Homo sapiens

80 known processes

ZNF148

zinc finger protein 148

(Aliases: DKFZp686L18248,BFCOL1,BERF-1,ZFP148,pHZ-52,HT-BETA,ZBP-89)

ZNF148 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.801
Rat
chromatin modification GO:0016568 298 0.682
histone modification GO:0016570 251 0.563
histone acetylation GO:0016573 93 0.487
locomotory behavior GO:0007626 1 0.388
determination of adult lifespan GO:0008340 2 0.360
protein acetylation GO:0006473 116 0.331
chromatin organization GO:0006325 351 0.320
negative regulation of cell cycle GO:0045786 193 0.315
cellular response to dna damage stimulus GO:0006974 379 0.311
regulation of histone deacetylase activity GO:1901725 3 0.295
regulation of mitotic cell cycle GO:0007346 189 0.292
peptidyl lysine modification GO:0018205 144 0.195
regulation of protein localization GO:0032880 296 0.195
covalent chromatin modification GO:0016569 254 0.190
multicellular organismal aging GO:0010259 3 0.189
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.163
hard palate development GO:0060022 1 0.157
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.153
skeletal system development GO:0001501 79 0.150
forelimb morphogenesis GO:0035136 4 0.146
protein maturation GO:0051604 233 0.138
regulation of cell cycle GO:0051726 393 0.128
mitotic cell cycle phase transition GO:0044772 162 0.125
positive regulation of transport GO:0051050 336 0.125
cellular macromolecule catabolic process GO:0044265 380 0.118
mitotic cell cycle process GO:1903047 286 0.112
cardiovascular system development GO:0072358 262 0.112
myeloid cell differentiation GO:0030099 117 0.111
histone demethylation GO:0016577 15 0.108
chemical homeostasis GO:0048878 306 0.108
circulatory system development GO:0072359 262 0.108
cell cycle phase transition GO:0044770 173 0.106
circadian behavior GO:0048512 2 0.104
regulation of locomotion GO:0040012 329 0.100
regulation of cellular component biogenesis GO:0044087 281 0.095
mitotic cell cycle GO:0000278 326 0.093
androgen biosynthetic process GO:0006702 3 0.092
vasculature development GO:0001944 181 0.091
intracellular estrogen receptor signaling pathway GO:0030520 23 0.087
signal transduction by phosphorylation GO:0023014 297 0.086
segmentation GO:0035282 4 0.085
internal peptidyl lysine acetylation GO:0018393 97 0.083
negative regulation of phosphate metabolic process GO:0045936 267 0.083
negative regulation of protein metabolic process GO:0051248 391 0.083
histone h3 acetylation GO:0043966 45 0.082
regulation of transferase activity GO:0051338 355 0.082
response to sterol GO:0036314 14 0.081
cellular amino acid metabolic process GO:0006520 116 0.080
regulation of protein transport GO:0051223 213 0.075
long term memory GO:0007616 2 0.074
lipid metabolic process GO:0006629 381 0.072
cell morphogenesis GO:0000902 296 0.072
growth GO:0040007 202 0.071
cell cycle checkpoint GO:0000075 117 0.071
response to other organism GO:0051707 261 0.070
vesicle mediated transport GO:0016192 371 0.070
protein ubiquitination GO:0016567 314 0.068
positive regulation of developmental process GO:0051094 314 0.065
negative regulation of mitotic cell cycle GO:0045930 102 0.064
blood vessel development GO:0001568 172 0.064
regulation of protein maturation GO:1903317 150 0.063
anatomical structure formation involved in morphogenesis GO:0048646 284 0.063
regulation of cell differentiation GO:0045595 393 0.061
positive regulation of catabolic process GO:0009896 310 0.061
negative regulation of phosphorylation GO:0042326 174 0.061
negative regulation of cellular protein metabolic process GO:0032269 353 0.061
histone h3 k4 demethylation trimethyl h3 k4 specific GO:0034721 1 0.059
embryonic placenta development GO:0001892 1 0.058
regulation of innate immune response GO:0045088 97 0.058
regionalization GO:0003002 29 0.056
response to organic cyclic compound GO:0014070 204 0.055
metal ion transport GO:0030001 272 0.054
notch signaling pathway GO:0007219 31 0.054
negative regulation of phosphorus metabolic process GO:0010563 267 0.054
negative regulation of protein processing GO:0010955 142 0.053
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.053
epithelium development GO:0060429 227 0.052
protein catabolic process GO:0030163 325 0.052
otic vesicle development GO:0071599 1 0.051
mitotic nuclear division GO:0007067 119 0.051
