Homo sapiens

48 known processes

ATXN3

ataxin 3

(Aliases: ATX3,MJD,JOS,AT3,SCA3,MJD1)

ATXN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.987
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.980
Mouse
modification dependent protein catabolic process GO:0019941 209 0.973
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.953
Mouse
protein modification by small protein conjugation GO:0032446 342 0.906
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.889
proteasomal protein catabolic process GO:0010498 176 0.837
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.746
Mouse
protein ubiquitination GO:0016567 314 0.744
protein catabolic process GO:0030163 325 0.667
Mouse
cellular protein catabolic process GO:0044257 261 0.647
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.537
protein polyubiquitination GO:0000209 110 0.516
multi organism cellular process GO:0044764 156 0.514
nucleoside phosphate catabolic process GO:1901292 412 0.512
regulation of proteasomal protein catabolic process GO:0061136 87 0.451
hemopoiesis GO:0030097 180 0.434
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.433
regulation of multi organism process GO:0043900 157 0.428
cellular macromolecule catabolic process GO:0044265 380 0.414
Mouse
regulation of proteolysis GO:0030162 293 0.414
dna repair GO:0006281 198 0.398
viral process GO:0016032 146 0.392
regulation of cellular protein catabolic process GO:1903362 96 0.368
single organism carbohydrate metabolic process GO:0044723 193 0.366
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.340
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.305
epithelial cell differentiation GO:0030855 141 0.293
organophosphate catabolic process GO:0046434 430 0.287
response to endoplasmic reticulum stress GO:0034976 49 0.280
negative regulation of protein metabolic process GO:0051248 391 0.268
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.263
response to salt stress GO:0009651 3 0.258
protein deubiquitination GO:0016579 79 0.255
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.246
segmentation GO:0035282 4 0.245
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 30 0.243
regulation of protein catabolic process GO:0042176 155 0.233
ribonucleotide catabolic process GO:0009261 405 0.232
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.231
positive regulation of cellular protein catabolic process GO:1903364 37 0.220
negative regulation of catalytic activity GO:0043086 335 0.216
purine ribonucleotide catabolic process GO:0009154 404 0.213
autophagy GO:0006914 88 0.208
response to uv GO:0009411 73 0.202
histone modification GO:0016570 251 0.197
Rat
positive regulation of catabolic process GO:0009896 310 0.196
negative regulation of cell death GO:0060548 345 0.195
protein deglycosylation GO:0006517 2 0.195
negative regulation of peptidase activity GO:0010466 91 0.192
negative regulation of hydrolase activity GO:0051346 182 0.191
positive regulation of protein catabolic process GO:0045732 75 0.187
immune system development GO:0002520 195 0.183
protein k63 linked deubiquitination GO:0070536 21 0.180
regulation of cell differentiation GO:0045595 393 0.180
cellular response to misfolded protein GO:0071218 2 0.171
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.169
multicellular organismal aging GO:0010259 3 0.168
nucleoside triphosphate metabolic process GO:0009141 422 0.167
regulation of protein localization GO:0032880 296 0.163
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.163
ribonucleoside triphosphate catabolic process GO:0009203 391 0.160
locomotory behavior GO:0007626 1 0.157
purine nucleoside triphosphate catabolic process GO:0009146 392 0.154
cellular ketone metabolic process GO:0042180 80 0.151
response to radiation GO:0009314 151 0.150
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.149
thymus development GO:0048538 3 0.144
cellular polysaccharide metabolic process GO:0044264 27 0.140
i kappab kinase nf kappab signaling GO:0007249 166 0.139
glycosyl compound catabolic process GO:1901658 413 0.131
apoptotic signaling pathway GO:0097190 268 0.129
purine nucleoside monophosphate catabolic process GO:0009128 158 0.129
purine ribonucleoside catabolic process GO:0046130 398 0.127
regulation of leukocyte differentiation GO:1902105 61 0.126
