Homo sapiens

259 known processes

SOD1

superoxide dismutase 1, soluble

(Aliases: homodimer,SOD,IPOA,ALS,ALS1)

SOD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to superoxide GO:0071451 6 0.997
protein oxidation GO:0018158 5 0.992
hydrogen peroxide metabolic process GO:0042743 20 0.933
cellular response to oxygen radical GO:0071450 6 0.923
ketone catabolic process GO:0042182 3 0.842
mitochondrion organization GO:0007005 156 0.841
hydrogen peroxide catabolic process GO:0042744 13 0.785
membrane hyperpolarization GO:0060081 1 0.783
response to oxygen radical GO:0000305 6 0.730
regulation of cellular response to oxidative stress GO:1900407 26 0.678
purine ribonucleoside metabolic process GO:0046128 437 0.654
negative regulation of cell death GO:0060548 345 0.648
oxidation reduction process GO:0055114 396 0.643
reactive oxygen species metabolic process GO:0072593 75 0.643
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.636
superoxide metabolic process GO:0006801 20 0.632
negative regulation of apoptotic process GO:0043066 316 0.623
nucleoside monophosphate metabolic process GO:0009123 191 0.621
alcohol metabolic process GO:0006066 114 0.616
peptidyl cysteine modification GO:0018198 9 0.616
cellular response to hydrogen peroxide GO:0070301 37 0.615
primary alcohol metabolic process GO:0034308 17 0.610
response to reactive oxygen species GO:0000302 61 0.609
amine metabolic process GO:0009308 44 0.608
response to oxidative stress GO:0006979 121 0.581
purine nucleoside triphosphate metabolic process GO:0009144 412 0.580
response to superoxide GO:0000303 6 0.580
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.578
trail activated apoptotic signaling pathway GO:0036462 4 0.553
negative regulation of programmed cell death GO:0043069 321 0.552
cellular response to oxidative stress GO:0034599 85 0.548
negative regulation of protein metabolic process GO:0051248 391 0.531
defense response GO:0006952 315 0.515
cellular amine metabolic process GO:0044106 41 0.508
negative regulation of peptidase activity GO:0010466 91 0.474
peptidyl cysteine oxidation GO:0018171 1 0.469
negative regulation of phosphate metabolic process GO:0045936 267 0.439
monocarboxylic acid metabolic process GO:0032787 185 0.438
negative regulation of hydrogen peroxide induced cell death GO:1903206 9 0.410
nucleotide catabolic process GO:0009166 408 0.408
response to oxygen containing compound GO:1901700 369 0.398
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.386
regulation of cellular amino acid metabolic process GO:0006521 6 0.384
dopamine biosynthetic process GO:0042416 4 0.383
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.381
cellular response to reactive oxygen species GO:0034614 50 0.375
purine ribonucleotide catabolic process GO:0009154 404 0.371
regulation of cellular amine metabolic process GO:0033238 11 0.363
ribonucleoside monophosphate metabolic process GO:0009161 187 0.362
cellular lipid metabolic process GO:0044255 303 0.354
cellular modified amino acid biosynthetic process GO:0042398 15 0.351
regulation of peptidase activity GO:0052547 180 0.350
purine ribonucleoside catabolic process GO:0046130 398 0.349
negative regulation of protein processing GO:0010955 142 0.348
multicellular organismal aging GO:0010259 3 0.331
Fly
cell cell signaling GO:0007267 155 0.330
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.325
negative regulation of cellular response to oxidative stress GO:1900408 18 0.319
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.310
purine nucleoside triphosphate catabolic process GO:0009146 392 0.306
cytoplasmic transport GO:0016482 379 0.299
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.292
negative regulation of oxidative stress induced cell death GO:1903202 17 0.291
negative regulation of endopeptidase activity GO:0010951 84 0.289
cell death in response to oxidative stress GO:0036473 29 0.288
regulation of endopeptidase activity GO:0052548 170 0.284
response to inorganic substance GO:0010035 127 0.284
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.281
negative regulation of cellular protein metabolic process GO:0032269 353 0.278
response to hydrogen peroxide GO:0042542 40 0.274
regulation of protein processing GO:0070613 150 0.271
cellular ketone metabolic process GO:0042180 80 0.271
protein folding GO:0006457 38 0.267
determination of adult lifespan GO:0008340 2 0.266
Fly
regulation of kinase activity GO:0043549 314 0.266
regulation of dna binding GO:0051101 37 0.265
positive regulation of cellular amine metabolic process GO:0033240 7 0.265
