Homo sapiens

103 known processes

CTCF

CCCTC-binding factor (zinc finger protein)

CTCF biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell development GO:0048468 328 0.845
chromatin modification GO:0016568 298 0.720
Human Mouse
chromatin organization GO:0006325 351 0.580
oogenesis GO:0048477 2 0.444
mrna metabolic process GO:0016071 175 0.444
regulation of meiotic cell cycle GO:0051445 4 0.440
neuron differentiation GO:0030182 138 0.409
internal protein amino acid acetylation GO:0006475 101 0.350
Mouse
organelle fission GO:0048285 149 0.341
cardiovascular system development GO:0072358 262 0.324
regulation of cell cycle process GO:0010564 266 0.305
cell morphogenesis GO:0000902 296 0.293
circulatory system development GO:0072359 262 0.288
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.286
neurogenesis GO:0022008 169 0.278
generation of neurons GO:0048699 152 0.278
nucleoside monophosphate catabolic process GO:0009125 159 0.264
nucleoside triphosphate catabolic process GO:0009143 394 0.262
negative regulation of cell differentiation GO:0045596 171 0.243
cell morphogenesis involved in differentiation GO:0000904 144 0.231
cellular response to dna damage stimulus GO:0006974 379 0.223
rna splicing GO:0008380 131 0.221
cell projection organization GO:0030030 252 0.218
cellular amino acid metabolic process GO:0006520 116 0.217
positive regulation of developmental process GO:0051094 314 0.207
nervous system development GO:0007399 293 0.201
segmentation GO:0035282 4 0.199
Fly
nucleoside catabolic process GO:0009164 408 0.196
negative regulation of cell cycle GO:0045786 193 0.196
regulation of meiosis GO:0040020 3 0.196
hemopoiesis GO:0030097 180 0.195
determination of adult lifespan GO:0008340 2 0.183
purine nucleotide catabolic process GO:0006195 405 0.178
cellular component morphogenesis GO:0032989 314 0.174
negative regulation of cell cycle process GO:0010948 121 0.172
neuron projection development GO:0031175 106 0.170
post embryonic development GO:0009791 2 0.162
negative regulation of cell death GO:0060548 345 0.161
meiosis i GO:0007127 4 0.157
purine ribonucleoside catabolic process GO:0046130 398 0.155
meiotic chromosome segregation GO:0045132 4 0.154
chemotaxis GO:0006935 157 0.153
vesicle mediated transport GO:0016192 371 0.148
taxis GO:0042330 157 0.142
nucleotide catabolic process GO:0009166 408 0.141
memory GO:0007613 3 0.140
dna conformation change GO:0071103 113 0.137
chromosome segregation GO:0007059 114 0.136
multicellular organismal aging GO:0010259 3 0.136
histone methylation GO:0016571 60 0.128
Human Mouse
skeletal system development GO:0001501 79 0.124
nucleoside phosphate catabolic process GO:1901292 412 0.121
immune response GO:0006955 307 0.120
tube development GO:0035295 125 0.120
mitotic cell cycle GO:0000278 326 0.118
neuron development GO:0048666 113 0.113
regulation of histone h3 k27 methylation GO:0061085 4 0.113
purine nucleoside triphosphate metabolic process GO:0009144 412 0.112
rna processing GO:0006396 255 0.111
cellular ketone metabolic process GO:0042180 80 0.110
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.110
short term memory GO:0007614 1 0.106
cell projection morphogenesis GO:0048858 129 0.104
establishment of nucleus localization GO:0040023 1 0.104
purine containing compound catabolic process GO:0072523 411 0.102
glycosyl compound catabolic process GO:1901658 413 0.102
nitrogen compound transport GO:0071705 191 0.102
nuclear division GO:0000280 128 0.101
ribonucleoside triphosphate catabolic process GO:0009203 391 0.099
reproductive process GO:0022414 106 0.098
neuron remodeling GO:0016322 2 0.097
response to ionizing radiation GO:0010212 65 0.097
posttranscriptional regulation of gene expression GO:0010608 213 0.094
regulation of cellular ketone metabolic process GO:0010565 50 0.092
purine nucleoside catabolic process GO:0006152 398 0.092
regulation of dna endoreduplication GO:0032875 5 0.091
positive regulation of cellular component organization GO:0051130 376 0.090
ribonucleoside triphosphate metabolic process GO:0009199 412 0.088
covalent chromatin modification GO:0016569 254 0.087
Human Mouse
single organism reproductive process GO:0044702 98 0.086
cell part morphogenesis GO:0032990 137 0.082
nucleoside triphosphate metabolic process GO:0009141 422 0.082
atp catabolic process GO:0006200 157 0.082
female gamete generation GO:0007292 2 0.081
purine nucleoside triphosphate catabolic process GO:0009146 392 0.081
lymphocyte activation GO:0046649 133 0.080
regulation of cell differentiation GO:0045595 393 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.078