regulation of anatomical structure morphogenesis GO:0022603 286 0.050
negative regulation of cellular component organization GO:0051129 235 0.049
negative regulation of proteolysis GO:0045861 132 0.048
cellular ketone metabolic process GO:0042180 80 0.048
cell development GO:0048468 328 0.048
histone deacetylation GO:0016575 32 0.048
peptidyl lysine acetylation GO:0018394 101 0.048
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.048
proteasomal protein catabolic process GO:0010498 176 0.047
heart development GO:0007507 95 0.047
nuclear export GO:0051168 69 0.046
mapk cascade GO:0000165 288 0.046
ubiquitin dependent protein catabolic process GO:0006511 206 0.046
ameboidal type cell migration GO:0001667 135 0.045
modification dependent protein catabolic process GO:0019941 209 0.045
hematopoietic or lymphoid organ development GO:0048534 186 0.045
Zebrafish
regulation of homeostatic process GO:0032844 121 0.044
epithelial cell migration GO:0010631 119 0.044
negative regulation of hydrolase activity GO:0051346 182 0.043
microtubule cytoskeleton organization GO:0000226 176 0.043
cell division GO:0051301 168 0.042
blood vessel morphogenesis GO:0048514 162 0.041
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.041
purine nucleoside catabolic process GO:0006152 398 0.041
developmental growth GO:0048589 48 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.041
behavior GO:0007610 112 0.041
dna damage checkpoint GO:0000077 68 0.040
endodermal cell fate specification GO:0001714 4 0.040
response to biotic stimulus GO:0009607 276 0.039
organ morphogenesis GO:0009887 147 0.039
peptidyl threonine phosphorylation GO:0018107 41 0.039
methylation GO:0032259 106 0.039
generation of neurons GO:0048699 152 0.038
chordate embryonic development GO:0043009 34 0.038
cellular response to oxygen containing compound GO:1901701 276 0.038
regulation of response to external stimulus GO:0032101 222 0.038
protein processing GO:0016485 226 0.038
embryo development GO:0009790 123 0.037
fat cell differentiation GO:0045444 32 0.037
tissue morphogenesis GO:0048729 96 0.037
regulation of defense response GO:0031347 154 0.037
rhythmic behavior GO:0007622 2 0.036
dna integrity checkpoint GO:0031570 71 0.036
neuromuscular junction development GO:0007528 3 0.036
nuclear transport GO:0051169 179 0.036
nucleotide catabolic process GO:0009166 408 0.036
regulation of mitotic cell cycle phase transition GO:1901990 118 0.036
epithelium migration GO:0090132 119 0.035
cation transport GO:0006812 331 0.035
regulation of cell cycle process GO:0010564 266 0.035
regulation of developmental growth GO:0048638 30 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
positive regulation of immune system process GO:0002684 283 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.033
embryonic forelimb morphogenesis GO:0035115 4 0.033
cellular protein catabolic process GO:0044257 261 0.033
leukocyte activation GO:0045321 164 0.033
response to radiation GO:0009314 151 0.033
negative regulation of multicellular organismal process GO:0051241 317 0.033
response to lipid GO:0033993 206 0.032
nucleosome organization GO:0034728 66 0.032
apoptotic signaling pathway GO:0097190 268 0.032
mitotic dna integrity checkpoint GO:0044774 30 0.032
regulation of protein processing GO:0070613 150 0.031
sensory perception of sound GO:0007605 37 0.031
cerebral cortex radially oriented cell migration GO:0021799 1 0.031
tube development GO:0035295 125 0.031
regulation of growth GO:0040008 165 0.031
post embryonic development GO:0009791 2 0.031
negative regulation of protein maturation GO:1903318 142 0.031
purine nucleotide catabolic process GO:0006195 405 0.030
nucleocytoplasmic transport GO:0006913 176 0.030
regulation of myeloid cell differentiation GO:0045637 81 0.030
regulation of proteolysis GO:0030162 293 0.030
regulation of mapk cascade GO:0043408 262 0.030
tissue migration GO:0090130 119 0.030
regulation of cellular response to stress GO:0080135 244 0.029
regulation of dephosphorylation GO:0035303 96 0.029
mitotic cell cycle checkpoint GO:0007093 68 0.029
brain development GO:0007420 97 0.029
organelle assembly GO:0070925 176 0.029
regulation of cell motility GO:2000145 299 0.029
negative regulation of cell cycle phase transition GO:1901988 89 0.028
modification dependent macromolecule catabolic process GO:0043632 212 0.028