neurotransmitter secretion GO:0007269 4 0.125
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.125
regulation of protein ubiquitination GO:0031396 95 0.122
receptor metabolic process GO:0043112 81 0.118
regulation of cellular ketone metabolic process GO:0010565 50 0.117
negative regulation of protein modification process GO:0031400 200 0.116
visual learning GO:0008542 1 0.114
determination of adult lifespan GO:0008340 2 0.113
ribonucleoside catabolic process GO:0042454 406 0.113
negative regulation of cell proliferation GO:0008285 228 0.113
atp catabolic process GO:0006200 157 0.111
cell development GO:0048468 328 0.109
regulation of cellular amine metabolic process GO:0033238 11 0.109
protein autoubiquitination GO:0051865 37 0.109
regulation of peptidase activity GO:0052547 180 0.108
nucleotide catabolic process GO:0009166 408 0.108
interspecies interaction between organisms GO:0044419 156 0.108
nucleoside triphosphate catabolic process GO:0009143 394 0.106
enzyme linked receptor protein signaling pathway GO:0007167 303 0.106
negative regulation of phosphate metabolic process GO:0045936 267 0.102
macroautophagy GO:0016236 39 0.102
regulation of endopeptidase activity GO:0052548 170 0.100
cellular response to dna damage stimulus GO:0006974 379 0.099
nuclear division GO:0000280 128 0.099
positive regulation of protein complex assembly GO:0031334 86 0.098
cellular response to nutrient levels GO:0031669 69 0.098
response to light stimulus GO:0009416 87 0.097
regulation of synaptic plasticity GO:0048167 3 0.096
intracellular protein transport GO:0006886 270 0.093
macromolecule glycosylation GO:0043413 63 0.093
negative regulation of protein processing GO:0010955 142 0.092
microtubule cytoskeleton organization GO:0000226 176 0.092
negative regulation of jun kinase activity GO:0043508 4 0.091
regulation of protein maturation GO:1903317 150 0.088
purine ribonucleoside metabolic process GO:0046128 437 0.088
regulation of purine nucleotide catabolic process GO:0033121 205 0.087
negative regulation of multi organism process GO:0043901 92 0.087
regulation of viral process GO:0050792 103 0.087
cellular response to decreased oxygen levels GO:0036294 51 0.087
epithelium development GO:0060429 227 0.087
cellular response to extracellular stimulus GO:0031668 72 0.086
cellular response to nitrogen compound GO:1901699 144 0.085
nervous system development GO:0007399 293 0.085
negative regulation of intracellular signal transduction GO:1902532 183 0.083
protein processing GO:0016485 226 0.082
cellular response to starvation GO:0009267 58 0.082
defense response GO:0006952 315 0.082
response to unfolded protein GO:0006986 24 0.082
ion transmembrane transport GO:0034220 338 0.081
negative regulation of multicellular organismal process GO:0051241 317 0.080
response to topologically incorrect protein GO:0035966 29 0.079
Mouse
chromatin organization GO:0006325 351 0.078
Rat
negative regulation of kinase activity GO:0033673 106 0.077
purine nucleotide catabolic process GO:0006195 405 0.077
neurological system process GO:0050877 163 0.076
positive regulation of proteolysis GO:0045862 142 0.075
regulation of immune response GO:0050776 201 0.075
microtubule based process GO:0007017 210 0.075
cellular macromolecular complex assembly GO:0034622 324 0.074
regulation of neurotransmitter secretion GO:0046928 3 0.074
actin filament based process GO:0030029 224 0.073
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.072
myeloid cell differentiation GO:0030099 117 0.072
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.072
ribonucleoside triphosphate metabolic process GO:0009199 412 0.071
cellular response to hypoxia GO:0071456 51 0.070
neuroblast proliferation GO:0007405 4 0.070
purine nucleoside monophosphate metabolic process GO:0009126 186 0.068
glucose homeostasis GO:0042593 31 0.068
establishment of organelle localization GO:0051656 59 0.068
protein glycosylation GO:0006486 62 0.065
purine nucleoside triphosphate metabolic process GO:0009144 412 0.065
nucleoside monophosphate catabolic process GO:0009125 159 0.064
positive regulation of cellular component organization GO:0051130 376 0.064
positive regulation of cell death GO:0010942 263 0.064
endosomal transport GO:0016197 129 0.064
protein modification by small protein removal GO:0070646 92 0.063
