Homo sapiens

95 known processes

BLK

B lymphoid tyrosine kinase

(Aliases: MGC10442,MODY11)

BLK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 44 0.458
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.348
enzyme linked receptor protein signaling pathway GO:0007167 303 0.332
Human
positive regulation of immune system process GO:0002684 283 0.321
positive regulation of phosphorylation GO:0042327 394 0.279
Human Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.223
leukocyte activation GO:0045321 164 0.191
Human
immune response GO:0006955 307 0.177
immune system development GO:0002520 195 0.174
Human
cellular ketone metabolic process GO:0042180 80 0.156
anatomical structure formation involved in morphogenesis GO:0048646 284 0.154
Worm Fly
activation of immune response GO:0002253 114 0.153
cellular amino acid metabolic process GO:0006520 116 0.153
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.150
negative regulation of programmed cell death GO:0043069 321 0.149
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.132
cell activation GO:0001775 213 0.127
Human
mapk cascade GO:0000165 288 0.126
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.125
positive regulation of mapk cascade GO:0043410 190 0.121
regulation of transferase activity GO:0051338 355 0.112
Human Fly
immune response regulating signaling pathway GO:0002764 97 0.109
positive regulation of cell proliferation GO:0008284 301 0.108
Human
regulation of mapk cascade GO:0043408 262 0.108
regulation of immune response GO:0050776 201 0.107
regulation of cellular amine metabolic process GO:0033238 11 0.106
negative regulation of protein metabolic process GO:0051248 391 0.104
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.102
Human
immune response activating signal transduction GO:0002757 90 0.100
cellular response to endogenous stimulus GO:0071495 336 0.100
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
positive regulation of immune response GO:0050778 159 0.096
positive regulation of cellular amine metabolic process GO:0033240 7 0.094
cellular response to cytokine stimulus GO:0071345 181 0.088
Human
regulation of locomotion GO:0040012 329 0.082
Human
g protein coupled receptor signaling pathway GO:0007186 207 0.080
negative regulation of cellular protein metabolic process GO:0032269 353 0.080
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.079
regulation of kinase activity GO:0043549 314 0.078
Human Fly
response to bacterium GO:0009617 144 0.077
female gamete generation GO:0007292 2 0.077
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.075
response to oxygen containing compound GO:1901700 369 0.074
Human
regulation of protein kinase activity GO:0045859 289 0.073
Human Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.073
vasculature development GO:0001944 181 0.071
regulation of nucleotide metabolic process GO:0006140 269 0.071
regulation of cell migration GO:0030334 289 0.069
Human
cellular response to dna damage stimulus GO:0006974 379 0.068
metal ion transport GO:0030001 272 0.067
regulation of cell cycle GO:0051726 393 0.067
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.066
negative regulation of apoptotic process GO:0043066 316 0.065
Human
signal transduction by phosphorylation GO:0023014 297 0.065
circulatory system development GO:0072359 262 0.064
peptidyl tyrosine phosphorylation GO:0018108 170 0.064
regulation of cell differentiation GO:0045595 393 0.062
Human
tissue migration GO:0090130 119 0.062
Human
purine nucleoside triphosphate catabolic process GO:0009146 392 0.062
hemopoiesis GO:0030097 180 0.061
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.059
Human
cellular amine metabolic process GO:0044106 41 0.058
response to other organism GO:0051707 261 0.058
sequestering of calcium ion GO:0051208 17 0.057
response to external biotic stimulus GO:0043207 261 0.057
regulation of apoptotic signaling pathway GO:2001233 175 0.057
Human
defense response to other organism GO:0098542 129 0.057
positive regulation of hydrolase activity GO:0051345 331 0.056
Human
nucleotide catabolic process GO:0009166 408 0.056
cation homeostasis GO:0055080 189 0.054
Human
vesicle mediated transport GO:0016192 371 0.053
Human
regulation of cell cycle process GO:0010564 266 0.053
negative regulation of homeostatic process GO:0032845 59 0.053