dephosphorylation GO:0016311 209 0.028
cellular response to organic cyclic compound GO:0071407 127 0.028
male sex differentiation GO:0046661 25 0.028
regulation of intracellular transport GO:0032386 195 0.028
amine metabolic process GO:0009308 44 0.028
defense response GO:0006952 315 0.028
cytokine production GO:0001816 247 0.028
intrinsic apoptotic signaling pathway GO:0097193 127 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
positive regulation of innate immune response GO:0045089 79 0.027
purine containing compound catabolic process GO:0072523 411 0.027
pituitary gland development GO:0021983 2 0.027
lung alveolus development GO:0048286 4 0.027
cell projection organization GO:0030030 252 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
taxis GO:0042330 157 0.027
positive regulation of wnt signaling pathway GO:0030177 54 0.027
positive regulation of cell cycle GO:0045787 140 0.027
cell morphogenesis involved in differentiation GO:0000904 144 0.027
macromolecule methylation GO:0043414 97 0.027
spindle assembly GO:0051225 29 0.026
protein acylation GO:0043543 138 0.026
negative regulation of transport GO:0051051 176 0.026
response to hormone GO:0009725 175 0.026
response to metal ion GO:0010038 84 0.026
internal protein amino acid acetylation GO:0006475 101 0.026
mitochondrion organization GO:0007005 156 0.025
single organism membrane organization GO:0044802 268 0.025
negative regulation of immune system process GO:0002683 136 0.025
negative regulation of cell death GO:0060548 345 0.025
negative regulation of catabolic process GO:0009895 104 0.025
jak stat cascade GO:0007259 46 0.025
regulation of cytoplasmic transport GO:1903649 149 0.024
negative regulation of protein catabolic process GO:0042177 59 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of cellular component movement GO:0051270 334 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
posttranscriptional regulation of gene expression GO:0010608 213 0.024
negative regulation of cell cycle process GO:0010948 121 0.023
response to inorganic substance GO:0010035 127 0.023
organelle fission GO:0048285 149 0.023
cellular component morphogenesis GO:0032989 314 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
blastoderm segmentation GO:0007350 2 0.023
regulation of cell cycle phase transition GO:1901987 126 0.023
histone lysine demethylation GO:0070076 14 0.023
chemotaxis GO:0006935 157 0.022
dna templated transcription initiation GO:0006352 35 0.022
oogenesis GO:0048477 2 0.022
memory GO:0007613 3 0.022
cellular response to lipid GO:0071396 127 0.022
positive regulation of gliogenesis GO:0014015 4 0.022
embryonic limb morphogenesis GO:0030326 9 0.022
nuclear import GO:0051170 106 0.022
histone h3 k4 demethylation GO:0034720 4 0.022
protein polyubiquitination GO:0000209 110 0.022
hemopoiesis GO:0030097 180 0.021
Zebrafish
reproductive process GO:0022414 106 0.021
Mouse
response to external biotic stimulus GO:0043207 261 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
negative regulation of protein modification process GO:0031400 200 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
hindbrain development GO:0030902 3 0.021
regulation of gene expression epigenetic GO:0040029 73 0.021
regulation of lipid metabolic process GO:0019216 96 0.020
transmembrane transport GO:0055085 399 0.020
neurological system process GO:0050877 163 0.020
positive regulation of cell cycle process GO:0090068 106 0.020
regulation of nucleocytoplasmic transport GO:0046822 98 0.020
cellular response to abiotic stimulus GO:0071214 117 0.020
multicellular organismal homeostasis GO:0048871 67 0.020
muscle organ development GO:0007517 56 0.020
regulation of intracellular protein transport GO:0033157 123 0.020
response to endoplasmic reticulum stress GO:0034976 49 0.020
cytokinesis GO:0000910 96 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
immune response activating signal transduction GO:0002757 90 0.020
regulation of cell development GO:0060284 161 0.020
single organism cellular localization GO:1902580 332 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
sensory perception of mechanical stimulus GO:0050954 37 0.019
digestive tract development GO:0048565 75 0.019
rna localization GO:0006403 41 0.019
response to oxygen containing compound GO:1901700 369 0.019
