Homo sapiens

31 known processes

PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

(Aliases: DKFZp547K1610,FLJ20093,MYT1)

PKMYT1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 116 0.517
dna conformation change GO:0071103 113 0.429
double strand break repair GO:0006302 101 0.400
mitotic sister chromatid cohesion GO:0007064 12 0.349
ubiquitin dependent protein catabolic process GO:0006511 206 0.241
centrosome organization GO:0051297 58 0.209
dna repair GO:0006281 198 0.205
modification dependent macromolecule catabolic process GO:0043632 212 0.204
cellular response to dna damage stimulus GO:0006974 379 0.188
Fly
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 2 0.171
cell cycle g2 m phase transition GO:0044839 43 0.152
Fly
organelle fission GO:0048285 149 0.139
Fly
protein ubiquitination GO:0016567 314 0.138
post embryonic development GO:0009791 2 0.132
Worm
g2 m transition of mitotic cell cycle GO:0000086 41 0.132
Fly
sister chromatid segregation GO:0000819 54 0.126
female gamete generation GO:0007292 2 0.123
Worm Fly
dna recombination GO:0006310 77 0.115
mitotic nuclear division GO:0007067 119 0.113
negative regulation of cell size GO:0045792 3 0.111
negative regulation of cell cycle GO:0045786 193 0.109
Fly
regulation of cell cycle GO:0051726 393 0.108
Fly
dephosphorylation GO:0016311 209 0.103
protein modification by small protein conjugation GO:0032446 342 0.101
chromosome segregation GO:0007059 114 0.087
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.086
covalent chromatin modification GO:0016569 254 0.086
cellular protein catabolic process GO:0044257 261 0.083
positive regulation of dna metabolic process GO:0051054 73 0.081
meiosis i GO:0007127 4 0.081
mitotic cell cycle phase transition GO:0044772 162 0.081
Fly
regulation of dna metabolic process GO:0051052 153 0.080
regulation of chromosome organization GO:0033044 103 0.079
dna biosynthetic process GO:0071897 40 0.073
regulation of cell diameter GO:0060305 1 0.073
determination of adult lifespan GO:0008340 2 0.073
cellular macromolecule catabolic process GO:0044265 380 0.071
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.071
protein dephosphorylation GO:0006470 81 0.071
positive regulation of cell proliferation GO:0008284 301 0.069
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.067
protein catabolic process GO:0030163 325 0.067
regulation of cell cycle process GO:0010564 266 0.067
Fly
immune response GO:0006955 307 0.066
nucleotide catabolic process GO:0009166 408 0.065
anatomical structure formation involved in morphogenesis GO:0048646 284 0.065
Fly
organophosphate catabolic process GO:0046434 430 0.065
positive regulation of mitotic cell cycle GO:0045931 60 0.064
purine containing compound catabolic process GO:0072523 411 0.064
centrosome cycle GO:0007098 32 0.063
vesicle mediated transport GO:0016192 371 0.063
Worm
purine nucleoside catabolic process GO:0006152 398 0.061
ribonucleoside triphosphate catabolic process GO:0009203 391 0.061
cell development GO:0048468 328 0.059
Worm Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.058
mitotic cell cycle process GO:1903047 286 0.057
Fly
positive regulation of response to dna damage stimulus GO:2001022 43 0.057
cell cycle g1 s phase transition GO:0044843 80 0.057
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.057
ribonucleoside triphosphate metabolic process GO:0009199 412 0.055
regulation of spindle organization GO:0090224 10 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
multicellular organismal aging GO:0010259 3 0.054
muscle structure development GO:0061061 98 0.053
modification dependent protein catabolic process GO:0019941 209 0.051
negative regulation of phosphorus metabolic process GO:0010563 267 0.051
negative regulation of mitotic cell cycle GO:0045930 102 0.051
Fly
mitotic sister chromatid segregation GO:0000070 53 0.051
mitotic cell cycle GO:0000278 326 0.050
Fly
positive regulation of cell cycle GO:0045787 140 0.050
nuclear division GO:0000280 128 0.050
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.049
dna packaging GO:0006323 77 0.049
purine nucleoside monophosphate metabolic process GO:0009126 186 0.048
chromatin organization GO:0006325 351 0.048
positive regulation of exit from mitosis GO:0031536 2 0.048
nucleoside phosphate catabolic process GO:1901292 412 0.048