central nervous system development GO:0007417 123 0.075
histone modification GO:0016570 251 0.074
Human Mouse
response to abiotic stimulus GO:0009628 336 0.074
regulation of dna metabolic process GO:0051052 153 0.074
growth GO:0040007 202 0.073
male meiosis GO:0007140 1 0.072
response to other organism GO:0051707 261 0.070
ribonucleotide catabolic process GO:0009261 405 0.069
cell cycle phase transition GO:0044770 173 0.069
double strand break repair GO:0006302 101 0.069
head development GO:0060322 108 0.069
reproductive system development GO:0061458 56 0.067
regulation of cell cycle GO:0051726 393 0.066
sex differentiation GO:0007548 45 0.065
purine nucleoside monophosphate catabolic process GO:0009128 158 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.065
nucleobase containing compound transport GO:0015931 51 0.065
embryo development GO:0009790 123 0.064
rostrocaudal neural tube patterning GO:0021903 1 0.061
vasculature development GO:0001944 181 0.061
response to external biotic stimulus GO:0043207 261 0.060
negative regulation of apoptotic process GO:0043066 316 0.060
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.058
mrna processing GO:0006397 133 0.057
positive regulation of cellular amine metabolic process GO:0033240 7 0.057
gene silencing GO:0016458 49 0.057
protein methylation GO:0006479 74 0.055
Human Mouse
stem cell development GO:0048864 69 0.054
regulation of gene expression epigenetic GO:0040029 73 0.054
sister chromatid segregation GO:0000819 54 0.053
regulation of microtubule based process GO:0032886 74 0.053
ribonucleoside monophosphate catabolic process GO:0009158 158 0.052
stem cell differentiation GO:0048863 93 0.052
regulation of cellular component biogenesis GO:0044087 281 0.052
neural tube patterning GO:0021532 2 0.051
cell type specific apoptotic process GO:0097285 125 0.050
regulation of cell cycle g1 s phase transition GO:1902806 42 0.050
mrna splicing via spliceosome GO:0000398 89 0.049
regulation of spindle organization GO:0090224 10 0.048
neuron projection morphogenesis GO:0048812 50 0.048
negative regulation of organelle organization GO:0010639 126 0.048
g1 s transition of mitotic cell cycle GO:0000082 78 0.047
immune system development GO:0002520 195 0.047
system process GO:0003008 349 0.045
adult locomotory behavior GO:0008344 1 0.045
cell activation GO:0001775 213 0.045
heart development GO:0007507 95 0.044
cell cell signaling GO:0007267 155 0.044
negative regulation of cellular component organization GO:0051129 235 0.044
meiotic cell cycle GO:0051321 13 0.043
regulation of mrna processing GO:0050684 48 0.043
embryo development ending in birth or egg hatching GO:0009792 34 0.043
organ morphogenesis GO:0009887 147 0.043
meiotic nuclear division GO:0007126 10 0.043
response to organic cyclic compound GO:0014070 204 0.042
regulation of mitotic cell cycle phase transition GO:1901990 118 0.042
reproductive structure development GO:0048608 55 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
hematopoietic or lymphoid organ development GO:0048534 186 0.040
negative regulation of programmed cell death GO:0043069 321 0.040
histone h3 k4 methylation GO:0051568 27 0.040
Human
protein localization to organelle GO:0033365 280 0.039
regulation of chromosome segregation GO:0051983 44 0.039
regulation of growth GO:0040008 165 0.039
chromatin remodeling GO:0006338 55 0.039
atp metabolic process GO:0046034 176 0.039
purine ribonucleotide catabolic process GO:0009154 404 0.039
positive regulation of cell cycle process GO:0090068 106 0.038
regulation of mrna splicing via spliceosome GO:0048024 32 0.037
dna recombination GO:0006310 77 0.037
macromolecular complex disassembly GO:0032984 60 0.037
neurological system process GO:0050877 163 0.037
locomotory behavior GO:0007626 1 0.036
proteasomal protein catabolic process GO:0010498 176 0.036
mitotic cell cycle process GO:1903047 286 0.036
dendrite morphogenesis GO:0048813 14 0.036
dna geometric change GO:0032392 32 0.036
response to biotic stimulus GO:0009607 276 0.036
negative regulation of intracellular signal transduction GO:1902532 183 0.036
secretion by cell GO:0032940 226 0.036
ribonucleoside catabolic process GO:0042454 406 0.035
dna duplex unwinding GO:0032508 30 0.035
humoral immune response GO:0006959 49 0.035
dna replication GO:0006260 116 0.035
amine metabolic process GO:0009308 44 0.035
regulation of cell cycle phase transition GO:1901987 126 0.034
positive regulation of cell proliferation GO:0008284 301 0.034
blood vessel development GO:0001568 172 0.034
developmental process involved in reproduction GO:0003006 66 0.034
nuclear transport GO:0051169 179 0.033