negative regulation of hydrolase activity GO:0051346 182 0.254
regulation of transporter activity GO:0032409 82 0.254
ribonucleoside triphosphate metabolic process GO:0009199 412 0.253
positive regulation of ion transport GO:0043270 87 0.251
small molecule catabolic process GO:0044282 92 0.251
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.238
negative regulation of protein maturation GO:1903318 142 0.233
negative regulation of phosphorus metabolic process GO:0010563 267 0.233
ribonucleoside monophosphate catabolic process GO:0009158 158 0.230
regulation of cysteine type endopeptidase activity GO:2000116 127 0.227
protein processing GO:0016485 226 0.225
organic acid biosynthetic process GO:0016053 97 0.223
negative regulation of proteolysis GO:0045861 132 0.221
atp metabolic process GO:0046034 176 0.218
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.215
heat acclimation GO:0010286 3 0.213
intracellular protein transport GO:0006886 270 0.212
regulation of protein maturation GO:1903317 150 0.212
regulation of cellular ketone metabolic process GO:0010565 50 0.211
carboxylic acid biosynthetic process GO:0046394 97 0.209
nucleoside phosphate catabolic process GO:1901292 412 0.208
positive regulation of binding GO:0051099 45 0.206
nitrogen compound transport GO:0071705 191 0.203
regulation of membrane potential GO:0042391 95 0.202
positive regulation of phosphorylation GO:0042327 394 0.198
cellular response to oxygen containing compound GO:1901701 276 0.195
protein localization to organelle GO:0033365 280 0.193
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.188
cellular amino acid biosynthetic process GO:0008652 30 0.185
alpha amino acid biosynthetic process GO:1901607 23 0.181
cell death in response to hydrogen peroxide GO:0036474 10 0.172
cellular macromolecule catabolic process GO:0044265 380 0.166
female gamete generation GO:0007292 2 0.164
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.162
regulation of mitochondrial membrane potential GO:0051881 23 0.161
organophosphate catabolic process GO:0046434 430 0.160
protein maturation GO:0051604 233 0.159
purine nucleoside monophosphate metabolic process GO:0009126 186 0.159
regulation of purine nucleotide metabolic process GO:1900542 264 0.158
positive regulation of protein phosphorylation GO:0001934 313 0.156
positive regulation of response to oxidative stress GO:1902884 7 0.152
regulation of protein localization to nucleus GO:1900180 85 0.152
regulation of nucleocytoplasmic transport GO:0046822 98 0.149
regulation of proteasomal protein catabolic process GO:0061136 87 0.148
positive regulation of cell proliferation GO:0008284 301 0.144
extrinsic apoptotic signaling pathway GO:0097191 119 0.141
small molecule biosynthetic process GO:0044283 157 0.141
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.139
regulation of nucleotide metabolic process GO:0006140 269 0.137
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 2 0.135
regulation of defense response GO:0031347 154 0.134
purine nucleotide catabolic process GO:0006195 405 0.134
regulation of proteolysis GO:0030162 293 0.133
cellular amino acid metabolic process GO:0006520 116 0.131
positive regulation of nucleotide metabolic process GO:0045981 230 0.130
organic hydroxy compound metabolic process GO:1901615 147 0.130
regulation of protein localization GO:0032880 296 0.129
protein ubiquitination GO:0016567 314 0.129
regulation of establishment of protein localization GO:0070201 242 0.127
locomotory behavior GO:0007626 1 0.123
protein modification by small protein conjugation GO:0032446 342 0.121
regulation of transmembrane transport GO:0034762 139 0.121
regulation of protein stability GO:0031647 87 0.120
negative regulation of response to oxidative stress GO:1902883 18 0.115
nucleoside monophosphate catabolic process GO:0009125 159 0.113
regulation of ion transport GO:0043269 189 0.110
regulation of androgen receptor activity GO:2000823 3 0.110
lipid metabolic process GO:0006629 381 0.105
mapk cascade GO:0000165 288 0.104
negative regulation of protein modification process GO:0031400 200 0.102
response to wounding GO:0009611 168 0.101
negative regulation of kinase activity GO:0033673 106 0.101
monovalent inorganic cation transport GO:0015672 128 0.100
aldehyde catabolic process GO:0046185 5 0.100
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.097
negative regulation of catalytic activity GO:0043086 335 0.097
inflammatory response GO:0006954 79 0.096
cellular modified amino acid metabolic process GO:0006575 64 0.096