anterior posterior axis specification embryo GO:0008595 2 0.062
positive regulation of exocytosis GO:0045921 35 0.060
protein maturation GO:0051604 233 0.060
brain morphogenesis GO:0048854 1 0.059
organelle localization GO:0051640 84 0.058
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.058
positive regulation of transport GO:0051050 336 0.058
protein targeting GO:0006605 187 0.058
response to starvation GO:0042594 59 0.058
regulation of nucleoside metabolic process GO:0009118 209 0.057
epithelial cell development GO:0002064 34 0.057
inorganic ion transmembrane transport GO:0098660 231 0.057
positive regulation of cellular catabolic process GO:0031331 284 0.056
associative learning GO:0008306 1 0.056
cation transport GO:0006812 331 0.056
ion homeostasis GO:0050801 230 0.054
t cell differentiation in thymus GO:0033077 4 0.054
behavior GO:0007610 112 0.053
Mouse
negative regulation of cellular carbohydrate metabolic process GO:0010677 14 0.053
cellular response to oxygen levels GO:0071453 55 0.053
positive regulation of apoptotic process GO:0043065 246 0.052
regulation of growth GO:0040008 165 0.052
regulation of response to biotic stimulus GO:0002831 55 0.052
er nucleus signaling pathway GO:0006984 23 0.052
posttranscriptional regulation of gene expression GO:0010608 213 0.051
cation transmembrane transport GO:0098655 238 0.051
ossification GO:0001503 121 0.051
cellular response to growth factor stimulus GO:0071363 197 0.050
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
immune effector process GO:0002252 159 0.050
negative regulation of programmed cell death GO:0043069 321 0.049
myeloid dendritic cell differentiation GO:0043011 3 0.049
cellular response to peptide GO:1901653 59 0.049
leukocyte differentiation GO:0002521 98 0.048
regulation of protein serine threonine kinase activity GO:0071900 179 0.048
cellular lipid metabolic process GO:0044255 303 0.048
memory GO:0007613 3 0.048
spermatid differentiation GO:0048515 4 0.048
purine nucleoside catabolic process GO:0006152 398 0.048
negative regulation of protein maturation GO:1903318 142 0.048
regulation of establishment of protein localization GO:0070201 242 0.047
gland development GO:0048732 48 0.047
cellular response to endogenous stimulus GO:0071495 336 0.046
cell activation GO:0001775 213 0.046
blastoderm segmentation GO:0007350 2 0.046
purine containing compound catabolic process GO:0072523 411 0.045
cellular amine metabolic process GO:0044106 41 0.045
generation of precursor metabolites and energy GO:0006091 68 0.045
ribonucleoside monophosphate metabolic process GO:0009161 187 0.044
cellular carbohydrate metabolic process GO:0044262 84 0.044
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.043
response to nutrient levels GO:0031667 81 0.043
single organism reproductive process GO:0044702 98 0.043
nucleoside monophosphate metabolic process GO:0009123 191 0.043
small gtpase mediated signal transduction GO:0007264 78 0.042
anterior posterior axis specification GO:0009948 2 0.042
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.042
growth GO:0040007 202 0.042
myeloid dendritic cell activation GO:0001773 4 0.042
circulatory system development GO:0072359 262 0.041
negative regulation of phosphorus metabolic process GO:0010563 267 0.041
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.041
cerebral cortex cell migration GO:0021795 3 0.041
regulation of apoptotic signaling pathway GO:2001233 175 0.041
nucleoside catabolic process GO:0009164 408 0.039
positive regulation of secretion GO:0051047 116 0.038
generation of neurons GO:0048699 152 0.038
vesicle mediated transport GO:0016192 371 0.038
cellular amide metabolic process GO:0043603 69 0.038
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.038
transmembrane transport GO:0055085 399 0.037
protein localization to organelle GO:0033365 280 0.037
positive regulation of fat cell differentiation GO:0045600 12 0.037
regulation of cellular response to growth factor stimulus GO:0090287 76 0.037
er associated misfolded protein catabolic process GO:0071712 1 0.037
endoplasmic reticulum unfolded protein response GO:0030968 16 0.037
multi organism reproductive process GO:0044703 54 0.036
cell projection organization GO:0030030 252 0.036
tripartite regional subdivision GO:0007351 2 0.036
response to other organism GO:0051707 261 0.036