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.053
negative regulation of cell death GO:0060548 345 0.052
Human
divalent metal ion transport GO:0070838 152 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.051
cation transport GO:0006812 331 0.051
metal ion homeostasis GO:0055065 169 0.050
Human
regulation of cell motility GO:2000145 299 0.050
Human
defense response GO:0006952 315 0.050
Human
response to abiotic stimulus GO:0009628 336 0.050
purine nucleotide catabolic process GO:0006195 405 0.048
guanosine containing compound catabolic process GO:1901069 239 0.048
purine nucleoside triphosphate metabolic process GO:0009144 412 0.048
negative regulation of protein modification process GO:0031400 200 0.048
Human
positive regulation of map kinase activity GO:0043406 80 0.048
small gtpase mediated signal transduction GO:0007264 78 0.047
lipid metabolic process GO:0006629 381 0.047
Human
erk1 and erk2 cascade GO:0070371 104 0.046
negative regulation of cellular amine metabolic process GO:0033239 3 0.046
negative regulation of catalytic activity GO:0043086 335 0.045
Human
cytokine mediated signaling pathway GO:0019221 109 0.045
Human
response to organonitrogen compound GO:0010243 156 0.045
positive regulation of nucleotide metabolic process GO:0045981 230 0.045
motor neuron axon guidance GO:0008045 2 0.045
negative regulation of phosphorus metabolic process GO:0010563 267 0.044
Human
positive regulation of developmental process GO:0051094 314 0.044
Human
regulation of cytokine production GO:0001817 232 0.044
Human
epithelial cell migration GO:0010631 119 0.044
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.043
hindbrain development GO:0030902 3 0.043
transmembrane transport GO:0055085 399 0.043
post embryonic development GO:0009791 2 0.042
response to lipid GO:0033993 206 0.042
Human
positive regulation of locomotion GO:0040017 186 0.042
nucleoside triphosphate metabolic process GO:0009141 422 0.042
organophosphate catabolic process GO:0046434 430 0.041
regulation of protein serine threonine kinase activity GO:0071900 179 0.040
purine ribonucleoside metabolic process GO:0046128 437 0.040
guanosine containing compound metabolic process GO:1901068 244 0.040
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
lymphocyte activation GO:0046649 133 0.040
Human
purine containing compound catabolic process GO:0072523 411 0.040
activation of protein kinase activity GO:0032147 90 0.039
nervous system development GO:0007399 293 0.039
Human Fly
response to biotic stimulus GO:0009607 276 0.039
regulation of map kinase activity GO:0043405 108 0.039
cardiovascular system development GO:0072358 262 0.039
regulation of calcium ion transport into cytosol GO:0010522 33 0.038
positive regulation of cell cycle GO:0045787 140 0.038
chemical homeostasis GO:0048878 306 0.038
Human
cell development GO:0048468 328 0.038
Human Fly
regulation of transmembrane transporter activity GO:0022898 74 0.038
cytoplasmic transport GO:0016482 379 0.038
Human
mitotic cell cycle GO:0000278 326 0.038
Worm
positive regulation of nucleotide catabolic process GO:0030813 185 0.038
neurogenesis GO:0022008 169 0.038
Human Fly
positive regulation of cell cycle process GO:0090068 106 0.037
associative learning GO:0008306 1 0.037
Fly
epithelium migration GO:0090132 119 0.037
Human
glycosyl compound catabolic process GO:1901658 413 0.036
nucleoside catabolic process GO:0009164 408 0.036
cellular response to nitrogen compound GO:1901699 144 0.036
negative regulation of protein phosphorylation GO:0001933 140 0.036
Human
ribonucleotide catabolic process GO:0009261 405 0.036
oogenesis GO:0048477 2 0.036
Fly
regulation of ion transmembrane transport GO:0034765 132 0.036
calcium ion transport into cytosol GO:0060402 48 0.036
ribonucleoside catabolic process GO:0042454 406 0.035
ras protein signal transduction GO:0007265 73 0.034
regulation of neurotrophin trk receptor signaling pathway GO:0051386 2 0.034
secretion GO:0046903 254 0.034
covalent chromatin modification GO:0016569 254 0.033
actin filament based process GO:0030029 224 0.033
Human Fly
inorganic ion transmembrane transport GO:0098660 231 0.033
angiogenesis GO:0001525 147 0.033
positive regulation of store operated calcium channel activity GO:1901341 4 0.033
lymphocyte proliferation GO:0046651 70 0.033
gtp metabolic process GO:0046039 239 0.033
regulation of calcium ion transport GO:0051924 79 0.033
