Homo sapiens

2 known processes

PFAS

phosphoribosylformylglycinamidine synthase

(Aliases: FGARAT,FGAMS,KIAA0361,PURL)

PFAS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.254
cellular amino acid metabolic process GO:0006520 116 0.204
vesicle mediated transport GO:0016192 371 0.151
ncrna metabolic process GO:0034660 108 0.145
rna phosphodiester bond hydrolysis GO:0090501 35 0.113
trna metabolic process GO:0006399 35 0.087
microtubule based process GO:0007017 210 0.076
cellular macromolecular complex assembly GO:0034622 324 0.067
circulatory system development GO:0072359 262 0.054
endocytosis GO:0006897 159 0.050
single organism cellular localization GO:1902580 332 0.042
female gamete generation GO:0007292 2 0.040
nucleotide biosynthetic process GO:0009165 109 0.037
Yeast
determination of adult lifespan GO:0008340 2 0.037
alpha amino acid metabolic process GO:1901605 72 0.036
cellular ketone metabolic process GO:0042180 80 0.035
negative regulation of programmed cell death GO:0043069 321 0.033
negative regulation of cell death GO:0060548 345 0.032
embryo development GO:0009790 123 0.031
rrna metabolic process GO:0016072 40 0.030
cytoplasmic transport GO:0016482 379 0.030
multicellular organismal aging GO:0010259 3 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.030
coenzyme metabolic process GO:0006732 65 0.030
intracellular mrna localization GO:0008298 1 0.028
mrna metabolic process GO:0016071 175 0.027
ribonucleoprotein complex biogenesis GO:0022613 116 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
nucleobase biosynthetic process GO:0046112 4 0.026
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.025
translation GO:0006412 132 0.025
mitochondrial translation GO:0032543 17 0.024
organonitrogen compound biosynthetic process GO:1901566 200 0.024
Yeast
ribosome biogenesis GO:0042254 48 0.024
anterior posterior axis specification GO:0009948 2 0.024
actin filament based process GO:0030029 224 0.024
cellular protein complex assembly GO:0043623 188 0.024
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
trna aminoacylation for protein translation GO:0006418 8 0.021
ncrna processing GO:0034470 83 0.021
cofactor metabolic process GO:0051186 87 0.020
rna splicing GO:0008380 131 0.020
protein localization to nucleus GO:0034504 136 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
organelle assembly GO:0070925 176 0.020
cellular modified amino acid metabolic process GO:0006575 64 0.019
amine metabolic process GO:0009308 44 0.019
myosin filament assembly GO:0031034 2 0.019
intracellular protein transport GO:0006886 270 0.019
glutamine family amino acid metabolic process GO:0009064 17 0.019
rna processing GO:0006396 255 0.018
dna replication GO:0006260 116 0.018
protein localization to organelle GO:0033365 280 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
organ morphogenesis GO:0009887 147 0.017
regulation of protein localization GO:0032880 296 0.017
regulation of transferase activity GO:0051338 355 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
reproductive process GO:0022414 106 0.016
oocyte differentiation GO:0009994 2 0.016
positive regulation of transport GO:0051050 336 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
reproduction GO:0000003 63 0.016
cellular amine metabolic process GO:0044106 41 0.016
maintenance of location GO:0051235 112 0.016
mitotic cell cycle GO:0000278 326 0.015
maturation of lsu rrna GO:0000470 3 0.015
amino acid activation GO:0043038 12 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
defense response to other organism GO:0098542 129 0.015
chromatin organization GO:0006325 351 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
pharynx development GO:0060465 1 0.015
nervous system development GO:0007399 293 0.015
compound eye development GO:0048749 1 0.014
cell cell signaling GO:0007267 155 0.014
single organism reproductive process GO:0044702 98 0.014
regulation of locomotion GO:0040012 329 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
nuclear transport GO:0051169 179 0.014
oogenesis GO:0048477 2 0.014
regulation of protein transport GO:0051223 213 0.014
chemical homeostasis GO:0048878 306 0.014
establishment of protein localization to organelle GO:0072594 172 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
protein import GO:0017038 130 0.013
cell activation GO:0001775 213 0.013
purine containing compound catabolic process GO:0072523 411 0.013
regulation of mrna metabolic process GO:1903311 53 0.012
regulation of cell growth GO:0001558 135 0.012
locomotory behavior GO:0007626 1 0.012
regulation of protein kinase activity GO:0045859 289 0.012
cardiovascular system development GO:0072358 262 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
mitotic cell cycle process GO:1903047 286 0.012
cell adhesion GO:0007155 325 0.012
segmentation GO:0035282 4 0.012
hindbrain development GO:0030902 3 0.012
ribose phosphate biosynthetic process GO:0046390 82 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
lymphocyte activation GO:0046649 133 0.012
maintenance of protein location GO:0045185 57 0.011
myosin filament organization GO:0031033 2 0.011
protein dna complex assembly GO:0065004 64 0.011
methylation GO:0032259 106 0.011
oocyte development GO:0048599 1 0.011
regulation of cellular response to stress GO:0080135 244 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
sterol homeostasis GO:0055092 28 0.011
cellular component morphogenesis GO:0032989 314 0.011
dna conformation change GO:0071103 113 0.011
central nervous system development GO:0007417 123 0.011
secretion by cell GO:0032940 226 0.011
protein import into nucleus GO:0006606 104 0.011
embryo development ending in birth or egg hatching GO:0009792 34 0.011
regeneration GO:0031099 4 0.011
tissue morphogenesis GO:0048729 96 0.011
blastocyst development GO:0001824 3 0.011
alpha amino acid catabolic process GO:1901606 26 0.011
maintenance of location in cell GO:0051651 62 0.011
protein alkylation GO:0008213 74 0.011
glutamine metabolic process GO:0006541 2 0.011
multi organism reproductive process GO:0044703 54 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.010
cell projection organization GO:0030030 252 0.010
single organism membrane organization GO:0044802 268 0.010
mitochondrial rna metabolic process GO:0000959 15 0.010
mrna splicing via spliceosome GO:0000398 89 0.010
biological adhesion GO:0022610 331 0.010
neurogenesis GO:0022008 169 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
negative regulation of protein modification process GO:0031400 200 0.010
cellular macromolecule catabolic process GO:0044265 380 0.010

PFAS disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.067
central nervous system disease DOID:331 186 0.033
nervous system disease DOID:863 431 0.033
inherited metabolic disorder DOID:655 242 0.018
neurodegenerative disease DOID:1289 102 0.010