Homo sapiens

97 known processes

SMC3

structural maintenance of chromosomes 3

(Aliases: CDLS3,HCAP,SMC3L1,BMH,CSPG6,BAM)

SMC3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sister chromatid cohesion GO:0007062 24 0.995
mitotic sister chromatid segregation GO:0000070 53 0.988
Yeast Zebrafish
meiotic chromosome segregation GO:0045132 4 0.975
Yeast
mitotic cell cycle GO:0000278 326 0.975
sister chromatid segregation GO:0000819 54 0.975
Yeast Zebrafish
negative regulation of dna endoreduplication GO:0032876 5 0.966
organelle fission GO:0048285 149 0.965
mitotic sister chromatid cohesion GO:0007064 12 0.960
Yeast Zebrafish
negative regulation of dna replication GO:0008156 29 0.952
double strand break repair GO:0006302 101 0.913
Yeast
mitotic cell cycle process GO:1903047 286 0.895
mitotic nuclear division GO:0007067 119 0.894
Yeast Zebrafish
negative regulation of cell cycle GO:0045786 193 0.877
nuclear division GO:0000280 128 0.867
dna replication GO:0006260 116 0.855
post embryonic development GO:0009791 2 0.846
chromosome segregation GO:0007059 114 0.838
positive regulation of cellular component organization GO:0051130 376 0.823
regulation of cell cycle process GO:0010564 266 0.781
regulation of chromosome segregation GO:0051983 44 0.776
cellular response to dna damage stimulus GO:0006974 379 0.735
Yeast
cell division GO:0051301 168 0.695
Worm
chromatin assembly or disassembly GO:0006333 78 0.664
regulation of sister chromatid cohesion GO:0007063 9 0.644
regulation of dna metabolic process GO:0051052 153 0.625
negative regulation of developmental process GO:0051093 247 0.598
Mouse
vesicle mediated transport GO:0016192 371 0.590
Worm
cohesin localization to chromatin GO:0071921 4 0.575
dna repair GO:0006281 198 0.523
Yeast
regulation of cell cycle GO:0051726 393 0.495
metaphase anaphase transition of cell cycle GO:0044784 21 0.487
protein localization to chromatin GO:0071168 11 0.483
dna dependent dna replication GO:0006261 44 0.448
regulation of mitotic sister chromatid separation GO:0010965 27 0.448
negative regulation of organelle organization GO:0010639 126 0.438
meiotic nuclear division GO:0007126 10 0.379
protein dna complex subunit organization GO:0071824 80 0.356
negative regulation of chromosome organization GO:2001251 48 0.351
dna conformation change GO:0071103 113 0.341
Worm
regulation of meiotic cell cycle GO:0051445 4 0.341
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.333
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.329
negative regulation of cell cycle process GO:0010948 121 0.318
regulation of dna replication GO:0006275 68 0.311
cell cycle g1 s phase transition GO:0044843 80 0.308
regulation of chromatin modification GO:1903308 51 0.291
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.283
reproductive process GO:0022414 106 0.277
Yeast Worm
meiotic cell cycle GO:0051321 13 0.274
meiotic cell cycle process GO:1903046 8 0.269
Yeast
regulation of chromosome organization GO:0033044 103 0.265
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.264
cell cycle phase transition GO:0044770 173 0.249
single organism reproductive process GO:0044702 98 0.246
Yeast Worm
mitotic cell cycle phase transition GO:0044772 162 0.229
negative regulation of dna metabolic process GO:0051053 57 0.224
regulation of mitosis GO:0007088 63 0.217
developmental process involved in reproduction GO:0003006 66 0.216
Yeast Worm
negative regulation of chromosome segregation GO:0051985 18 0.207
gonad development GO:0008406 34 0.202
Worm
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.198
mitotic sister chromatid separation GO:0051306 18 0.195
regulation of cell cycle phase transition GO:1901987 126 0.194
reproductive system development GO:0061458 56 0.190
Worm
positive regulation of mitotic cell cycle GO:0045931 60 0.189
chromosome separation GO:0051304 23 0.180
centrosome organization GO:0051297 58 0.164
mitotic cell cycle checkpoint GO:0007093 68 0.159
cell cycle checkpoint GO:0000075 117 0.155
