|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.498
|
Rat |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.396
|
Human Rat |
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.371
|
Rat |
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.366
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.335
|
Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.332
|
Yeast |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.295
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.292
|
Human Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.289
|
Fly |
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.247
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.241
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.225
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.220
|
Yeast |
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.218
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.214
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.213
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.209
|
Fly |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.199
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.199
|
Rat |
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.183
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.182
|
Fly |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.177
|
Rat |
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.170
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.165
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.161
|
Human |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.159
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.155
|
Fly |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.155
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.149
|
Yeast Rat Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.147
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.143
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.141
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.139
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.137
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.136
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.136
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.133
|
Rat Fly |
|
|
activation of jun kinase activity
|
GO:0007257 |
7 |
0.128
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.126
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.122
|
Fly |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.120
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.118
|
Human Rat Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.117
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.114
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.113
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.112
|
Yeast |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.109
|
Rat Worm |
|
|
rna interference
|
GO:0016246 |
4 |
0.109
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.105
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.105
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.104
|
Rat |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.103
|
Rat |
|
|
response to axon injury
|
GO:0048678 |
1 |
0.103
|
Fly |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.101
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.100
|
Rat |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.099
|
Rat |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.097
|
Mouse Rat |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.094
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.094
|
Human Yeast Rat |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.094
|
Yeast |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.093
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.093
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.089
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.088
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.088
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.088
|
Mouse Rat |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.087
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.086
|
Rat |
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.086
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.083
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.082
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.081
|
Rat Fly |
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.081
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.080
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.080
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.079
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.079
|
Rat |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.078
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.078
|
|
|
|
system process
|
GO:0003008 |
349 |
0.078
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.077
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.077
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.076
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.075
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.075
|
Worm |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.074
|
Worm |
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.073
|
Yeast Worm |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.072
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.072
|
Rat Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.072
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.072
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.071
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.070
|
Rat Fly |
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.070
|
Worm |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.070
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.069
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.068
|
Fly |
|
|
muscle system process
|
GO:0003012 |
81 |
0.068
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.068
|
Mouse Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.067
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.067
|
Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.067
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.066
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.066
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.066
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.066
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.065
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.065
|
Fly |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.065
|
Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.065
|
Human Rat Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.064
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.064
|
Fly |
|
|
organelle assembly
|
GO:0070925 |
176 |
0.064
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.063
|
Rat Fly |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.063
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.062
|
Rat |
|
|
autophagy
|
GO:0006914 |
88 |
0.062
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.061
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.061
|
Fly |
|
|
taxis
|
GO:0042330 |
157 |
0.060
|
Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.060
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.060
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.058
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.058
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.058
|
Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.057
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.057
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.057
|
Fly |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.056
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.056
|
Fly |
|
|
cardiac muscle tissue growth
|
GO:0055017 |
6 |
0.056
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.054
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.053
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.053
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.053
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.053
|
Rat Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.053
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.052
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.052
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.051
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.051
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.051
|
Yeast |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.050
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.050
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.050
|
Yeast Fly |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.049
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.049
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.048
|
Rat |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.048
|
|
|
|
regulation of nitric oxide synthase biosynthetic process
|
GO:0051769 |
6 |
0.048
|
Rat |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.047
|
Human |
|
|
heart growth
|
GO:0060419 |
6 |
0.046
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.046
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.046
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.045
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.045
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.045
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.045
|
Fly |
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.045
|
Fly |
|
|
muscle hypertrophy
|
GO:0014896 |
14 |
0.045
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.045
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.045
|
Yeast Rat Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.045
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.044
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.044
|
Rat Fly |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.043
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.043
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.043
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.043
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.042
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.042
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.041
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.041
|
|
|
|
striated muscle hypertrophy
|
GO:0014897 |
14 |
0.041
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.041
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.040
|
Human Rat Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.040
|
Fly |
|
|
innate immune response
|
GO:0045087 |
178 |
0.039
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.039
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
3 |
0.039
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.039
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.039
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.039
|
Fly |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.039
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.039
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.038
|
Human |
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.038
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.038
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.038
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.038
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.038
|
Human |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.037
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.037
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.036
|
Fly |
|
|
response to wounding
|
GO:0009611 |
168 |
0.036
|
Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.036
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.036
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.036
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.036
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.036
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.035
|
Fly |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.035
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.035
|
Rat Fly |
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.035
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.035
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.034
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.034
|
Fly |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.034
|
Fly |
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.034
|
Human Rat |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.034
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.033
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.033
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.033
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.033
|
Fly |
|
|
heart development
|
GO:0007507 |
95 |
0.033
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.033
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.033
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.032
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.032
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.032
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.032
|
Fly |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.032
|
Human Rat |
|
|
vesicle localization
|
GO:0051648 |
26 |
0.032
|
Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.032
|
Human Yeast Rat Worm Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.032
|
Human Rat |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.032
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.032
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.031
|
|
|
|
growth
|
GO:0040007 |
202 |
0.031
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.031
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.031
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.031
|
Human Rat |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.031
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.030
|
Human Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.030
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.030
|
Human Rat Fly |
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.030
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.030
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.029
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.029
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.029
|