regulation of multi organism process GO:0043900 157 0.095
positive regulation of nucleoside metabolic process GO:0045979 186 0.095
regulation of response to external stimulus GO:0032101 222 0.094
apoptotic signaling pathway GO:0097190 268 0.094
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.093
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.092
positive regulation of transmembrane transport GO:0034764 41 0.090
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.090
purine containing compound catabolic process GO:0072523 411 0.090
regulation of protein kinase activity GO:0045859 289 0.089
cell type specific apoptotic process GO:0097285 125 0.089
regulation of response to reactive oxygen species GO:1901031 12 0.089
regulation of apoptotic signaling pathway GO:2001233 175 0.088
tissue homeostasis GO:0001894 63 0.088
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.087
peptide transport GO:0015833 74 0.086
positive regulation of cytokine production GO:0001819 167 0.086
nucleocytoplasmic transport GO:0006913 176 0.085
negative regulation of transferase activity GO:0051348 124 0.085
regulation of binding GO:0051098 111 0.084
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.083
ribonucleotide catabolic process GO:0009261 405 0.083
negative regulation of protein transport GO:0051224 75 0.082
negative regulation of multicellular organismal process GO:0051241 317 0.082
ribonucleoside catabolic process GO:0042454 406 0.082
nucleoside triphosphate metabolic process GO:0009141 422 0.081
reactive oxygen species biosynthetic process GO:1903409 4 0.081
negative regulation of apoptotic signaling pathway GO:2001234 97 0.079
positive regulation of programmed cell death GO:0043068 249 0.079
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.078
peptidyl serine modification GO:0018209 106 0.078
protein localization to nucleus GO:0034504 136 0.077
negative regulation of transport GO:0051051 176 0.076
cation transport GO:0006812 331 0.076
ion transmembrane transport GO:0034220 338 0.076
cytokine production GO:0001816 247 0.076
regulation of cytoplasmic transport GO:1903649 149 0.075
nucleoside triphosphate catabolic process GO:0009143 394 0.074
cell development GO:0048468 328 0.074
regulation of hydrogen peroxide induced cell death GO:1903205 10 0.073
regulation of ligase activity GO:0051340 29 0.072
regulation of protein deubiquitination GO:0090085 4 0.072
ubiquitin dependent protein catabolic process GO:0006511 206 0.072
alpha amino acid metabolic process GO:1901605 72 0.072
regulation of atp metabolic process GO:1903578 29 0.071
positive regulation of developmental process GO:0051094 314 0.071
regulation of intracellular transport GO:0032386 195 0.070
modification dependent macromolecule catabolic process GO:0043632 212 0.069
negative regulation of cellular protein catabolic process GO:1903363 38 0.068
proteasomal protein catabolic process GO:0010498 176 0.066
establishment of protein localization to organelle GO:0072594 172 0.066
anatomical structure homeostasis GO:0060249 100 0.065
Zebrafish
negative regulation of protein binding GO:0032091 35 0.065
regulation of cellular response to stress GO:0080135 244 0.065
epithelium development GO:0060429 227 0.063
spermatid differentiation GO:0048515 4 0.062
single organism cellular localization GO:1902580 332 0.062
regulation of response to wounding GO:1903034 101 0.061
response to nitrogen compound GO:1901698 184 0.061
negative regulation of cell proliferation GO:0008285 228 0.061
spermatid development GO:0007286 4 0.060
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.060
amide transport GO:0042886 76 0.059
protein stabilization GO:0050821 64 0.059
positive regulation of dna binding GO:0043388 17 0.059
response to other organism GO:0051707 261 0.059
protein deubiquitination GO:0016579 79 0.059
regulation of protein ubiquitination GO:0031396 95 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.058
immune system development GO:0002520 195 0.057
signal transduction by phosphorylation GO:0023014 297 0.056
system process GO:0003008 349 0.056
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.055
protein catabolic process GO:0030163 325 0.055
cellular protein catabolic process GO:0044257 261 0.055
positive regulation of oxidative stress induced cell death GO:1903209 5 0.054
innate immune response GO:0045087 178 0.053
positive regulation of cell death GO:0010942 263 0.052
positive regulation of cellular response to oxidative stress GO:1900409 7 0.052
protein export from nucleus GO:0006611 29 0.052