viral life cycle GO:0019058 132 0.036
calcium ion transmembrane transport GO:0070588 76 0.036
positive regulation of gtpase activity GO:0043547 166 0.036
regulation of cysteine type endopeptidase activity GO:2000116 127 0.035
notch signaling pathway GO:0007219 31 0.035
negative regulation of proteolysis GO:0045861 132 0.035
response to organonitrogen compound GO:0010243 156 0.035
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.035
ribonucleoside monophosphate catabolic process GO:0009158 158 0.035
reproductive process GO:0022414 106 0.034
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.034
response to hormone GO:0009725 175 0.034
response to peptide GO:1901652 65 0.034
regulation of viral genome replication GO:0045069 48 0.034
cellular cation homeostasis GO:0030003 163 0.034
response to tumor necrosis factor GO:0034612 76 0.034
response to transforming growth factor beta GO:0071559 94 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.034
response to abiotic stimulus GO:0009628 336 0.033
Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.033
trabecula morphogenesis GO:0061383 2 0.033
macromolecular complex disassembly GO:0032984 60 0.033
negative regulation of apoptotic process GO:0043066 316 0.033
g protein coupled receptor signaling pathway GO:0007186 207 0.033
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.032
regulation of map kinase activity GO:0043405 108 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
maintenance of location in cell GO:0051651 62 0.032
membrane organization GO:0061024 292 0.032
postreplication repair GO:0006301 12 0.032
regulation of protein complex assembly GO:0043254 147 0.032
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.032
negative regulation of protein kinase activity GO:0006469 98 0.032
cellular response to topologically incorrect protein GO:0035967 19 0.032
Mouse
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.031
signal release GO:0023061 70 0.031
divalent metal ion transport GO:0070838 152 0.031
actin cytoskeleton organization GO:0030036 207 0.031
membrane fusion GO:0061025 43 0.031
polysaccharide metabolic process GO:0005976 33 0.031
positive regulation of protein ubiquitination GO:0031398 53 0.030
spermatid development GO:0007286 4 0.030
microtubule anchoring GO:0034453 24 0.030
positive regulation of nucleotide metabolic process GO:0045981 230 0.030
negative regulation of apoptotic signaling pathway GO:2001234 97 0.030
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.030
regulation of chromosome organization GO:0033044 103 0.030
protein k63 linked ubiquitination GO:0070534 31 0.030
heart development GO:0007507 95 0.030
hair cycle GO:0042633 28 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
negative regulation of immune system process GO:0002683 136 0.030
extrinsic apoptotic signaling pathway GO:0097191 119 0.030
negative regulation of protein phosphorylation GO:0001933 140 0.030
negative regulation of myeloid cell differentiation GO:0045638 42 0.029
negative regulation of cell differentiation GO:0045596 171 0.029
cytoplasmic transport GO:0016482 379 0.029
negative regulation of developmental process GO:0051093 247 0.029
dna templated transcription elongation GO:0006354 25 0.029
regulation of antimicrobial humoral response GO:0002759 1 0.029
positive regulation of nucleotide catabolic process GO:0030813 185 0.029
response to oxygen levels GO:0070482 100 0.029
regulation of protein processing GO:0070613 150 0.028
protein monoubiquitination GO:0006513 39 0.028
regulation of vesicle mediated transport GO:0060627 130 0.028
single organism membrane fusion GO:0044801 37 0.028
organ morphogenesis GO:0009887 147 0.028
nucleotide excision repair GO:0006289 31 0.028
regulation of protein localization to nucleus GO:1900180 85 0.028
regulation of jun kinase activity GO:0043506 27 0.028
endocytosis GO:0006897 159 0.028
response to peptide hormone GO:0043434 61 0.028
carbohydrate metabolic process GO:0005975 207 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
positive regulation of developmental process GO:0051094 314 0.028
regulation of dna binding GO:0051101 37 0.028
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.028
embryonic epithelial tube formation GO:0001838 4 0.028
gtp metabolic process GO:0046039 239 0.028
