation of neural precursor cell proliferation GO:2000177 4 0.022
heart formation GO:0060914 2 0.021
Human
protein ubiquitination GO:0016567 314 0.021
regulation of establishment of protein localization GO:0070201 242 0.021
negative regulation of cell cycle GO:0045786 193 0.021
mapk cascade GO:0000165 288 0.021
protein modification by small protein conjugation GO:0032446 342 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
positive regulation of catabolic process GO:0009896 310 0.021
blood vessel development GO:0001568 172 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
chemical homeostasis GO:0048878 306 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
protein maturation GO:0051604 233 0.021
regulation of cellular response to stress GO:0080135 244 0.020
ventral spinal cord development GO:0021517 1 0.020
Mouse
limbic system development GO:0021761 3 0.020
head development GO:0060322 108 0.020
Worm
regulation of cell cycle process GO:0010564 266 0.020
intracellular protein transport GO:0006886 270 0.020
response to external biotic stimulus GO:0043207 261 0.020
hemopoiesis GO:0030097 180 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
forebrain neuron differentiation GO:0021879 3 0.020
positive regulation of neural precursor cell proliferation GO:2000179 2 0.020
regulation of peptidase activity GO:0052547 180 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
compound eye development GO:0048749 1 0.019
negative regulation of cell migration GO:0030336 102 0.019
growth GO:0040007 202 0.019
Zebrafish
adult locomotory behavior GO:0008344 1 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
cellular protein catabolic process GO:0044257 261 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
rho protein signal transduction GO:0007266 26 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
response to growth factor GO:0070848 205 0.019
mitotic cell cycle process GO:1903047 286 0.019
chromatin modification GO:0016568 298 0.019
menstrual cycle phase GO:0022601 2 0.019
response to other organism GO:0051707 261 0.019
regulation of mapk cascade GO:0043408 262 0.019
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
gtp metabolic process GO:0046039 239 0.019
oxidation reduction process GO:0055114 396 0.019
thymus development GO:0048538 3 0.019
response to organic cyclic compound GO:0014070 204 0.019
response to hormone GO:0009725 175 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.018
neuroblast proliferation GO:0007405 4 0.018
innate immune response GO:0045087 178 0.018
response to wounding GO:0009611 168 0.018
memory GO:0007613 3 0.018
protein processing GO:0016485 226 0.018
cellular homeostasis GO:0019725 196 0.018
positive regulation of cytokine production GO:0001819 167 0.018
cation transport GO:0006812 331 0.018
stem cell differentiation GO:0048863 93 0.018
maintenance of location GO:0051235 112 0.018
pharynx development GO:0060465 1 0.018
Worm
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
outflow tract septum morphogenesis GO:0003148 4 0.018
oocyte development GO:0048599 1 0.018
wnt signaling pathway GO:0016055 156 0.018
blood vessel morphogenesis GO:0048514 162 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
regulation of secretion by cell GO:1903530 177 0.018
positive regulation of organelle organization GO:0010638 195 0.018
dephosphorylation GO:0016311 209 0.018
cell activation GO:0001775 213 0.018
tube development GO:0035295 125 0.018
Worm
single organism cell adhesion GO:0098602 179 0.018
gtp catabolic process GO:0006184 237 0.018
oocyte differentiation GO:0009994 2 0.017
cation homeostasis GO:0055080 189 0.017
regulation of cell adhesion GO:0030155 166 0.017
positive regulation of transferase activity GO:0051347 227 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
regulation of intracellular transport GO:0032386 195 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.017
neurological system process GO:0050877 163 0.017
transmembrane transport GO:0055085 399 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
neuron development GO:0048666 113 0.017
Zebrafish Mouse Fly
histone modification GO:0016570 251 0.017
nitrogen compound transport GO:0071705 191 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
ion transmembrane transport GO:0034220 338 0.017
regulation of hormone levels GO:0010817 125 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
cell part morphogenesis GO:0032990 137 0.017
Zebrafish Mouse Fly
neurotransmitter secretion GO:0007269 4 0.017
negative regulation of protein modification process GO:0031400 200 0.017
covalent chromatin modification GO:0016569 254 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
glial cell migration GO:0008347 4 0.017
protein targeting GO:0006605 187 0.017
neural crest cell development GO:0014032 3 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
metal ion transport GO:0030001 272 0.017
taxis GO:0042330 157 0.017
Zebrafish Mouse Fly
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.017
regulation of nervous system development GO:0051960 88 0.017
Mouse