regulation of interleukin 8 production GO:0032677 49 0.052
monocarboxylic acid biosynthetic process GO:0072330 67 0.052
regulation of inflammatory response GO:0050727 46 0.051
nucleoside catabolic process GO:0009164 408 0.051
regulation of growth GO:0040008 165 0.051
nuclear transport GO:0051169 179 0.050
organonitrogen compound biosynthetic process GO:1901566 200 0.050
response to abiotic stimulus GO:0009628 336 0.050
regulation of transferase activity GO:0051338 355 0.050
growth GO:0040007 202 0.050
multicellular organismal homeostasis GO:0048871 67 0.050
response to organonitrogen compound GO:0010243 156 0.049
negative regulation of protein phosphorylation GO:0001933 140 0.049
long term synaptic potentiation GO:0060291 1 0.049
negative regulation of cytoplasmic transport GO:1903650 46 0.048
response to hormone GO:0009725 175 0.047
glycosyl compound catabolic process GO:1901658 413 0.046
negative regulation of immune system process GO:0002683 136 0.046
neurotransmitter uptake GO:0001504 5 0.046
immune response GO:0006955 307 0.046
neuron apoptotic process GO:0051402 39 0.045
negative regulation of binding GO:0051100 57 0.045
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.045
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.044
regulation of ubiquitin protein transferase activity GO:0051438 28 0.044
regulation of androgen receptor signaling pathway GO:0060765 18 0.043
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.043
positive regulation of transport GO:0051050 336 0.043
tissue regeneration GO:0042246 3 0.043
positive regulation of apoptotic process GO:0043065 246 0.043
atp catabolic process GO:0006200 157 0.042
phospholipid metabolic process GO:0006644 99 0.042
adult locomotory behavior GO:0008344 1 0.041
posttranscriptional regulation of gene expression GO:0010608 213 0.041
aging GO:0007568 66 0.041
nervous system development GO:0007399 293 0.041
single organism reproductive process GO:0044702 98 0.041
negative regulation of intracellular protein transport GO:0090317 42 0.041
negative regulation of catabolic process GO:0009895 104 0.041
fatty acid metabolic process GO:0006631 115 0.040
regeneration GO:0031099 4 0.040
response to drug GO:0042493 81 0.040
negative regulation of intracellular transport GO:0032387 60 0.040
regulation of neuron death GO:1901214 56 0.039
positive regulation of transporter activity GO:0032411 32 0.039
response to bacterium GO:0009617 144 0.039
regulation of peptidyl serine phosphorylation GO:0033135 50 0.039
regulation of protein catabolic process GO:0042176 155 0.039
protein oligomerization GO:0051259 173 0.038
regulation of cellular protein catabolic process GO:1903362 96 0.038
intracellular receptor signaling pathway GO:0030522 104 0.038
neuron neuron synaptic transmission GO:0007270 6 0.038
response to metal ion GO:0010038 84 0.037
Zebrafish
negative regulation of developmental process GO:0051093 247 0.037
response to external biotic stimulus GO:0043207 261 0.037
regulation of protein export from nucleus GO:0046825 15 0.037
oogenesis GO:0048477 2 0.036
cellular aldehyde metabolic process GO:0006081 20 0.036
positive regulation of transcription regulatory region dna binding GO:2000679 8 0.036
negative regulation of response to reactive oxygen species GO:1901032 10 0.036
neurological system process GO:0050877 163 0.035
synaptic transmission GO:0007268 61 0.035
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.035
catecholamine biosynthetic process GO:0042423 4 0.035
retina homeostasis GO:0001895 42 0.035
purine nucleoside catabolic process GO:0006152 398 0.035
hydrogen transport GO:0006818 23 0.034
protein targeting GO:0006605 187 0.034
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.034
immune effector process GO:0002252 159 0.034
peptidyl serine phosphorylation GO:0018105 101 0.034
negative regulation of protein kinase activity GO:0006469 98 0.033
protein homooligomerization GO:0051260 100 0.033
neuron death GO:0070997 65 0.031
multicellular organismal response to stress GO:0033555 1 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.030
cation transmembrane transport GO:0098655 238 0.029
natural killer cell mediated immunity GO:0002228 23 0.029
negative regulation of intracellular signal transduction GO:1902532 183 0.028
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.028
regulation of oxidoreductase activity GO:0051341 43 0.028
negative regulation of ubiquitin protein transferase activity GO:0051444 8 0.028
negative regulation of neuron death GO:1901215 32 0.027