nucleosome assembly GO:0006334 50 0.155
embryo development GO:0009790 123 0.150
Worm
regulation of response to dna damage stimulus GO:2001020 94 0.149
receptor mediated endocytosis GO:0006898 84 0.149
Worm
regulation of mitotic cell cycle GO:0007346 189 0.147
regulation of protein localization GO:0032880 296 0.144
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.131
reproductive structure development GO:0048608 55 0.127
Worm
negative regulation of protein processing GO:0010955 142 0.125
chromatin remodeling GO:0006338 55 0.124
regulation of mitotic sister chromatid segregation GO:0033047 27 0.124
g1 s transition of mitotic cell cycle GO:0000082 78 0.117
reproduction GO:0000003 63 0.115
chromatin assembly GO:0031497 61 0.114
ubiquitin dependent protein catabolic process GO:0006511 206 0.112
oogenesis GO:0048477 2 0.111
positive regulation of cell division GO:0051781 59 0.109
organelle localization GO:0051640 84 0.108
protein localization to organelle GO:0033365 280 0.108
protein modification by small protein removal GO:0070646 92 0.107
regulation of dna dependent dna replication GO:0090329 19 0.107
positive regulation of organelle organization GO:0010638 195 0.101
single organism cellular localization GO:1902580 332 0.098
regulation of cell differentiation GO:0045595 393 0.092
Mouse
sex differentiation GO:0007548 45 0.086
Worm
positive regulation of apoptotic process GO:0043065 246 0.086
negative regulation of cellular component organization GO:0051129 235 0.086
regulation of nuclear division GO:0051783 65 0.081
development of primary sexual characteristics GO:0045137 35 0.080
Worm
regulation of protein transport GO:0051223 213 0.079
negative regulation of mitotic cell cycle GO:0045930 102 0.077
female gamete generation GO:0007292 2 0.076
regulation of cell division GO:0051302 116 0.075
regulation of proteolysis GO:0030162 293 0.074
brain development GO:0007420 97 0.072
embryo development ending in birth or egg hatching GO:0009792 34 0.072
Worm
negative regulation of cell proliferation GO:0008285 228 0.072
regulation of mitotic cell cycle phase transition GO:1901990 118 0.072
positive regulation of cell cycle GO:0045787 140 0.071
negative regulation of cellular protein metabolic process GO:0032269 353 0.070
protein maturation GO:0051604 233 0.070
regulation of protein catabolic process GO:0042176 155 0.067
cellular protein catabolic process GO:0044257 261 0.067
positive regulation of proteolysis GO:0045862 142 0.066
positive regulation of dna metabolic process GO:0051054 73 0.065
regulation of cellular protein catabolic process GO:1903362 96 0.064
rna splicing GO:0008380 131 0.064
cellular amino acid metabolic process GO:0006520 116 0.063
regulation of cohesin localization to chromatin GO:0071922 4 0.063
regulation of proteasomal protein catabolic process GO:0061136 87 0.062
response to abiotic stimulus GO:0009628 336 0.061
regulation of protein processing GO:0070613 150 0.061
positive regulation of mitosis GO:0045840 25 0.060
microtubule based process GO:0007017 210 0.059
endocytosis GO:0006897 159 0.058
Worm
generation of neurons GO:0048699 152 0.058
protein depolymerization GO:0051261 30 0.058
nucleosome organization GO:0034728 66 0.057
modification dependent macromolecule catabolic process GO:0043632 212 0.057
cell development GO:0048468 328 0.057
Yeast Mouse
regulation of cellular amino acid metabolic process GO:0006521 6 0.057
cell projection organization GO:0030030 252 0.056
central nervous system development GO:0007417 123 0.055
nucleus organization GO:0006997 28 0.054
spermatid development GO:0007286 4 0.054
regulation of dna templated transcription initiation GO:2000142 9 0.054
negative regulation of cell division GO:0051782 31 0.053
negative regulation of protein metabolic process GO:0051248 391 0.052
cell morphogenesis GO:0000902 296 0.051
intrinsic apoptotic signaling pathway GO:0097193 127 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.049
proteasomal protein catabolic process GO:0010498 176 0.048