regulation of carbohydrate metabolic process GO:0006109 54 0.027
vacuole organization GO:0007033 44 0.027
regulation of lipid metabolic process GO:0019216 96 0.027
macromolecule methylation GO:0043414 97 0.027
response to cytokine GO:0034097 232 0.027
translation GO:0006412 132 0.027
regulation of myeloid cell differentiation GO:0045637 81 0.027
metal ion homeostasis GO:0055065 169 0.027
cardiac ventricle morphogenesis GO:0003208 20 0.027
receptor internalization GO:0031623 43 0.027
cellular response to cytokine stimulus GO:0071345 181 0.027
regulation of exocytosis GO:0017157 46 0.026
regulation of secretion GO:0051046 194 0.026
immune response GO:0006955 307 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
lysosomal transport GO:0007041 33 0.026
ras protein signal transduction GO:0007265 73 0.026
aging GO:0007568 66 0.026
positive regulation of mapk cascade GO:0043410 190 0.026
female gamete generation GO:0007292 2 0.026
chemical homeostasis GO:0048878 306 0.026
regulation of transferase activity GO:0051338 355 0.026
cardiovascular system development GO:0072358 262 0.026
glycoprotein biosynthetic process GO:0009101 91 0.026
response to biotic stimulus GO:0009607 276 0.025
negative regulation of phosphorylation GO:0042326 174 0.025
response to hypoxia GO:0001666 96 0.025
biological adhesion GO:0022610 331 0.025
chromatin modification GO:0016568 298 0.025
Rat
stress activated protein kinase signaling cascade GO:0031098 94 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
tissue homeostasis GO:0001894 63 0.025
cellular response to unfolded protein GO:0034620 16 0.024
regulation of cellular response to stress GO:0080135 244 0.024
regulation of nervous system development GO:0051960 88 0.024
defense response to other organism GO:0098542 129 0.024
somitogenesis GO:0001756 2 0.024
negative regulation of protein deubiquitination GO:0090086 3 0.024
midbrain development GO:0030901 45 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
positive regulation of synaptic transmission GO:0050806 4 0.024
regulation of ras protein signal transduction GO:0046578 155 0.023
organelle assembly GO:0070925 176 0.023
intracellular receptor signaling pathway GO:0030522 104 0.023
stress activated mapk cascade GO:0051403 93 0.023
methylation GO:0032259 106 0.023
vasculature development GO:0001944 181 0.023
cellular calcium ion homeostasis GO:0006874 117 0.023
regulation of lipid biosynthetic process GO:0046890 47 0.023
negative regulation of endopeptidase activity GO:0010951 84 0.023
multicellular organismal response to stress GO:0033555 1 0.023
mitotic cell cycle process GO:1903047 286 0.022
regulation of exosomal secretion GO:1903541 12 0.022
response to decreased oxygen levels GO:0036293 96 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
glucan metabolic process GO:0044042 22 0.022
leukocyte activation GO:0045321 164 0.022
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.022
negative regulation of transferase activity GO:0051348 124 0.022
osteoblast differentiation GO:0001649 92 0.022
tissue regeneration GO:0042246 3 0.022
jak stat cascade GO:0007259 46 0.022
cellular response to external stimulus GO:0071496 111 0.022
t cell activation GO:0042110 99 0.022
embryo development ending in birth or egg hatching GO:0009792 34 0.022
protein polymerization GO:0051258 71 0.022
neuron differentiation GO:0030182 138 0.022
maintenance of location GO:0051235 112 0.022
organelle membrane fusion GO:0090174 5 0.022
hexose metabolic process GO:0019318 55 0.022
cellular response to organonitrogen compound GO:0071417 124 0.022
regulation of translation GO:0006417 89 0.022
lung alveolus development GO:0048286 4 0.022
synaptic vesicle exocytosis GO:0016079 3 0.021
metal ion transport GO:0030001 272 0.021
peptidyl serine phosphorylation GO:0018105 101 0.021
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.021
regulation of protein deubiquitination GO:0090085 4 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
post embryonic organ development GO:0048569 1 0.021
double strand break repair GO:0006302 101 0.021
nitrogen compound transport GO:0071705 191 0.021
regulation of small gtpase mediated signal transduction GO:0051056 156 0.021
amide biosynthetic process GO:0043604 15 0.021
ectodermal cell fate commitment GO:0001712 1 0.021
regulation of binding GO:0051098 111 0.021