carbohydrate metabolic process GO:0005975 207 0.033
spermatid differentiation GO:0048515 4 0.033
dna repair GO:0006281 198 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.032
mitotic nuclear division GO:0007067 119 0.032
protein acetylation GO:0006473 116 0.032
Mouse
response to radiation GO:0009314 151 0.032
nerve development GO:0021675 4 0.032
regulation of protein localization GO:0032880 296 0.032
single organism cellular localization GO:1902580 332 0.031
secretion GO:0046903 254 0.031
oocyte development GO:0048599 1 0.031
positive regulation of immune system process GO:0002684 283 0.030
protein localization to chromatin GO:0071168 11 0.030
behavior GO:0007610 112 0.030
blastocyst development GO:0001824 3 0.029
dendrite development GO:0016358 24 0.029
appendage development GO:0048736 23 0.028
regulation of nucleotide metabolic process GO:0006140 269 0.028
cellular response to organic cyclic compound GO:0071407 127 0.028
adult behavior GO:0030534 18 0.028
regulation of protein processing GO:0070613 150 0.027
protein localization to chromosome GO:0034502 30 0.027
cytoplasmic transport GO:0016482 379 0.027
lymphocyte differentiation GO:0030098 35 0.027
regulation of mrna metabolic process GO:1903311 53 0.027
defense response GO:0006952 315 0.027
muscle structure development GO:0061061 98 0.027
regulation of cellular response to stress GO:0080135 244 0.026
nucleus localization GO:0051647 1 0.026
rna 3 end processing GO:0031123 35 0.025
transcription from rna polymerase iii promoter GO:0006383 19 0.025
histone acetylation GO:0016573 93 0.025
Mouse
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.025
cellular response to oxidative stress GO:0034599 85 0.025
dna dependent dna replication GO:0006261 44 0.024
stem cell maintenance GO:0019827 19 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
atp dependent chromatin remodeling GO:0043044 25 0.024
cellular amine metabolic process GO:0044106 41 0.023
myeloid cell differentiation GO:0030099 117 0.023
limb development GO:0060173 23 0.023
axon guidance GO:0007411 12 0.023
regulation of nuclear division GO:0051783 65 0.022
cell division GO:0051301 168 0.022
b cell activation GO:0042113 33 0.022
regulation of secretion GO:0051046 194 0.022
epithelium development GO:0060429 227 0.022
response to oxygen containing compound GO:1901700 369 0.022
positive regulation of transport GO:0051050 336 0.022
negative regulation of cell cycle phase transition GO:1901988 89 0.022
positive regulation of histone modification GO:0031058 29 0.022
negative regulation of wnt signaling pathway GO:0030178 69 0.021
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
nucleoside monophosphate metabolic process GO:0009123 191 0.021
ribonucleoprotein complex biogenesis GO:0022613 116 0.021
response to alcohol GO:0097305 64 0.021
regulation of immune response GO:0050776 201 0.021
organelle assembly GO:0070925 176 0.021
neurotransmitter secretion GO:0007269 4 0.021
apoptotic signaling pathway GO:0097190 268 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
positive regulation of cell death GO:0010942 263 0.021
positive regulation of cellular component biogenesis GO:0044089 158 0.021
gonad development GO:0008406 34 0.020
rna interference GO:0016246 4 0.020
microtubule based process GO:0007017 210 0.020
posttranscriptional gene silencing GO:0016441 25 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
nucleosome organization GO:0034728 66 0.020
regulation of intracellular transport GO:0032386 195 0.020
response to hormone GO:0009725 175 0.019
nucleic acid transport GO:0050657 39 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
organelle localization GO:0051640 84 0.019
regulation of growth hormone secretion GO:0060123 3 0.019
dna replication independent nucleosome assembly GO:0006336 27 0.018
circulatory system process GO:0003013 113 0.018
heart morphogenesis GO:0003007 48 0.018
aging GO:0007568 66 0.018
response to oxidative stress GO:0006979 121 0.018
leukocyte activation GO:0045321 164 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
ras protein signal transduction GO:0007265 73 0.018
nuclear import GO:0051170 106 0.018
cellular macromolecular complex assembly GO:0034622 324 0.017
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.017
cytokinesis GO:0000910 96 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
cellular protein catabolic process GO:0044257 261 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
neuroblast proliferation GO:0007405 4 0.017
regulation of leukocyte activation GO:0002694 115 0.017
innate immune response GO:0045087 178 0.016
signal transduction by p53 class mediator GO:0072331 72 0.016
