Homo sapiens

25 known processes

NIT2

nitrilase family, member 2

(Aliases: MGC111199)

NIT2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.237
organophosphate catabolic process GO:0046434 430 0.147
purine nucleoside triphosphate metabolic process GO:0009144 412 0.122
purine containing compound catabolic process GO:0072523 411 0.122
nucleoside monophosphate metabolic process GO:0009123 191 0.112
lipid metabolic process GO:0006629 381 0.111
nucleoside phosphate catabolic process GO:1901292 412 0.100
ribonucleotide catabolic process GO:0009261 405 0.092
purine ribonucleoside metabolic process GO:0046128 437 0.087
positive regulation of apoptotic process GO:0043065 246 0.087
purine nucleotide catabolic process GO:0006195 405 0.085
purine nucleoside catabolic process GO:0006152 398 0.081
nucleoside triphosphate metabolic process GO:0009141 422 0.078
purine ribonucleotide catabolic process GO:0009154 404 0.074
ribonucleoside triphosphate catabolic process GO:0009203 391 0.070
ribonucleoside catabolic process GO:0042454 406 0.070
mitochondrial transport GO:0006839 60 0.070
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.066
nucleotide catabolic process GO:0009166 408 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.060
nucleoside catabolic process GO:0009164 408 0.057
oogenesis GO:0048477 2 0.056
ribonucleoside triphosphate metabolic process GO:0009199 412 0.050
glycosyl compound catabolic process GO:1901658 413 0.049
cellular lipid metabolic process GO:0044255 303 0.049
purine ribonucleoside catabolic process GO:0046130 398 0.047
protein catabolic process GO:0030163 325 0.045
cellular ketone metabolic process GO:0042180 80 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
response to oxidative stress GO:0006979 121 0.042
cellular protein catabolic process GO:0044257 261 0.040
cellular macromolecule catabolic process GO:0044265 380 0.038
gtp metabolic process GO:0046039 239 0.038
multicellular organismal aging GO:0010259 3 0.037
protein processing GO:0016485 226 0.037
secretion GO:0046903 254 0.036
apoptotic signaling pathway GO:0097190 268 0.036
monocarboxylic acid metabolic process GO:0032787 185 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
immune response GO:0006955 307 0.034
regulation of nucleoside metabolic process GO:0009118 209 0.034
system process GO:0003008 349 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.034
cellular amine metabolic process GO:0044106 41 0.033
intrinsic apoptotic signaling pathway GO:0097193 127 0.033
protein localization to organelle GO:0033365 280 0.032
defense response GO:0006952 315 0.032
female gamete generation GO:0007292 2 0.031
negative regulation of cell death GO:0060548 345 0.031
reactive oxygen species biosynthetic process GO:1903409 4 0.031
vesicle mediated transport GO:0016192 371 0.030
atp metabolic process GO:0046034 176 0.030
endocytosis GO:0006897 159 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
carbohydrate metabolic process GO:0005975 207 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
regulation of cellular response to stress GO:0080135 244 0.029
positive regulation of programmed cell death GO:0043068 249 0.029
lipid biosynthetic process GO:0008610 177 0.029
positive regulation of catabolic process GO:0009896 310 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.027
protein maturation GO:0051604 233 0.027
embryo development GO:0009790 123 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.026
positive regulation of cell death GO:0010942 263 0.026
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
positive regulation of developmental process GO:0051094 314 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
ribonucleotide biosynthetic process GO:0009260 81 0.024
alcohol metabolic process GO:0006066 114 0.024
guanosine containing compound metabolic process GO:1901068 244 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.023
mitochondrion organization GO:0007005 156 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
regulation of cysteine type endopeptidase activity GO:2000116 127 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.023
short chain fatty acid metabolic process GO:0046459 2 0.022
membrane organization GO:0061024 292 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
regulation of proteolysis GO:0030162 293 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
regulation of gtp catabolic process GO:0033124 180 0.022
locomotory behavior GO:0007626 1 0.022
cellular chemical homeostasis GO:0055082 180 0.022
regulation of peptidase activity GO:0052547 180 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
neuromuscular junction development GO:0007528 3 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
regulation of kinase activity GO:0043549 314 0.020
secretion by cell GO:0032940 226 0.020
amine metabolic process GO:0009308 44 0.020
cellular component disassembly GO:0022411 92 0.020
sulfur compound metabolic process GO:0006790 101 0.020
chemical homeostasis GO:0048878 306 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
negative regulation of immune system process GO:0002683 136 0.019