Rat |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.029
|
Fly |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.029
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.029
|
Rat |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.029
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.028
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.028
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.028
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.027
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.027
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.027
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.027
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.027
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.026
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.026
|
Human Rat |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.026
|
Rat |
|
|
gene silencing
|
GO:0016458 |
49 |
0.026
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.026
|
|
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.026
|
Worm |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.026
|
Rat Fly |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.026
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.025
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.025
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.025
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.025
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.025
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.025
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.025
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.025
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.025
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.025
|
Fly |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.024
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.024
|
|
|
|
nitric oxide synthase biosynthetic process
|
GO:0051767 |
6 |
0.024
|
Rat |
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.024
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.024
|
|
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.024
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.024
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.024
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.024
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.024
|
|
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.023
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.023
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.023
|
Yeast Worm Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.023
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.023
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.023
|
Rat |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.023
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.023
|
Rat |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.023
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.023
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.022
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.022
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.022
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.022
|
Fly |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.022
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.022
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.022
|
Fly |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.022
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.022
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.022
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.022
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.022
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.022
|
Fly |
|
|
protein targeting
|
GO:0006605 |
187 |
0.022
|
Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.022
|
Rat Fly |
|
|
viral life cycle
|
GO:0019058 |
132 |
0.022
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.022
|
Human Rat |
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.021
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.021
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.021
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.021
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.021
|
|
|
|
sensory perception of temperature stimulus
|
GO:0050951 |
1 |
0.021
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.021
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.021
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.020
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.020
|
Human |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.020
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.020
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.020
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.020
|
Rat |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.020
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.020
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.020
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.019
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.019
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.019
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.019
|
Rat |
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.019
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.019
|
Human Rat Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.019
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.019
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.019
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.019
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.019
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.018
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.018
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.018
|
Human |
|
|
microtubule based movement
|
GO:0007018 |
32 |
0.018
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.018
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.018
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.018
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.018
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.018
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.018
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.018
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.018
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.018
|
Fly |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.018
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.018
|
Rat |
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
19 |
0.018
|
Human |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.018
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.018
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.018
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.017
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
Fly |
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.017
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.017
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.017
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.017
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.017
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.017
|
Human |
|
|
cell division
|
GO:0051301 |
168 |
0.017
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.017
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.017
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.017
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.017
|
Human |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.017
|
Rat |
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.017
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.017
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.017
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.017
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.016
|
Worm |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.016
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.016
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.016
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.016
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.016
|
Yeast Fly |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.016
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.016
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.016
|
Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.016
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.016
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.016
|
Human |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.016
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.016
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.015
|
Fly |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.015
|
Fly |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.015
|
Human Rat |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.015
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
4 |
0.015
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.015
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.015
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.015
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.015
|
|
|
|
positive regulation of deacetylase activity
|
GO:0090045 |
6 |
0.015
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.015
|
Human Rat |
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.015
|
Human Yeast Worm |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.015
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.015
|
Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.015
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.015
|
Fly |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.015
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.015
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.015
|
Rat |
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.015
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.015
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.015
|
|
|
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.015
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.015
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.015
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.014
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.014
|
Fly |
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.014
|
Human |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.014
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.014
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.014
|
Yeast Worm Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.014
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.014
|
Rat |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.014
|
Rat |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.014
|
Mouse |
|
|
centrosome separation
|
GO:0051299 |
3 |
0.014
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.014
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.014
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.014
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.014
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.014
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.014
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.014
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.014
|
|
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.013
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.013
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.013
|
Yeast |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.013
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.013
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.013
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.013
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.013
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.013
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.013
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.013
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.013
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.013
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.013
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.013
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.013
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.013
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.013
|
Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.013
|
Fly |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.013
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
5 |
0.013
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.013
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.013
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.012
|
|
|
|
bradykinin catabolic process
|
GO:0010815 |
4 |
0.012
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.012
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.012
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.012
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.012
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.012
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.012
|
Rat |
|
|
organelle fusion
|
GO:0048284 |
36 |
0.012
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.012
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.012
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.012
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.012
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.012
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.012
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.012
|
|
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.012
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.012
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.012
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.012
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.012
|
|
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.012
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.012
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.012
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.012
|
Human |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.012
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.012
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.012
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.012
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.012
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.012
|
|