proteasomal protein catabolic process GO:0010498 176 0.047
chromatin modification GO:0016568 298 0.047
cellular response to abiotic stimulus GO:0071214 117 0.047
regulation of chromosome segregation GO:0051983 44 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.046
reactive oxygen species metabolic process GO:0072593 75 0.044
recombinational repair GO:0000725 50 0.044
negative regulation of apoptotic process GO:0043066 316 0.044
g1 s transition of mitotic cell cycle GO:0000082 78 0.043
rna processing GO:0006396 255 0.043
regulation of mitotic sister chromatid segregation GO:0033047 27 0.042
microtubule organizing center organization GO:0031023 62 0.041
dna duplex unwinding GO:0032508 30 0.039
positive regulation of hydrolase activity GO:0051345 331 0.039
regulation of cell cycle phase transition GO:1901987 126 0.038
Fly
dna damage checkpoint GO:0000077 68 0.038
Fly
positive regulation of catabolic process GO:0009896 310 0.038
regulation of centrosome duplication GO:0010824 14 0.038
negative regulation of cell cycle phase transition GO:1901988 89 0.037
Fly
negative regulation of programmed cell death GO:0043069 321 0.037
positive regulation of cell cycle process GO:0090068 106 0.037
double strand break repair via homologous recombination GO:0000724 50 0.036
purine ribonucleotide catabolic process GO:0009154 404 0.036
response to abiotic stimulus GO:0009628 336 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
response to oxygen containing compound GO:1901700 369 0.036
cellular amine metabolic process GO:0044106 41 0.035
ribonucleoside catabolic process GO:0042454 406 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
cell cycle phase transition GO:0044770 173 0.034
Fly
positive regulation of developmental process GO:0051094 314 0.034
positive regulation of organelle organization GO:0010638 195 0.034
mitotic sister chromatid separation GO:0051306 18 0.033
regulation of dna replication GO:0006275 68 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.033
dna geometric change GO:0032392 32 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.032
positive regulation of dna replication GO:0045740 35 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.031
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.031
telomere maintenance GO:0000723 32 0.030
atp catabolic process GO:0006200 157 0.030
non recombinational repair GO:0000726 14 0.030
regulation of meiotic cell cycle GO:0051445 4 0.030
negative regulation of cell death GO:0060548 345 0.030
small gtpase mediated signal transduction GO:0007264 78 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
regulation of cellular amine metabolic process GO:0033238 11 0.029
regulation of mitotic cell cycle GO:0007346 189 0.029
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.029
dna dependent dna replication GO:0006261 44 0.029
regulation of transferase activity GO:0051338 355 0.028
nucleoside catabolic process GO:0009164 408 0.028
neutral lipid catabolic process GO:0046461 12 0.028
response to radiation GO:0009314 151 0.028
regulation of cellular component size GO:0032535 82 0.028
Fly
oocyte differentiation GO:0009994 2 0.027
Worm
golgi organization GO:0007030 38 0.027
dna catabolic process GO:0006308 49 0.027
male meiosis GO:0007140 1 0.027
Fly
regulation of proteolysis GO:0030162 293 0.027
positive regulation of chromosome organization GO:2001252 41 0.027
endocytosis GO:0006897 159 0.026
Worm
reproductive process GO:0022414 106 0.025
Worm Fly
histone modification GO:0016570 251 0.025
protein localization to organelle GO:0033365 280 0.024
histone serine phosphorylation GO:0035404 4 0.024
membrane organization GO:0061024 292 0.024
regulation of kinase activity GO:0043549 314 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
mapk cascade GO:0000165 288 0.022
cell fate commitment GO:0045165 27 0.022
regulation of cellular response to stress GO:0080135 244 0.022
metaphase anaphase transition of cell cycle GO:0044784 21 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
epithelial cell differentiation GO:0030855 141 0.022
cellular response to oxygen containing compound GO:1901701 276 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
Fly
cell activation GO:0001775 213 0.021
regulation of dephosphorylation GO:0035303 96 0.021