tripartite regional subdivision GO:0007351 2 0.017
Fly
regulation of cytoskeleton organization GO:0051493 177 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
ion homeostasis GO:0050801 230 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
lipid biosynthetic process GO:0008610 177 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
Fly
response to biotic stimulus GO:0009607 276 0.016
cell growth GO:0016049 160 0.016
Zebrafish
cell projection morphogenesis GO:0048858 129 0.016
Zebrafish Mouse Fly
endocrine system development GO:0035270 26 0.016
somitogenesis GO:0001756 2 0.016
actin cytoskeleton organization GO:0030036 207 0.016
regulation of immune response GO:0050776 201 0.016
spermatid differentiation GO:0048515 4 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
modification dependent macromolecule catabolic process GO:0043632 212 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
organelle assembly GO:0070925 176 0.016
regulation of neurogenesis GO:0050767 82 0.016
Mouse
divalent metal ion transport GO:0070838 152 0.016
response to fungus GO:0009620 4 0.015
angiogenesis GO:0001525 147 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
positive regulation of cellular component movement GO:0051272 181 0.015
endomembrane system organization GO:0010256 196 0.015
chemotaxis GO:0006935 157 0.015
Zebrafish Mouse Fly
cation transmembrane transport GO:0098655 238 0.015
tissue morphogenesis GO:0048729 96 0.015
Fly
hindlimb morphogenesis GO:0035137 2 0.015
sex determination GO:0007530 3 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
positive regulation of cell development GO:0010720 92 0.015
positive regulation of proteolysis GO:0045862 142 0.015
regulation of multi organism process GO:0043900 157 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
nucleocytoplasmic transport GO:0006913 176 0.015
neural tube formation GO:0001841 3 0.015
carbohydrate metabolic process GO:0005975 207 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
microtubule based process GO:0007017 210 0.015
positive regulation of hormone biosynthetic process GO:0046886 4 0.015
regulation of homeostatic process GO:0032844 121 0.015
embryonic camera type eye development GO:0031076 2 0.015
metal ion homeostasis GO:0055065 169 0.015
response to cytokine GO:0034097 232 0.015
positive regulation of cell migration GO:0030335 172 0.015
skeletal system development GO:0001501 79 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
cell fate commitment involved in pattern specification GO:0060581 1 0.015
Fly
morphogenesis of a polarized epithelium GO:0001738 3 0.015
positive regulation of locomotion GO:0040017 186 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
nuclear transport GO:0051169 179 0.015
rhythmic behavior GO:0007622 2 0.015
cerebellum development GO:0021549 2 0.015
cellular chemical homeostasis GO:0055082 180 0.015
negative regulation of transport GO:0051051 176 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
small molecule biosynthetic process GO:0044283 157 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
positive regulation of kinase activity GO:0033674 204 0.015
cellular response to lipid GO:0071396 127 0.014
epidermis morphogenesis GO:0048730 3 0.014
neuron projection development GO:0031175 106 0.014
Zebrafish Mouse Fly
positive regulation of cell motility GO:2000147 177 0.014
regulation of growth GO:0040008 165 0.014
negative regulation of cell motility GO:2000146 104 0.014
regulation of neuron differentiation GO:0045664 70 0.014
Mouse
negative regulation of phosphorylation GO:0042326 174 0.014
cell division GO:0051301 168 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
visual behavior GO:0007632 2 0.014
cellular cation homeostasis GO:0030003 163 0.014
embryo development GO:0009790 123 0.014
Fly
mesenchyme development GO:0060485 59 0.014
cellular ion homeostasis GO:0006873 168 0.014
associative learning GO:0008306 1 0.014
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.014
cartilage condensation GO:0001502 1 0.014
regulation of protein catabolic process GO:0042176 155 0.014
epithelial cell proliferation GO:0050673 128 0.014
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.014
rna processing GO:0006396 255 0.014
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.014
positive regulation of immune response GO:0050778 159 0.014
salivary gland morphogenesis GO:0007435 4 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
cellular protein complex assembly GO:0043623 188 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of gtpase activity GO:0043087 180 0.014
dna repair GO:0006281 198 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
sequestering of metal ion GO:0051238 24 0.014
response to axon injury GO:0048678 1 0.014
cellular metal ion homeostasis GO:0006875 146 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
positive regulation of protein transport GO:0051222 135 0.014
immune effector process GO:0002252 159 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
globus pallidus development GO:0021759 1 0.014
spermatid development GO:0007286 4 0.014