glial cell migration GO:0008347 4 0.032
positive regulation of catabolic process GO:0009896 310 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.031
regulation of purine nucleotide catabolic process GO:0033121 205 0.031
ameboidal type cell migration GO:0001667 135 0.031
Human
purine nucleoside catabolic process GO:0006152 398 0.031
antigen receptor mediated signaling pathway GO:0050851 38 0.031
system process GO:0003008 349 0.031
Fly
cellular response to oxygen containing compound GO:1901701 276 0.031
Human
blood vessel development GO:0001568 172 0.031
cellular lipid metabolic process GO:0044255 303 0.030
Human
mitotic cell cycle process GO:1903047 286 0.030
Worm
protein processing GO:0016485 226 0.030
Human
positive regulation of cellular component movement GO:0051272 181 0.030
chromatin modification GO:0016568 298 0.030
cellular component morphogenesis GO:0032989 314 0.030
Human Fly
cellular response to hormone stimulus GO:0032870 125 0.029
regulation of metal ion transport GO:0010959 120 0.029
positive regulation of intracellular transport GO:0032388 104 0.029
chromatin organization GO:0006325 351 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
Fly
cellular metal ion homeostasis GO:0006875 146 0.029
Human
mononuclear cell proliferation GO:0032943 71 0.029
maintenance of location GO:0051235 112 0.029
positive regulation of kinase activity GO:0033674 204 0.029
Human Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
Human
cellular response to lipid GO:0071396 127 0.028
Human
organophosphate biosynthetic process GO:0090407 163 0.028
protein acylation GO:0043543 138 0.028
melanin metabolic process GO:0006582 1 0.028
negative regulation of kinase activity GO:0033673 106 0.028
Human
calcium ion transmembrane transport GO:0070588 76 0.028
positive regulation of cell motility GO:2000147 177 0.028
regulation of leukocyte activation GO:0002694 115 0.027
Human
regulation of gtpase activity GO:0043087 180 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
regulation of ion transmembrane transporter activity GO:0032412 72 0.027
endothelial cell migration GO:0043542 86 0.027
cation transmembrane transport GO:0098655 238 0.027
lymphocyte differentiation GO:0030098 35 0.027
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.027
regulation of epithelial cell migration GO:0010632 93 0.027
Human
regulation of gtp catabolic process GO:0033124 180 0.027
innate immune response GO:0045087 178 0.026
Human
regulation of transmembrane transport GO:0034762 139 0.026
positive regulation of ion transport GO:0043270 87 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
Human
response to cytokine GO:0034097 232 0.026
Human
photoreceptor cell differentiation GO:0046530 2 0.026
regulation of ion transport GO:0043269 189 0.026
regulation of ion homeostasis GO:2000021 73 0.026
Human
memory GO:0007613 3 0.026
Fly
epithelium development GO:0060429 227 0.025
Fly
positive regulation of transferase activity GO:0051347 227 0.025
Human Fly
regulation of ras protein signal transduction GO:0046578 155 0.025
calcium ion transport GO:0006816 147 0.025
immune effector process GO:0002252 159 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
Human
regulation of angiogenesis GO:0045765 92 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.025
regulation of cell activation GO:0050865 125 0.025
Human
ion homeostasis GO:0050801 230 0.025
Human
calcium ion homeostasis GO:0055074 122 0.025
regulation of peptidase activity GO:0052547 180 0.024
Human
regulation of vasculature development GO:1901342 97 0.024
cellular divalent inorganic cation homeostasis GO:0072503 128 0.024
Human
regulation of cellular response to stress GO:0080135 244 0.024
positive regulation of cell death GO:0010942 263 0.024
Human
regulation of nucleotide catabolic process GO:0030811 205 0.024
negative regulation of transport GO:0051051 176 0.024
regulation of secretion by cell GO:1903530 177 0.024
second messenger mediated signaling GO:0019932 78 0.024
gtp catabolic process GO:0006184 237 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
Human
response to organic cyclic compound GO:0014070 204 0.024
peptidyl tyrosine modification GO:0018212 170 0.024
regulation of purine nucleotide metabolic process GO:1900542 264 0.024
neurological system process GO:0050877 163 0.023
Fly
protein maturation GO:0051604 233 0.023