dopamine uptake involved in synaptic transmission GO:0051583 4 0.027
inorganic cation transmembrane transport GO:0098662 194 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.027
dna repair GO:0006281 198 0.026
response to temperature stimulus GO:0009266 22 0.026
dopamine transport GO:0015872 5 0.026
response to toxic substance GO:0009636 37 0.026
bleb assembly GO:0032060 6 0.026
cellular protein complex assembly GO:0043623 188 0.025
glial cell migration GO:0008347 4 0.025
regulation of superoxide metabolic process GO:0090322 6 0.025
fear response GO:0042596 0 0.025
interleukin 8 production GO:0032637 51 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.025
negative regulation of cell differentiation GO:0045596 171 0.024
organelle fission GO:0048285 149 0.024
skin development GO:0043588 76 0.024
catecholamine uptake GO:0090493 4 0.024
positive regulation of lyase activity GO:0051349 16 0.024
positive regulation of apoptotic signaling pathway GO:2001235 70 0.023
nuclear export GO:0051168 69 0.023
multi organism cellular process GO:0044764 156 0.023
generation of precursor metabolites and energy GO:0006091 68 0.023
regulation of oxidative stress induced neuron death GO:1903203 9 0.023
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.023
positive regulation of oxidoreductase activity GO:0051353 26 0.023
regulation of protein targeting GO:1903533 91 0.022
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.022
regulation of peptide transport GO:0090087 62 0.022
positive regulation of interleukin 8 production GO:0032757 36 0.022
wound healing GO:0042060 115 0.021
brain development GO:0007420 97 0.021
reproduction GO:0000003 63 0.021
regulation of secretion GO:0051046 194 0.021
negative regulation of protein catabolic process GO:0042177 59 0.021
i kappab kinase nf kappab signaling GO:0007249 166 0.021
inorganic ion transmembrane transport GO:0098660 231 0.021
organic hydroxy compound transport GO:0015850 63 0.021
regulation of neuron apoptotic process GO:0043523 35 0.021
positive regulation of protein binding GO:0032092 24 0.021
response to lipid GO:0033993 206 0.020
behavior GO:0007610 112 0.020
synaptic transmission dopaminergic GO:0001963 5 0.020
behavioral defense response GO:0002209 0 0.020
myeloid cell differentiation GO:0030099 117 0.020
signal transduction by p53 class mediator GO:0072331 72 0.020
negative regulation of cellular catabolic process GO:0031330 83 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of oxidative stress induced cell death GO:1903201 24 0.020
cellular response to dna damage stimulus GO:0006974 379 0.019
epithelial cell proliferation GO:0050673 128 0.019
regulation of mapk cascade GO:0043408 262 0.019
chaperone mediated protein folding GO:0061077 13 0.019
removal of superoxide radicals GO:0019430 6 0.019
proton transport GO:0015992 22 0.019
reproductive process GO:0022414 106 0.019
regulation of lyase activity GO:0051339 23 0.018
protein targeting to nucleus GO:0044744 104 0.018
regulation of oxidative phosphorylation GO:0002082 3 0.018
regulation of protein import into nucleus GO:0042306 78 0.018
cellular response to endogenous stimulus GO:0071495 336 0.018
cyclic nucleotide metabolic process GO:0009187 82 0.018
regulation of intracellular protein transport GO:0033157 123 0.017
central nervous system development GO:0007417 123 0.017
neural nucleus development GO:0048857 47 0.017
regulation of transcription factor import into nucleus GO:0042990 39 0.017
mitochondrial transport GO:0006839 60 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
regulation of immune response GO:0050776 201 0.017
regulation of catecholamine metabolic process GO:0042069 2 0.017
cell aging GO:0007569 52 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.017
regulation of secretion by cell GO:1903530 177 0.017
negative regulation of multi organism process GO:0043901 92 0.017
regulation of protein transport GO:0051223 213 0.017
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.017
leukocyte mediated cytotoxicity GO:0001909 27 0.016
gtp metabolic process GO:0046039 239 0.016
response to peptide GO:1901652 65 0.016
cellular homeostasis GO:0019725 196 0.016
Zebrafish
maintenance of location GO:0051235 112 0.016
response to acid chemical GO:0001101 66 0.016
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.016
catechol containing compound biosynthetic process GO:0009713 4 0.016
negative regulation of oxidative stress induced neuron death GO:1903204 7 0.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.015
cellular chemical homeostasis GO:0055082 180 0.015
