Homo sapiens

47 known processes

RANGAP1

Ran GTPase activating protein 1

(Aliases: KIAA1835,Fug1,SD,MGC20266)

RANGAP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein sumoylation GO:0016925 25 0.839
post embryonic development GO:0009791 2 0.688
protein modification by small protein conjugation GO:0032446 342 0.479
intracellular protein transport GO:0006886 270 0.384
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.320
mitotic cell cycle GO:0000278 326 0.304
Worm
determination of adult lifespan GO:0008340 2 0.269
nuclear transport GO:0051169 179 0.252
toll signaling pathway GO:0008063 2 0.228
hematopoietic or lymphoid organ development GO:0048534 186 0.224
ubiquitin dependent protein catabolic process GO:0006511 206 0.215
pharynx development GO:0060465 1 0.208
single organism membrane organization GO:0044802 268 0.204
ion transmembrane transport GO:0034220 338 0.203
response to abiotic stimulus GO:0009628 336 0.197
mitotic cell cycle process GO:1903047 286 0.192
Worm
single organism cellular localization GO:1902580 332 0.186
positive regulation of developmental process GO:0051094 314 0.180
purine ribonucleoside metabolic process GO:0046128 437 0.171
Fly
positive regulation of apoptotic process GO:0043065 246 0.162
response to hypoxia GO:0001666 96 0.162
apoptotic signaling pathway GO:0097190 268 0.158
proteasomal protein catabolic process GO:0010498 176 0.157
cellular amino acid metabolic process GO:0006520 116 0.157
transmembrane transport GO:0055085 399 0.148
locomotory behavior GO:0007626 1 0.139
regulation of protein localization GO:0032880 296 0.137
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.132
regulation of mapk cascade GO:0043408 262 0.131
positive regulation of transferase activity GO:0051347 227 0.124
membrane organization GO:0061024 292 0.121
nuclear division GO:0000280 128 0.119
cation transport GO:0006812 331 0.118
multicellular organismal aging GO:0010259 3 0.118
organophosphate catabolic process GO:0046434 430 0.117
Fly
protein modification by small protein removal GO:0070646 92 0.117
modification dependent protein catabolic process GO:0019941 209 0.116
response to oxygen levels GO:0070482 100 0.114
modification dependent macromolecule catabolic process GO:0043632 212 0.113
protein ubiquitination GO:0016567 314 0.113
positive regulation of cell death GO:0010942 263 0.111
nucleoside catabolic process GO:0009164 408 0.107
Fly
protein localization to nucleus GO:0034504 136 0.105
cell development GO:0048468 328 0.102
positive regulation of apoptotic signaling pathway GO:2001235 70 0.101
regulation of transferase activity GO:0051338 355 0.096
regulation of homeostatic process GO:0032844 121 0.095
positive regulation of programmed cell death GO:0043068 249 0.093
negative regulation of toll signaling pathway GO:0045751 1 0.093
cellular protein complex assembly GO:0043623 188 0.091
regulation of protein ubiquitination GO:0031396 95 0.091
single organism nuclear import GO:1902593 104 0.090
central nervous system projection neuron axonogenesis GO:0021952 3 0.087
negative regulation of response to external stimulus GO:0032102 83 0.086
positive regulation of organelle organization GO:0010638 195 0.084
nitrogen compound transport GO:0071705 191 0.083
positive regulation of phosphorylation GO:0042327 394 0.083
multi organism cellular process GO:0044764 156 0.082
nucleus organization GO:0006997 28 0.082
cytoplasmic transport GO:0016482 379 0.081
protein import GO:0017038 130 0.078
extrinsic apoptotic signaling pathway GO:0097191 119 0.078
oocyte differentiation GO:0009994 2 0.077
protein targeting GO:0006605 187 0.076
central nervous system neuron axonogenesis GO:0021955 3 0.072
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.071
Fly
response to oxygen containing compound GO:1901700 369 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.070
protein localization to organelle GO:0033365 280 0.068
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.068
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.067
purine nucleoside triphosphate catabolic process GO:0009146 392 0.065
Fly
endomembrane system organization GO:0010256 196 0.065
regulation of proteolysis GO:0030162 293 0.062
protein targeting to nucleus GO:0044744 104 0.061
nucleocytoplasmic transport GO:0006913 176 0.060
purine nucleoside monophosphate catabolic process GO:0009128 158 0.060
embryo development GO:0009790 123 0.060
Worm
atp metabolic process GO:0046034 176 0.059
ribonucleoside catabolic process GO:0042454 406 0.059
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.058
Fly
purine nucleoside catabolic process GO:0006152 398 0.058
Fly
regulation of ion transmembrane transport GO:0034765 132 0.058
protein k63 linked ubiquitination GO:0070534 31 0.057
