Homo sapiens

33 known processes

PACS1

phosphofurin acidic cluster sorting protein 1

(Aliases: FLJ10209,KIAA1175)

PACS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of catabolic process GO:0009896 310 0.199
small gtpase mediated signal transduction GO:0007264 78 0.146
regulation of protein catabolic process GO:0042176 155 0.143
vesicle mediated transport GO:0016192 371 0.143
Mouse
golgi vesicle transport GO:0048193 80 0.118
Mouse
ras protein signal transduction GO:0007265 73 0.107
protein catabolic process GO:0030163 325 0.106
positive regulation of protein catabolic process GO:0045732 75 0.105
ribonucleoside catabolic process GO:0042454 406 0.100
nucleoside catabolic process GO:0009164 408 0.093
purine ribonucleoside catabolic process GO:0046130 398 0.093
rab protein signal transduction GO:0032482 4 0.077
post embryonic development GO:0009791 2 0.077
cellular ketone metabolic process GO:0042180 80 0.072
purine nucleoside triphosphate metabolic process GO:0009144 412 0.072
guanosine containing compound catabolic process GO:1901069 239 0.069
ribonucleoside triphosphate metabolic process GO:0009199 412 0.069
ribonucleoside triphosphate catabolic process GO:0009203 391 0.068
organophosphate catabolic process GO:0046434 430 0.068
purine containing compound catabolic process GO:0072523 411 0.065
cellular amino acid metabolic process GO:0006520 116 0.063
purine nucleotide catabolic process GO:0006195 405 0.058
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.058
regulation of locomotion GO:0040012 329 0.058
cellular amine metabolic process GO:0044106 41 0.053
regulation of small gtpase mediated signal transduction GO:0051056 156 0.052
secretion GO:0046903 254 0.051
purine ribonucleotide catabolic process GO:0009154 404 0.051
purine nucleoside triphosphate catabolic process GO:0009146 392 0.050
female gamete generation GO:0007292 2 0.050
nucleotide catabolic process GO:0009166 408 0.048
ribonucleotide catabolic process GO:0009261 405 0.048
cell development GO:0048468 328 0.048
regulation of purine nucleotide metabolic process GO:1900542 264 0.048
positive regulation of cellular amine metabolic process GO:0033240 7 0.047
regulation of cellular amine metabolic process GO:0033238 11 0.046
cellular component morphogenesis GO:0032989 314 0.046
positive regulation of cellular catabolic process GO:0031331 284 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.046
regulation of purine nucleotide catabolic process GO:0033121 205 0.045
cellular response to growth factor stimulus GO:0071363 197 0.044
amine metabolic process GO:0009308 44 0.043
inorganic ion transmembrane transport GO:0098660 231 0.043
glycosyl compound catabolic process GO:1901658 413 0.043
locomotory behavior GO:0007626 1 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
nucleoside phosphate catabolic process GO:1901292 412 0.042
secretion by cell GO:0032940 226 0.042
regulation of nucleotide metabolic process GO:0006140 269 0.042
negative regulation of phosphorus metabolic process GO:0010563 267 0.041
negative regulation of catalytic activity GO:0043086 335 0.041
positive regulation of transport GO:0051050 336 0.040
cell morphogenesis GO:0000902 296 0.040
positive regulation of hydrolase activity GO:0051345 331 0.040
single organism cellular localization GO:1902580 332 0.039
interspecies interaction between organisms GO:0044419 156 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
regulation of cellular response to growth factor stimulus GO:0090287 76 0.037
oogenesis GO:0048477 2 0.037
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
regulation of cellular component movement GO:0051270 334 0.036
multicellular organismal aging GO:0010259 3 0.036
actin filament based process GO:0030029 224 0.035
system process GO:0003008 349 0.035
mating GO:0007618 1 0.035
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.034
negative regulation of hydrolase activity GO:0051346 182 0.034
circadian behavior GO:0048512 2 0.034
positive regulation of gtpase activity GO:0043547 166 0.034
hindbrain development GO:0030902 3 0.033
response to growth factor GO:0070848 205 0.033
determination of adult lifespan GO:0008340 2 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
neuron differentiation GO:0030182 138 0.032
negative regulation of proteolysis GO:0045861 132 0.032
multi organism cellular process GO:0044764 156 0.032
gtp metabolic process GO:0046039 239 0.032
chemical homeostasis GO:0048878 306 0.032
compound eye development GO:0048749 1 0.031
cellular macromolecule catabolic process GO:0044265 380 0.030
positive regulation of nucleotide metabolic process GO:0045981 230 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
endomembrane system organization GO:0010256 196 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
regulation of gtp catabolic process GO:0033124 180 0.030
signal transduction by phosphorylation GO:0023014 297 0.030
positive regulation of locomotion GO:0040017 186 0.030
guanosine containing compound metabolic process GO:1901068 244 0.029