cyclin catabolic process GO:0008054 6 0.021
organelle assembly GO:0070925 176 0.021
cellular component disassembly GO:0022411 92 0.020
cell projection organization GO:0030030 252 0.020
cell morphogenesis GO:0000902 296 0.020
methylation GO:0032259 106 0.020
protein processing GO:0016485 226 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
ras protein signal transduction GO:0007265 73 0.020
oocyte development GO:0048599 1 0.019
Worm
mitotic spindle elongation GO:0000022 4 0.019
nucleus organization GO:0006997 28 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
negative regulation of proteolysis GO:0045861 132 0.019
atp metabolic process GO:0046034 176 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
positive regulation of immune system process GO:0002684 283 0.019
nervous system development GO:0007399 293 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
response to light stimulus GO:0009416 87 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
cell cycle checkpoint GO:0000075 117 0.018
Fly
spindle checkpoint GO:0031577 26 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
regulation of proteasomal protein catabolic process GO:0061136 87 0.018
microtubule based process GO:0007017 210 0.018
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.018
regulation of mitosis GO:0007088 63 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
amine metabolic process GO:0009308 44 0.018
actin filament based process GO:0030029 224 0.018
regulation of protein dephosphorylation GO:0035304 18 0.018
nucleosome assembly GO:0006334 50 0.018
oogenesis GO:0048477 2 0.018
Worm Fly
neuron projection development GO:0031175 106 0.017
spindle organization GO:0007051 53 0.017
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.017
cellular homeostasis GO:0019725 196 0.017
neuron development GO:0048666 113 0.017
regulation of binding GO:0051098 111 0.017
response to reactive oxygen species GO:0000302 61 0.017
cardiovascular system development GO:0072358 262 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.016
cellular component morphogenesis GO:0032989 314 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
mitotic cell cycle checkpoint GO:0007093 68 0.016
Fly
epithelium development GO:0060429 227 0.016
apoptotic signaling pathway GO:0097190 268 0.016
cytoplasmic transport GO:0016482 379 0.016
regulation of growth GO:0040008 165 0.016
negative regulation of developmental process GO:0051093 247 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
negative regulation of protein maturation GO:1903318 142 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.016
lung cell differentiation GO:0060479 1 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
regulation of protein catabolic process GO:0042176 155 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
developmental process involved in reproduction GO:0003006 66 0.016
Worm Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
protein acylation GO:0043543 138 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
chromatin assembly or disassembly GO:0006333 78 0.015
regulation of anatomical structure size GO:0090066 101 0.015
Fly
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
defense response GO:0006952 315 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.015
negative regulation of protein modification process GO:0031400 200 0.015
negative regulation of cytoskeleton organization GO:0051494 45 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
Fly
cellular response to radiation GO:0071478 65 0.015
humoral immune response GO:0006959 49 0.014
response to biotic stimulus GO:0009607 276 0.014
endomembrane system organization GO:0010256 196 0.014
cell growth GO:0016049 160 0.014
exit from mitosis GO:0010458 10 0.014
response to oxidative stress GO:0006979 121 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
positive regulation of t helper cell differentiation GO:0045624 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
response to external biotic stimulus GO:0043207 261 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
glomerular epithelial cell development GO:0072310 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
mrna processing GO:0006397 133 0.014
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.014
regulation of chromatin modification GO:1903308 51 0.014
