Homo sapiens

16 known processes

FAF2

Fas associated factor family member 2

(Aliases: ETEA,UBXN3B,KIAA0887,UBXD8)

FAF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 380 0.870
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.865
modification dependent macromolecule catabolic process GO:0043632 212 0.832
ubiquitin dependent protein catabolic process GO:0006511 206 0.807
modification dependent protein catabolic process GO:0019941 209 0.802
protein modification by small protein conjugation GO:0032446 342 0.791
cellular protein catabolic process GO:0044257 261 0.743
protein ubiquitination GO:0016567 314 0.422
proteasomal protein catabolic process GO:0010498 176 0.383
protein catabolic process GO:0030163 325 0.318
Human
protein polyubiquitination GO:0000209 110 0.303
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.195
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.194
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.173
post embryonic development GO:0009791 2 0.163
regulation of protein ubiquitination GO:0031396 95 0.142
intracellular protein transport GO:0006886 270 0.126
Human
cellular response to misfolded protein GO:0071218 2 0.097
single organism cellular localization GO:1902580 332 0.097
Human
protein deubiquitination GO:0016579 79 0.086
response to endoplasmic reticulum stress GO:0034976 49 0.084
regulation of proteasomal protein catabolic process GO:0061136 87 0.084
regulation of cellular ketone metabolic process GO:0010565 50 0.079
vesicle mediated transport GO:0016192 371 0.076
organelle fission GO:0048285 149 0.069
regulation of protein localization GO:0032880 296 0.067
Human
mitotic cell cycle process GO:1903047 286 0.067
regulation of proteolysis GO:0030162 293 0.065
protein localization to nucleus GO:0034504 136 0.064
Human
single organism reproductive process GO:0044702 98 0.056
single organism membrane organization GO:0044802 268 0.054
protein k48 linked ubiquitination GO:0070936 38 0.054
single organism carbohydrate metabolic process GO:0044723 193 0.054
protein glycosylation GO:0006486 62 0.052
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.052
negative regulation of protein metabolic process GO:0051248 391 0.050
cytoplasmic transport GO:0016482 379 0.050
Human
regulation of protein localization to nucleus GO:1900180 85 0.050
Human
dna repair GO:0006281 198 0.049
behavior GO:0007610 112 0.049
protein targeting GO:0006605 187 0.048
Human
mitotic cell cycle GO:0000278 326 0.047
regulation of protein catabolic process GO:0042176 155 0.046
Human
cellular amino acid metabolic process GO:0006520 116 0.046
female gamete generation GO:0007292 2 0.046
cellular response to topologically incorrect protein GO:0035967 19 0.044
positive regulation of catabolic process GO:0009896 310 0.044
positive regulation of proteolysis GO:0045862 142 0.043
response to topologically incorrect protein GO:0035966 29 0.043
protein import GO:0017038 130 0.042
Human
positive regulation of protein catabolic process GO:0045732 75 0.041
positive regulation of cellular catabolic process GO:0031331 284 0.041
double strand break repair GO:0006302 101 0.040
wnt signaling pathway GO:0016055 156 0.040
chromatin modification GO:0016568 298 0.039
organophosphate catabolic process GO:0046434 430 0.039
cellular component morphogenesis GO:0032989 314 0.038
er nucleus signaling pathway GO:0006984 23 0.038
macromolecule glycosylation GO:0043413 63 0.038
regeneration GO:0031099 4 0.037
regulation of cellular protein catabolic process GO:1903362 96 0.037
regulation of chromosome organization GO:0033044 103 0.037
protein k63 linked ubiquitination GO:0070534 31 0.036
microtubule cytoskeleton organization GO:0000226 176 0.036
covalent chromatin modification GO:0016569 254 0.036
regulation of cellular response to stress GO:0080135 244 0.035
membrane fusion GO:0061025 43 0.034
cellular response to dna damage stimulus GO:0006974 379 0.034
defense response GO:0006952 315 0.033
long term memory GO:0007616 2 0.033
chromatin organization GO:0006325 351 0.033
glycosyl compound catabolic process GO:1901658 413 0.032
amine metabolic process GO:0009308 44 0.032
memory GO:0007613 3 0.032
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
positive regulation of intracellular protein transport GO:0090316 76 0.031
glycoprotein biosynthetic process GO:0009101 91 0.031
cellular ketone metabolic process GO:0042180 80 0.031
nucleocytoplasmic transport GO:0006913 176 0.031
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.030
protein localization to organelle GO:0033365 280 0.030
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
cell development GO:0048468 328 0.030
response to abiotic stimulus GO:0009628 336 0.030
multicellular organismal aging GO:0010259 3 0.030
reproductive process GO:0022414 106 0.030
negative regulation of cell death GO:0060548 345 0.029
protein modification by small protein removal GO:0070646 92 0.029
nuclear division GO:0000280 128 0.028
spermatid development GO:0007286 4 0.028
growth GO:0040007 202 0.028
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.027
glycoprotein metabolic process GO:0009100 110 0.026
oogenesis GO:0048477 2 0.025