definitive hemopoiesis GO:0060216 2 0.054
protein import into nucleus GO:0006606 104 0.054
regulation of toll signaling pathway GO:0008592 1 0.054
regulation of dna binding GO:0051101 37 0.053
regulation of protein maturation GO:1903317 150 0.053
regulation of purine nucleotide catabolic process GO:0033121 205 0.050
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.050
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.049
nucleoside triphosphate metabolic process GO:0009141 422 0.049
Fly
establishment of protein localization to organelle GO:0072594 172 0.047
regulation of ion transport GO:0043269 189 0.047
cellular protein catabolic process GO:0044257 261 0.045
ribonucleotide catabolic process GO:0009261 405 0.045
Fly
long chain fatty acid metabolic process GO:0001676 30 0.045
cellular homeostasis GO:0019725 196 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.044
Fly
regulation of map kinase activity GO:0043405 108 0.044
oocyte development GO:0048599 1 0.043
regulation of mitochondrion organization GO:0010821 54 0.043
free ubiquitin chain polymerization GO:0010994 2 0.042
cellular response to oxygen containing compound GO:1901701 276 0.042
ribonucleoside monophosphate catabolic process GO:0009158 158 0.041
negative regulation of proteolysis GO:0045861 132 0.041
neural crest cell development GO:0014032 3 0.040
regulation of peptidase activity GO:0052547 180 0.040
actin filament based process GO:0030029 224 0.040
mitotic nuclear division GO:0007067 119 0.040
immune response GO:0006955 307 0.040
regulation of mitochondrial membrane permeability GO:0046902 25 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
Fly
regulation of atpase activity GO:0043462 25 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.038
regulation of protein stability GO:0031647 87 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
positive regulation of protein ubiquitination GO:0031398 53 0.038
mapk cascade GO:0000165 288 0.037
oogenesis GO:0048477 2 0.036
developmental process involved in reproduction GO:0003006 66 0.036
regulation of secretion by cell GO:1903530 177 0.035
regulation of atp catabolic process GO:1903289 25 0.035
cell cell signaling GO:0007267 155 0.035
regulation of binding GO:0051098 111 0.035
protein maturation GO:0051604 233 0.034
meiotic chromosome segregation GO:0045132 4 0.034
regulation of cytoskeleton organization GO:0051493 177 0.034
protein processing GO:0016485 226 0.034
microtubule cytoskeleton organization GO:0000226 176 0.034
Worm
long chain fatty acid biosynthetic process GO:0042759 4 0.034
positive regulation of hydrolase activity GO:0051345 331 0.033
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.033
Fly
protein polymerization GO:0051258 71 0.033
ribonucleoside monophosphate metabolic process GO:0009161 187 0.033
coenzyme a metabolic process GO:0015936 6 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
Fly
protein catabolic process GO:0030163 325 0.032
maintenance of location GO:0051235 112 0.032
cation transmembrane transport GO:0098655 238 0.032
vesicle mediated transport GO:0016192 371 0.031
nervous system development GO:0007399 293 0.031
Fly
generation of neurons GO:0048699 152 0.031
protein k11 linked ubiquitination GO:0070979 24 0.031
positive regulation of proteolysis GO:0045862 142 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
hemopoiesis GO:0030097 180 0.030
cellular macromolecule catabolic process GO:0044265 380 0.029
protein localization to membrane GO:0072657 160 0.029
regulation of cell cycle GO:0051726 393 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
Fly
protein desumoylation GO:0016926 4 0.028
nucleus localization GO:0051647 1 0.028
regulation of transporter activity GO:0032409 82 0.028
organelle localization GO:0051640 84 0.028
tripartite regional subdivision GO:0007351 2 0.028
positive regulation of catabolic process GO:0009896 310 0.028
Fly
chromatin organization GO:0006325 351 0.028
cellular response to hypoxia GO:0071456 51 0.027
regulation of protein processing GO:0070613 150 0.027
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.027
cellular response to endogenous stimulus GO:0071495 336 0.027
metal ion transport GO:0030001 272 0.027
regulation of protein kinase activity GO:0045859 289 0.026
rna catabolic process GO:0006401 71 0.025
amine metabolic process GO:0009308 44 0.025
regulation of response to external stimulus GO:0032101 222 0.025
regulation of kinase activity GO:0043549 314 0.025
ncrna metabolic process GO:0034660 108 0.024
mitochondrial transport GO:0006839 60 0.024
regulation of cellular component biogenesis GO:0044087 281 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
negative regulation of phosphorylation GO:0042326 174 0.024