myosin filament assembly GO:0031034 2 0.014
regulation of endodeoxyribonuclease activity GO:0032071 3 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
t helper cell differentiation GO:0042093 4 0.014
positive regulation of t cell activation GO:0050870 54 0.013
central nervous system development GO:0007417 123 0.013
oocyte maturation GO:0001556 1 0.013
Worm
histone ubiquitination GO:0016574 31 0.013
regulation of dna repair GO:0006282 47 0.013
locomotory behavior GO:0007626 1 0.013
single organism reproductive process GO:0044702 98 0.013
Worm Fly
chromatin assembly GO:0031497 61 0.013
cell part morphogenesis GO:0032990 137 0.013
cellular response to uv GO:0034644 32 0.013
cell cell signaling GO:0007267 155 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
macromolecule methylation GO:0043414 97 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
regulation of histone modification GO:0031056 47 0.013
peptidyl lysine modification GO:0018205 144 0.013
regulation of protein maturation GO:1903317 150 0.013
sister chromatid cohesion GO:0007062 24 0.013
chromatin remodeling GO:0006338 55 0.012
immune system development GO:0002520 195 0.012
regulation of intracellular transport GO:0032386 195 0.012
cell projection morphogenesis GO:0048858 129 0.012
peptidyl serine modification GO:0018209 106 0.012
protein oligomerization GO:0051259 173 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
protein complex disassembly GO:0043241 52 0.012
protein dna complex subunit organization GO:0071824 80 0.012
lung epithelial cell differentiation GO:0060487 1 0.012
secretion by cell GO:0032940 226 0.012
regulation of mapk cascade GO:0043408 262 0.012
chromosome separation GO:0051304 23 0.012
immune effector process GO:0002252 159 0.012
regulation of fibroblast proliferation GO:0048145 32 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
positive regulation of mitosis GO:0045840 25 0.012
cell cell signaling involved in cell fate commitment GO:0045168 5 0.012
response to uv GO:0009411 73 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
cellular response to fatty acid GO:0071398 8 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
digestive system development GO:0055123 75 0.012
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.012
secretion GO:0046903 254 0.011
cellular response to reactive oxygen species GO:0034614 50 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
positive regulation of chromatin modification GO:1903310 30 0.011
reproduction GO:0000003 63 0.011
Worm Fly
cellular ketone metabolic process GO:0042180 80 0.011
response to hypoxia GO:0001666 96 0.011
single organism membrane organization GO:0044802 268 0.011
head development GO:0060322 108 0.011
spindle assembly GO:0051225 29 0.011
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
blood vessel development GO:0001568 172 0.011
macromolecular complex disassembly GO:0032984 60 0.011
generation of neurons GO:0048699 152 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
regulation of cell differentiation GO:0045595 393 0.011
regulation of protein kinase activity GO:0045859 289 0.011
protein polyubiquitination GO:0000209 110 0.011
dna integrity checkpoint GO:0031570 71 0.011
Fly
negative regulation of transport GO:0051051 176 0.011
mitotic cytokinesis GO:0000281 19 0.010
ion transmembrane transport GO:0034220 338 0.010
neurogenesis GO:0022008 169 0.010
mrna metabolic process GO:0016071 175 0.010
meiotic chromosome segregation GO:0045132 4 0.010
stress activated mapk cascade GO:0051403 93 0.010
negative regulation of transferase activity GO:0051348 124 0.010
rna splicing GO:0008380 131 0.010
regulation of homeostatic process GO:0032844 121 0.010
cilium assembly GO:0042384 63 0.010
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
spermatid differentiation GO:0048515 4 0.010
positive regulation of histone modification GO:0031058 29 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010

PKMYT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 55 0.340
bone disease DOID:0080001 88 0.340
musculoskeletal system disease DOID:17 223 0.340
connective tissue disease DOID:65 109 0.340
dysostosis DOID:1934 22 0.054
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.025
integumentary system disease DOID:16 43 0.023
thoracic cancer DOID:5093 21 0.010