cellular homeostasis GO:0019725 196 0.025
single organism nuclear import GO:1902593 104 0.025
Human
membrane organization GO:0061024 292 0.025
response to oxygen levels GO:0070482 100 0.024
establishment of protein localization to organelle GO:0072594 172 0.024
Human
histone h2a ubiquitination GO:0033522 17 0.023
sister chromatid segregation GO:0000819 54 0.023
nuclear import GO:0051170 106 0.023
Human
locomotory behavior GO:0007626 1 0.023
response to inorganic substance GO:0010035 127 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
response to misfolded protein GO:0051788 5 0.023
regulation of cellular amine metabolic process GO:0033238 11 0.022
nervous system development GO:0007399 293 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
spermatid differentiation GO:0048515 4 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.022
cell projection organization GO:0030030 252 0.022
limbic system development GO:0021761 3 0.022
protein maturation GO:0051604 233 0.021
determination of adult lifespan GO:0008340 2 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
inner ear morphogenesis GO:0042472 4 0.021
positive regulation of transport GO:0051050 336 0.021
blastoderm segmentation GO:0007350 2 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
nitrogen compound transport GO:0071705 191 0.021
Human
microtubule based process GO:0007017 210 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.021
gtp metabolic process GO:0046039 239 0.020
purine containing compound catabolic process GO:0072523 411 0.020
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.020
response to decreased oxygen levels GO:0036293 96 0.020
cell growth GO:0016049 160 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
ras protein signal transduction GO:0007265 73 0.019
chemotaxis GO:0006935 157 0.019
nucleoside catabolic process GO:0009164 408 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
Human
regulation of cell development GO:0060284 161 0.019
response to unfolded protein GO:0006986 24 0.019
histone modification GO:0016570 251 0.019
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
positive regulation of protein transport GO:0051222 135 0.018
regulation of dna metabolic process GO:0051052 153 0.018
regulation of canonical wnt signaling pathway GO:0060828 88 0.018
tripartite regional subdivision GO:0007351 2 0.018
neurogenesis GO:0022008 169 0.018
golgi vesicle transport GO:0048193 80 0.018
regulation of response to dna damage stimulus GO:2001020 94 0.018
chemical homeostasis GO:0048878 306 0.018
adult locomotory behavior GO:0008344 1 0.018
protein n linked glycosylation via asparagine GO:0018279 10 0.017
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
anterior posterior axis specification embryo GO:0008595 2 0.017
negative regulation of developmental process GO:0051093 247 0.017
cellular response to radiation GO:0071478 65 0.017
cell morphogenesis GO:0000902 296 0.017
immune response GO:0006955 307 0.017
negative regulation of catalytic activity GO:0043086 335 0.017
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.016
histone ubiquitination GO:0016574 31 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
regulation of histone modification GO:0031056 47 0.016
cell projection morphogenesis GO:0048858 129 0.016
myosin filament assembly GO:0031034 2 0.016
positive regulation of meiotic cell cycle GO:0051446 2 0.016
regulation of cellular component movement GO:0051270 334 0.016
mitotic nuclear division GO:0007067 119 0.016
cation transport GO:0006812 331 0.016
negative regulation of protein modification process GO:0031400 200 0.016
hindbrain development GO:0030902 3 0.016
rho protein signal transduction GO:0007266 26 0.016
positive regulation of cellular protein catabolic process GO:1903364 37 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
response to uv GO:0009411 73 0.015
regulation of cell cycle GO:0051726 393 0.015
response to hypoxia GO:0001666 96 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
cellular component disassembly GO:0022411 92 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
response to oxidative stress GO:0006979 121 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
Human
reproductive structure development GO:0048608 55 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
Human
segmentation GO:0035282 4 0.015
myosin filament organization GO:0031033 2 0.015
striated muscle myosin thick filament assembly GO:0071688 2 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
protein processing GO:0016485 226 0.015
protein import into nucleus GO:0006606 104 0.015
Human
negative regulation of hydrolase activity GO:0051346 182 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
meiotic chromosome segregation GO:0045132 4 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
Human
ribonucleoside catabolic process GO:0042454 406 0.014
endocytosis GO:0006897 159 0.014
negative regulation of protein ubiquitination GO:0031397 35 0.014
rrna metabolic process GO:0016072 40 0.014
negative regulation of organelle organization GO:0010639 126 0.014
response to oxygen containing compound GO:1901700 369 0.014
neuromuscular junction development GO:0007528 3 0.014