ossification GO:0001503 121 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.013
post embryonic organ development GO:0048569 1 0.013
cell substrate adhesion GO:0031589 132 0.013
protein localization to membrane GO:0072657 160 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
Fly
myoblast fusion GO:0007520 1 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
cell cell signaling GO:0007267 155 0.013
positive regulation of aldosterone metabolic process GO:0032346 2 0.013
circadian behavior GO:0048512 2 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
developmental programmed cell death GO:0010623 3 0.013
protein oligomerization GO:0051259 173 0.013
primary neural tube formation GO:0014020 3 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
tissue regeneration GO:0042246 3 0.013
male genitalia development GO:0030539 1 0.013
positive regulation of cell cycle GO:0045787 140 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
somatic stem cell maintenance GO:0035019 4 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
positive regulation of secretion GO:0051047 116 0.013
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.013
negative regulation of immune system process GO:0002683 136 0.013
muscle cell fate commitment GO:0042693 4 0.013
Fly
divalent inorganic cation transport GO:0072511 158 0.013
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.013
negative regulation of gliogenesis GO:0014014 3 0.013
regulation of protein processing GO:0070613 150 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
oxidative stress induced premature senescence GO:0090403 3 0.013
negative regulation of protein processing GO:0010955 142 0.013
regulation of binding GO:0051098 111 0.013
regulation of cell growth GO:0001558 135 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
myeloid cell differentiation GO:0030099 117 0.013
tube closure GO:0060606 3 0.013
reproductive process GO:0022414 106 0.013
Worm
mesenchymal cell differentiation GO:0048762 52 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
heart field specification GO:0003128 2 0.013
Human
embryonic viscerocranium morphogenesis GO:0048703 1 0.013
defense response to fungus GO:0050832 4 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
sequestering of calcium ion GO:0051208 17 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of defense response GO:0031347 154 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
negative regulation of protein maturation GO:1903318 142 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
endocytosis GO:0006897 159 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.013
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.013
regulation of vasculature development GO:1901342 97 0.013
establishment of planar polarity GO:0001736 3 0.013
response to radiation GO:0009314 151 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
sensory perception of pain GO:0019233 4 0.012
regulation of organ formation GO:0003156 4 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
cell proliferation in forebrain GO:0021846 1 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
embryonic morphogenesis GO:0048598 85 0.012
Fly
organophosphate biosynthetic process GO:0090407 163 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
startle response GO:0001964 3 0.012
regulation of stem cell differentiation GO:2000736 56 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of neuroblast proliferation GO:1902692 3 0.012
endodermal cell fate commitment GO:0001711 4 0.012
positive regulation of cardioblast differentiation GO:0051891 2 0.012
stem cell division GO:0017145 2 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
regulation of response to wounding GO:1903034 101 0.012
mesenchymal cell development GO:0014031 50 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
protein localization to nucleus GO:0034504 136 0.012
behavior GO:0007610 112 0.012
actin filament based movement GO:0030048 17 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
regulation of epithelial cell proliferation GO:0050678 113 0.012
muscle tissue development GO:0060537 62 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
stem cell development GO:0048864 69 0.012
regulation of cardioblast differentiation GO:0051890 4 0.012

ISL2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.036
disease of metabolism DOID:0014667 295 0.027
sensory system disease DOID:0050155 203 0.025
nervous system disease DOID:863 431 0.025
connective tissue disease DOID:65 109 0.021
bone disease DOID:0080001 88 0.021
inherited metabolic disorder DOID:655 242 0.020
eye and adnexa disease DOID:1492 150 0.020
eye disease DOID:5614 149 0.020
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.019
organ system cancer DOID:0050686 164 0.017
central nervous system disease DOID:331 186 0.016
cardiovascular system disease DOID:1287 106 0.015
muscular disease DOID:0080000 114 0.013
muscle tissue disease DOID:66 113 0.013
heart disease DOID:114 68 0.013
immune system disease DOID:2914 155 0.012
retinal disease DOID:5679 118 0.012