bone development GO:0060348 26 0.018
immune system development GO:0002520 195 0.018
Zebrafish
ribonucleotide catabolic process GO:0009261 405 0.018
reproductive structure development GO:0048608 55 0.018
secretion GO:0046903 254 0.018
regulation of response to wounding GO:1903034 101 0.018
histone lysine methylation GO:0034968 50 0.018
macromolecule deacylation GO:0098732 41 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
protein targeting to nucleus GO:0044744 104 0.018
myeloid leukocyte differentiation GO:0002573 60 0.017
angiogenesis GO:0001525 147 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.017
nuclear division GO:0000280 128 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
regulation of cell division GO:0051302 116 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
response to growth factor GO:0070848 205 0.017
aging GO:0007568 66 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
cellular response to endogenous stimulus GO:0071495 336 0.017
lymphocyte activation GO:0046649 133 0.017
single organism reproductive process GO:0044702 98 0.017
Mouse
cellular lipid metabolic process GO:0044255 303 0.017
photoreceptor cell differentiation GO:0046530 2 0.017
heart morphogenesis GO:0003007 48 0.016
nervous system development GO:0007399 293 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
single organism nuclear import GO:1902593 104 0.016
protein deacylation GO:0035601 39 0.016
lipid biosynthetic process GO:0008610 177 0.016
actin filament based process GO:0030029 224 0.016
regulation of protein catabolic process GO:0042176 155 0.016
spermatid differentiation GO:0048515 4 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
female gamete generation GO:0007292 2 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
cytoplasmic transport GO:0016482 379 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
protein deacetylation GO:0006476 38 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
embryonic organ development GO:0048568 36 0.016
negative regulation of phosphatase activity GO:0010923 61 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
epithelial tube morphogenesis GO:0060562 38 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
protein targeting GO:0006605 187 0.015
oxidation reduction process GO:0055114 396 0.015
response to wounding GO:0009611 168 0.015
nucleobase containing compound transport GO:0015931 51 0.015
positive regulation of organelle organization GO:0010638 195 0.015
regulation of gtpase activity GO:0043087 180 0.015
rho protein signal transduction GO:0007266 26 0.015
head development GO:0060322 108 0.015
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
neuron differentiation GO:0030182 138 0.014
stress activated mapk cascade GO:0051403 93 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
regulation of protein deacetylation GO:0090311 12 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
chromatin remodeling GO:0006338 55 0.014
protein localization to organelle GO:0033365 280 0.014
muscle structure development GO:0061061 98 0.014
leukocyte differentiation GO:0002521 98 0.014
immune effector process GO:0002252 159 0.014
positive regulation of kinase activity GO:0033674 204 0.014
pattern specification process GO:0007389 43 0.014
inner ear morphogenesis GO:0042472 4 0.014
gene silencing GO:0016458 49 0.014
response to abiotic stimulus GO:0009628 336 0.014
protein k48 linked ubiquitination GO:0070936 38 0.014
response to nitrogen compound GO:1901698 184 0.014
organelle localization GO:0051640 84 0.014
regulation of leukocyte activation GO:0002694 115 0.014
regulation of dna metabolic process GO:0051052 153 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
positive regulation of leukocyte differentiation GO:1902107 37 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
sister chromatid cohesion GO:0007062 24 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.013
regulation of muscle organ development GO:0048634 27 0.013
regulation of protein complex assembly GO:0043254 147 0.013
regulation of phosphatase activity GO:0010921 81 0.013
organic acid transport GO:0015849 65 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
morphogenesis of an epithelium GO:0002009 60 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