Human
metencephalon development GO:0022037 2 0.023
cellular calcium ion homeostasis GO:0006874 117 0.023
cytosolic calcium ion homeostasis GO:0051480 89 0.023
regulation of cellular component movement GO:0051270 334 0.023
Human
response to nitrogen compound GO:1901698 184 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
regulation of intracellular transport GO:0032386 195 0.023
Human
leukocyte proliferation GO:0070661 74 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.023
single organism cellular localization GO:1902580 332 0.022
Worm
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
blood vessel morphogenesis GO:0048514 162 0.022
cellular homeostasis GO:0019725 196 0.022
Human
regulation of proteolysis GO:0030162 293 0.022
Human
regulation of neuron migration GO:2001222 3 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
leukocyte differentiation GO:0002521 98 0.022
Human
regulation of response to external stimulus GO:0032101 222 0.022
negative regulation of protein kinase activity GO:0006469 98 0.022
Human
neuron differentiation GO:0030182 138 0.022
Human Fly
cellular protein catabolic process GO:0044257 261 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.021
reactive nitrogen species metabolic process GO:2001057 3 0.021
inorganic cation transmembrane transport GO:0098662 194 0.021
myeloid cell differentiation GO:0030099 117 0.021
response to inorganic substance GO:0010035 127 0.021
negative regulation of cell cycle GO:0045786 193 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
catagen GO:0042637 3 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
cellular response to abiotic stimulus GO:0071214 117 0.021
b cell activation GO:0042113 33 0.021
positive regulation of cell migration GO:0030335 172 0.021
response to peptide GO:1901652 65 0.021
growth GO:0040007 202 0.021
Fly
positive regulation of cytoplasmic transport GO:1903651 82 0.021
lipid biosynthetic process GO:0008610 177 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.020
cell division GO:0051301 168 0.020
regulation of membrane potential GO:0042391 95 0.020
Human
segmentation GO:0035282 4 0.020
fear response GO:0042596 0 0.020
myoblast fusion GO:0007520 1 0.020
cannabinoid signaling pathway GO:0038171 2 0.020
cellular cation homeostasis GO:0030003 163 0.020
Human
secretion by cell GO:0032940 226 0.020
regulation of mitotic cell cycle GO:0007346 189 0.020
cellular response to organonitrogen compound GO:0071417 124 0.020
cytokine production GO:0001816 247 0.020
Human
cell projection organization GO:0030030 252 0.020
Human Fly
protein ubiquitination GO:0016567 314 0.020
phosphatidylinositol mediated signaling GO:0048015 55 0.020
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
cellular ion homeostasis GO:0006873 168 0.020
Human
b cell receptor signaling pathway GO:0050853 18 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
Human
positive regulation of transport GO:0051050 336 0.019
response to hormone GO:0009725 175 0.019
membrane organization GO:0061024 292 0.019
sequestering of metal ion GO:0051238 24 0.019
positive regulation of protein kinase activity GO:0045860 190 0.019
Fly
eye photoreceptor cell differentiation GO:0001754 2 0.019
rab protein signal transduction GO:0032482 4 0.019
response to growth factor GO:0070848 205 0.019
Human
internal peptidyl lysine acetylation GO:0018393 97 0.019
mating GO:0007618 1 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.019
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.019
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.019
positive regulation of angiogenesis GO:0045766 51 0.019
positive regulation of endothelial cell migration GO:0010595 39 0.019
determination of adult lifespan GO:0008340 2 0.019
stress activated mapk cascade GO:0051403 93 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
endocytosis GO:0006897 159 0.018
Human
regulation of cytoplasmic transport GO:1903649 149 0.018
Human
regulation of postsynaptic membrane potential GO:0060078 1 0.018
inositol lipid mediated signaling GO:0048017 55 0.018
Human
actin filament organization GO:0007015 128 0.018
Human Fly
regulation of erk1 and erk2 cascade GO:0070372 99 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
peripheral nervous system development GO:0007422 2 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.018