response to inorganic substance GO:0010035 127 0.016
regulation of histone modification GO:0031056 47 0.016
Human Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
axonogenesis GO:0007409 31 0.016
blood vessel morphogenesis GO:0048514 162 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
cellular component disassembly GO:0022411 92 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
regulation of cellular amino acid metabolic process GO:0006521 6 0.016
positive regulation of cell cycle GO:0045787 140 0.016
angiogenesis GO:0001525 147 0.016
positive regulation of leukocyte activation GO:0002696 80 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
regulation of mapk cascade GO:0043408 262 0.015
pattern specification process GO:0007389 43 0.015
Fly
positive regulation of apoptotic process GO:0043065 246 0.015
chromosome condensation GO:0030261 15 0.015
axon development GO:0061564 34 0.014
mitotic sister chromatid cohesion GO:0007064 12 0.014
positive regulation of dna metabolic process GO:0051054 73 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
embryonic morphogenesis GO:0048598 85 0.014
negative regulation of developmental process GO:0051093 247 0.014
retina development in camera type eye GO:0060041 15 0.014
intracellular mrna localization GO:0008298 1 0.014
protein alkylation GO:0008213 74 0.014
Human Mouse
response to bacterium GO:0009617 144 0.014
rna transport GO:0050658 39 0.014
reproduction GO:0000003 63 0.014
negative regulation of protein metabolic process GO:0051248 391 0.014
response to oxygen levels GO:0070482 100 0.014
posttranscriptional gene silencing by rna GO:0035194 25 0.013
sensory organ development GO:0007423 52 0.013
spindle organization GO:0007051 53 0.013
brain development GO:0007420 97 0.013
response to drug GO:0042493 81 0.013
mating GO:0007618 1 0.013
positive regulation of growth GO:0045927 58 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
protein ubiquitination GO:0016567 314 0.013
cellular protein complex assembly GO:0043623 188 0.013
regionalization GO:0003002 29 0.013
Fly
membrane organization GO:0061024 292 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
protein dephosphorylation GO:0006470 81 0.013
dna packaging GO:0006323 77 0.012
cellular response to oxygen containing compound GO:1901701 276 0.012
response to fungus GO:0009620 4 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
regulation of mrna stability GO:0043488 23 0.012
positive regulation of protein transport GO:0051222 135 0.012
dna templated transcription initiation GO:0006352 35 0.012
sister chromatid cohesion GO:0007062 24 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
regulation of protein transport GO:0051223 213 0.012
developmental maturation GO:0021700 28 0.012
mrna transport GO:0051028 30 0.012
histone exchange GO:0043486 3 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
protein localization to nucleus GO:0034504 136 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
response to nitrogen compound GO:1901698 184 0.011
cell cycle g1 s phase transition GO:0044843 80 0.011
cranial nerve development GO:0021545 4 0.011
leukocyte differentiation GO:0002521 98 0.011
regulation of microtubule cytoskeleton organization GO:0070507 61 0.011
spermatid development GO:0007286 4 0.011
protein targeting GO:0006605 187 0.011
dna modification GO:0006304 27 0.011
Mouse
regulation of secretion by cell GO:1903530 177 0.011
regulation of protein complex assembly GO:0043254 147 0.011
protein modification by small protein removal GO:0070646 92 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
patterning of blood vessels GO:0001569 2 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
positive regulation of histone methylation GO:0031062 12 0.011
ossification GO:0001503 121 0.010
cellular response to external stimulus GO:0071496 111 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
regulation of leukocyte proliferation GO:0070663 67 0.010
positive regulation of cell activation GO:0050867 81 0.010
fibroblast apoptotic process GO:0044346 8 0.010
intracellular protein transport GO:0006886 270 0.010
cell maturation GO:0048469 11 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.010
development of primary sexual characteristics GO:0045137 35 0.010
dna replication independent nucleosome organization GO:0034724 27 0.010

CTCF disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.047
central nervous system disease DOID:331 186 0.019
neurodegenerative disease DOID:1289 102 0.019
nervous system disease DOID:863 431 0.019
cognitive disorder DOID:1561 29 0.017
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013