positive regulation of cell cycle GO:0045787 140 0.021
cellular response to peptide hormone stimulus GO:0071375 56 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.021
viral gene expression GO:0019080 35 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.020
cellular homeostasis GO:0019725 196 0.020
regulation of secretion by cell GO:1903530 177 0.020
ameboidal type cell migration GO:0001667 135 0.020
myeloid leukocyte differentiation GO:0002573 60 0.020
cognition GO:0050890 43 0.020
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.020
nuclear envelope reassembly GO:0031468 3 0.020
neuromuscular junction development GO:0007528 3 0.020
negative regulation of leukocyte differentiation GO:1902106 24 0.020
thalamus development GO:0021794 2 0.020
regulation of protein transport GO:0051223 213 0.020
response to oxygen containing compound GO:1901700 369 0.020
glycoprotein metabolic process GO:0009100 110 0.020
covalent chromatin modification GO:0016569 254 0.019
Rat
hair cycle process GO:0022405 12 0.019
negative regulation of defense response GO:0031348 47 0.019
regulation of carbohydrate biosynthetic process GO:0043255 27 0.019
retina vasculature development in camera type eye GO:0061298 3 0.019
protein acylation GO:0043543 138 0.019
cytokine production GO:0001816 247 0.019
translational initiation GO:0006413 48 0.019
oogenesis GO:0048477 2 0.019
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.019
microtubule based movement GO:0007018 32 0.019
hair follicle maturation GO:0048820 3 0.019
tissue morphogenesis GO:0048729 96 0.019
atp metabolic process GO:0046034 176 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
positive regulation of immune response GO:0050778 159 0.019
protein k48 linked ubiquitination GO:0070936 38 0.019
attachment of spindle microtubules to kinetochore GO:0008608 17 0.019
synaptic transmission GO:0007268 61 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
single organism membrane organization GO:0044802 268 0.018
peptide metabolic process GO:0006518 51 0.018
cellular glucan metabolic process GO:0006073 22 0.018
viral genome replication GO:0019079 50 0.018
organelle fusion GO:0048284 36 0.018
fat cell differentiation GO:0045444 32 0.018
anatomical structure homeostasis GO:0060249 100 0.018
regulation of heart morphogenesis GO:2000826 4 0.018
head development GO:0060322 108 0.018
regeneration GO:0031099 4 0.018
negative regulation of protein localization to nucleus GO:1900181 34 0.018
cation homeostasis GO:0055080 189 0.018
epithelial cell proliferation GO:0050673 128 0.018
regulation of ubiquitin protein transferase activity GO:0051438 28 0.017
apoptotic mitochondrial changes GO:0008637 57 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
cellular chemical homeostasis GO:0055082 180 0.017
mitotic sister chromatid segregation GO:0000070 53 0.017
regulation of receptor mediated endocytosis GO:0048259 32 0.017
single organism cell adhesion GO:0098602 179 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
regulation of immune effector process GO:0002697 91 0.017
mitotic metaphase plate congression GO:0007080 14 0.017
epidermis development GO:0008544 59 0.017
regulation of atp metabolic process GO:1903578 29 0.017
glycosylation GO:0070085 71 0.017
molting cycle process GO:0022404 12 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
positive regulation of peptidase activity GO:0010952 88 0.016
histone acetylation GO:0016573 93 0.016
regulation of myeloid leukocyte differentiation GO:0002761 39 0.016
cell cell signaling GO:0007267 155 0.016
exocytosis GO:0006887 71 0.016

ATXN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.163
central nervous system disease DOID:331 186 0.095
neurodegenerative disease DOID:1289 102 0.095
nervous system disease DOID:863 431 0.095
muscular disease DOID:0080000 114 0.095
muscle tissue disease DOID:66 113 0.095
cancer DOID:162 167 0.087
disease of cellular proliferation DOID:14566 174 0.087
organ system cancer DOID:0050686 164 0.087
myopathy DOID:423 104 0.031
heart disease DOID:114 68 0.027
cardiomyopathy DOID:0050700 50 0.027
intrinsic cardiomyopathy DOID:0060036 50 0.027
cardiovascular system disease DOID:1287 106 0.027
disease of mental health DOID:150 70 0.026
cognitive disorder DOID:1561 29 0.023
brain disease DOID:936 73 0.018