regulation of neurotransmitter levels GO:0001505 15 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.015
interspecies interaction between organisms GO:0044419 156 0.015
neuron death in response to oxidative stress GO:0036475 9 0.015
transcription factor import into nucleus GO:0042991 40 0.015
regulation of viral process GO:0050792 103 0.015
hemopoiesis GO:0030097 180 0.015
positive regulation of hydrolase activity GO:0051345 331 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
nuclear import GO:0051170 106 0.015
positive regulation of protein ubiquitination GO:0031398 53 0.015
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.015
erythrocyte homeostasis GO:0034101 31 0.015
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.014
regulation of transcription regulatory region dna binding GO:2000677 15 0.014
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.014
positive regulation of monooxygenase activity GO:0032770 14 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
protein k48 linked deubiquitination GO:0071108 19 0.014
dephosphorylation GO:0016311 209 0.014
unsaturated fatty acid metabolic process GO:0033559 37 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.014
regulation of protein homodimerization activity GO:0043496 9 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
post embryonic development GO:0009791 2 0.014
developmental growth GO:0048589 48 0.013
lymphocyte proliferation GO:0046651 70 0.013
rna interference GO:0016246 4 0.013
regulation of innate immune response GO:0045088 97 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
positive regulation of cellular component organization GO:0051130 376 0.013
negative regulation of leukocyte differentiation GO:1902106 24 0.013
chemical homeostasis GO:0048878 306 0.013
negative regulation of response to external stimulus GO:0032102 83 0.013
vesicle mediated transport GO:0016192 371 0.013
protein import into nucleus GO:0006606 104 0.013
negative regulation of protein ubiquitination GO:0031397 35 0.013
regulation of cellular component movement GO:0051270 334 0.013
negative regulation of protein sumoylation GO:0033234 5 0.013
membrane depolarization GO:0051899 26 0.013
head development GO:0060322 108 0.012
regulation of generation of precursor metabolites and energy GO:0043467 27 0.012
lactate metabolic process GO:0006089 1 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
response to activity GO:0014823 0 0.012
calcium ion transport GO:0006816 147 0.012
neurotransmitter transport GO:0006836 10 0.012
regulation of cell differentiation GO:0045595 393 0.012
oocyte differentiation GO:0009994 2 0.012
regulation of hormone levels GO:0010817 125 0.012
negative regulation of neuron apoptotic process GO:0043524 23 0.012
positive regulation of growth GO:0045927 58 0.012
spinal cord development GO:0021510 4 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
regulation of receptor activity GO:0010469 47 0.012
monoamine transport GO:0015844 10 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.011
defense response to other organism GO:0098542 129 0.011
positive regulation of proteolysis GO:0045862 142 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
receptor mediated endocytosis GO:0006898 84 0.011
toxin transport GO:1901998 4 0.011
reproductive system development GO:0061458 56 0.011
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.011
blastoderm segmentation GO:0007350 2 0.011
blastocyst development GO:0001824 3 0.011
oxidative phosphorylation GO:0006119 10 0.011
response to ketone GO:1901654 19 0.011
detection of stimulus GO:0051606 85 0.011
positive regulation of secretion GO:0051047 116 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
positive regulation of developmental growth GO:0048639 16 0.011
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903377 5 0.010
cellular response to oxygen levels GO:0071453 55 0.010
regulation of protein serine threonine kinase activity GO:0071900 179 0.010
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.010
protein acetylation GO:0006473 116 0.010
negative regulation of cell development GO:0010721 48 0.010

SOD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.710
nervous system disease DOID:863 431 0.710
synucleinopathy DOID:0050890 22 0.326
neurodegenerative disease DOID:1289 102 0.326
parkinson s disease DOID:14330 18 0.083
cancer DOID:162 167 0.025
disease of cellular proliferation DOID:14566 174 0.025
organ system cancer DOID:0050686 164 0.025
musculoskeletal system disease DOID:17 223 0.018