regulation of sister chromatid segregation GO:0033045 27 0.046
mrna processing GO:0006397 133 0.045
organelle assembly GO:0070925 176 0.044
positive regulation of cell cycle process GO:0090068 106 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.041
response to radiation GO:0009314 151 0.041
cell part morphogenesis GO:0032990 137 0.040
purine nucleoside monophosphate metabolic process GO:0009126 186 0.040
chromatin modification GO:0016568 298 0.039
multicellular organismal reproductive process GO:0048609 40 0.039
negative regulation of cellular protein catabolic process GO:1903363 38 0.039
chromosome condensation GO:0030261 15 0.038
Worm
regulation of nucleocytoplasmic transport GO:0046822 98 0.038
positive regulation of cellular component biogenesis GO:0044089 158 0.038
skeletal system development GO:0001501 79 0.038
blastocyst development GO:0001824 3 0.037
negative regulation of cell differentiation GO:0045596 171 0.037
Mouse
regulation of binding GO:0051098 111 0.037
regulation of establishment of protein localization GO:0070201 242 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
negative regulation of mitosis GO:0045839 24 0.036
sensory perception GO:0007600 103 0.035
centrosome cycle GO:0007098 32 0.034
regulation of meiosis GO:0040020 3 0.034
negative regulation of proteolysis GO:0045861 132 0.034
positive regulation of growth GO:0045927 58 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.032
tube development GO:0035295 125 0.032
nucleotide catabolic process GO:0009166 408 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
cellular ketone metabolic process GO:0042180 80 0.030
detection of mechanical stimulus GO:0050982 4 0.030
ribonucleoside monophosphate catabolic process GO:0009158 158 0.030
cytokinesis GO:0000910 96 0.030
Worm
regulation of cellular amine metabolic process GO:0033238 11 0.030
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.029
dna integrity checkpoint GO:0031570 71 0.029
apoptotic signaling pathway GO:0097190 268 0.029
positive regulation of developmental process GO:0051094 314 0.029
nucleic acid transport GO:0050657 39 0.028
protein processing GO:0016485 226 0.027
negative regulation of cell death GO:0060548 345 0.027
cell projection morphogenesis GO:0048858 129 0.026
microtubule cytoskeleton organization GO:0000226 176 0.026
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.026
regulation of protein maturation GO:1903317 150 0.025
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.025
stem cell development GO:0048864 69 0.025
Mouse
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.025
microtubule organizing center organization GO:0031023 62 0.025
positive regulation of programmed cell death GO:0043068 249 0.024
atp metabolic process GO:0046034 176 0.024
response to nitrogen compound GO:1901698 184 0.024
dna packaging GO:0006323 77 0.024
Worm
nuclear export GO:0051168 69 0.023
nervous system development GO:0007399 293 0.023
head development GO:0060322 108 0.023
mrna transport GO:0051028 30 0.022
negative regulation of protein maturation GO:1903318 142 0.022
positive regulation of cell death GO:0010942 263 0.022
amine metabolic process GO:0009308 44 0.022
multi organism behavior GO:0051705 14 0.022
nucleoside catabolic process GO:0009164 408 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.021
regulation of chromatin organization GO:1902275 56 0.021
methylation GO:0032259 106 0.020
axoneme assembly GO:0035082 3 0.020
cellular macromolecular complex assembly GO:0034622 324 0.020
response to uv GO:0009411 73 0.020
gene silencing by rna GO:0031047 26 0.020
system process GO:0003008 349 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
negative regulation of sister chromatid segregation GO:0033046 17 0.020
negative regulation of apoptotic process GO:0043066 316 0.019
locomotory behavior GO:0007626 1 0.019
positive regulation of protein complex assembly GO:0031334 86 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
positive regulation of chromosome organization GO:2001252 41 0.019