anterior posterior axis specification GO:0009948 2 0.014
mitotic sister chromatid separation GO:0051306 18 0.014
mrna metabolic process GO:0016071 175 0.014
nucleotide catabolic process GO:0009166 408 0.014
response to lipid GO:0033993 206 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
negative regulation of proteolysis GO:0045861 132 0.014
blood vessel morphogenesis GO:0048514 162 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
protein n linked glycosylation GO:0006487 23 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
regulation of intracellular transport GO:0032386 195 0.014
Human
regulation of gtpase activity GO:0043087 180 0.013
regulation of transferase activity GO:0051338 355 0.013
single organism membrane fusion GO:0044801 37 0.013
neurological system process GO:0050877 163 0.013
carbohydrate metabolic process GO:0005975 207 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.013
response to external biotic stimulus GO:0043207 261 0.013
dephosphorylation GO:0016311 209 0.013
regulation of cell migration GO:0030334 289 0.013
cell cycle phase transition GO:0044770 173 0.013
stem cell division GO:0017145 2 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
sequestering of metal ion GO:0051238 24 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
regulation of homeostatic process GO:0032844 121 0.013
cation transmembrane transport GO:0098655 238 0.013
ncrna catabolic process GO:0034661 14 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
spindle organization GO:0007051 53 0.013
reproductive system development GO:0061458 56 0.013
glycosylation GO:0070085 71 0.013
regulation of cell motility GO:2000145 299 0.013
cellular response to hypoxia GO:0071456 51 0.012
negative regulation of transport GO:0051051 176 0.012
Human
cellular protein complex assembly GO:0043623 188 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
meiosis i GO:0007127 4 0.012
negative regulation of protein polyubiquitination GO:1902915 4 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
hippocampus development GO:0021766 1 0.012
developmental process involved in reproduction GO:0003006 66 0.012
regulation of chromosome segregation GO:0051983 44 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.012
cation homeostasis GO:0055080 189 0.012
lipid metabolic process GO:0006629 381 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
endosomal transport GO:0016197 129 0.012
actin filament based process GO:0030029 224 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
cell part morphogenesis GO:0032990 137 0.012
golgi organization GO:0007030 38 0.012
protein stabilization GO:0050821 64 0.012
negative regulation of camp mediated signaling GO:0043951 4 0.011
response to organic cyclic compound GO:0014070 204 0.011
immune system development GO:0002520 195 0.011
organelle membrane fusion GO:0090174 5 0.011
retrograde protein transport er to cytosol GO:0030970 5 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
nuclear transport GO:0051169 179 0.011
Human
regulation of protein processing GO:0070613 150 0.011
protein localization to membrane GO:0072657 160 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of protein stability GO:0031647 87 0.011
negative regulation of response to dna damage stimulus GO:2001021 33 0.011
negative regulation of protein k63 linked ubiquitination GO:1900045 4 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
cerebellum development GO:0021549 2 0.011
myoblast fusion GO:0007520 1 0.011
regulation of cell cycle process GO:0010564 266 0.011
regulation of locomotion GO:0040012 329 0.011
regulation of chromatin modification GO:1903308 51 0.011
protein acylation GO:0043543 138 0.011
apoptotic signaling pathway GO:0097190 268 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
regulation of immune response GO:0050776 201 0.011
regulation of cell differentiation GO:0045595 393 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010
ion homeostasis GO:0050801 230 0.010
protein k63 linked deubiquitination GO:0070536 21 0.010
regulation of protein targeting GO:1903533 91 0.010
Human
guanosine containing compound metabolic process GO:1901068 244 0.010
peripheral nervous system development GO:0007422 2 0.010
angiogenesis GO:0001525 147 0.010
regulation of angiogenesis GO:0045765 92 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
positive regulation of organelle organization GO:0010638 195 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
Human
response to axon injury GO:0048678 1 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
regulation of protein transport GO:0051223 213 0.010
Human
positive regulation of protein ubiquitination GO:0031398 53 0.010
system process GO:0003008 349 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010

FAF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.022
central nervous system disease DOID:331 186 0.014
nervous system disease DOID:863 431 0.014
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
syndrome DOID:225 17 0.012
sensory system disease DOID:0050155 203 0.012
muscular disease DOID:0080000 114 0.010
muscle tissue disease DOID:66 113 0.010