regulation of erbb signaling pathway GO:1901184 27 0.018
response to light stimulus GO:0009416 87 0.018
thymus development GO:0048538 3 0.018
histone modification GO:0016570 251 0.018
divalent inorganic cation transport GO:0072511 158 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
Fly
cell morphogenesis GO:0000902 296 0.017
Human Fly
regulation of transporter activity GO:0032409 82 0.017
multicellular organismal response to stress GO:0033555 1 0.017
positive regulation of cell division GO:0051781 59 0.017
chemotaxis GO:0006935 157 0.017
Fly
peptidyl threonine phosphorylation GO:0018107 41 0.017
regulation of neural precursor cell proliferation GO:2000177 4 0.017
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 11 0.017
cell part morphogenesis GO:0032990 137 0.017
Fly
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.017
protein catabolic process GO:0030163 325 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
generation of neurons GO:0048699 152 0.017
Human Fly
regulation of myeloid cell differentiation GO:0045637 81 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
erbb signaling pathway GO:0038127 44 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
Human
compound eye development GO:0048749 1 0.016
regulation of homeostatic process GO:0032844 121 0.016
Human
axon regeneration GO:0031103 1 0.016
negative regulation of reactive oxygen species biosynthetic process GO:1903427 1 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
release of sequestered calcium ion into cytosol GO:0051209 41 0.016
response to radiation GO:0009314 151 0.016
protein localization to organelle GO:0033365 280 0.016
regulation of protein maturation GO:1903317 150 0.016
Human
dephosphorylation GO:0016311 209 0.016
Human
regulation of endothelial cell migration GO:0010594 67 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
Human
male genitalia development GO:0030539 1 0.016
positive regulation of mononuclear cell proliferation GO:0032946 47 0.016
regulation of secretion GO:0051046 194 0.016
oocyte development GO:0048599 1 0.016
sphingosine 1 phosphate signaling pathway GO:0003376 1 0.016
phospholipid metabolic process GO:0006644 99 0.016
Human
cellular chemical homeostasis GO:0055082 180 0.016
Human
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.016
adult locomotory behavior GO:0008344 1 0.016
receptor internalization GO:0031623 43 0.016
positive regulation of neural precursor cell proliferation GO:2000179 2 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
organ formation GO:0048645 3 0.015
jnk cascade GO:0007254 80 0.015
muscle system process GO:0003012 81 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
response to peptide hormone GO:0043434 61 0.015
striated muscle contraction GO:0006941 52 0.015
microtubule based process GO:0007017 210 0.015
Worm
carbohydrate metabolic process GO:0005975 207 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
regulation of cell growth GO:0001558 135 0.015
ion transmembrane transport GO:0034220 338 0.015
calcium mediated signaling GO:0019722 44 0.015
protein acetylation GO:0006473 116 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
Human
regulation of jnk cascade GO:0046328 73 0.015
cell cell signaling GO:0007267 155 0.015
forebrain generation of neurons GO:0021872 3 0.015
negative regulation of proteolysis GO:0045861 132 0.015
Human
rna processing GO:0006396 255 0.015
regulation of epithelial cell proliferation GO:0050678 113 0.015
apoptotic signaling pathway GO:0097190 268 0.015
Human
rho protein signal transduction GO:0007266 26 0.015
peptidyl serine modification GO:0018209 106 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
Human
phosphatidylinositol metabolic process GO:0046488 53 0.015
Human
positive regulation of apoptotic process GO:0043065 246 0.015
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
protein autophosphorylation GO:0046777 123 0.015
Human Worm
visual behavior GO:0007632 2 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
regulation of cell division GO:0051302 116 0.015
regeneration GO:0031099 4 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
Human
blastoderm segmentation GO:0007350 2 0.015
tissue regeneration GO:0042246 3 0.014
detection of stimulus GO:0051606 85 0.014
oxidation reduction process GO:0055114 396 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