single organism membrane organization GO:0044802 268 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
inorganic ion transmembrane transport GO:0098660 231 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
ion homeostasis GO:0050801 230 0.018
positive regulation of proteolysis GO:0045862 142 0.018
determination of adult lifespan GO:0008340 2 0.018
transmembrane transport GO:0055085 399 0.018
response to abiotic stimulus GO:0009628 336 0.017
gtp catabolic process GO:0006184 237 0.017
epithelium development GO:0060429 227 0.017
cation homeostasis GO:0055080 189 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
small molecule biosynthetic process GO:0044283 157 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.017
protein oligomerization GO:0051259 173 0.017
activation of cysteine type endopeptidase activity GO:0097202 57 0.017
cell projection organization GO:0030030 252 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
fatty acid metabolic process GO:0006631 115 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
regulation of gtpase activity GO:0043087 180 0.016
cation transport GO:0006812 331 0.016
cellular ion homeostasis GO:0006873 168 0.016
organic acid biosynthetic process GO:0016053 97 0.016
negative regulation of programmed cell death GO:0043069 321 0.015
innate immune response GO:0045087 178 0.015
cellular response to oxidative stress GO:0034599 85 0.015
apoptotic mitochondrial changes GO:0008637 57 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
response to cytokine GO:0034097 232 0.015
regulation of protein kinase activity GO:0045859 289 0.015
cytokine production GO:0001816 247 0.015
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.015
atp catabolic process GO:0006200 157 0.015
nucleoside phosphate biosynthetic process GO:1901293 109 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of cytokine production GO:0001817 232 0.015
cytoplasmic transport GO:0016482 379 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of immune response GO:0050776 201 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
negative regulation of transferase activity GO:0051348 124 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
cellular protein complex assembly GO:0043623 188 0.014
regulation of secretion by cell GO:1903530 177 0.014
regulation of secretion GO:0051046 194 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
adult locomotory behavior GO:0008344 1 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
small molecule catabolic process GO:0044282 92 0.013
ion transmembrane transport GO:0034220 338 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
calcium ion transport GO:0006816 147 0.013
response to inorganic substance GO:0010035 127 0.013
protein targeting GO:0006605 187 0.013
regulation of growth GO:0040008 165 0.013
regulation of protein localization GO:0032880 296 0.012
multi organism cellular process GO:0044764 156 0.012
thioester metabolic process GO:0035383 23 0.012
regulation of protein processing GO:0070613 150 0.012
nervous system development GO:0007399 293 0.012
cellular homeostasis GO:0019725 196 0.012
oxidation reduction process GO:0055114 396 0.012
regulation of lipid metabolic process GO:0019216 96 0.012
metal ion homeostasis GO:0055065 169 0.012
positive regulation of peptidase activity GO:0010952 88 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
peptidyl serine modification GO:0018209 106 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
protein tetramerization GO:0051262 47 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
positive regulation of cytokine production GO:0001819 167 0.011
growth GO:0040007 202 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
regulation of transferase activity GO:0051338 355 0.011
monocarboxylic acid biosynthetic process GO:0072330 67 0.011
receptor mediated endocytosis GO:0006898 84 0.011
purine ribonucleoside biosynthetic process GO:0046129 23 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
cell growth GO:0016049 160 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
negative regulation of kinase activity GO:0033673 106 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
cation transmembrane transport GO:0098655 238 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
response to reactive oxygen species GO:0000302 61 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
cellular cation homeostasis GO:0030003 163 0.011
negative regulation of protein maturation GO:1903318 142 0.010
positive regulation of immune system process GO:0002684 283 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
hindbrain development GO:0030902 3 0.010
single organism cellular localization GO:1902580 332 0.010
response to oxygen containing compound GO:1901700 369 0.010
central nervous system development GO:0007417 123 0.010

NIT2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.299
inherited metabolic disorder DOID:655 242 0.299
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
amino acid metabolic disorder DOID:9252 50 0.031
neurodegenerative disease DOID:1289 102 0.024
immune system disease DOID:2914 155 0.011