positive regulation of ras gtpase activity GO:0032320 117 0.029
rho protein signal transduction GO:0007266 26 0.029
protein modification by small protein conjugation GO:0032446 342 0.029
taxis GO:0042330 157 0.028
neuromuscular junction development GO:0007528 3 0.028
nucleoside triphosphate catabolic process GO:0009143 394 0.028
ion transmembrane transport GO:0034220 338 0.028
endosomal transport GO:0016197 129 0.028
nervous system development GO:0007399 293 0.028
regulation of kinase activity GO:0043549 314 0.027
oocyte development GO:0048599 1 0.027
positive regulation of phosphorylation GO:0042327 394 0.026
viral life cycle GO:0019058 132 0.026
gtp catabolic process GO:0006184 237 0.026
organonitrogen compound biosynthetic process GO:1901566 200 0.026
anterior posterior axis specification GO:0009948 2 0.026
membrane organization GO:0061024 292 0.026
ubiquitin dependent protein catabolic process GO:0006511 206 0.026
negative regulation of programmed cell death GO:0043069 321 0.025
protein autophosphorylation GO:0046777 123 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
cell projection organization GO:0030030 252 0.025
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
ion homeostasis GO:0050801 230 0.025
chromatin modification GO:0016568 298 0.025
regulation of cell cycle GO:0051726 393 0.025
cell adhesion GO:0007155 325 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
positive regulation of nucleotide catabolic process GO:0030813 185 0.024
response to abiotic stimulus GO:0009628 336 0.024
inorganic cation transmembrane transport GO:0098662 194 0.024
positive regulation of protein kinase activity GO:0045860 190 0.024
carbohydrate derivative biosynthetic process GO:1901137 207 0.024
cation transport GO:0006812 331 0.024
vacuolar transport GO:0007034 34 0.024
protein maturation GO:0051604 233 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
biological adhesion GO:0022610 331 0.023
regulation of cell migration GO:0030334 289 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
regulation of ras gtpase activity GO:0032318 128 0.022
organ morphogenesis GO:0009887 147 0.022
metal ion transport GO:0030001 272 0.022
protein targeting GO:0006605 187 0.022
cellular protein catabolic process GO:0044257 261 0.022
regulation of cell motility GO:2000145 299 0.022
maintenance of location GO:0051235 112 0.022
dephosphorylation GO:0016311 209 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
single organism membrane organization GO:0044802 268 0.022
neurogenesis GO:0022008 169 0.022
intracellular protein transport GO:0006886 270 0.022
muscle system process GO:0003012 81 0.021
cell morphogenesis involved in differentiation GO:0000904 144 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
nucleoside triphosphate metabolic process GO:0009141 422 0.021
generation of neurons GO:0048699 152 0.021
oocyte differentiation GO:0009994 2 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
cation transmembrane transport GO:0098655 238 0.021
negative regulation of protein processing GO:0010955 142 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
positive regulation of cell motility GO:2000147 177 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
protein ubiquitination GO:0016567 314 0.020
post golgi vesicle mediated transport GO:0006892 36 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
lipid metabolic process GO:0006629 381 0.020
blastoderm segmentation GO:0007350 2 0.020
negative regulation of multicellular organismal process GO:0051241 317 0.019
cell projection morphogenesis GO:0048858 129 0.019
microtubule based process GO:0007017 210 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
cellular protein complex assembly GO:0043623 188 0.019
rhythmic behavior GO:0007622 2 0.019
transmembrane transport GO:0055085 399 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
positive regulation of protein phosphorylation GO:0001934 313 0.019
positive regulation of developmental process GO:0051094 314 0.019
receptor metabolic process GO:0043112 81 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
regulation of peptidase activity GO:0052547 180 0.018
negative regulation of catabolic process GO:0009895 104 0.018
positive regulation of kinase activity GO:0033674 204 0.018
adult locomotory behavior GO:0008344 1 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
negative regulation of cell death GO:0060548 345 0.018
organ formation GO:0048645 3 0.018
anion transport GO:0006820 161 0.017
regulation of secretion GO:0051046 194 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
cellular chemical homeostasis GO:0055082 180 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
regulation of proteolysis GO:0030162 293 0.017
negative regulation of protein modification process GO:0031400 200 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
organelle assembly GO:0070925 176 0.017
nitrogen compound transport GO:0071705 191 0.017
regulation of cellular response to stress GO:0080135 244 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