regulation of phagocytosis engulfment GO:0060099 2 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
Human
cell cycle phase transition GO:0044770 173 0.014
negative regulation of transferase activity GO:0051348 124 0.014
Human
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.014
Human
dna repair GO:0006281 198 0.014
positive regulation of leukocyte activation GO:0002696 80 0.014
Human
multicellular organismal aging GO:0010259 3 0.014
small molecule biosynthetic process GO:0044283 157 0.014
activation of mapk activity GO:0000187 45 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of cation channel activity GO:2001257 33 0.014
cell projection assembly GO:0030031 126 0.014
response to virus GO:0009615 126 0.014
peptidyl serine phosphorylation GO:0018105 101 0.014
protein localization to nucleus GO:0034504 136 0.014
i kappab kinase nf kappab signaling GO:0007249 166 0.014
positive regulation of stress activated mapk cascade GO:0032874 60 0.014
dna replication GO:0006260 116 0.014
methylation GO:0032259 106 0.014
positive regulation of jnk cascade GO:0046330 52 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
negative regulation of protein processing GO:0010955 142 0.014
Human
carbohydrate transport GO:0008643 37 0.014
neuron projection regeneration GO:0031102 1 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
Fly
macromolecule methylation GO:0043414 97 0.014
asymmetric stem cell division GO:0098722 1 0.013
regulation of vesicle mediated transport GO:0060627 130 0.013
Human
response to insulin GO:0032868 45 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
regulation of growth GO:0040008 165 0.013
Fly
regulation of reactive oxygen species metabolic process GO:2000377 41 0.013
muscle contraction GO:0006936 73 0.013
cellular response to peptide GO:1901653 59 0.013
nucleocytoplasmic transport GO:0006913 176 0.013
regulation of response to dna damage stimulus GO:2001020 94 0.013
cell projection morphogenesis GO:0048858 129 0.013
Fly
positive regulation of behavior GO:0048520 60 0.013
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
epithelial cell proliferation GO:0050673 128 0.013
purine nucleotide biosynthetic process GO:0006164 84 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
nerve development GO:0021675 4 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
peptidyl lysine modification GO:0018205 144 0.013
protein oligomerization GO:0051259 173 0.013
Human
visual learning GO:0008542 1 0.013
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.013
cellular defense response GO:0006968 2 0.013
circulatory system process GO:0003013 113 0.013
regulation of leukocyte proliferation GO:0070663 67 0.013
positive regulation of leukocyte proliferation GO:0070665 48 0.013
purine containing compound biosynthetic process GO:0072522 88 0.013
regulation of glucocorticoid secretion GO:2000849 4 0.013
sensory perception of light stimulus GO:0050953 35 0.013
receptor metabolic process GO:0043112 81 0.013
negative regulation of cell cycle process GO:0010948 121 0.012
t cell activation GO:0042110 99 0.012
Human
negative regulation of organelle organization GO:0010639 126 0.012
wnt signaling pathway GO:0016055 156 0.012
blood circulation GO:0008015 113 0.012
mitochondrion organization GO:0007005 156 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
Human
positive regulation of endothelial cell development GO:1901552 1 0.012
behavior GO:0007610 112 0.012
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
organelle fission GO:0048285 149 0.012
cerebellum development GO:0021549 2 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012

BLK disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.161
Human
primary immunodeficiency disease DOID:612 36 0.119
Human
b cell deficiency DOID:2115 17 0.119
Human
hematopoietic system disease DOID:74 100 0.091
Human
blood protein disease DOID:620 16 0.053
Human
cancer DOID:162 167 0.043
disease of cellular proliferation DOID:14566 174 0.043
organ system cancer DOID:0050686 164 0.043
agammaglobulinemia DOID:2583 16 0.036
Human
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
sensory system disease DOID:0050155 203 0.024
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.018
disease of metabolism DOID:0014667 295 0.017
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
neurodegenerative disease DOID:1289 102 0.013