negative regulation of jak stat cascade GO:0046426 4 0.013
divalent metal ion transport GO:0070838 152 0.013
protein k48 linked deubiquitination GO:0071108 19 0.013
protein import into nucleus GO:0006606 104 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
nitrogen compound transport GO:0071705 191 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
homeostasis of number of cells GO:0048872 40 0.012
ribonucleoprotein complex subunit organization GO:0071826 81 0.012
regulation of leukocyte differentiation GO:1902105 61 0.012
regulation of cytokine production GO:0001817 232 0.012
ossification GO:0001503 121 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
multicellular organism reproduction GO:0032504 42 0.012
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.012
cellular homeostasis GO:0019725 196 0.012
cell projection morphogenesis GO:0048858 129 0.012
cell type specific apoptotic process GO:0097285 125 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.012
autophagy GO:0006914 88 0.012
organophosphate catabolic process GO:0046434 430 0.012
regulation of multicellular organism growth GO:0040014 8 0.012
immune response regulating signaling pathway GO:0002764 97 0.012
dna dependent dna replication GO:0006261 44 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
reproductive system development GO:0061458 56 0.012
tube morphogenesis GO:0035239 95 0.012
cell migration involved in gastrulation GO:0042074 1 0.012
negative regulation of histone modification GO:0031057 19 0.012
cellular response to biotic stimulus GO:0071216 71 0.012
gtp catabolic process GO:0006184 237 0.012
central nervous system development GO:0007417 123 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
negative regulation of neuron apoptotic process GO:0043524 23 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
cytoskeleton dependent intracellular transport GO:0030705 21 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
positive regulation of interleukin 4 production GO:0032753 3 0.011
positive regulation of cytoplasmic transport GO:1903651 82 0.011
regulation of nuclear division GO:0051783 65 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
negative regulation of dephosphorylation GO:0035305 63 0.011
lymphocyte homeostasis GO:0002260 4 0.011
central nervous system neuron axonogenesis GO:0021955 3 0.011
cellular senescence GO:0090398 34 0.011
nucleus localization GO:0051647 1 0.011
determination of dorsal ventral asymmetry GO:0048262 4 0.011
neural tube formation GO:0001841 3 0.011
regulation of fat cell differentiation GO:0045598 23 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
regulation of jnk cascade GO:0046328 73 0.011
myosin filament assembly GO:0031034 2 0.011
developmental process involved in reproduction GO:0003006 66 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.011
epidermis morphogenesis GO:0048730 3 0.011
cell growth GO:0016049 160 0.011
innate immune response GO:0045087 178 0.011
cerebellum development GO:0021549 2 0.011
myosin filament organization GO:0031033 2 0.011
alpha beta t cell differentiation GO:0046632 7 0.011
lipid homeostasis GO:0055088 39 0.011
positive regulation of protein complex assembly GO:0031334 86 0.010
double strand break repair GO:0006302 101 0.010
negative regulation of organelle organization GO:0010639 126 0.010
ceramide transport GO:0035627 3 0.010
endocytosis GO:0006897 159 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
energy derivation by oxidation of organic compounds GO:0015980 43 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
response to glucagon GO:0033762 1 0.010
carbohydrate metabolic process GO:0005975 207 0.010
interspecies interaction between organisms GO:0044419 156 0.010
positive regulation of cellular amine metabolic process GO:0033240 7 0.010
cilium morphogenesis GO:0060271 75 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
regulation of ossification GO:0030278 58 0.010
regulation of jak stat cascade GO:0046425 44 0.010
regulation of chromatin modification GO:1903308 51 0.010
ion homeostasis GO:0050801 230 0.010
atp catabolic process GO:0006200 157 0.010

ZNF148 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.030
disease of cellular proliferation DOID:14566 174 0.030
organ system cancer DOID:0050686 164 0.012
gastrointestinal system cancer DOID:3119 52 0.011