metaphase plate congression GO:0051310 18 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
negative regulation of catalytic activity GO:0043086 335 0.018
cilium morphogenesis GO:0060271 75 0.018
growth GO:0040007 202 0.018
ameboidal type cell migration GO:0001667 135 0.018
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.018
microtubule polymerization or depolymerization GO:0031109 37 0.018
protein localization to chromosome GO:0034502 30 0.018
chromatin organization GO:0006325 351 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
signal transduction in response to dna damage GO:0042770 57 0.018
protein acetylation GO:0006473 116 0.017
regulation of cell morphogenesis GO:0022604 153 0.017
intracellular protein transport GO:0006886 270 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
neuroblast proliferation GO:0007405 4 0.017
multi multicellular organism process GO:0044706 18 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
peptidyl lysine modification GO:0018205 144 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
circulatory system development GO:0072359 262 0.016
nucleoside monophosphate catabolic process GO:0009125 159 0.016
heterochromatin assembly GO:0031507 6 0.016
dephosphorylation GO:0016311 209 0.016
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.016
oocyte development GO:0048599 1 0.016
positive regulation of nuclear division GO:0051785 27 0.015
heterochromatin organization GO:0070828 6 0.015
regulation of protein complex assembly GO:0043254 147 0.015
regulation of cellular response to stress GO:0080135 244 0.015
cellular component morphogenesis GO:0032989 314 0.015
histone lysine methylation GO:0034968 50 0.015
taxis GO:0042330 157 0.015
nucleobase containing compound transport GO:0015931 51 0.015
positive regulation of chromatin modification GO:1903310 30 0.015
response to ionizing radiation GO:0010212 65 0.015
circadian sleep wake cycle process GO:0022410 2 0.015
rna transport GO:0050658 39 0.015
neuromuscular junction development GO:0007528 3 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
actin cytoskeleton organization GO:0030036 207 0.014
mitotic spindle checkpoint GO:0071174 18 0.014
innate immune response GO:0045087 178 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
regulation of microtubule based process GO:0032886 74 0.013
regulation of dna repair GO:0006282 47 0.013
positive regulation of immune system process GO:0002684 283 0.012
dna templated transcription initiation GO:0006352 35 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
spindle organization GO:0007051 53 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
positive regulation of response to dna damage stimulus GO:2001022 43 0.012
multicellular organism reproduction GO:0032504 42 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
response to other organism GO:0051707 261 0.012
mitotic spindle assembly checkpoint GO:0007094 14 0.012
membrane organization GO:0061024 292 0.012
protein oligomerization GO:0051259 173 0.012
genitalia development GO:0048806 10 0.011
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
negative regulation of catabolic process GO:0009895 104 0.011
actin filament based process GO:0030029 224 0.011
regulation of translation GO:0006417 89 0.011
positive regulation of protein catabolic process GO:0045732 75 0.011
regulation of chromatin assembly GO:0010847 2 0.011
negative regulation of dna dependent dna replication GO:2000104 9 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
regulation of intracellular transport GO:0032386 195 0.010
immune response GO:0006955 307 0.010
regulation of histone modification GO:0031056 47 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010
protein dna complex assembly GO:0065004 64 0.010
protein catabolic process GO:0030163 325 0.010
pyrimidine nucleoside triphosphate metabolic process GO:0009147 2 0.010

SMC3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cornelia de lange syndrome DOID:11725 5 0.000