cell type specific apoptotic process GO:0097285 125 0.024
cellular amine metabolic process GO:0044106 41 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
Fly
negative regulation of protein processing GO:0010955 142 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
dendritic spine morphogenesis GO:0060997 3 0.023
actin cytoskeleton organization GO:0030036 207 0.023
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
neuron projection development GO:0031175 106 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
cell cycle checkpoint GO:0000075 117 0.022
ribose phosphate biosynthetic process GO:0046390 82 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
defense response GO:0006952 315 0.022
adult locomotory behavior GO:0008344 1 0.022
single organism reproductive process GO:0044702 98 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
Fly
negative regulation of cell death GO:0060548 345 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
Fly
cellular response to oxygen levels GO:0071453 55 0.021
positive regulation of protein kinase activity GO:0045860 190 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
Fly
regulation of intracellular transport GO:0032386 195 0.021
regulation of cellular response to stress GO:0080135 244 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
negative regulation of protein maturation GO:1903318 142 0.020
response to virus GO:0009615 126 0.020
gene silencing GO:0016458 49 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
Fly
double strand break repair GO:0006302 101 0.020
female gamete generation GO:0007292 2 0.020
atp catabolic process GO:0006200 157 0.020
endocytosis GO:0006897 159 0.019
mitotic cell cycle checkpoint GO:0007093 68 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
negative regulation of organelle organization GO:0010639 126 0.019
lipid homeostasis GO:0055088 39 0.019
trna metabolic process GO:0006399 35 0.019
detection of stimulus GO:0051606 85 0.019
sex differentiation GO:0007548 45 0.019
dendritic spine organization GO:0097061 4 0.019
response to external biotic stimulus GO:0043207 261 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.018
retina layer formation GO:0010842 3 0.018
anterior posterior axis specification GO:0009948 2 0.018
cell projection organization GO:0030030 252 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
spindle organization GO:0007051 53 0.018
Worm
response to calcium ion GO:0051592 46 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
rna interference GO:0016246 4 0.018
generation of precursor metabolites and energy GO:0006091 68 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
response to organic cyclic compound GO:0014070 204 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
response to transforming growth factor beta GO:0071559 94 0.017
nuclear migration GO:0007097 1 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
apoptotic mitochondrial changes GO:0008637 57 0.017
nuclear envelope reassembly GO:0031468 3 0.017
regulation of transmembrane transporter activity GO:0022898 74 0.017
cofactor catabolic process GO:0051187 7 0.017
protein polyubiquitination GO:0000209 110 0.017
nuclear import GO:0051170 106 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.016
cell projection morphogenesis GO:0048858 129 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
calcium ion transport GO:0006816 147 0.016
purine ribonucleotide biosynthetic process GO:0009152 79 0.016
cell activation GO:0001775 213 0.016
dephosphorylation GO:0016311 209 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.016
regulation of growth GO:0040008 165 0.016
reproductive process GO:0022414 106 0.016
bmp signaling pathway GO:0030509 49 0.016
response to oxidative stress GO:0006979 121 0.015
ribonucleoprotein complex biogenesis GO:0022613 116 0.015
regulation of cellular ketone metabolic process GO:0010565 50 0.015
chromosome segregation GO:0007059 114 0.015
regulation of neuron death GO:1901214 56 0.015
cellular response to oxidative stress GO:0034599 85 0.015
neuron death GO:0070997 65 0.015
sulfur compound metabolic process GO:0006790 101 0.015
secretion GO:0046903 254 0.015
coenzyme catabolic process GO:0009109 5 0.015
establishment of nucleus localization GO:0040023 1 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
reproduction GO:0000003 63 0.015
Worm
regulation of metal ion transport GO:0010959 120 0.015
mitochondrion organization GO:0007005 156 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
negative regulation of atpase activity GO:0032780 5 0.015
nucleoside bisphosphate metabolic process GO:0033865 7 0.014
response to nitrogen compound GO:1901698 184 0.014
positive regulation of ligase activity GO:0051351 19 0.014