amide biosynthetic process GO:0043604 15 0.017
cell fate determination GO:0001709 3 0.017
mapk cascade GO:0000165 288 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
metencephalon development GO:0022037 2 0.017
negative regulation of endopeptidase activity GO:0010951 84 0.017
regulation of endopeptidase activity GO:0052548 170 0.016
negative regulation of cell cycle GO:0045786 193 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
divalent metal ion transport GO:0070838 152 0.016
regulation of growth GO:0040008 165 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
regulation of protein maturation GO:1903317 150 0.016
sex determination GO:0007530 3 0.016
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.016
regulation of cytokine production GO:0001817 232 0.016
memory GO:0007613 3 0.016
viral process GO:0016032 146 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
endocytosis GO:0006897 159 0.016
exocytosis GO:0006887 71 0.016
cytoplasmic transport GO:0016482 379 0.016
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.016
tripartite regional subdivision GO:0007351 2 0.016
autophagy GO:0006914 88 0.015
cellular homeostasis GO:0019725 196 0.015
muscle contraction GO:0006936 73 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
spermatid differentiation GO:0048515 4 0.015
protein localization to organelle GO:0033365 280 0.015
Mouse
regulation of secretion by cell GO:1903530 177 0.015
covalent chromatin modification GO:0016569 254 0.015
cellular lipid metabolic process GO:0044255 303 0.015
associative learning GO:0008306 1 0.015
anterior posterior axis specification embryo GO:0008595 2 0.015
rna interference GO:0016246 4 0.015
limbic system development GO:0021761 3 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
myoblast fusion GO:0007520 1 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
regulation of cell development GO:0060284 161 0.015
positive regulation of cell migration GO:0030335 172 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
protein processing GO:0016485 226 0.015
peptidyl serine phosphorylation GO:0018105 101 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
intracellular mrna localization GO:0008298 1 0.014
cell part morphogenesis GO:0032990 137 0.014
response to other organism GO:0051707 261 0.014
lung alveolus development GO:0048286 4 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
neuron projection development GO:0031175 106 0.014
positive regulation of cell death GO:0010942 263 0.014
stem cell division GO:0017145 2 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
growth GO:0040007 202 0.014
regulation of gtpase activity GO:0043087 180 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
carbohydrate metabolic process GO:0005975 207 0.014
cytokine production GO:0001816 247 0.014
regulation of transmembrane transport GO:0034762 139 0.014
defense response GO:0006952 315 0.014
meiosis i GO:0007127 4 0.014
regulation of response to external stimulus GO:0032101 222 0.014
internal peptidyl lysine acetylation GO:0018393 97 0.014
striated muscle contraction GO:0006941 52 0.014
connective tissue development GO:0061448 39 0.014
nerve development GO:0021675 4 0.014
neurotransmitter secretion GO:0007269 4 0.014
ribonucleoside monophosphate catabolic process GO:0009158 158 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
inner ear morphogenesis GO:0042472 4 0.013
neuron development GO:0048666 113 0.013
response to oxygen containing compound GO:1901700 369 0.013
response to external biotic stimulus GO:0043207 261 0.013
long term memory GO:0007616 2 0.013
regulation of protein kinase activity GO:0045859 289 0.013
chemotaxis GO:0006935 157 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
epithelium migration GO:0090132 119 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
circulatory system process GO:0003013 113 0.013
regulation of protein complex assembly GO:0043254 147 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
cardiovascular system development GO:0072358 262 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
cation homeostasis GO:0055080 189 0.013
positive regulation of transferase activity GO:0051347 227 0.013
divalent inorganic cation transport GO:0072511 158 0.013
positive regulation of organelle organization GO:0010638 195 0.013
neurological system process GO:0050877 163 0.013
vacuole organization GO:0007033 44 0.013
motor neuron axon guidance GO:0008045 2 0.013
negative regulation of transforming growth factor beta production GO:0071635 4 0.013
regulation of cell cycle process GO:0010564 266 0.013
somatic stem cell maintenance GO:0035019 4 0.012
regulation of mapk cascade GO:0043408 262 0.012
chromatin organization GO:0006325 351 0.012
actin cytoskeleton organization GO:0030036 207 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
regulation of protein transport GO:0051223 213 0.012
calcium ion transport GO:0006816 147 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
regulation of transferase activity GO:0051338 355 0.012
organic anion transport GO:0015711 103 0.012
response to radiation GO:0009314 151 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
somatic muscle development GO:0007525 1 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
neural tube formation GO:0001841 3 0.012
cerebellum development GO:0021549 2 0.012
negative regulation of axonogenesis GO:0050771 4 0.012
regulation of ion transport GO:0043269 189 0.012
phospholipid metabolic process GO:0006644 99 0.012
primary neural tube formation GO:0014020 3 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
embryo development GO:0009790 123 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
neuroblast proliferation GO:0007405 4 0.012
atp metabolic process GO:0046034 176 0.012
cell division GO:0051301 168 0.012
atp catabolic process GO:0006200 157 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
oxidation reduction process GO:0055114 396 0.012
cell growth GO:0016049 160 0.012
negative regulation of cell migration GO:0030336 102 0.011
negative regulation of cytokine production GO:0001818 82 0.011
response to cytokine GO:0034097 232 0.011
cell cell signaling GO:0007267 155 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
mitotic cell cycle process GO:1903047 286 0.011
tube closure GO:0060606 3 0.011
cardiac muscle contraction GO:0060048 34 0.011
neural tube closure GO:0001843 3 0.011
actin mediated cell contraction GO:0070252 12 0.011
peripheral nervous system development GO:0007422 2 0.011
protein acylation GO:0043543 138 0.011
single organism cell adhesion GO:0098602 179 0.011
regulation of neurotransmitter secretion GO:0046928 3 0.011
regulation of cardioblast differentiation GO:0051890 4 0.011
wnt signaling pathway GO:0016055 156 0.011
visual behavior GO:0007632 2 0.011
response to transforming growth factor beta GO:0071559 94 0.011
response to biotic stimulus GO:0009607 276 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
myosin filament assembly GO:0031034 2 0.011
multicellular organismal response to stress GO:0033555 1 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of meiosis GO:0040020 3 0.011
histone modification GO:0016570 251 0.011
metal ion homeostasis GO:0055065 169 0.011
regulation of erk1 and erk2 cascade GO:0070372 99 0.011
regulation of axon guidance GO:1902667 3 0.011
epithelial cell migration GO:0010631 119 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
immune response GO:0006955 307 0.011
nuclear transport GO:0051169 179 0.011
positive regulation of immune system process GO:0002684 283 0.011
nuclear division GO:0000280 128 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
cell substrate adhesion GO:0031589 132 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
cellular ion homeostasis GO:0006873 168 0.011
glycerolipid metabolic process GO:0046486 107 0.011
spermatid development GO:0007286 4 0.011
melanin metabolic process GO:0006582 1 0.011
peptidyl serine modification GO:0018209 106 0.010
phototransduction GO:0007602 3 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
innate immune response GO:0045087 178 0.010
response to fungus GO:0009620 4 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.010
mitotic cell cycle GO:0000278 326 0.010
sensory perception of pain GO:0019233 4 0.010
transforming growth factor beta1 production GO:0032905 3 0.010
regulation of anatomical structure size GO:0090066 101 0.010
regulation of metal ion transport GO:0010959 120 0.010
tissue regeneration GO:0042246 3 0.010
negative regulation of cell proliferation GO:0008285 228 0.010
regulation of ion transmembrane transport GO:0034765 132 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010
regulation of dna metabolic process GO:0051052 153 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
neuron projection morphogenesis GO:0048812 50 0.010
engulfment of apoptotic cell GO:0043652 2 0.010
erk1 and erk2 cascade GO:0070371 104 0.010
response to oxidative stress GO:0006979 121 0.010
peptidyl tyrosine phosphorylation GO:0018108 170 0.010
tissue migration GO:0090130 119 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
sleep GO:0030431 2 0.010
regulation of cell differentiation GO:0045595 393 0.010
lipid localization GO:0010876 106 0.010
circulatory system development GO:0072359 262 0.010
forebrain generation of neurons GO:0021872 3 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010

PACS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.035
musculoskeletal system disease DOID:17 223 0.026
disease of metabolism DOID:0014667 295 0.017
inherited metabolic disorder DOID:655 242 0.017
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
muscular disease DOID:0080000 114 0.015
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
muscle tissue disease DOID:66 113 0.014
cardiovascular system disease DOID:1287 106 0.014
organ system cancer DOID:0050686 164 0.014
brain disease DOID:936 73 0.014
myopathy DOID:423 104 0.013
connective tissue disease DOID:65 109 0.012
bone disease DOID:0080001 88 0.012
gastrointestinal system cancer DOID:3119 52 0.010