negative regulation of catabolic process GO:0009895 104 0.014
cellular ketone metabolic process GO:0042180 80 0.014
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
Fly
monovalent inorganic cation transport GO:0015672 128 0.014
response to radiation GO:0009314 151 0.014
ribonucleoside bisphosphate metabolic process GO:0033875 7 0.014
protein oligomerization GO:0051259 173 0.013
molting cycle GO:0042303 28 0.013
negative regulation of protein ubiquitination GO:0031397 35 0.013
leukocyte activation GO:0045321 164 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
response to fungus GO:0009620 4 0.013
secretion by cell GO:0032940 226 0.013
nucleotide catabolic process GO:0009166 408 0.013
Fly
regulation of actin filament based process GO:0032970 141 0.013
positive regulation of mitochondrion organization GO:0010822 30 0.013
coenzyme metabolic process GO:0006732 65 0.013
regulation of angiogenesis GO:0045765 92 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
ribonucleotide biosynthetic process GO:0009260 81 0.013
central nervous system development GO:0007417 123 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
response to biotic stimulus GO:0009607 276 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
nucleotide biosynthetic process GO:0009165 109 0.012
regulation of immune effector process GO:0002697 91 0.012
neuron differentiation GO:0030182 138 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
anion transport GO:0006820 161 0.012
negative regulation of binding GO:0051100 57 0.012
regulation of response to cytokine stimulus GO:0060759 46 0.012
divalent metal ion transport GO:0070838 152 0.012
response to other organism GO:0051707 261 0.012
ras protein signal transduction GO:0007265 73 0.012
response to cytokine GO:0034097 232 0.012
blastoderm segmentation GO:0007350 2 0.012
segmentation GO:0035282 4 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
regulation of protein binding GO:0043393 66 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
cellular component morphogenesis GO:0032989 314 0.012
multi organism reproductive process GO:0044703 54 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
Fly
response to purine containing compound GO:0014074 40 0.012
microtubule based process GO:0007017 210 0.012
Worm
negative regulation of ion transport GO:0043271 39 0.012
chromatin modification GO:0016568 298 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
establishment of organelle localization GO:0051656 59 0.012
regulation of cell differentiation GO:0045595 393 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.011
Fly
neurogenesis GO:0022008 169 0.011
Fly
neuron development GO:0048666 113 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
establishment of ribosome localization GO:0033753 4 0.011
lipid storage GO:0019915 28 0.011
cell morphogenesis GO:0000902 296 0.011
cell cycle phase transition GO:0044770 173 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
negative regulation of defense response GO:0031348 47 0.011
innate immune response GO:0045087 178 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
regulation of system process GO:0044057 101 0.011
regulation of transmembrane transport GO:0034762 139 0.011
ribonucleoside biosynthetic process GO:0042455 25 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
Fly
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
lymphocyte differentiation GO:0030098 35 0.011
immune effector process GO:0002252 159 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of membrane permeability GO:0090559 25 0.011
actin filament organization GO:0007015 128 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
positive regulation of map kinase activity GO:0043406 80 0.011
positive regulation of chromatin modification GO:1903310 30 0.010
mrna processing GO:0006397 133 0.010
protein stabilization GO:0050821 64 0.010
intracellular receptor signaling pathway GO:0030522 104 0.010
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.010
plasma membrane organization GO:0007009 115 0.010
rna localization GO:0006403 41 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
viral life cycle GO:0019058 132 0.010
cellular chemical homeostasis GO:0055082 180 0.010
regulation of leukocyte differentiation GO:1902105 61 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
spermatid differentiation GO:0048515 4 0.010
organic acid biosynthetic process GO:0016053 97 0.010
mitochondrial membrane organization GO:0007006 40 0.010
regulation of establishment of protein localization GO:0070201 242 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.010
regulation of histone modification GO:0031056 47 0.010

RANGAP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010